Herpes simplex virus type 2: epidemiology and management options in developing countries.

Abstract:

:Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical disease and the occurrence of asymptomatic shedding. The lack of easy, affordable diagnostic methods and specific antiviral treatment in countries with low and middle income is of great concern, given the ability of GUD to enhance HIV transmission and acquisition. With rising HSV2 prevalence contributing to an increase in the proportion of GUD attributed to genital herpes in high-HIV prevalence settings, a safe and effective HSV vaccine is urgently needed. Meanwhile, multifaceted interventions are required to improve recognition of genital herpes, to prevent its spread and also to prevent its potential to promote HIV transmission in developing countries.

journal_name

Postgrad Med J

authors

Paz-Bailey G,Ramaswamy M,Hawkes SJ,Geretti AM

doi

10.1136/sti.2006.020966

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

299-306

issue

992

eissn

0032-5473

issn

1469-0756

pii

84/992/299

journal_volume

84

pub_type

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