Bone dysplasias and mental functioning.

abstract：:Prostate cancer is receiving ever more publicity with the result that more men are having their prostate specific antigen checked and a greater proportion of men are diagnosed with potentially curable localised disease. Advances in the therapeutic modalities including radical surgery, external beam radiotherapy, and b...

journal_title：Postgraduate medical journal

authors： Bott SR,Birtle AJ,Taylor CJ,Kirby RS

更新日期：2003-10-01 00:00:00

abstract：:Mild and self-limiting fever following bleomycin use is common, and a fatal hyperpyrexial response occurs rarely. In previously reported cases, such hyperpyrexia occurred either after the initial administration of the drug or during subsequent therapy following an initial pyrexial response. We describe a fatal hyperpy...

journal_title：Postgraduate medical journal

authors： Leung WH,Lau JY,Chan TK,Kumana CR

更新日期：1989-06-01 00:00:00

abstract：:This is a case report of a boy who presented with unilateral foot drop approximately 1 year after traumatic injury from skateboarding. Exploratory surgical operation was eventually performed, and histological examination of the surgical specimen revealed leprous peripheral neuropathy of the peroneal nerve. The patient...

journal_title：Postgraduate medical journal

authors： Choe W

更新日期：1994-02-01 00:00:00

abstract：:A patient presented with retroperitoneal fibrosis but without any ureteric obstruction. The diagnosis was made by an abdominal CT scan and also at laparotomy. Post-operatively, she developed hypertensive encephalopathy. An isotope renogram with captopril was abnormal but not diagnostic of renal artery stenosis. The pa...

journal_title：Postgraduate medical journal

authors： Das D,Brigg J,Brown CM

更新日期：1999-12-01 00:00:00

abstract：:A patient is described who developed mild hyponatraemia on two occasions when treated with bendrofluazide alone, but severe hyponatraemia when treated with the combination of enalapril and bendrofluazide. ...

journal_title：Postgraduate medical journal

authors： Collier JG,Webb DJ

更新日期：1987-12-01 00:00:00

abstract：:Programmed cell death (PCD) is an important terminal pathway for cells of multicellular organisms, and is involved in a variety of biological events that include morphogenesis, maintenance of tissue homeostasis, and elimination of harmful cells. Dysfunction of PCD leads to various diseases in humans, especially variou...

journal_title：Postgraduate medical journal

authors： Sun Y,Peng ZL

更新日期：2009-03-01 00:00:00

abstract：:The anaesthetic properties of propofol ('Diprivan') have been described previously. This report summarizes additional studies designed to investigate some aspects of the general pharmacology of propofol. Following recovery from anaesthesia with propofol there was no evidence of any central anticholinergic or anticonvu...

journal_title：Postgraduate medical journal

authors： Glen JB,Hunter SC,Blackburn TP,Wood P

更新日期：1985-01-01 00:00:00

abstract：:Long lists of causes of peripheral neuropathy make peripheral nerve disease a dry and uninspiring subject. A simple scheme based on the answers to just six questions should enable the clinician to recognise characteristic patterns, investigate relevant subgroups appropriately, and identify treatable disorders quickly:...

journal_title：Postgraduate medical journal

authors： Overell JR

更新日期：2012-02-01 00:00:00

abstract：:Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage as defined by the UICC-TNM and American Joint Committee on Cancer classifications. Tumour extent, lymph node status, tumour grade and the assessment of lymphatic and venous invasion are still the most important morphological progn...

journal_title：Postgraduate medical journal

authors： Zlobec I,Lugli A

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The prognostic value of serum uric acid (SUA) for incident acute coronary syndrome (ACS) in hypertensive subjects is uncertain. Therefore, the present study examined the association between SUA and incident ACS in a large cohort of Chinese hypertensive adults. METHODS:This was a retrospective cohort study, ...

journal_title：Postgraduate medical journal

authors： Shen G,Huang JY,Yu YL,Liu L,Chen CL,Zhang B,Huang YQ,Feng YQ

更新日期：2020-02-01 00:00:00

abstract：:A young man developed acute renal failure and hypercalcaemia following severe burns. The hypercalcaemia was initially controlled by haemodialysis, but it persisted after return of renal function. Plasma PTH was inappropriately elevated, but the nephrogenous cyclic adenosine monophosphate level was low; thus the PTH wa...

