Prostate cancer management: (1) an update on localised disease.

abstract：CONTEXT:In Sweden, patient malpractice claims are handled administratively and compensated if an independent physician review confirms patient injury resulting from medical error. Full access to all malpractice claims and hospital discharge data for the country provided a unique opportunity to assess the validity of pa...

journal_title：Postgraduate medical journal

authors： Pukk-Härenstam K,Ask J,Brommels M,Thor J,Penaloza RV,Gaffney FA

更新日期：2009-02-01 00:00:00

abstract：:Ruptured abdominal aortic aneurysm currently accounts for about 1 in 200 deaths and is a critical surgical emergency with an average hospital mortality of 50%. The combination of acute massive haemorrhage in an elderly patient with pre-existing medical disease is highly lethal and a major challenge for any health care...

journal_title：Postgraduate medical journal

authors： Brimacombe J,Berry A

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To establish a cerebral hypoxia ischaemic model in piglets and to explore the early diffusion weighted imaging (DWI) as well as the expression of heat shock protein 70 (HSP70) with hypoxic ischaemic encephalopathy (HIE). METHODS:Twenty four 3 day old piglets were permanently ligated common carotid arteries b...

journal_title：Postgraduate medical journal

authors： Cheng Y,Liu GR,Guan JT,Guo YL,Li YK,Wu RH

更新日期：2005-09-01 00:00:00

abstract：:Antenatal appendicular perforation leading to localized meconium peritonitis and intestinal obstruction is reported in a premature neonate. The baby was successfully treated by a limited ileocaecal resection. ...

journal_title：Postgraduate medical journal

authors： Narasimharao KL,Mitra SK,Pathak IC

更新日期：1987-11-01 00:00:00

abstract：:The relative prevalence of abnormalities of coronary flow reserve and oesophageal function was ascertained in 32 syndrome X patients with typical angina chest pain, a positive exercise test, and normal coronary arteries. Coronary flow reserve in response to a hyperaemic dose of papaverine was measured using an intraco...

journal_title：Postgraduate medical journal

authors： Chauhan A,Mullins PA,Gill R,Taylor G,Petch MC,Schofield PM

更新日期：1996-02-01 00:00:00

abstract：:Psoriasis (PsO) is a chronic skin disease. This study aims to evaluate clinical and subclinical response to calcipotriol+betamethasone foam, in patients with PsO, comparing, for the first time, data from microvascular ultrasound (MicroV) and shear wave elastography (SWE) with Psoriasis Area and Severity Index (PASI). ...

journal_title：Postgraduate medical journal

authors： Guazzaroni M,Ferrari D,Lamacchia F,Marisi V,Tatulli D,Marsico S,Orlacchio A,Floris R,Bianchi L,Dattola A

更新日期：2021-01-01 00:00:00

abstract：:We describe the case of an acromegalic woman with primary infertility who was treated with clomiphene, and subsequently developed pituitary apoplexy. ...

journal_title：Postgraduate medical journal

authors： Walker AB,Eldridge PR,MacFarlane IA

更新日期：1996-03-01 00:00:00

abstract：PURPOSE OF THE STUDY:Genome-wide association studies have revealed an association of ADAMTS7 polymorphisms with the risk of cardiovascular diseases. Nonetheless, the role of ADAMTS7 polymorphisms on myocardial infarction (MI) risk remains poorly understood. Here, we aim to evaluate the effect of ADAMTS7 tag single nucl...

journal_title：Postgraduate medical journal

authors： Liang LL,Zhou YL,Cheng J,Xiao YT,Tang ZB,Liu SM,Lian JC,Wang XX,Liu X,Xiong XD

更新日期：2019-09-01 00:00:00

abstract：:Reports of malignant melanoma involving the heart usually describe metastatic spread of pigmented (melanotic) forms of this tumour. We describe, and illustrate, a patient presenting with features related to cardiac tamponade and intracardiac obstruction. Transthoracic echocardiography initially showed a large mass wit...

