Microvascular endothelial cells exhibit optimal aspect ratio for minimizing flow resistance.

abstract：:Recent studies have demonstrated the ability of magnetic resonance imaging (MRI) to provide anatomically realistic boundary conditions for computational fluid dynamics (CFD) simulations of arterial hemodynamics. To date, however, little is known about the overall reproducibility of such image-based CFD techniques. Tow...

journal_title：Annals of biomedical engineering

authors： Thomas JB,Milner JS,Rutt BK,Steinman DA

更新日期：2003-02-01 00:00:00

abstract：:The field of tissue engineering promises to deliver biological substitutes to repair or replace tissues in the body that have been injured or diseased. The clinical demand for musculoskeletal tissues is particularly high, especially for cartilage and bone defects. Although they are generally considered biologically si...

journal_title：Annals of biomedical engineering

authors： Sharma B,Elisseeff JH

更新日期：2004-01-01 00:00:00

abstract：:Calcium phosphate ceramics have been widely used for filling bone defects to aid in the regeneration of new bone tissue. Addition of osteogenic cells to porous ceramic scaffolds may accelerate the bone repair process. This study demonstrates the feasibility of culturing marrow stromal cells (MSCs) on porous biphasic c...

journal_title：Annals of biomedical engineering

authors： Holtorf HL,Sheffield TL,Ambrose CG,Jansen JA,Mikos AG

更新日期：2005-09-01 00:00:00

abstract：:The responses of photoreceptor cells to moving stimuli are crucial to understanding motion detection in visual systems. However, these responses are not well characterized quantitatively because they result from a combination of spatial optical behavior in the lens systems with temporal behavior in the phototransducti...

journal_title：Annals of biomedical engineering

authors： Korenberg MJ,Juusola M,French AS

更新日期：1998-03-01 00:00:00

abstract：:We and others have shown that changing surface characteristics of the spacer implanted during the first Masquelet stage alters some aspects of membrane development. Previously we demonstrated that titanium (TI) spacers create membranes that are better barriers to movement of solutes > 70 kDa in size than polymethyl me...

journal_title：Annals of biomedical engineering

authors： Toth Z,Roi M,Evans E,Watson JT,Nicolaou D,McBride-Gagyi S

更新日期：2019-01-01 00:00:00

abstract：:In vitro and in vivo studies were conducted on omega-3 fatty acid-derived biomaterials to determine their utility as an implantable material for adhesion prevention following soft tissue hernia repair and as a means to allow for the local delivery of antimicrobial or antibiofilm agents. Naturally derived biomaterials ...

journal_title：Annals of biomedical engineering

authors： Faucher KM,Artzi N,Beck M,Beckerman R,Moodie G,Albergo T,Conroy S,Dale A,Corbeil S,Martakos P,Edelman ER

更新日期：2016-03-01 00:00:00

abstract：:While considerable efforts have been expended to develop snore-driven markers for detecting obstructive sleep apnea (OSA), there is little emphasis on the relationship between the human upper airway (UA) dimensions and the attributes of snores. This paper aims to investigate the acoustical and perceptual impacts of ch...

journal_title：Annals of biomedical engineering

authors： Ng AK,Koh TS,Baey E,Puvanendran K

更新日期：2009-09-01 00:00:00

abstract：:Polycrystalline silicon (poly-Si) micromechanical structures can be made by selectively etching an underlying sacrificial oxide layer. Advantages of this micromachining technique are its simplicity and compatibility with conventional integrated-circuit processing. Compressive internal stress in poly-Si films constrain...

journal_title：Annals of biomedical engineering

authors： Howe RT

更新日期：1986-01-01 00:00:00

abstract：:Fractal time series analysis methods are commonly used for analyzing center of pressure (COP) signals with the goal of revealing the underlying neuromuscular processes for upright stance control. The use of fractal methods is often coupled with the assumption that the COP is an instance of fractional Gaussian noise (f...

journal_title：Annals of biomedical engineering

authors： Kuznetsov N,Bonnette S,Gao J,Riley MA

更新日期：2013-08-01 00:00:00

abstract：:Typical inverse dynamics approaches to the calculation of muscle, ligament, and joint contact forces are based on a step-wise solution of the equations of motion. This approach is therefore limited in its ability to provide insight as to the muscular, ligamentous, and articular interactions that create joint stability...