journal_title：Postgraduate medical journal

authors： Evans RA,Lawrence PJ,Thanakrishnan G,Hills E,Wong SY,Dunstan CR

更新日期：1986-05-01 00:00:00

abstract：:We describe two patients with diabetes mellitus and associated neuropathy, who presented with painless foot swelling and no history of trauma. X-Rays revealed recent underlying fractures-in one of a metatarsus, and the other of a proximal phalanx. These were assumed to be 'stress' fractures unassociated with pain beca...

journal_title：Postgraduate medical journal

authors： Gill G,Benbow S,Tesfaye S,Kaczmarczyk E,Kaye L

更新日期：1997-04-01 00:00:00

abstract：:This review presents our experience in the use of propranolol in the management of cardiac infarction. The drug has now been shown to have a definite place, not only in the prevention of cardiac infarction, but also in the treatment of some of the complications. The drug has also been advocated because it may minimiz...

journal_title：Postgraduate medical journal

authors： Sloman G,Hunt D,Ross D

更新日期：1976-01-01 00:00:00

abstract：:A case of ovarian carcinoma and systemic amyloidosis in a 64 year old woman with nephrotic syndrome is reported. Immunohistochemical study of renal and rectal biopsy specimens revealed the presence of amyloidosis AA antigens, consistent with secondary amyloidosis. The absence of chronic inflammatory or infectious dise...

journal_title：Postgraduate medical journal

authors： Fernandez-Miranda C,Mateo S,Gonzalez-Gomez C,Ballestin C

更新日期：1994-07-01 00:00:00

abstract：:Very few cases of acquired severe copper deficiency have been described. The principal effects are haematological, but the precise abnormalities are uncertain due to the possible association of other deficiencies. A case of isolated severe copper deficiency associated with late onset hypogammaglobulinaemia is reported...

journal_title：Postgraduate medical journal

authors： Oppenheimer SM,Hoffbrand BI,Dormandy TL,Parker N,Wickens DG

更新日期：1987-03-01 00:00:00

abstract：:This study assesses the economic benefits of misoprostol in the prophylaxis of gastric ulcers larger than 0.3 cm in patients with osteoarthritis receiving non-steroidal anti-inflammatory drugs. Independent epidemiological data were obtained for patients in Scotland and the West Midlands. Co-diagnosis of arthritis with...

journal_title：Postgraduate medical journal

authors： Knill-Jones R,Drummond M,Kohli H,Davies L

更新日期：1990-08-01 00:00:00

abstract：:The side effects of conventional non-steroidal anti-inflammatory drugs (NSAIDs) on the stomach is undoubtedly a serious public health problem contributing significantly to the morbidity and mortality of patients receiving these drugs. However, the damage of NSAIDs is not confined to the stomach. Indeed the short term ...

journal_title：Postgraduate medical journal

authors： Adebayo D,Bjarnason I

更新日期：2006-03-01 00:00:00

abstract：:Fifteen patients who had undergone a 14 inches X 4 inches jejuno-ileal bypass operation for obesity, 3 to 4 years earlier, were investigated by iliac bone biopsy, radiology and routine biochemistry, including 25-hydroxy-vitamin D and parathyroid hormone estimations. Two patients had histological osteomalacia which was...

journal_title：Postgraduate medical journal

authors： Gilmore IT,Eastwood JB,Ellis WR,Luck VA,Fenton S,O'Grady AJ,Harris E,Murray-Lyon IM

更新日期：1983-05-01 00:00:00

abstract：:Ultrasound guidance has been reported to facilitate the performance of lumbar punctures (LPs). However, the use of ultrasound guidance has not yet received consistent conclusions. We performed a systematic review and meta-analysis to determine the efficacy of ultrasound-guided LPs. PubMed, Embase and the Cochrane Libr...

journal_title：Postgraduate medical journal

authors： Shu L,Huang J,Liu JC

更新日期：2021-01-01 00:00:00

abstract：:Parasites in the human breast are uncommon but not rare. Cysticercus and filariasis in fine needle breast aspirates have been documented and their cytomorphology is well characterised. However, the host tissue response to these parasites and the factors responsible for their initiation are not clear. Over a 21 year pe...

