Abstract:
:Schizophrenia is associated with severe deficits in social functioning. Similar deficits may be present prior to psychosis onset, in childhood and adolescence. If so, then prepsychosis social deficits could provide clues to the development of pathological processes in preschizophrenia children and could potentially improve early identification of the disorder and suggest targets for intervention. Evidence is reviewed from birth cohort, case- control, and familial high-risk studies within distinct periods of development to clarify the nature, timing, and specificity of social deficits in preschizophrenia children and adolescents. The results indicate that poor social functioning does differentiate preschizophrenia children and adolescents from their peers and can be a sensitive and potentially specific predictor of schizophrenia, not just psychopathology in general. Furthermore, age (but not sex) appears to be an important moderator of the strength and specificity of the association between particular social deficits (e.g., externalizing, internalizing) and later schizophrenia. Results are discussed in the context of current developmental theories of timing and pathophysiology of schizophrenia involving hypothalamic- pituitary-adrenal dysregulation. Implications for the early identification and treatment of preschizophrenia individuals are also considered.
journal_name
Psychol Bulljournal_title
Psychological bulletinauthors
Tarbox SI,Pogue-Geile MFdoi
10.1037/0033-2909.34.4.561subject
Has Abstractpub_date
2008-07-01 00:00:00pages
561-83issue
4eissn
0033-2909issn
1939-1455pii
2008-08177-007journal_volume
134pub_type
杂志文章,评审abstract::There are both monotonic and rhythmic factors in the patterns of change seen in physiological, psychological, and performance variables during sleep deprivation. These monotonic and rhythmic factors can be orthogonal, or they may interact with each other, with various task variables, or both. The importance of separat...
journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/0033-2909.109.3.411
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journal_title:Psychological bulletin
pub_type: 杂志文章,meta分析,评审
doi:10.1037/bul0000025
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/0033-2909.126.1.55
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journal_title:Psychological bulletin
pub_type: 评论,杂志文章
doi:10.1037/a0019215
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journal_title:Psychological bulletin
pub_type: 杂志文章,meta分析,评审
doi:10.1037/bul0000084
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journal_title:Psychological bulletin
pub_type: 杂志文章,meta分析,评审
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/bul0000042
更新日期:2016-06-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 评论,杂志文章
doi:10.1037/a0028541
更新日期:2012-09-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,meta分析
doi:10.1037/0033-2909.126.5.703
更新日期:2000-09-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/0033-2909.129.2.216
更新日期:2003-03-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/0033-2909.129.4.545
更新日期:2003-07-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:
更新日期:1995-05-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,meta分析
doi:10.1037/0033-2909.131.5.785
更新日期:2005-09-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/bul0000077
更新日期:2016-12-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,meta分析
doi:10.1037/0033-2909.124.1.22
更新日期:1998-07-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/bul0000089
更新日期:2017-03-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 评论,杂志文章
doi:10.1037/a0030246
更新日期:2013-01-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,meta分析
doi:10.1037/0033-2909.124.3.283
更新日期:1998-11-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/0033-2909.126.4.475
更新日期:2000-07-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/a0028566
更新日期:2013-01-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/a0030010
更新日期:2013-05-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章
doi:10.1037/0033-2909.125.5.507
更新日期:1999-09-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 评论,杂志文章
doi:10.1037/a0034453
更新日期:2013-11-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 评论,杂志文章
doi:10.1037/a0024843
更新日期:2011-09-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/0033-2909.108.1.109
更新日期:1990-07-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章
doi:10.1037/0033-2909.132.2.151
更新日期:2006-03-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/0033-2909.116.2.195
更新日期:1994-09-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章
doi:10.1037/0033-2909.128.6.978
更新日期:2002-11-01 00:00:00
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journal_title:Psychological bulletin
pub_type: 杂志文章,评审
doi:10.1037/0033-2909.114.1.80
更新日期:1993-07-01 00:00:00