Massive cardiac invasion by amelanotic melanoma with obstructive clinical features.

abstract：:Aspirin was first synthesised 100 years ago and its preparation and marketing is generally reckoned to have been the foundation of the pharmaceutical industry. For most of the time since then it has been used for the relief of pain and fever. The modern phase of aspirin use commenced with the reporting in 1974 of a ra...

journal_title：Postgraduate medical journal

authors： Elwood PC,Hughes C,O'Brien JR

更新日期：1998-10-01 00:00:00

abstract：:We studied two sisters who developed large non-toxic goitres in adolescence. Deiodinase deficiency was diagnosed by a rapid thyroid uptake of radioactive iodine (RAI) at 2 hours associated with a marked fall in thyroidal 131I by 24 hours. Serial RAI scans in the second patient documented evolution of the iodine-defici...

journal_title：Postgraduate medical journal

authors： Hirsch HJ,Shilo S,Spitz IM

更新日期：1986-06-01 00:00:00

abstract：:The use of an emulsion formulation of 2,6-diisopropylphenol (propofol) for induction and maintenance of anaesthesia was compared with methohexitone in 60 patients undergoing termination of pregnancy. In the dosages chosen the two agents appeared to be equi-potent. Propofol was associated with a statistically significa...

journal_title：Postgraduate medical journal

authors： Cundy JM,Arunasalam K

更新日期：1985-01-01 00:00:00

abstract：:Ketonaemia is well documented as a consequence of prolonged starvation, acute alcoholism, and uncontrolled diabetes mellitus. However, its occurrence in acute pancreatitis has not been described. In this report, three patients who manifested ketoacidosis at the time of presentation of acute pancreatitis are described....

journal_title：Postgraduate medical journal

authors： Kabadi UM

更新日期：1995-01-01 00:00:00

abstract：:The new formulation of propofol appears to be approximately equipotent to the previous formulation when used as an infusion to supplement nitrous oxide anaesthesia in patients premedicated with morphine. Preliminary haemodynamic studies indicate that the emulsion formulation causes more arterial hypotension than the o...

journal_title：Postgraduate medical journal

authors： Coates DP,Prys-Roberts C,Spelina KR,Monk CR,Norley I

更新日期：1985-01-01 00:00:00

abstract：:The clinical features of 62 cases of computerized axial tomography scan-proved cerebral haemorrhage and 81 cases of cerebral infarction in the carotid territory have been compared in a retrospective case note survey. The clinical features which can help in making the distinction between haemorrhage and infarction at t...

journal_title：Postgraduate medical journal

authors： Harrison MJ

更新日期：1980-09-01 00:00:00

abstract：:Tienilic acid is a diuretic-uricosuric compound whose natriuretic site of action is in the cortical diluting segment of the distal nephron. Oral doses of 250 mg given to normal human volunteers provided peak blood levels of 10--11 micrograms/ml at 3--4 hours after administration. Approximately 40% of the dose was reco...

journal_title：Postgraduate medical journal

authors： Dubb JW,Stote RM,Maass AR,Hwang BV,Familiar RG,Alexander F

更新日期：1979-01-01 00:00:00

abstract：:Video evaluation of resuscitation is becoming increasingly integrated into practice in a number of clinical settings. The purpose of this review article is to examine how video may enhance clinical care during resuscitation. As healthcare and available therapeutic interventions evolve, re-evaluation of accepted paradi...

journal_title：Postgraduate medical journal

authors： Lowe DJ,Dewar A,Lloyd A,Edgar S,Clegg GR

更新日期：2017-08-01 00:00:00

abstract：:We report the development of synchronous bilateral carpal tunnel syndrome in a woman with metastatic colorectal cancer, undergoing treatment with recombinant interleukin 2. A carpal tunnel decompression was carried out on the hand which was more severely affected, with a gradual recovery in median nerve function. To t...

journal_title：Postgraduate medical journal

authors： Heys SD,Mills KL,Eremin O

更新日期：1992-07-01 00:00:00

abstract：PURPOSE:How medical students learn and develop the characteristics associated with good teaching in medicine is not well known. Information about this process can improve the academic preparation of medical students for teaching responsibilities. The purpose of this study was to determine how different experiences cont...

