Depression type and depression severity in relation to risk of violent suicide attempt.

Abstract:

:Low levels of cerebrospinal fluid 5-hydroxyindoleacetic acid and a blunted thyroid-stimulating hormone response to thyrotropin-releasing hormone have been reported in depressed patients--in particular in those who have made violent suicide attempts. There are at least two conceivable explanations for these findings: The biological abnormalities relate to (1) disturbed aggression regulation or to (2) disturbed mood regulation (either type or severity). The second alternative presupposes that violent suicide attempts occur differentially in a particular depression type or differentially in severe depression. This study demonstrated that violent suicide attempts are "depression-specific," i.e., they relate to a particular depressive syndrome, that of vital depression, but not to the severity factor. Therefore, it is impossible to decide whether the biological abnormalities in depressed, violent suicide attempters relate to a particular type of mood disorder or to a distorted regulation of aggression.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

van Praag HM,Plutchik R

doi

10.1016/0165-1781(84)90049-0

subject

Has Abstract

pub_date

1984-08-01 00:00:00

pages

333-8

issue

4

eissn

0165-1781

issn

1872-7123

pii

0165-1781(84)90049-0

journal_volume

12

pub_type

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