Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects.

Abstract:

:Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia. This review summarises the classification and clinical and therapeutic aspects of cryoglobulinaemic vasculitis and glomerulonephritis.

journal_name

Postgrad Med J

authors

Braun GS,Horster S,Wagner KS,Ihrler S,Schmid H

doi

10.1136/pgmj.2006.046078

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

87-94

issue

976

eissn

0032-5473

issn

1469-0756

pii

83/976/87

journal_volume

83

pub_type

杂志文章,评审
  • Fever, hepatosplenomegaly and pancytopenia in a patient living in the Mediterranean region.

    abstract::A 24 year old woman living in the Mediterranean region of Turkey present with a three-month history of weight loss and irregular fever that was peaking at 40 degrees C with shivering. No definite aetiology could be identified in a local hospital. A bacterial infection had been suspected, but antibiotic therapy, at fir...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.74.870.237

    authors: Büyükaşik Y,Ileri NS,Haznedaroğlu IC,Demiroğlu H,Dündar S

    更新日期:1998-04-01 00:00:00

  • Carcinoma of the duodenum.

    abstract::We report two patients with primary adenocarcinoma of the duodenum who underwent successful pancreatico-duodenectomy (modified Whipple operation). One patient died from an unrelated cause three years following surgery whilst the other remains well and clinically free of disease 3 years after resection. An aggressive s...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.63.744.907

    authors: Carragher A,Russell C

    更新日期:1987-10-01 00:00:00

  • Extreme metabolic alkalosis with fludrocortisone therapy.

    abstract::We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement. Some dangers of this therapy and necessary precautions ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.59.694.506

    authors: Burns A,Brown TM,Semple P

    更新日期:1983-08-01 00:00:00

  • Republished review: Tourette's syndrome and other tic disorders.

    abstract::Tourette's syndrome is a neuropsychiatric disorder characterised by motor and phonic tics. Although tics are common in children, only about 1% of those affected meet the criteria for Tourette's syndrome, and many are not disabled by it. Associated problems such as attention deficit hyperactivity disorder and obsessive...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2010.223685rep

    authors: Rickards H

    更新日期:2011-02-01 00:00:00

  • Hypomagnesaemia and hypocalcaemia in a patient with ovarian carcinoma.

    abstract::A patient with disseminated ovarian carcinoma presented with symptoms of hypocalcaemia secondary to hypomagnesaemia. The low serum magnesium (0.4 mmol/l) appeared to be due to renal leakage with no evidence of ureteric obstruction or hydronephrosis on intravenous urogram. Parathyroid hormone activity (serum levels and...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.69.813.583

    authors: Leese GP,Jung RT,Browning MC

    更新日期:1993-07-01 00:00:00

  • What's in a smile? A review of the benefits of the clinician's smile.

    abstract::For millennia, the smile has been recognised as a powerful communication device, offering benefits to both giver and receiver with few drawbacks. A sign of compassion, empathy and friendliness, smiling can benefit healthcare professionals and their patients, helping to build a relationship of trust. But beware the fal...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/postgradmedj-2018-136286

    authors: Beamish AJ,Foster JJ,Edwards H,Olbers T

    更新日期:2019-02-01 00:00:00

  • Tuberculous perforation of the small bowel.

    abstract::Small bowel perforation occurs in up to 2 percent of patients with abdominal tuberculous. Patients present with an acute abdomen. Resection of the diseased segment and 18 months treatment with anti-tuberculosis drugs is recommended. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.713.251

    authors: Aston NO,de Costa AM

    更新日期:1985-03-01 00:00:00

  • Vasodilator therapy of dilated cardiomyopathy.

    abstract::Vasoconstriction increases impedance to ventricular ejection and impairs the performance of the dilated myopathic heart. Vasodilator drug therapy by reducing vascular resistance, increasing vascular compliance and increasing vascular capacitance improves cardiac function and relieves the signs and symptoms of congesti...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.728.599

    authors: Cohn JN

    更新日期:1986-06-01 00:00:00

  • Adverse reaction to disopyramide.

    abstract::A case is reported where the use of i.v. disopyramide for a supraventricular tachycardia resulted in a more serious ventricular dysrhythmia giving hypotension and this probably contributed to the development of a myocardial infarction. Attention is drawn to the possible risk. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.55.646.570

    authors: Dibble JB,Webster NR

    更新日期:1979-09-01 00:00:00

  • To bed or not to bed: the sleep question?

    abstract:BACKGROUND:Sleep deprivation and fatigue from long-shift work impacts doctors' personal safety, inhibits cognitive performance and risks clinical error. The aim of this study was to assess the sleep quality of surgical trainees participating in European Working Time Directive-compliant training rotations within a UK de...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2018-135795

    authors: Brown C,Abdelrahman T,Lewis W,Pollitt J,Egan R,members of the Welsh Surgical Research Initiative.