journal_title：Postgraduate medical journal

authors： Henry BW,Haworth JG,Hering P

更新日期：2006-09-01 00:00:00

abstract：:Tissue auto-antibodies were investigated in fifty-one patients (twenty-five female, twenty-six male) receiving practolol for ischaemic heart disease or dysrhythmias and compared with those found in 204 patients (fifty-eight female, 146 male) with ischaemic heart disease who did not receive practolol. Antinuclear facto...

journal_title：Postgraduate medical journal

authors： Jachuck SJ,Stephenson J,Bird T,Jackson FS,Clark F

更新日期：1977-02-01 00:00:00

abstract：:It is argued that as the major occupational cancer risks become matters of historical interest, research epidemiologists working in the field should broaden their approaches to encompass life style factors. In the investigation of possible low-cancer risks, it no longer makes any sense to confine their data-collecting...

journal_title：Postgraduate medical journal

authors： Roe FJ

更新日期：1990-05-01 00:00:00

abstract：:A patient is described in whom the presenting feature of hypopituitarism was the development of palmar xanthomata associated with type III hyperlipoproteinaemia. Treatment of her secondary hypothyroidism with thyroxine caused resolution of the xanthomata and hyperlipidaemia, but the underlying compositional abnormalit...

journal_title：Postgraduate medical journal

authors： Carr D,Thornes HM,Rutter AC,Finney RD,Turner PR

更新日期：1987-12-01 00:00:00

abstract：PURPOSE OF THE STUDY:Iron deficiency anaemia (IDA) is associated with increased morbidity and mortality in heart failure patients. The aim of our audit was to evaluate the current practice in diagnosis and assessment of IDA in patients admitted with heart failure. STUDY DESIGN:We conducted a retrospective audit of pat...

journal_title：Postgraduate medical journal

authors： Simon S,Ioannou A,Deoraj S,Metaxa S,Mandal AKJ,Missouris CG

更新日期：2020-04-01 00:00:00

abstract：:Epidemiological, laboratory and experimental studies make it clear that dietary cholesterol (DC) and saturated fat, independently and together, are hypercholesterolaemic and atherogenic. Some work suggests that DC, usually given as egg yolk, is the more important, but often they are consumed together. There is a thres...

journal_title：Postgraduate medical journal

authors： Connor WE

更新日期：1980-08-01 00:00:00

abstract：:The in vitro activity of cefaclor was compared with that of cephalexin and cephradine. This new antibiotic was the most active of the oral agents against Haemophilus influenzae (especially non-beta-lactamase producing strains). It was also significantly more active against N. gonorrhoeae and the Enterobacteriaceae. Th...

journal_title：Postgraduate medical journal

authors： Gillett AP,Andrews JM,Wise R

更新日期：1979-01-01 00:00:00

abstract：:We report the case of a 66 year old woman with clinical manifestations of giant-cell arteritis, positive temporal artery biopsy and excellent response to prednisone, who developed massive cerebral infarcts after 5 days of treatment. Computed tomographic and magnetic resonance imaging scans revealed multiple infarcts i...

journal_title：Postgraduate medical journal

authors： Collazos J,García-Moncó C,Martín A,Rodriguez J,Gómez MA

更新日期：1994-03-01 00:00:00

abstract：:Staging for non-small cell lung cancer (NSCLC) requires accurate assessment of the mediastinal lymph nodes which determines treatment and outcome. As radiological staging is limited by its specificity and sensitivity, it is necessary to sample the mediastinal nodes. Traditionally, mediastinoscopy has been used for eva...

journal_title：Postgraduate medical journal

authors： Medford AR,Bennett JA,Free CM,Agrawal S

更新日期：2010-02-01 00:00:00

abstract：:Paradoxical vocal cord motion disorder (PVCM), also called vocal cord dysfunction, is an important differential diagnosis for asthma. The disorder is often misdiagnosed as asthma leading to unnecessary drug use, very high medical utilisation and occasionally tracheal intubation or tracheostomy. Laryngoscopy is the gol...

journal_title：Postgraduate medical journal

authors： Ibrahim WH,Gheriani HA,Almohamed AA,Raza T

更新日期：2007-03-01 00:00:00

abstract：:Granulomatous disorders comprise a large family sharing the histological denominator of granuloma formation. A granuloma is a focal compact collection of inflammatory cells, mononuclear cells predominating, usually as a result of the persistence of a non-degradable product and of active cell mediated hypersensitivity....

