Abstract:
:Little is known about orthostatic blood pressure regulation in acute stroke. We determined postural haemodynamic responses in 40 patients with acute stroke (mild or moderate severity) and 40 non-stroke control in-patients, at two days ('Day 1') and one week ('Week 1') post-admission. Following a 10-minute supine rest and baseline readings, subjects sat up and blood pressure and heart rate were taken for 5 minutes. The procedure was repeated with subjects moving from supine to the standing posture. Haemodynamic changes from supine data were analysed. On standing up, the control group had a transient significant fall in mean arterial blood pressure on Day 1 but not Week 1. No significant changes were seen on either day when sitting up. In contrast to controls, the stroke group showed increases in mean arterial blood pressure on moving from supine to the sitting and standing positions on both days. Persistent postural hypotension defined as > or = 20 mmHg systolic fall occurred in < 10% of either of the study groups on both days. Sitting and standing heart rates in both groups were significantly faster than supine heart rate on both days. The orthostatic blood pressure elevation is consistent with sympathetic nervous system overactivity which has been reported in acute stroke. Upright positioning as part of early rehabilitation and mobilisation following mild-to-moderate stroke would, therefore, not predispose to detrimental postural reductions in blood pressure.
journal_name
Postgrad Med Jjournal_title
Postgraduate medical journalauthors
Panayiotou B,Reid J,Fotherby M,Crome Pdoi
10.1136/pgmj.75.882.213subject
Has Abstractpub_date
1999-04-01 00:00:00pages
213-8issue
882eissn
0032-5473issn
1469-0756journal_volume
75pub_type
临床试验,杂志文章abstract::Clomipramine may affect reproduction in male rats and dogs, while other psychotropic drugs can affect sperm motility in vitro. This study investigates the motility of hamster sperm and the fertilization of hamster eggs in vitro with epididymal sperm from alpha-chlorohydrin-pretreated males, and after preincubation wit...
journal_title:Postgraduate medical journal
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::New-onset seizures are frequent manifestations of central nervous system disorders in patients infected with human immunodeficiency virus (HIV). Seizures are more common in advanced stages of the disease, although they may occur early in the course of illness. In the majority of patients, seizures are of the generalis...
journal_title:Postgraduate medical journal
pub_type: 杂志文章,评审
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abstract::A patient is described who developed acute peripheral neuropathy of Guillain-Barré type occurring shortly after commencement of captopril for moderately severe hypertension and resolving after discontinuation of the drug. ...
journal_title:Postgraduate medical journal
pub_type: 杂志文章
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journal_title:Postgraduate medical journal
pub_type: 杂志文章,多中心研究
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abstract::A case of acute necrotizing pancreatitis in a 53-year-old man with an ectopic adrenocorticotrophin (ACTH) producing bronchial carcinoma is described. The aetiology of acute pancreatitis in relation to steroid therapy and malignancy is discussed and it is suggested that excess endogenous steroid production may also cau...
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pub_type: 杂志文章
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pub_type: 历史文章,杂志文章
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journal_title:Postgraduate medical journal
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1979-01-01 00:00:00
abstract:PURPOSE OF THE STUDY:Genome-wide association studies have revealed an association of ADAMTS7 polymorphisms with the risk of cardiovascular diseases. Nonetheless, the role of ADAMTS7 polymorphisms on myocardial infarction (MI) risk remains poorly understood. Here, we aim to evaluate the effect of ADAMTS7 tag single nucl...
journal_title:Postgraduate medical journal
pub_type: 杂志文章
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更新日期:2019-09-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章
doi:10.1136/postgradmedj-2015-133722
更新日期:2016-09-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章,评审
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更新日期:2016-05-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章
doi:10.1136/pgmj.67.788.571
更新日期:1991-06-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章
doi:10.1136/postgradmedj-2012-100033rep
更新日期:2012-10-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章
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更新日期:1993-11-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章
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更新日期:1979-09-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 临床试验,杂志文章
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章
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更新日期:1980-04-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
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journal_title:Postgraduate medical journal
pub_type: 杂志文章
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journal_title:Postgraduate medical journal
pub_type: 杂志文章
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journal_title:Postgraduate medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1986-01-01 00:00:00
abstract::Candida albicans peritonitis developed in a 48-year-old man with a perforated gastric ulcer who subsequently was treated with intravenous amphotericin B. The drug penetrated well into the inflamed peritoneal cavity and eradicated the organism from the peritoneal fluid. Nevertheless, at post-mortem, Candida organisms w...
journal_title:Postgraduate medical journal
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:1993-05-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:1985-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:1995-02-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1987-02-01 00:00:00
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journal_title:Postgraduate medical journal
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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