Profiles of calcium antagonists in cardiovascular disease with special reference to second-generation agents and amlodipine.

abstract：:Hospital referral is indicated as an emergency for breast infections not settling with oral antibiotics. Referrals to a breast clinic over a period of 6 months were assessed for prior antibiotic prescription. A total of 1078 patients were seen during this period. 91 (8%) patients had been prescribed antibiotics, 71% o...

journal_title：Postgraduate medical journal

authors： Twine C,Gateley CA

更新日期：2006-11-01 00:00:00

abstract：:Two cases of widespread cutaneous vasculitis are described in association with diltiazem, a recently introduced calcium antagonist. In both cases, spontaneous resolution occurred over several weeks following withdrawal of the drug. ...

journal_title：Postgraduate medical journal

authors： Sheehan-Dare RA,Goodfield MJ

更新日期：1988-06-01 00:00:00

abstract：:Prostatic involvement is an unusual complication of Wegener's granulomatosis. We report two cases with this complication and emphasize the importance of recognizing this manifestation in diagnosis and management of the disease condition. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Woolf A,Falzon M

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:This explorative study was triggered by the '#hellomynameis' campaign initiated by Dr Kate Granger in the UK. Our objectives were twofold: first, to measure rates of introduction in an Irish hospital setting by both consultant and non-consultant hospital doctors. Second to establish whether such practices we...

journal_title：Postgraduate medical journal

authors： Gillen P,Sharifuddin SF,O'Sullivan M,Gordon A,Doherty EM

更新日期：2018-04-01 00:00:00

abstract：:Altogether 42 million people worldwide have been infected with HIV, and 12 million have died over the last 20 years. Effective antiretroviral therapy has lead to sustained HIV viral suppression and immunological recovery in patients who have been infected with the virus. The incidence of AIDS has declined in the Weste...

journal_title：Postgraduate medical journal

authors： Thaker HK,Snow MH

更新日期：2003-01-01 00:00:00

abstract：:Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised as a major public health burden. Large-scale epidemiological studies have demonstrated an independent relationship between OSAS and various cardiovascular disorders. The pathogenesis of cardiovascular complications in OSAS is not ...

journal_title：Postgraduate medical journal

authors： Ryan S,Taylor CT,McNicholas WT

更新日期：2009-12-01 00:00:00

abstract：:A 5 year old female child presented with a psoas haematoma as the first manifestation of haemophilia B. Molecular genetic studies were performed to investigate the inheritance of the disorder and the mechanisms by which females may express the haemophilia B phenotype are discussed. ...

journal_title：Postgraduate medical journal

authors： Palmer S,Standen GR,Yates P,Oakhill A

更新日期：1994-11-01 00:00:00

abstract：:Fasting plasma and urinary calcium and urinary hydroxyproline are known to rise at the menopause, reflecting increased bone resorption. Oestradiol valerate and cyclic oestradiol valerate/DL-norgestrel are shown to reduce this evidence of increased bone loss. It is concluded that these preparations will be effective in...

journal_title：Postgraduate medical journal

authors： Crilly RG,Marshall DH,Nordin BE

更新日期：1978-01-01 00:00:00

abstract：:A 17 year old woman presented with severe anaemia due to menorrhagia. On investigation, she was shown to have abnormalities of her haemostatic mechanism consistent with von Willebrand's disease Type I, although there was no family history of this disorder. In addition, she was shown to have severe primary hypothyroidi...

journal_title：Postgraduate medical journal

authors： Blesing NE,Hambley H,McDonald GA

更新日期：1990-06-01 00:00:00

abstract：:The reported impact of human monoclonal IgM antibody (HA1A) on the mortality rate from Gram-negative bacteraemia aroused considerable interest in its use in Glasgow Royal Infirmary. However, the commercial preparation of HA1A was extremely expensive. With this in mind, the Infirmary's Drugs and Therapeutics Committee ...

journal_title：Postgraduate medical journal

authors： Bell E,McCartney C

更新日期：1995-02-01 00:00:00

abstract：:The clinical features of 62 cases of computerized axial tomography scan-proved cerebral haemorrhage and 81 cases of cerebral infarction in the carotid territory have been compared in a retrospective case note survey. The clinical features which can help in making the distinction between haemorrhage and infarction at t...

