Analysis of equine humoral immune responses to the transmembrane envelope glycoprotein (gp45) of equine infectious anemia virus.

abstract：:An in vitro poliovirus RNA-synthesizing system derived from a crude membrane fraction of infected HeLa cells was used to analyze the mechanism of initiation of poliovirus plus-strand RNA synthesis. This system contains an activity that synthesizes the nucleotidyl proteins VPg-pU and VPg-pUpU. These molecules represent...

journal_title：Journal of virology

authors： Takeda N,Kuhn RJ,Yang CF,Takegami T,Wimmer E

更新日期：1986-10-01 00:00:00

abstract：:Viral interference studies have demonstrated the existence of four distinct murine leukemia virus (MuLV) receptors on NIH 3T3 mouse cells. The four viral interference groups are ecotropic MuLV; mink cell focus inducing virus (MCF); amphotropic MuLV; and 10A1, a recombinant derivative of amphotropic MuLV that uses a un...

journal_title：Journal of virology

authors： Ott D,Friedrich R,Rein A

更新日期：1990-02-01 00:00:00

abstract：:Aphid transmission of poleroviruses is highly specific, but the viral determinants governing this specificity are unknown. We used a gene exchange strategy between two poleroviruses with different vectors, Beet western yellows virus (BWYV) and Cucurbit aphid-borne yellows virus (CABYV), to analyze the role of the majo...

journal_title：Journal of virology

authors： Brault V,Périgon S,Reinbold C,Erdinger M,Scheidecker D,Herrbach E,Richards K,Ziegler-Graff V

更新日期：2005-08-01 00:00:00

abstract：:Historically, coronaviruses were predominantly associated with mild upper respiratory disease in humans. More recently, three novel coronaviruses associated with severe human respiratory disease were found, including (i) the severe acute respiratory syndrome coronavirus, associated with a significant atypical pneumoni...

journal_title：Journal of virology

authors： Donaldson EF,Yount B,Sims AC,Burkett S,Pickles RJ,Baric RS

更新日期：2008-12-01 00:00:00

abstract：:By using temperature-sensitive (ts) and suppressor-sensitive (sus) mutants, 11 essential genes have been identified in phage phi105. The order of the genes has been established in two- and three-factor crosses. The genes can be arranged in a linear order; this order is identical in the vegetative phage and in the prop...

journal_title：Journal of virology

authors： Armentrout RW,Rutberg L

更新日期：1970-12-01 00:00:00

abstract：:We recently found that a human T-cell leukemia virus type 1-infected cell line, MT-2, could support the replication of hepatitis C virus (HCV) (N. Kato, T. Nakazawa, T. Mizutani, and K. Shimotohno, Biochem. Biophys. Res. Commun. 206:863-869, 1995). In order to develop a culture system in which HCV replicates more effi...

journal_title：Journal of virology

authors： Mizutani T,Kato N,Saito S,Ikeda M,Sugiyama K,Shimotohno K

更新日期：1996-10-01 00:00:00

abstract：:A strategy involving polymerase chain reaction amplification of cDNAs was designed to study the expression of the hamster polyomavirus (HaPV) early region in HaPV-transformed rat fibroblasts, productively HaPV-infected cells, and HaPV-induced lymphoma. We identified three mRNAs resulting from alternative splicing of o...

journal_title：Journal of virology

authors： Goutebroze L,Feunteun J

更新日期：1992-04-01 00:00:00

abstract：:The expression strategy of parvoviruses of the Densovirus genus has as yet not been reported. Clones were obtained from the densonucleosis virus of Galleria mellonella (GmDNV) that yielded infectious virus upon transfection into LD652 cells. Its genome was found to be the longest (6,039 nucleotides [nt]), with the lar...

journal_title：Journal of virology

authors： Tijssen P,Li Y,El-Far M,Szelei J,Letarte M,Zádori Z

更新日期：2003-10-01 00:00:00

abstract：:Boid inclusion body disease (BIBD) is a transmissible viral disease of captive snakes that causes severe losses in snake collections worldwide. It is caused by reptarenavirus infection, which can persist over several years without overt signs but is generally associated with the eventual death of the affected snakes. ...

journal_title：Journal of virology

authors： Argenta FF,Hepojoki J,Smura T,Szirovicza L,Hammerschmitt ME,Driemeier D,Kipar A,Hetzel U

更新日期：2020-05-18 00:00:00

abstract：:A total of 51 restriction sites were recognized within the BK virus genome by the combination of 10 different restriction endonucleases. These sites were mapped and oriented relative to one another as well as to the five fragments generated by the digestion of BK virus DNA with HindIII and EcoRI. The result was a comp...

