Adverse reaction to disopyramide.

abstract：:The anticoagulant agents heparin and warfarin were introduced before the era of randomised clinical trials. As a result, the indications, dosages and monitoring techniques of these drugs have undergone re-evaluation in multiple clinical trials in the past years. Low molecular weight heparin has been developed, which h...

journal_title：Postgraduate medical journal

authors： Toh CH

更新日期：1997-05-01 00:00:00

abstract：:Two patients with severe dothiepin intoxication are described. The management of these cases is discussed and we draw attention to the prolonged elimination half-life of dothiepin and its metabolites, and the implication for treatment. ...

journal_title：Postgraduate medical journal

authors： Bloodworth L,Wilson A,Collins P,Rainford DJ

更新日期：1984-06-01 00:00:00

abstract：:Two young patients with sickle cell trait (AS haemaglobinopathy) and ischaemic stroke are reported. The stroke involved the internal carotid artery territory in one and the brainstem in the other. A review of the literature is presented to suggest that the association of sickle cell trait and cerebral infarction is mo...

journal_title：Postgraduate medical journal

authors： Radhakrishnan K,Thacker AK,Maloo JC,el-Mangoush MA

更新日期：1990-12-01 00:00:00

abstract：PURPOSE:Workplace-based assessments (WBAs) were originally intended to inform learning and development by structuring effective observation-based feedback. The success of this innovation has not yet been established due in part to the widely varied tools, implementation strategies and research approaches. Using a conce...

journal_title：Postgraduate medical journal

authors： Barrett A,Galvin R,Scherpbier AJ,Teunissen PW,O'Shaughnessy A,Horgan M

更新日期：2017-03-01 00:00:00

abstract：:Exacerbations of chronic obstructive pulmonary disease impose a considerable burden of morbidity, mortality, and health care cost. Management guidelines outlining best practice, based largely on consensus expert opinion, were produced by a number of organisations during the last decade. Current interest in the field i...

journal_title：Postgraduate medical journal

authors： Hurst JR,Wedzicha JA

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:How medical students learn and develop the characteristics associated with good teaching in medicine is not well known. Information about this process can improve the academic preparation of medical students for teaching responsibilities. The purpose of this study was to determine how different experiences cont...

journal_title：Postgraduate medical journal

authors： Henry BW,Haworth JG,Hering P

更新日期：2006-09-01 00:00:00

abstract：:Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia...

journal_title：Postgraduate medical journal

authors： Braun GS,Horster S,Wagner KS,Ihrler S,Schmid H

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF THE STUDY:To explore which factors increase the likelihood of being deemed appointable to core anaesthesia training in the UK and whether those factors subsequently predict performance in postgraduate training. STUDY DESIGN:Observational study linking UK medical specialty recruitment data with postgraduate ...

journal_title：Postgraduate medical journal

authors： Aslet M,Paton LW,Gale T,Tiffin PA

更新日期：2020-01-01 00:00:00

abstract：:Learning curves graphically represent the relationship between learning effort and learning outcome. Learning curves are increasingly used in research, the design of randomised controlled trials, the assessment of competency, healthcare education and training programme design. In this review we have outlined the princ...

journal_title：Postgraduate medical journal

authors： Valsamis EM,Chouari T,O'Dowd-Booth C,Rogers B,Ricketts D

更新日期：2018-09-01 00:00:00

abstract：:Fourteen patients suffering from various degrees of bone dysplasia and mental handicap with superimposed neuroses or psychotic episodes are reported. Known biochemical and chromosomal causes are noted. Mental states associated with syndromes and mental malfunctioning or impairment because of skeletal defects or other ...

journal_title：Postgraduate medical journal

authors： Jancar J

更新日期：1977-08-01 00:00:00

abstract：:Coeliac disease is exacerbated by wheat gluten. A review of methods for the purification, identification and quantitation of wheat proteins to investigate coeliac disease is presented. Recent developments including amino acid sequencing and expression of wheat protein peptides in E. coli should permit characterization...

