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High production of type VI collagen in multiple fibromatosis with multiple articular dysplasia.

Abstract：

:A patient with multiple fibromatosis occurring at the sites of multiple cartilagenous dysplasia was described. Collagen types solubilized with pepsin from the fibromatous tissue were fractionated by a different salt concentration and analyzed by SDS-polyacrylamide gel electrophoresis, which indicated that the tissue produces predominantly "short-chain" collagen. Western blotting of the subunits indicated a cross reaction with antisera of the type VI collagen. The results of rotatory shadowing electron microscopy confirmed the characteristic short-chain structure.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Murata K,Motoyama T,Suka M,Ohno M,Kuboki Y

doi

10.1016/s0006-291x(87)80117-1

subject

Has Abstract

pub_date

1987-08-31 00:00:00

pages

275-81

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(87)80117-1

journal_volume

147

pub_type

杂志文章

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