journal_title：Postgraduate medical journal

authors： James DG

更新日期：2000-08-01 00:00:00

abstract：:Defence against the reactive oxidants produced during aerobic metabolism is a complex process and is provided by a system of enzymes and antioxidant compounds capable of preventing excess radical production, neutralising free radicals and repairing the damage caused by them. Regulation of the antioxidant system must p...

journal_title：Postgraduate medical journal

authors： Szaleczky E,Prechl J,Fehér J,Somogyi A

更新日期：1999-01-01 00:00:00

abstract：:In 40 hypertensive patients continuous ECG recording was done before and after 30 days treatment with indapamide 2.5 mg. There was no change in heart rate. In addition, the incidence of extrasystoles was not changed in patients in whom the ECG was normal before treatment (30 cases) or in 8 of the 10 patients who had a...

journal_title：Postgraduate medical journal

authors： Haiat R,Lellouch A,Lanfranchi J,Witchitz S

更新日期：1981-01-01 00:00:00

abstract：INTRODUCTION:Doctors in all specialties are involved in making "do not attempt resuscitation" (DNAR) decisions; this can be a difficult and challenging process. Guidelines exist to provide an ethical and legal framework for the process and documentation of these decisions. OBJECTIVE:To audit the documentation of resus...

journal_title：Postgraduate medical journal

authors： Harris D,Davies R

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Asthma, a common childhood condition, often presents with chronic cough. While evaluating for chronic cough, many specialists obtain a baseline chest radiograph (CR) to assess for other causes. Usually read as 'normal', sometimes CRs will reveal evidence of airway inflammation in the form of subtle findings,...

journal_title：Postgraduate medical journal

authors： Abeles M,Akerman M,Halaby C,Pirzada M

更新日期：2020-12-03 00:00:00

abstract：:We describe a patient with primary amyloidosis in whom multiple osteolytic lesions caused by amyloid bone tumours developed, and review the clinical features of the 18 cases with primary amyloidosis in whom destructive bone lesions have been reported. In contrast to amyloidosis associated with multiple myeloma, destru...

journal_title：Postgraduate medical journal

authors： Kramer MR,van Dijk JM,Hadas I,Hershko C

更新日期：1986-11-01 00:00:00

abstract：:The relative prevalence of abnormalities of coronary flow reserve and oesophageal function was ascertained in 32 syndrome X patients with typical angina chest pain, a positive exercise test, and normal coronary arteries. Coronary flow reserve in response to a hyperaemic dose of papaverine was measured using an intraco...

journal_title：Postgraduate medical journal

authors： Chauhan A,Mullins PA,Gill R,Taylor G,Petch MC,Schofield PM

更新日期：1996-02-01 00:00:00

abstract：PURPOSE:Two questions were addressed: (1) How much physical activity do patients with diabetes perform? (2) What are the perceived factors that prevent patients from doing more physical activity? RESEARCH DESIGN AND METHODS:Interview based questionnaires were distributed to consecutive patients attending the Diabetes ...

journal_title：Postgraduate medical journal

authors： Thomas N,Alder E,Leese GP

更新日期：2004-05-01 00:00:00

abstract：:Despite a dramatic decline in mortality over the past years, coronary heart disease is the leading cause of death and disability in the world. At the same time, with the great improvement of medical science, there is a growing population of postmyocardial infarction, postrevascularisation and heart failure survivors. ...

journal_title：Postgraduate medical journal

authors： Shu W,Lei W,Peng S

更新日期：2007-04-01 00:00:00

abstract：:Abnormalities in the serum concentrations of calcium, phosphate, parathyroid hormone and vitamin D develop with declining renal function, leading in turn to renal osteodystrophy. Observational data now suggest that these disturbances in bone and mineral metabolism play an important role in the development of vascular ...

journal_title：Postgraduate medical journal

authors： Connor A

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Despite obesity being a major risk factor for ischaemic stroke (IS), the association between body mass index (BMI) and IS in patients with hypertension remains uncertain. OBJECTIVE:To assess the association between BMI and IS among elderly hypertensive patients in China. METHODS AND RESULTS:We recruited 35...

journal_title：Postgraduate medical journal

authors： Huang J,Liu L,Yu YL,Chen CL,Lo K,Huang YQ,Tang ST,Feng YQ

更新日期：2020-03-27 00:00:00