Development of social functioning in preschizophrenia children and adolescents: a systematic review.

Abstract:

:Schizophrenia is associated with severe deficits in social functioning. Similar deficits may be present prior to psychosis onset, in childhood and adolescence. If so, then prepsychosis social deficits could provide clues to the development of pathological processes in preschizophrenia children and could potentially improve early identification of the disorder and suggest targets for intervention. Evidence is reviewed from birth cohort, case- control, and familial high-risk studies within distinct periods of development to clarify the nature, timing, and specificity of social deficits in preschizophrenia children and adolescents. The results indicate that poor social functioning does differentiate preschizophrenia children and adolescents from their peers and can be a sensitive and potentially specific predictor of schizophrenia, not just psychopathology in general. Furthermore, age (but not sex) appears to be an important moderator of the strength and specificity of the association between particular social deficits (e.g., externalizing, internalizing) and later schizophrenia. Results are discussed in the context of current developmental theories of timing and pathophysiology of schizophrenia involving hypothalamic- pituitary-adrenal dysregulation. Implications for the early identification and treatment of preschizophrenia individuals are also considered.

journal_name

Psychol Bull

journal_title

Psychological bulletin

authors

Tarbox SI,Pogue-Geile MF

doi

10.1037/0033-2909.34.4.561

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

561-83

issue

4

eissn

0033-2909

issn

1939-1455

pii

2008-08177-007

journal_volume

134

pub_type

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