journal_title：Journal of virology

authors： Freund J,di Mayorca G,Subramanian KN

更新日期：1979-03-01 00:00:00

abstract：UNLABELLED:The disease mechanisms associated with onset and secondary effects of rotavirus (RV) diarrhea remain to be determined and may not be identical. In this study, we investigated whether onset of RV diarrhea is associated with increased intestinal permeability and/or motility. To study the transit time, fluoresc...

journal_title：Journal of virology

authors： Istrate C,Hagbom M,Vikström E,Magnusson KE,Svensson L

更新日期：2014-03-01 00:00:00

abstract：:A human lymphoid cell line (F172-D8) excreting a human immunodeficiency virus type 1 (HIV-1) anti-gp41 monoclonal antibody was used to construct a plasmid containing the cDNA of the single-chain variable fragment (scFvD8) corresponding to this antibody. A stable human osteosarcoma cell line was obtained which expresse...

journal_title：Journal of virology

authors： Legastelois I,Desgranges C

更新日期：2000-06-01 00:00:00

abstract：:Clones of virogenic simian virus 40 (SV40)-transformed hamster kidney cells were exposed to medium deficient in the essential amino acids leucine, arginine, or methionine. Infectious virus was induced after deprivation periods of from 24 to 32 hr. The highest yields of infectious SV40 were obtained from cultures depri...

journal_title：Journal of virology

authors： Kaplan JC,Wilbert SM,Black PH

更新日期：1972-03-01 00:00:00

abstract：:The sensitivity of highly purified human fibroblast interferon and partially purified human leukocyte interferon to several proteolytic and glycolytic enzymes was determined with respect to antiviral activity, isoelectric point, molecular weight, and thermal stability. Leucine aminopeptidase altered the distribution o...

journal_title：Journal of virology

authors： Otto MJ,Sedmak JJ,Grossberg SE

更新日期：1980-08-01 00:00:00

abstract：:The mammalian tripartite motif protein, TRIM5α, recognizes retroviral capsids entering the cytoplasm and blocks virus infection. Depending on the particular TRIM5α protein and retrovirus, complete disruption of the TRIM5α RING domain decreases virus-restricting activity to various degrees. TRIM5α exhibits RING domain-...

journal_title：Journal of virology

authors： Kim J,Tipper C,Sodroski J

更新日期：2011-08-01 00:00:00

abstract：:In vitro transcription by vesicular stomatitis virus nucleocapsids is inhibited by enzymatic dephosphorylation of the NS protein. We provide evidence that specific, partial dephosphorylation of NS molecules is the only detectable change in nucleocapsids treated with bacterial alkaline phosphatase under conditions that...

journal_title：Journal of virology

authors： Hsu CH,Morgan EM,Kingsbury DW

更新日期：1982-07-01 00:00:00

abstract：:Recognition of virus infections by pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs), retinoic acid-inducible gene I (RIG-I), and melanoma differentiation associated gene 5 (MDA5), activates signaling pathways, leading to the induction of inflammatory cytokines that limit viral replication. To d...

journal_title：Journal of virology

authors： Guo H,Jiang D,Ma D,Chang J,Dougherty AM,Cuconati A,Block TM,Guo JT

更新日期：2009-01-01 00:00:00

abstract：:Assembly and maturation of retroviral particles requires the aggregation and controlled proteolytic cleavage of polyprotein core precursors by a precursor-encoded protease (PR). Active, mature retroviral PR is a dimer, and the accumulation of precursors at sites of assembly may facilitate subunit interaction and subse...

journal_title：Journal of virology

authors： Burstein H,Bizub D,Skalka AM

更新日期：1991-11-01 00:00:00

abstract：:HBI is a recombinant avian retrovirus with novel pathogenic properties that was derived from the myc-containing virus MC29. In contrast to MC29, which causes endotheliomas in chickens, HBI induces lymphoid tumors. The results of molecular cloning and nucleotide sequencing of HBI reported here show that the virus conta...

journal_title：Journal of virology

authors： Smith DR,Vennstrom B,Hayman MJ,Enrietto PJ

更新日期：1985-12-01 00:00:00

abstract：UNLABELLED:Coronaviruses (CoVs) are unique in encoding a 3'→5' exoribonuclease within nonstructural protein 14 (nsp14-ExoN) that is required for high-fidelity replication, likely via proofreading. nsp14 associates with the CoV RNA-dependent RNA polymerase (nsp12-RdRp), and nsp14-ExoN activity is enhanced by binding nsp...

journal_title：Journal of virology

authors： Smith EC,Case JB,Blanc H,Isakov O,Shomron N,Vignuzzi M,Denison MR

更新日期：2015-06-01 00:00:00

abstract：:The ability of the gamma(1)34.5 protein to suppress the PKR response plays a crucial role in herpes simplex virus pathogenesis. In this process, the gamma(1)34.5 protein associates with protein phosphatase 1 to form a large complex that dephosphorylates eIF-2alpha and thereby prevents translation shutoff mediated by P...