    更新日期:2020-09-01 00:00:00

  • Ventricular fibrillation during electrical cardioversion of pre-excited atrial fibrillation.

    abstract::The Wolff-Parkinson-White syndrome can rarely present with pre-excited atrial fibrillation. In this condition the short refractory period of the accessory pathway can lead to rapid atrioventricular conduction. There is then a danger that at high heart rates the irregular broad complex tachycardia that results can dete...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pmj.79.931.297

    authors: Adlam D,Azeem T

    更新日期:2003-05-01 00:00:00

  • Longitudinal study of Chinese patients with pernicious anaemia.

    abstract:BACKGROUND:The survival of whites who have been treated for pernicious anaemia (PA) is unaffected, apart from incurring a greater risk of gastric cancers. The long term outcome of PA in Chinese is unknown. METHODS:A hospital based prospective longitudinal study of Chinese PA patients was conducted. Patients with known...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2007.067421

    authors: Chan JC,Liu HS,Kho BC,Lau TK,Li VL,Chan FH,Leong IS,Pang HK,Lee CK,Liang YS

    更新日期:2008-12-01 00:00:00

  • Elevated serum parathyroid hormone related protein and 1,25-dihydroxycholecalciferol in hypercalcaemia associated with adult T-cell leukaemia-lymphoma.

    abstract::Hypercalcaemia occurs in up to 80% of patients with adult T-cell leukaemia-lymphoma (ATLL) associated with human T-cell leukaemia virus-1 infection. Elevated serum levels of 1,25-dihydroxycholecalciferol, implicated in the pathogenesis of hypercalcaemia in lymphoma, and of parathyroid hormone-related protein (PTHrP), ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.68.803.753

    authors: Johnston SR,Hammond PJ

    更新日期:1992-09-01 00:00:00

  • Congenital absence of the intrahepatic segment of the inferior vena cava with azygos continuation presenting as a mediastinal mass.

    abstract::A child with the isolated anomaly of azygos continuation of the inferior vena cava is presented. The interest of this abnormality lies in its detection as a mediastinal mass on the chest radiograph. Computed tomography with intravenous contrast enhancement is the method of choice to diagnose this venous anomaly. Aware...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.65.762.253

    authors: Beedie RJ,Yeo W,Morcos SK

    更新日期:1989-04-01 00:00:00

  • Drain in laparoscopic cholecystectomy in acute calculous cholecystitis: a randomised controlled study.

    abstract:BACKGROUND:There is paucity of evidence regarding the role of drain in laparoscopic cholecystectomy (LC) in acute calculous cholecystitis (ACC), and surgeons have placed the drains based on their experiences, not on evidence-based guidelines. This study aims to assess the value of drain in LC for ACC in a randomised co...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2019-136828

    authors: Valappil MV,Gulati S,Chhabra M,Mandal A,Bakshi S,Bhattacharyya A,Ghatak S

    更新日期:2020-10-01 00:00:00

  • Cerebellar disturbance in psittacosis.

    abstract::A previously fit man developed psittacosis with marked cerebellar symptoms and signs. He was febrile but not confused, and he responded rapidly to treatment with erythromycin. Even if respiratory symptoms are minimal, psittacosis and other atypical pneumonias should be considered in any patient presenting with fever a...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.64.751.382

    authors: Shee CD

    更新日期:1988-05-01 00:00:00

  • Ethnic minorities, health provision and the 1976 Race Relations Act.

    abstract::The present anti-racial discrimination legislation in the United Kingdom is embodied in the 1976 Race Relations Act. In essence this Act attempts to avoid any form of direct or indirect discrimination on the basis of racial or ethnic origin. However, health professionals are acutely aware that there are important raci...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.66.782.1043

    authors: Bedi R,MacEwen M

    更新日期:1990-12-01 00:00:00

  • The Mirizzi syndrome.

    abstract::The Mirizzi syndrome is an unusual presentation of gallstones which occurs when a gallstone becomes impacted in either Hartmann's pouch of the gallbladder or the cystic duct, causing obstruction of the common hepatic duct by extrinsic compression. The diagnosis of this syndrome is of importance because surgery in its ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.73.862.487

    authors: Pemberton M,Wells AD

    更新日期:1997-08-01 00:00:00

  • Lessons from falling coronary heart disease mortality in the United States.

    abstract::The marked decline in coronary heart disease mortality in the United States since the late 1960s is most likely due in large part to successful efforts at primary prevention, attributable in turn to improved eating habits, better control of blood pressure and a reduction in smoking. Another part of the decline can pro...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.60.699.15

    authors: Epstein FH

    更新日期:1984-01-01 00:00:00

  • Liver transplantation for hepatitis C virus related liver disease.

    abstract::Liver transplantation is a useful treatment for end stage liver disease of all aetiologies but recurrent disease presents an ongoing challenge, particularly for hepatitis C virus (HCV) where recurrence is almost universal. Immunosuppression is needed for all patients after transplantation and should be tailored to the...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2005.034082

    authors: Gee I,Alexander G

    更新日期:2005-12-01 00:00:00

  • A minimalist electronic health record-based intervention to reduce standing lab utilisation.