journal_title：Annals of biomedical engineering

authors： Cleather DJ,Bull AM

更新日期：2011-07-01 00:00:00

abstract：:To better understand oxygen utilization by the retina, a mathematical model of oxygen diffusion and consumption in the cat outer, avascular retina was developed by analyzing previously recorded profiles of oxygen tension (PO2) as a function of retinal depth. Simple diffusion modelling of the oxygen distribution throug...

journal_title：Annals of biomedical engineering

authors： Haugh LM,Linsenmeier RA,Goldstick TK

更新日期：1990-01-01 00:00:00

abstract：:The most widely implanted prosthetic valve is the mechanical bileaflet. Recent clinical experiences suggest that some designs are more prone to thromboembolic episodes than others. This study evaluated the hinge flow and near-field forward flow of the new St. Jude Medical Regent bileaflet mechanical heart valve. Laser...

journal_title：Annals of biomedical engineering

authors： Ellis JT,Travis BR,Yoganathan AP

更新日期：2000-05-01 00:00:00

abstract：:There is a high incidence of low back pain (LBP) associated with occupations requiring sustained and/or repetitive lumbar flexion (SLF and RLF, respectively), which cause creep of the viscoelastic tissues. The purpose of this study was to determine the effect of creep on lumbar biomechanics and facet joint capsule (FJ...

journal_title：Annals of biomedical engineering

authors： Little JS,Khalsa PS

更新日期：2005-03-01 00:00:00

abstract：:Defining the constituent regulatory molecules in tendon is critical to understanding the process of tendon repair and instructive to the development of novel treatment modalities. The purpose of this study is to define the structural, expressional, and mechanical changes in the tendon injury response, and elucidate th...

journal_title：Annals of biomedical engineering

authors： Dunkman AA,Buckley MR,Mienaltowski MJ,Adams SM,Thomas SJ,Satchell L,Kumar A,Pathmanathan L,Beason DP,Iozzo RV,Birk DE,Soslowsky LJ

更新日期：2014-03-01 00:00:00

abstract：:Cell migration paths of mammary epithelial cells (expressing different versions of the promigratory tyrosine kinase receptor Her2/Neu) were analyzed within a bimodal framework that is a generalization of the run-and-tumble description applicable to bacterial migration. The mammalian cell trajectories were segregated i...

journal_title：Annals of biomedical engineering

authors： Potdar AA,Lu J,Jeon J,Weaver AM,Cummings PT

更新日期：2009-01-01 00:00:00

abstract：:Cell migration is a fundamental process that is crucial to a variety of physiological events. While traditional approaches have focused on two-dimensional (2D) systems, recent efforts have shifted to studying migration in three-dimensional (3D) matrices. A major distinction that has emerged is the increased importance...

journal_title：Annals of biomedical engineering

authors： Harjanto D,Zaman MH

更新日期：2010-05-01 00:00:00

abstract：:Auscultation is an important diagnostic indicator for cardiovascular analysis. Heart sound classification and analysis play an important role in the auscultative diagnosis. This study uses a combination of Mel-frequency cepstral coefficient (MFCC) and hidden Markov model (HMM) to efficiently extract the features for p...

journal_title：Annals of biomedical engineering

authors： Wang P,Lim CS,Chauhan S,Foo JY,Anantharaman V

更新日期：2007-03-01 00:00:00

abstract：:User preferences need to be taken into account in order to be able to design devices that will gain acceptance both in a clinical and home setting. Sensor systems become redundant if patients or clinicians do not want to work with them. The aim of this systematic review was to determine both patients' and clinicians' ...

journal_title：Annals of biomedical engineering

authors： Bergmann JH,McGregor AH

更新日期：2011-09-01 00:00:00

abstract：:Radiation applied for therapy and diagnostics damages molecular/atomic couples of biotissues, bones being among them. As a result, electron peculiarities and mechanical behavior of the latter are altered. Correlation between strength of the irradiated bone and its electron features explored due to photo- and exoelectr...

journal_title：Annals of biomedical engineering

authors： Dekhtyar Y

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:We present a fundamental theoretical framework for analysis of energy dissipation in any component of the circulatory system and formulate the full energy budget for both venous and arterial circulations. New indices allowing disease-specific subject-to-subject comparisons and disease-to-disease hemodynamic ...

journal_title：Annals of biomedical engineering

authors： Dasi LP,Pekkan K,de Zelicourt D,Sundareswaran KS,Krishnankutty R,Delnido PJ,Yoganathan AP