journal_title：Journal of virology

authors： Jing X,Cerveny M,Yang K,He B

更新日期：2004-07-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) has evolved multiple strategies for suppression of the antiviral response of the infected cell. DNA array technology has revealed that HCMV clearly regulates host gene expression during the course of a productive infection by enhancing, sustaining, or suppressing steady-state levels of cel...

journal_title：Journal of virology

authors： Gealy C,Denson M,Humphreys C,McSharry B,Wilkinson G,Caswell R

更新日期：2005-01-01 00:00:00

abstract：:Relative to wild-type herpes simplex virus type 1 (HSV-1), ICP0-null mutant viruses reactivate inefficiently from explanted, latently infected mouse trigeminal ganglia (TG), indicating that ICP0 is not essential for reactivation but plays a central role in enhancing the efficiency of reactivation. The validity of thes...

journal_title：Journal of virology

authors： Halford WP,Schaffer PA

更新日期：2001-04-01 00:00:00

abstract：:Polypeptides synthesized in Newcastle disease virus (NDV)-infected CHO cells in the absence of glycosylation were characterized. Incorporation of either [3H]mannose of [3H]glucosamine into NDV polypeptides was inhibited to greater than 99% by the antibiotic tunicamycin. Under these conditions, infected cells synthesiz...

journal_title：Journal of virology

authors： Morrison TG,Simpson D

更新日期：1980-10-01 00:00:00

abstract：:Vaccinia virus has a wide host range and infects mammalian cells of many different species. This suggests that the cell surface receptors for vaccinia virus are ubiquitously expressed and highly conserved. Alternatively, different receptors are used for vaccinia virus infection of different cell types. Here we report ...

journal_title：Journal of virology

authors： Chung CS,Hsiao JC,Chang YS,Chang W

更新日期：1998-02-01 00:00:00

abstract：:Nonstructural protein 5B (NS5B) of bovine viral diarrhea virus (BVDV) contains sequence motifs that are predictive of an RNA-dependent RNA polymerase activity. We describe the expression and purification of the BVDV NS5B protein derived from an infectious cDNA clone of BVDV (NADL strain). BVDV NS5B protein was active ...

journal_title：Journal of virology

authors： Zhong W,Gutshall LL,Del Vecchio AM

更新日期：1998-11-01 00:00:00

abstract：:The Vpr protein, encoded by the human immunodeficiency virus type 1 (HIV-1) genome, is one of the nonstructural proteins packaged in large amounts into viral particles. We have previously reported that Vpr associates with the DNA repair enzyme uracil DNA glycosylase (UDG). In this study, we extended these observations...

journal_title：Journal of virology

authors： Willetts KE,Rey F,Agostini I,Navarro JM,Baudat Y,Vigne R,Sire J

更新日期：1999-02-01 00:00:00

abstract：UNLABELLED:Testudinid herpesvirus 3 (TeHV-3) is the causative agent of a lethal disease affecting several tortoise species. The threat that this virus poses to endangered animals is focusing efforts on characterizing its properties, in order to enable the development of prophylactic methods. We have sequenced the genom...

journal_title：Journal of virology

authors： Gandar F,Wilkie GS,Gatherer D,Kerr K,Marlier D,Diez M,Marschang RE,Mast J,Dewals BG,Davison AJ,Vanderplasschen AF

更新日期：2015-11-01 00:00:00

abstract：:The identification of several simian immunodeficiency virus mac251 (SIV(mac251)) cytotoxic T-lymphocyte epitopes recognized by CD8(+) T cells of infected rhesus macaques carrying the Mamu-A*01 molecule and the use of peptide-major histocompatibility complex tetrameric complexes enable the study of the frequency, bread...

journal_title：Journal of virology

authors： Hel Z,Nacsa J,Kelsall B,Tsai WP,Letvin N,Parks RW,Tryniszewska E,Picker L,Lewis MG,Edghill-Smith Y,Moniuszko M,Pal R,Stevceva L,Altman JD,Allen TM,Watkins D,Torres JV,Berzofsky JA,Belyakov IM,Strober W,Franchini G

更新日期：2001-12-01 00:00:00

abstract：:Monoclonal antibodies to varicella-zoster virus were used to study viral glycoproteins by immunoprecipitation and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Based on the viral glycoproteins immunoprecipitated, the five monoclonal antibodies fell into three groups. Two antibodies, 4B7 and 8G9 (group 1),...

journal_title：Journal of virology

authors： Forghani B,Dupuis KW,Schmidt NJ

更新日期：1984-10-01 00:00:00