    abstract:BACKGROUND:Repetitive laboratory testing in stable patients is low-value care. Electronic health record (EHR)-based interventions are easy to disseminate but can be restrictive. OBJECTIVE:To evaluate the effect of a minimally restrictive EHR-based intervention on utilisation. SETTING:One year before and after interve...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2019-136992

    authors: Chin KK,Krishnamurthy A,Zubair T,Ramaswamy T,Hom J,Maggio P,Shieh L

    更新日期:2021-02-01 00:00:00

  • Florid granulomatous reaction in a seminoma.

    abstract::A case of seminoma of the testis complicated by an extensive granulomatous reaction is reported. This reaction was so florid that a benign condition was initially considered until further material for histology was examined and the correct diagnosis made. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.59.691.334

    authors: Pickard WR,Clark AH,Abel BJ

    更新日期:1983-05-01 00:00:00

  • Villous adenoma of the rectum with electrolyte depletion, diabetes and hypogonadism.

    abstract::The case of a woman with a large benign villous papilloma of the rectum, presenting with sodium and water depletion and later complicated by persistent hypokalaemia, is described. The patient also suffered from primary hypogonadism and diabetes. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.41.474.186

    authors: Bamford JK,Galbraith HJ,Pender BW

    更新日期:1965-04-01 00:00:00

  • Tobacco modalities used and outcome in patients with acute coronary syndrome: an observational report.

    abstract:AIM:The authors evaluated the prevalence and effect of the various tobacco use modalities among patients presenting with acute coronary syndrome (ACS) and compared them with non-tobacco and ex-tobacco users. METHODS:An analysis of the 2nd Gulf Registry of Acute Coronary Events conducted between October 2008 and June 2...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,多中心研究

    doi:10.1136/postgradmedj-2011-130178

    authors: Al Suwaidi J,Al Habib K,Singh R,Hersi A,Al Nemer K,Asaad N,Al Saif S,Al-Motarreb A,Almahmeed W,Sulaiman K,Amin H,Al-Lawati J,Al Bustani N,Al-Sagheer NQ,Ali WM

    更新日期:2012-10-01 00:00:00

  • Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome?

    abstract::Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised as a major public health burden. Large-scale epidemiological studies have demonstrated an independent relationship between OSAS and various cardiovascular disorders. The pathogenesis of cardiovascular complications in OSAS is not ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/thx.2008.105577

    authors: Ryan S,Taylor CT,McNicholas WT

    更新日期:2009-12-01 00:00:00

  • Neurohormonal responses to antihypertensive treatment with captopril or hydrochlorothiazide.

    abstract::In order to assess the neurohormonal responses to oral administration of two drugs with different antihypertensive mechanisms, and their implications for long-term efficacy, we studied the changes in plasma renin activity, aldosterone, catecholamines and blood pressure after two cross-over periods of treatment with ca...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rabinad E,Gaya J,Rivera F,Ingelmo M,Balcells A

    更新日期:1986-01-01 00:00:00

  • Motor neurone disease.

    abstract::Motor neurone disease (MND), or amyotrophic lateral sclerosis (ALS), is a neurodegenerative disorder of unknown aetiology. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Confirming the diagnosis may initially be difficult until the full clinical features ar...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pmj.78.923.513

    authors: Talbot K

    更新日期:2002-09-01 00:00:00

  • Early prediction of the outcome of a paracetamol overdose based on an analysis of 163 patients.

    abstract::Clinical and biochemical data obtained from 163 patients who had taken an overdose of paracetamol were examined to determine which factors or measurements were of value in predicting the severity of ensuing liver damage early after ingestion of tablets. Although the overall severity of hepatic necrosis was found to in...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.53.619.243

    authors: Gazzard BG,Widdop B,Davis M,Hughes RD,Goulding R,Williams R

    更新日期:1977-05-01 00:00:00

  • Measurement of the effects of a single dose of prazosin on the cerebral blood flow in hypertensive patients.

    abstract::It was considered that the first dose reaction occurring with prazosin may have been due either to hypotension or to a specific reduction in cerebral blood flow. The development of a quantitative non-invasion nuclear medicine technique for cerebral flow has now made it possible to investigate the effects of prazosin o...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/pgmj.56.662.818

    authors: Rutland MD,Lee TY,Nimmon CC,Granowska M,Britton KE

    更新日期:1980-12-01 00:00:00

  • Severe acute respiratory syndrome (SARS): epidemiology and clinical features.

    abstract::Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease with a significant morbidity and mortality. The major clinical features include persistent fever, chills/rigor, myalgia, malaise, dry cough, headache, and dyspnoea. Older subjects may present without the typical febrile response. Common lab...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2004.020263

    authors: Hui DS,Chan MC,Wu AK,Ng PC

    更新日期:2004-07-01 00:00:00