journal_title：Postgraduate medical journal

authors： Harrison MJ

更新日期：1980-09-01 00:00:00

abstract：:Clinical, endocrinological and computed tomographic features of three patients with unusual manifestations or complications of craniofacial involvement of fibrous dysplasia are presented. One patient with polyostotic fibrous dysplasia presented in late pregnancy with acute onset of bilateral optic nerve compression an...

journal_title：Postgraduate medical journal

authors： Daly BD,Chow CC,Cockram CS

更新日期：1994-01-01 00:00:00

abstract：PURPOSE OF THE STUDY:The aim of this study was to investigate the association of fluid overload, measured by bioelectrical impedance vector analysis (BIVA) and also by accumulated fluid balance, with 30-day mortality rates in patients admitted to the emergency department (ED). DESIGN:We conducted a prospective observa...

journal_title：Postgraduate medical journal

authors： Kammar-García A,Pérez-Morales Z,Castillo-Martinez L,Villanueva-Juárez JL,Bernal-Ceballos F,Rocha-González HI,Remolina-Schlig M,Hernández-Gilsoul T

更新日期：2018-07-01 00:00:00

abstract：:Two cases of pubic osteomyelitis presenting as a painful hip are reported. In both cases the diagnosis was delayed by the unusual presentation and by the limited radiological investigation. Pubic osteomyelitis is rare in childhood but should be considered in the differential diagnosis of the 'irritable hip'. ...

journal_title：Postgraduate medical journal

authors： Weinberg JR,Berman L,Dootson G,Mitchell R

更新日期：1987-04-01 00:00:00

abstract：:The treatment of renal anaemia by recombinant human erythropoietin (EPO) is now well established. Several studies have examined the pharmacokinetics and efficacy of the drug given intravenously, intraperitoneally and subcutaneously and there is increasing evidence that the subcutaneous route has several advantages inc...

journal_title：Postgraduate medical journal

authors： Macdougall IC,Hutton RD,Coles GA,Williams JD

更新日期：1991-01-01 00:00:00

abstract：:A case of skin necrosis at the sites of injection of subcutaneous heparin is described. The patient went on to develop heparin-induced thrombocytopenia and pulmonary embolism. Review of the previously described cases of heparin-associated skin necrosis reveals that this sequence of events is not uncommon. ...

journal_title：Postgraduate medical journal

authors： Fowlie J,Stanton PD,Anderson JR

更新日期：1990-07-01 00:00:00

abstract：:A case of seminoma of the testis complicated by an extensive granulomatous reaction is reported. This reaction was so florid that a benign condition was initially considered until further material for histology was examined and the correct diagnosis made. ...

journal_title：Postgraduate medical journal

authors： Pickard WR,Clark AH,Abel BJ

更新日期：1983-05-01 00:00:00

abstract：:We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement. Some dangers of this therapy and necessary precautions ...

journal_title：Postgraduate medical journal

authors： Burns A,Brown TM,Semple P

更新日期：1983-08-01 00:00:00

abstract：:A young woman with a previous history of anorexia nervosa presented with severe finger clubbing. Urine samples intermittently contained significant amounts of aspartylglucosamine. Liver biopsy showed abnormal cytoplasmic inclusions in phagocytic cells. The patient was found to be abusing senna laxative. ...

journal_title：Postgraduate medical journal

authors： Malmquist J,Ericsson B,Hultén-Nosslin MB,Jeppsson JO,Ljungberg O

更新日期：1980-12-01 00:00:00

abstract：:The case of a woman with a large benign villous papilloma of the rectum, presenting with sodium and water depletion and later complicated by persistent hypokalaemia, is described. The patient also suffered from primary hypogonadism and diabetes. ...

journal_title：Postgraduate medical journal

authors： Bamford JK,Galbraith HJ,Pender BW

更新日期：1965-04-01 00:00:00

abstract：:Hypothyroidism over a lifetime is rare. Such a case is reported due to post-coupling dyshormonogenesis in a patient who had developed an aortic aneurysm. It is proposed that the aortic aneurysm could have arisen as a direct consequence of the hypothyroidism. Furthermore, Reilly bodies, which are deposits of mucopolysa...

