Abstract:
OBJECTIVE:The objectives of this study were to determine 1) whether the extent of weight loss is predictive of the degree of changes in hormone and lipid levels; 2) the interactions between energy regulating hormones after weight loss through an energy deficit/exercise protocol diet and exercise; 3) whether initial metabolic parameters are indicative of the extent of weight loss. METHODS:Thirty-five hyperlipidemic females (BMI 28-39 kg/m2) 35-60 years old participated in a six month weight loss trial. Weight loss resulted from a diet and exercise program that when combined produced a 30% energy deficit. Fasting plasma taken during 2 wk stabilization periods at the beginning and end of the study was analysed for lipids, hormone and glucose levels. RESULTS:Average weight loss was 11.7 +/- 2.5 kg (p < 0.0001). TC, LDL-C, and triacylglycerols decreased 9.3 +/- 9.5% (p < 0.0001), 7.4 +/- 12.2% (p < 0.001), and 26.8 +/- 19.6% (p < 0.05), respectively, while HDL-C increased (p < 0.05) by 8.2 +/- 16.3%. Leptin levels declined (p < 0.001) 48.9 +/- 16.0% and ghrelin levels rose (p < 0.001) 21.2 +/- 26.7%. While overall levels of adiponectin did not differ, individual values changed such that weight loss predicted increases in adiponectin levels. Though initial weight did not predict weight loss, baseline lipid and insulin levels positively predicted weight loss. CONCLUSION:Initial metabolic parameters may be predictors of weight loss. Beneficial effects of weight loss as achieved through diet and exercise on measured parameters indicate moderate weight loss reduces key risk factors of cardiovascular disease in overweight individuals.
journal_name
J Am Coll Nutrjournal_title
Journal of the American College of Nutritionauthors
Santosa S,Demonty I,Lichtenstein AH,Cianflone K,Jones PJdoi
10.1080/07315724.2007.10719608subject
Has Abstractpub_date
2007-06-01 00:00:00pages
250-8issue
3eissn
0731-5724issn
1541-1087pii
26/3/250journal_volume
26pub_type
杂志文章abstract:OBJECTIVE:We studied the relationship between maternal and cord plasma concentrations of carotenoids, retinol, and tocopherols in normal mother-baby pairs. METHODS:Healthy pregnant women (n = 10) were recruited at a Montréal hospital. Venous blood samples were collected from the mothers at delivery and cord blood was ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1998.10718791
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVES:These studies investigated the ability of a hydroxychalcone from cinnamon to function as an insulin mimetic in 3T3-LI adipocytes. METHODS:Comparative experiments were performed with the cinnamon methylhydroxychalcone polymer and insulin with regard to glucose uptake, glycogen synthesis. phosphatidylinositol...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2001.10719053
更新日期:2001-08-01 00:00:00
abstract::Following a lymphocyte separation technique, the lymphocyte content of magnesium and potassium was determined by atomic absorption spectroscopy in 28 subjects. Simultaneously, skeletal muscle biopsies were obtained by a percutaneous technique and analyzed for magnesium and potassium. In this study there was not signif...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1985.10720104
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVES:In adults, adaptation to changes in magnesium intake is largely due to changes in fractional magnesium absorption and urinary magnesium excretion. We sought to examine whether these homeostatic mechanism also occurred in young children. METHODS:Children, 12-48 m old were studied (n=30). They were adapted to...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2008.10719711
更新日期:2008-04-01 00:00:00
abstract::The dietary intake (assessed through dietary history) of 539 apparently healthy, independently living elderly aged 65-79 years, was evaluated in a nationwide random sample. Except for pyridoxine, the intake of vitamins, minerals, and water was adequate according to the Dutch recommended dietary allowances. Fat intake ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.1989.10720310
更新日期:1989-08-01 00:00:00
abstract::A simple procedure has been developed for preparation of animal tissues and diet mixtures for Mg and Ca analysis by atomic absorption spectroscopy. This procedure involves wet ashing in warm 30% hydrogen peroxide and extraction of metals, from the dried ash, into cold, dilute nitric acid. Less than 200 mg of tissue or...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1983.10719920
更新日期:1983-01-01 00:00:00
abstract::Exogenous, microbial beta-D-galactosidases are capable of effecting hydrolysis of lactose in situ in the gastrointestinal tract of lactase-deficient subjects when given as replacement therapy at mealtime. As its digestion products-glucose and galactose-are known to inhibit lactose hydrolysis in vitro, the effect of ad...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1986.10720131