journal_title：Postgraduate medical journal

authors： Ciclitira PJ,Ellis HJ

更新日期：1987-09-01 00:00:00

abstract：:Herniation of a thoracic disc in an acromegalic giant is reported. Degenerative changes in the spine in association with dorsal kyphosis, and the additional strain, resulted in the disc prolapse. ...

journal_title：Postgraduate medical journal

authors： Chhang WH,Sharma BS,Dash RJ,Kak VK

更新日期：1989-07-01 00:00:00

abstract：:The mechanisms of the antinociceptive action of flupirtine, a novel non-opioid analgesic, were investigated in animals. It was found that this effect could be abolished by pre-treatment with reserpine. Furthermore, it could be dose-dependently antagonized by yohimbine and changes in the EEG of the rat observed after a...

journal_title：Postgraduate medical journal

authors： Szelenyi I,Nickel B

更新日期：1987-01-01 00:00:00

abstract：:Parasites in the human breast are uncommon but not rare. Cysticercus and filariasis in fine needle breast aspirates have been documented and their cytomorphology is well characterised. However, the host tissue response to these parasites and the factors responsible for their initiation are not clear. Over a 21 year pe...

journal_title：Postgraduate medical journal

authors： Sahai K,Kapila K,Verma K

更新日期：2002-03-01 00:00:00

abstract：:Little is known about orthostatic blood pressure regulation in acute stroke. We determined postural haemodynamic responses in 40 patients with acute stroke (mild or moderate severity) and 40 non-stroke control in-patients, at two days ('Day 1') and one week ('Week 1') post-admission. Following a 10-minute supine rest ...

journal_title：Postgraduate medical journal

authors： Panayiotou B,Reid J,Fotherby M,Crome P

更新日期：1999-04-01 00:00:00

abstract：:Reports of malignant melanoma involving the heart usually describe metastatic spread of pigmented (melanotic) forms of this tumour. We describe, and illustrate, a patient presenting with features related to cardiac tamponade and intracardiac obstruction. Transthoracic echocardiography initially showed a large mass wit...

journal_title：Postgraduate medical journal

authors： Dubrey S,Grocott-Mason R,Mittal T,Burke M

更新日期：2008-03-01 00:00:00

abstract：:Tobacco smoking contributes to about six million deaths per year and is predicted to increase in the future. Several pharmacological interventions are used for smoking cessation. Trials using nicotine replacement therapy (NRT) in acute coronary syndrome (ACS) showed inconclusive results. Furthermore, three trials usin...

journal_title：Postgraduate medical journal

authors： Chehab OM,Dakik HA

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:To explore the relationship between cognitive impairment and conventional measures of disability in multiple sclerosis (MS), quality of life (QOL) and employment status using the brief international cognitive assessment for multiple sclerosis (BICAMS) in the routine outpatient clinic. METHODS:62 patients wi...

journal_title：Postgraduate medical journal

authors： Campbell J,Rashid W,Cercignani M,Langdon D

更新日期：2017-03-01 00:00:00

abstract：:Three patients with lung carcinoid related Cushing's syndrome (LCRCS) treated at Frenchay Hospital, Bristol between 1984 and 1994 are described. The first patient presented with hyperpigmentation 13 years after bilateral adrenalectomy. The second patient had no recurrence or metastases 14 years after removal of a typi...

journal_title：Postgraduate medical journal

authors： Amer KM,Ibrahim NB,Forrester-Wood CP,Saad RA,Scanlon M

更新日期：2001-07-01 00:00:00

abstract：:Vaginal vein thrombosis in a pregnant woman is reported. This entity should be differentiated from vaginal arteriovenous fistula which may cause severe antepartum, intrapartum and post-partum haemorrhage. The humoral and mechanical factors which favour the occurrence of varicosities and thrombosis are briefly describe...

journal_title：Postgraduate medical journal

authors： Gitstein S,Ballas S,Peyser MR

更新日期：1983-06-01 00:00:00

abstract：PURPOSE OF THE STUDY:This study aims to describe all unsolicited electronic invitations received from potential predatory publishers or fraudulent conferences over a 12-month period following the first publication as a corresponding author of a junior academician. STUDY DESIGN:Unsolicited invitations received at an in...