journal_title：Postgraduate medical journal

authors： Sahai K,Kapila K,Verma K

更新日期：2002-03-01 00:00:00

abstract：:Between 1975 and 1982 in 2 centres in Glasgow, 53 previously untreated patients with aggressive non-Hodgkin's lymphomas received chemotherapy consisting of one of the following regimens-CVP, MOPP, CHOP or BACOP. Twenty nine patients (55%) entered complete remission (CR), 20 (38%) had partial remission (PR) and 4 (7%) ...

journal_title：Postgraduate medical journal

authors： Cunningham D,Hepplestone A,Gilchrist NL,Dagg JH,Evans IL,Soukop M

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To examine the current attitudes towards the prevention of venous thromboembolism among a cohort of surgeons. DESIGN:A postal survey, comprising a questionnaire covering various aspects of venous thromboembolism prophylaxis was sent to all (n=84) consultant general surgeons in Wales. RESULTS:Replies were re...

journal_title：Postgraduate medical journal

authors： Williams EV,Williams RS,Hughes JL,Williams KL,Foster ME,Lewis MH

更新日期：2002-02-01 00:00:00

abstract：:Liver transplantation is a useful treatment for end stage liver disease of all aetiologies but recurrent disease presents an ongoing challenge, particularly for hepatitis C virus (HCV) where recurrence is almost universal. Immunosuppression is needed for all patients after transplantation and should be tailored to the...

journal_title：Postgraduate medical journal

authors： Gee I,Alexander G

更新日期：2005-12-01 00:00:00

abstract：:We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient...

journal_title：Postgraduate medical journal

authors： Baruch Y,Ben-Arie Y,Kerner H,Lorber M,Best LA,Gershoni-Baruch R

更新日期：1991-04-01 00:00:00

abstract：:A case of skin necrosis at the sites of injection of subcutaneous heparin is described. The patient went on to develop heparin-induced thrombocytopenia and pulmonary embolism. Review of the previously described cases of heparin-associated skin necrosis reveals that this sequence of events is not uncommon. ...

journal_title：Postgraduate medical journal

authors： Fowlie J,Stanton PD,Anderson JR

更新日期：1990-07-01 00:00:00

abstract：:Two patients with a rise in cardiac troponin T (cTnT) concentrations during the course of lobar pneumonia, without any evidence of acute coronary syndrome or renal failure, are presented. The increase in cTnT concentration is considered a highly sensitive marker of cardiac injury, although it may also rise in other co...

journal_title：Postgraduate medical journal

authors： Weinberg I,Cukierman T,Chajek-Shaul T

更新日期：2002-04-01 00:00:00

abstract：:In the 1920s Moynihan described acute pancreatitis as "..the most terrible of all intra-abdominal calamities". He established a practice of immediate surgical intervention to remove the toxic products accumulating in the peritoneal cavity, and this treatment was endorsed by most centres, remaining the standard therapy...

journal_title：Postgraduate medical journal

authors： Skaife P,Kingsnorth AN

更新日期：1996-05-01 00:00:00

abstract：:Fasting plasma and urinary calcium and urinary hydroxyproline are known to rise at the menopause, reflecting increased bone resorption. Oestradiol valerate and cyclic oestradiol valerate/DL-norgestrel are shown to reduce this evidence of increased bone loss. It is concluded that these preparations will be effective in...

journal_title：Postgraduate medical journal

authors： Crilly RG,Marshall DH,Nordin BE

更新日期：1978-01-01 00:00:00

abstract：:In severe appendicitis, the effect of a single intravenous dose of metronidazole (500 mg) was compared with cefoxitin (1 g). The antibiotics were given by random allocation once the diagnosis had been established at operation. In the metronidazole group, 5 out of 48 patients developed a wound infection whilst in hospi...

journal_title：Postgraduate medical journal

authors： Corder AP,Bates T,Prior JE,Harrison M,Donaldson PJ

更新日期：1983-11-01 00:00:00

abstract：:The clinical features, treatment and survival of 36 patients with microscopic polyarteritis diagnosed between 1957-1988 have been reviewed. All had a focal segmental necrotizing glomerulonephritis on renal biopsy with evidence of a small vessel vasculitis. Most had a prodromal illness of less than 1 month. Severity of...

journal_title：Postgraduate medical journal

authors： Rodgers H,Guthrie JA,Brownjohn AM,Turney JH

更新日期：1989-08-01 00:00:00