更新日期:1986-01-01 00:00:00
abstract::Agricultural biotechnology has been widely adopted in agriculture but is also the focus of controversy. Questions have arisen regarding food and environmental safety. In the US, responsibility for ensuring agricultural and environmental safety is delegated to the USDA and EPA, respectively. The FDA has primary respons...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.2002.10719261
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVES:The effects of a new resistant dextrin ingested at breakfast on day-long metabolic parameters and ghrelin profile at subsequent lunch were investigated. METHODS:In this randomized, single-blinded, crossover study, 12 healthy men ingested a standardized breakfast with 50 g of NUTRIOSE 10, a resistant dextrin...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1080/07315724.2011.10719945
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE AND METHODS:We reviewed records of 41 children with treated phenylketonuria (PKU) in order to evaluate hematopoiesis and the effect of iron and protein sufficiency. RESULTS:Six children (15%) were found to have anemia. Combined depletion of iron and protein stores was most likely to result in anemia, and two...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2001.10719016
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:The role of dietary glycemic index (GI) and glycemic load (GL) in the development of obesity has been debated globally. The relationship with body shape and fat distribution was examined in this cross-sectional association study among apparently healthy Iranian adults. METHODS AND MATERIALS:A study populatio...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2017.1416312
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:We examined relationships of individual and environmental factors with obesity and trying to lose weight in rural residents. METHODS:The joint contributions of individual and environmental factors on obesity status (obese vs. morbidly obese) and trying to lose weight (yes vs. no) were evaluated using general...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2007.10719632
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the effect of dietary restriction on tissue distribution of vitamin B-6 vitamers and activities of vitamin B-6 metabolizing enzymes in rats. METHODS:Male rats were subjected to a 40% dietary restriction for 10, 20 or 40 weeks. The tissue vitamin B-6 vitamer concentrati...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1999.10718842
更新日期:1999-04-01 00:00:00
abstract:UNLABELLED:Many publications indicate the beneficial effect of n-6 polyunsaturated fatty acids (n-6 PUFAs) in the control of coronary heart disease and diabetes, although the mechanism is not clear. Some of our previous results suggest that, in contrast to other lipids, n-6 PUFAs could have a permissive effect on carbo...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1987.10720202
更新日期:1987-10-01 00:00:00
abstract::An inhibitor of folate metabolism, amethopterin (methotrexate) has been successfully used in the treatment of psoriasis and neoplastic disease. This drug produces several dangerous side effects of both an acute and chronic nature which have widely curtailed its use. A serious chronic side effect of the drug is its hep...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1984.10720041
更新日期:1984-01-01 00:00:00
abstract::Following massive small bowel resection, the remaining small bowel increases in mucosal weight, protein, deoxyribonucleic acid (DNA) content and absorptive function. Enteral nutrients are known to be important in stimulating this response. Recently, glutamine has been described as an essential fuel for the small intes...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVE:The present study evaluated the effects of repeated-sprint training in normobaric hypoxia and β-alanine supplementation (BA) on aerobic and anaerobic performance in recreationally active men. METHODS:Participants were randomly assigned to one of the following groups: normoxia/β-alanine (NB, n = 11), normoxia...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1080/07315724.2018.1475269
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:Previous interventions have reported desirable effects of diets rich in whole grains or rich in fruits and vegetables on cardiovascular disease (CVD) risk factors and weight management. However, data are lacking regarding the effect of these fiber sources separately. The aim of this randomized clinical feedin...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1080/07315724.2018.1444520
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:In Sprague-Dawley rats (SD), we compared two categories of natural dietary supplements that influence carbohydrate (CHO) metabolism via different basic mechanisms to ameliorate insulin resistance (IR) and elevated blood pressure (BP) associated with heavy sugar/starch consumption. Two dietary supplements (bea...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2013.770335