journal_title：Postgraduate medical journal

authors： Savage C,Deanfield JE,Jung RT

更新日期：1982-11-01 00:00:00

abstract：:Hypersensitivity reactions to chemotherapy drugs pose significant difficulties in management, especially when no suitable alternative is available or acceptable and delay in continuation of treatment may be life-threatening. Such reactions may be IgE- or non-IgE-mediated and have varied manifestations. Timely recognit...

journal_title：Postgraduate medical journal

authors： Tham EH,Cheng YK,Tay MH,Alcasabas AP,Shek LP

更新日期：2015-03-01 00:00:00

abstract：:Participant modelling, a behaviourally-orientated treatment technique, is an effect method of treating phobias associated with minor medical procedures or apparatus such as needles or intravenous catheters. The steps in this technique are described and two cases of severe needle phobias successfully treated with parti...

journal_title：Postgraduate medical journal

authors： Taylor CB,Ferguson JM,Wermuth BM

更新日期：1977-01-01 00:00:00

abstract：:Eight patients with endobronchial tuberculosis diagnosed on bronchoscopy were treated with antituberculosis drugs and a course of prednisone. The progress of the endobronchial lesions was assessed on repeated examinations. The course of the disease was variable and the endobronchial narrowing improved in two patients ...

journal_title：Postgraduate medical journal

authors： Chan HS,Sun A,Hoheisel GB

更新日期：1990-10-01 00:00:00

abstract：:A deceased 79 year old man with a permanent cardiac pacemaker was due to be cremated, but the pacemaker generator was not detectable by palpation. A hand held metal detector to locate the device so that it could be extracted before cremation. ...

journal_title：Postgraduate medical journal

authors： Gale CP,Mulley GP

更新日期：2005-03-01 00:00:00

abstract：:A 3-year-old girl is described who became oliguric and hypoglycaemic whilst receiving an excessive dose of sulphadiazine. The mechanism of the hypoglycaemia is discussed. ...

journal_title：Postgraduate medical journal

authors： Craft AW,Brocklebank JT,Jackson RH

更新日期：1977-02-01 00:00:00

abstract：:Infants of HBsAg-positive mothers (Group I) as well as those born to women without HBV markers (Group II) were vaccinated with a 10 micrograms dose of a recombinant DNA hepatitis B vaccine within 24 hours after birth according to a 0, 1, and 2 month schedule, with a booster dose planned 12 months later. Vaccination re...

journal_title：Postgraduate medical journal

authors： Meheus A,Alisjahbana A,Vranckx R,Sukadi A,Usman A,Ngantung W,Sugita E,Safary A,André F,Reniers J

更新日期：1987-01-01 00:00:00

abstract：:Serum concentrations of LH, FSH, testosterone and prolactin were measured in patients with hypertension treated with propranolol (34 cases), methyldopa (13 cases), and methyldopa + propranolol (11 cases). The results were compared with those obtained in 18 controls (hospital out-patients). There were no differences in...

journal_title：Postgraduate medical journal

authors： Taylor RG,Crisp AJ,Hoffbrand BI,Maguire A,Jacobs HS

更新日期：1981-07-01 00:00:00

abstract：:Haemorrhage of small bowel origin may prove to be a clinical and diagnostic challenge, particularly when the bleeding is massive and continuous. Such a case is described where the source of blood loss was a jejunal vascular abnormality. ...

journal_title：Postgraduate medical journal

authors： Saunders MP

更新日期：1991-07-01 00:00:00

abstract：:Thirteen patients with mild primary hyperparathyroidism who were taking thiazide diuretics intermittently for periods of up to 18 months were followed up for a mean of 5.3 years. No significant difference was found in either plasma total calcium corrected for albumin or whole blood ionized calcium in these patients be...

journal_title：Postgraduate medical journal

authors： Farquhar CW,Spathis GS,Barron JL,Levin GE

更新日期：1990-09-01 00:00:00