journal_title：Postgraduate medical journal

authors： Dubrey S,Grocott-Mason R,Mittal T,Burke M

更新日期：2008-03-01 00:00:00

abstract：:This study assesses the economic benefits of misoprostol in the prophylaxis of gastric ulcers larger than 0.3 cm in patients with osteoarthritis receiving non-steroidal anti-inflammatory drugs. Independent epidemiological data were obtained for patients in Scotland and the West Midlands. Co-diagnosis of arthritis with...

journal_title：Postgraduate medical journal

authors： Knill-Jones R,Drummond M,Kohli H,Davies L

更新日期：1990-08-01 00:00:00

abstract：:A pre-term infant being ventilated for respiratory distress syndrome developed severe localized pulmonary interstitial emphysema which was successfully treated by selective bronchial intubation. ...

journal_title：Postgraduate medical journal

authors： Oliver JE,Smith IJ

更新日期：1984-01-01 00:00:00

abstract：:Ulcerative colitis is not commonly associated with recognizable pulmonary disease and only four sporadic cases of sarcoidosis in association with ulcerative colitis have been previously reported. However, in a series of 680 patients with ulcerative colitis, pulmonary or extra-pulmonary sarcoidosis has at some stage be...

journal_title：Postgraduate medical journal

authors： Barr GD,Shale DJ,Jewell DP

更新日期：1986-05-01 00:00:00

abstract：:Patients with Cushing's syndrome rarely become pregnant. This is a high risk situation both for the fetus and the mother, if untreated. We report a patient with Cushing's syndrome due to adrenocortical adenoma who became pregnant and was successfully treated with ketoconazole during the last period of pregnancy. ...

journal_title：Postgraduate medical journal

authors： Amado JA,Pesquera C,Gonzalez EM,Otero M,Freijanes J,Alvarez A

更新日期：1990-03-01 00:00:00

abstract：:Retroperitoneal fibrosis, either idiopathic or associated with aortic inflammatory aneurysm, is a chronic fibrotic disease that causes progressive obstruction of ureters and vessels around the lower abdominal aorta. Treatment is often difficult (surgery) or hazardous (steroids). We report a case of a woman with retrop...

journal_title：Postgraduate medical journal

authors： Frankart L,Lorge F,Donckier J

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF STUDY:The aim of the study is to describe the prevalence of illicit drug use in England and Wales using data from the UK Survey of Non-Medical Use of Prescription Drugs (NMURx) programme and to compare against the well-established Crime Survey England and Wales (CSEW). The rationale is that recreational and ...

journal_title：Postgraduate medical journal

authors： Ng FL,Rockhill K,Black J,May KP,Whittington MD,Wood DM,Dargan PI,Green JL

更新日期：2018-11-01 00:00:00

abstract：:Stroke is the third most common cause of death in developed countries. In England and Wales, 1000 people under the age of 30 have a stroke each year. Cocaine is the most commonly used class A drug, and the first report of cocaine-induced stroke was in 1977. Since the development of alkaloidal "crack" cocaine in the 19...

journal_title：Postgraduate medical journal

authors： Treadwell SD,Robinson TG

更新日期：2007-06-01 00:00:00

abstract：:The majority of second-generation calcium antagonists are dihydropyridines, some of which show vascular selectivity. Several new dihydropyridines have been developed with comparable pharmacodynamic properties to existing calcium antagonists in this class and greatly improved kinetic half-lives. Of these agents, amlodi...

journal_title：Postgraduate medical journal

authors： Opie LH

更新日期：1991-01-01 00:00:00

abstract：:It is a paradigm in cancer treatment that early detection and treatment improves survival. However, although screening measures lead to a higher rate of detection, for small bulk localised prostate cancer it remains unclear whether early detection and early treatment will lead to an overall decrease in mortality. The ...

journal_title：Postgraduate medical journal

authors： Mazhar D,Waxman J

更新日期：2002-10-01 00:00:00

abstract：:Prostatic involvement is an unusual complication of Wegener's granulomatosis. We report two cases with this complication and emphasize the importance of recognizing this manifestation in diagnosis and management of the disease condition. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Woolf A,Falzon M

更新日期：1987-01-01 00:00:00

abstract：:Thirty patients who had undergone major abdominal surgery were randomly assigned to a continuous infusion of either 0.45 mg meptazinol/kg/hr or 0.3 mg pethidine/kg/hr. Analgesia was assessed by rating scale, ranging from 0 (no pain) to 10 (unbearable pain), and by questionnaire. Respiration rate was closely monitored ...