journal_title：Postgraduate medical journal

authors： Mercier E,Tardif PA,Moore L,Le Sage N,Cameron PA

更新日期：2018-02-01 00:00:00

abstract：:A 56 year old man presented with an atypical chest infection. Remote inferoposterior myocardial infarction was noted on electrocardiography and transthoracic echocardiography. Hepatic failure developed with sudden gross elevation of liver aminotransferases and coagulopathy. No primary hepatic cause could be identified...

journal_title：Postgraduate medical journal

authors： Szawarski P,Sensky PR,Doshi M,Hudson I

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:This explorative study was triggered by the '#hellomynameis' campaign initiated by Dr Kate Granger in the UK. Our objectives were twofold: first, to measure rates of introduction in an Irish hospital setting by both consultant and non-consultant hospital doctors. Second to establish whether such practices we...

journal_title：Postgraduate medical journal

authors： Gillen P,Sharifuddin SF,O'Sullivan M,Gordon A,Doherty EM

更新日期：2018-04-01 00:00:00

abstract：:The causes of death, as determined by autopsy, in 10 patients dying from the acute effects of phaeochromocytoma were myocardial infarction (five patients), left ventricular failure (two patients), cerebral haemorrhage (two patients) and circulatory collapse with malignant phaeochromocytoma (one patient). Most patients...

journal_title：Postgraduate medical journal

authors： Cohen CD,Dent DM

更新日期：1984-02-01 00:00:00

abstract：PURPOSE OF THE STUDY:Grit is characterised by the ability to persevere during difficulties and maintain a sustained effort over an extended period of time. Throughout their careers, doctors will experience many periods of stress and difficulty. This may result in burnout, defined by the presence of exhaustion and disen...

journal_title：Postgraduate medical journal

authors： Halliday L,Walker A,Vig S,Hines J,Brecknell J

更新日期：2017-07-01 00:00:00

abstract：:The painful pathological condition of the penis, priapism, is usually associated with serious destructive changes which lead to impotence if treatment is with-held or delayed. Conservative therapy is slow, uncertain and usually ineffective. Early surgical decompression of the corpora cavernosa, repeated if necessary, ...

journal_title：Postgraduate medical journal

authors： Ihekwaba FN,Lawani J

更新日期：1981-02-01 00:00:00

abstract：:Spironolactone therapy is a well-known cause of hyperkalaemia, but in susceptible patient, it may also be associated with metabolic acidosis. We report a case of severe renal tubular acidosis (Type IV) with life-threatening hyperkalaemia caused by spironolactone, and discuss the mechanisms by which this may occur. ...

journal_title：Postgraduate medical journal

authors： O'Connell JE,Colledge NR

更新日期：1993-11-01 00:00:00

abstract：:We report a patient who developed persistent nephrogenic diabetes insipidus associated with renal tubular acidosis, renal resistance to parathyroid hormone, aminoaciduria and proximal tubule pattern proteinuria in the presence of a reduced glomerular filtration rate (19-24 ml/min). A review of the previous reports of ...

journal_title：Postgraduate medical journal

authors： Neithercut WD,Spooner RJ,Hendry A,Dagg JH

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a chronic, multisystem disease characterised by non-necrotising granulomatous inflammation of unknown aetiology. Most commonly, the lungs, lymph nodes, skin and eyes are affected in sarcoidosis; however, nervous system involvement occurs in approximately 5%-15% of cases. Any part of the nervou...

journal_title：Postgraduate medical journal

authors： Radwan W,Lucke-Wold B,Robadi IA,Gyure K,Roberts T,Bhatia S

更新日期：2017-07-01 00:00:00

abstract：:We describe two patients with diabetes mellitus and associated neuropathy, who presented with painless foot swelling and no history of trauma. X-Rays revealed recent underlying fractures-in one of a metatarsus, and the other of a proximal phalanx. These were assumed to be 'stress' fractures unassociated with pain beca...

journal_title：Postgraduate medical journal

authors： Gill G,Benbow S,Tesfaye S,Kaczmarczyk E,Kaye L

更新日期：1997-04-01 00:00:00