更新日期:2013-01-01 00:00:00
abstract::Objective: To evaluate whether the Fat-to-Lean Mass (FyM) ratio is associated to hyperinsulinemia in healthy adolescents.Methods: Apparently healthy adolescents aged 10 to 15 years that according to sex, age, and percentiles of body fat percent, were included and allocated into the groups with elevated (body fat perce...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2020.1752845
更新日期:2020-10-12 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate whether probiotics had an effect on proinflammatory markers and cytokines in overweight and obese individuals and whether they could have synergistic effects with weight-loss diets. METHODS:A total of 75 healthy overweight and obese individuals completed this ran...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1080/07315724.2013.874937
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:The Health Focus National Study of Public Attitudes and Actions Toward Healthy Foods is conducted every two years to identify current issues in consumer health and nutrition behavior and attitudes, to assess the trends in consumer priorities and to develop an understanding of where consumers are headed in the...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2000.10718973
更新日期:2000-10-01 00:00:00
abstract::The acquisition and maintenance of bone mass and strength are influenced by environmental factors, including physical activity and nutrition. Among micronutrients, calcium (Ca) and inorganic (i) phosphate (P) are the two main constituents of hydroxyapatite, the bone mineral that strengthens the mechanical resistance o...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.2011.10719988
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To estimate the association of anembryonic pregnancy with 55 elements, homocysteine, folate and S-adenosylhomocysteine in pregnant women. METHODS:Thirty cases of anembryonic pregnancy were diagnosed using ultrasound scanning that showed an empty gestation sac with no embryo pole in the uterus. Additionally, ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2009.10719761
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:Historically diet and arthritis have been cause/effect associated but the idea is controversial with little evidence that specific diet components are effective treatment. This controlled, double-blinded, crossover study reports the effect of folate and cobalamin supplements in 26 humans diagnosed for an aver...
journal_title:Journal of the American College of Nutrition
pub_type: 临床试验,杂志文章
doi:10.1080/07315724.1994.10718421
更新日期:1994-08-01 00:00:00
abstract::Magnesium balance, and plasma and urinary levels, were studied in spontaneously hypertensive (SHR), Wistar Kyoto (WKY) and in Wistar (WI) rats. We found few differences in the measured parameters between WKY and WI rats, but the SHR rat which similarly maintained Mg balance has lower plasma Mg levels and less urinary ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1987.10720195
更新日期:1987-08-01 00:00:00
abstract::No single study or avenue of investigation can resolve the scientific controversies that entangle efforts to determine the effects of specific nutrients on medical conditions. To reach consensus in this area requires a substantial body of plausible, reproducible and consistent data from various investigative approache...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.1999.10718904
更新日期:1999-10-01 00:00:00
abstract::T-lymphocyte subpopulations were measured in the two major types of adult malnutrition, adult marasmus and kwashiorkor-like hypoalbuminemic malnutrition. The population of T-cells (T3) and the percentage of both helper (T4) and suppressor (T8) T-cells were significantly (P less than .05) decreased in patients with kwa...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1986.10720158
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Boron is an essential micronutrient for higher plants. The results of studies in animals and humans have suggested a potential role for boron as a modulator of the steroid hormone pathway. METHODS:As part of a study to obtain baseline information on boron in humans, the boron content of selected foods (66 i...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1996.10718638
更新日期:1996-12-01 00:00:00
abstract:BACKGROUND:The Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate, provided extensive tables of data on total water intake, water intake from beverages and water intake from foods; however, very little information was provided about the specific details of these analyses. Reported total water...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2007.10719663
更新日期:2007-10-01 00:00:00