更新日期：2009-04-01 00:00:00

abstract：:The blood-brain barrier (BBB) is a major obstacle for drug delivery to the brain. To seek for in vitro BBB models that are more accessible than animals for investigating drug transport across the BBB, we compared four in vitro cultured cell models: endothelial monoculture (bEnd3 cell line), coculture of bEnd3 and prim...

journal_title：Annals of biomedical engineering

authors： Li G,Simon MJ,Cancel LM,Shi ZD,Ji X,Tarbell JM,Morrison B 3rd,Fu BM

更新日期：2010-08-01 00:00:00

abstract：:This article presents a computer-aided detection system for capsule endoscopy (CE) images using contourlet-based color textural features to recognize tumors in the digestive tract. As tumor exhibits rich information in color texture, a novel color texture feature based on contourlet transform is proposed to describe c...

journal_title：Annals of biomedical engineering

authors： Li B,Meng MQ

更新日期：2011-12-01 00:00:00

abstract：:We propose a multifrequency energy transmission scheme for annular phased arrays in deep-body hyperthermia. The problem of frequency dependent resonance effects reported in hyperthermia phantom calibration studies, leading to skewed energy deposition patterns and unwanted energy maxima (hot spots), is addressed by com...

journal_title：Annals of biomedical engineering

authors： Jacobsen S,Melandsø F

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to test the differentiative effects of osteoblasts after treatment with a static magnetic field (SMF). MG63 osteoblast-like cells were exposed to a 0.4-T SMF. The differentiation markers were assessed by observing the changes in alkaline phosphatase activity and electron microscopy images. Me...

journal_title：Annals of biomedical engineering

authors： Chiu KH,Ou KL,Lee SY,Lin CT,Chang WJ,Chen CC,Huang HM

更新日期：2007-11-01 00:00:00

abstract：:Normalized maximal ventricular power (nPWRmax) is an index of cardiac function which measures the innate blood pumping ability, or contractility, of the left ventricle (LV), and its noninvasive assessment could prove useful in a variety of patients. nPWRmax is defined as the maximum instantaneous product of LV pressur...

journal_title：Annals of biomedical engineering

authors： Setser RM,Sayre K,Flacke S,Chia J,Lunn K,Lorenz CH

更新日期：2001-11-01 00:00:00

abstract：:The long held assumption that sustained drug elution from stent coatings over weeks to months is imperative for clinical efficacy has limited the choice for stent coating materials. We developed and evaluated an omega-3 fatty acid (O3FA) based stent coating that is 85% absorbed and elutes 97% of its Sirolimus analog (...

journal_title：Annals of biomedical engineering

authors： Artzi N,Tzafriri AR,Faucher KM,Moodie G,Albergo T,Conroy S,Corbeil S,Martakos P,Virmani R,Edelman ER

更新日期：2016-02-01 00:00:00

abstract：:Statistical methods are increasingly used in biomechanics for studying bone geometry, bone density distribution and function in the population. However, relating population-based bone variation to strain during activity is computationally challenging. Here, we describe a new method for calculating strain in a populati...

journal_title：Annals of biomedical engineering

authors： Ziaeipoor H,Taylor M,Martelli S

更新日期：2020-06-01 00:00:00

abstract：:In this work, we propose an analog electrical model of the coronary circulation for patients with obstructive disease undergoing revascularization. In this clinical situation, the collateral circulation to the occluded artery is difficult to ascertain via preoperative measurements and well-developed collaterals might ...

journal_title：Annals of biomedical engineering

authors： Maasrani M,Verhoye JP,Corbineau H,Drochon A

更新日期：2008-07-01 00:00:00

abstract：:A numerical single path model of respiratory gas exchange with distributed alveolar gas sources was used to estimate the anatomical changes in small peripheral airways such as occur in chronic obstructive pulmonary diseases (COPD). A previous sensitivity analysis of the single path model showed that decreasing total a...

journal_title：Annals of biomedical engineering

authors： Schwardt JD,Neufeld GR,Baumgardner JE,Scherer PW

更新日期：1994-05-01 00:00:00

abstract：:A cable model is formulated to estimate the spatial distribution of intracellular electric potential and current, from the cement line to the lumen of an osteon, as the frequency of the loading and the conductance of the gap junction are altered. The model predicts that the characteristic diffusion time for the spread...

journal_title：Annals of biomedical engineering

authors： Zhang D,Cowin SC,Weinbaum S

更新日期：1997-03-01 00:00:00