journal_title：Postgraduate medical journal

authors： Church JJ

更新日期：1983-01-01 00:00:00

abstract：:" Blo -Bag", a new disposable spacer device, has been tested in conjunction with Duovent metered dose inhaler. Duovent produced a significant bronchodilatation for the duration of the study. When delivered by the " Blo -Bag" it produced a significantly greater increase in peak expiratory flow rate than when delivered ...

journal_title：Postgraduate medical journal

authors： Woodcock A,Humberstone A,Kendall J,Pierce A

更新日期：1984-01-01 00:00:00

abstract：:A case of deliberate overdose of barium sulphide in a psychiatric setting is presented, with resulting flaccid paralysis, malignant arrhythmia, respiratory arrest and severe hypokalaemia, but ultimately with complete recovery. The degree of paralysis appears to be related directly to serum barium levels. The value of ...

journal_title：Postgraduate medical journal

authors： Thomas M,Bowie D,Walker R

更新日期：1998-09-01 00:00:00

abstract：:Although an extensive literature exists on factors controlling sodium excretion in animal experimental models of heart failure, the relevance of these to the human condition remains largely unexplored. Increased renal sympathetic stimulation is considered responsible for heightened urinary sodium retention. Stimulatio...

journal_title：Postgraduate medical journal

authors： Good J,Frost G,Oakley CM,Cleland JG

更新日期：1992-01-01 00:00:00

abstract：:Three patients are described in whom one or more carotid territory transient ischaemic attacks (TIAs) were preceded by sneezing, straining, or bending over. It is argued that the mechanism involved dislodgment of embolic material from the site of carotid atheroma. This mechanism should be considered as an alternative ...

journal_title：Postgraduate medical journal

authors： Harrison MJ

更新日期：1999-03-01 00:00:00

abstract：:Forty patients with seasonal rhinitis and a proven sensitivity to pollens were studied for 2 weeks during the pollen season of 1982. The study was carried out according to a double-blind, double-dummy design. All patients received 100 micrograms beclomethasone dipropionate (BDP) into each nostril twice daily (400 micr...

journal_title：Postgraduate medical journal

authors： Dunn AM,Wilson RS,Baggott PJ

更新日期：1984-06-01 00:00:00

abstract：:Disc herniation at the thoracic the spine level is more common than generally thought. Localisation of pain may be vague and may erroneously point to cardiopulmonary, gastrointestinal, genito-urinary or even psychiatric disease. Magnetic resonance imaging is the investigation of choice, especially if spinal cord compr...

journal_title：Postgraduate medical journal

authors： Pal B,Johnson A

更新日期：1997-07-01 00:00:00

abstract：:Clomipramine may affect reproduction in male rats and dogs, while other psychotropic drugs can affect sperm motility in vitro. This study investigates the motility of hamster sperm and the fertilization of hamster eggs in vitro with epididymal sperm from alpha-chlorohydrin-pretreated males, and after preincubation wit...

journal_title：Postgraduate medical journal

authors： Stein DM,Schnieden H

更新日期：1980-01-01 00:00:00

abstract：:Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia...

journal_title：Postgraduate medical journal

authors： Braun GS,Horster S,Wagner KS,Ihrler S,Schmid H

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Postgraduate medical education bodies and national patient safety institutes recommend that trainees develop patient safety competencies such as those for Morbidity and Mortality (M&M) rounds, yet there exists no model for their educational delivery. OBJECTIVE:We studied the effect of a single educational i...

journal_title：Postgraduate medical journal

authors： Mondoux SE,Frank JR,Kwok ESH,Cwinn AA,Lee AC,Calder LA

更新日期：2016-11-01 00:00:00

abstract：:Healthcare workers have a high risk of occupational exposure, more so in developing countries, with high incidence of blood borne diseases and prevalence of unsafe practices. Among the various blood borne diseases, the most common and important ones are HIV infection, hepatitis B, and hepatitis C. Most of the occupati...

journal_title：Postgraduate medical journal

authors： Varghese GM,Abraham OC,Mathai D

更新日期：2003-06-01 00:00:00