Ulcerative colitis and sarcoidosis.

Abstract:

:Ulcerative colitis is not commonly associated with recognizable pulmonary disease and only four sporadic cases of sarcoidosis in association with ulcerative colitis have been previously reported. However, in a series of 680 patients with ulcerative colitis, pulmonary or extra-pulmonary sarcoidosis has at some stage been present in eight. These cases are reported in detail. The onset of either condition bore no relationship to the activity or the presence of recognized peripheral manifestations of the other, suggesting that the two diseases were independent. However, three of the patients had the HLA B8 DR3 phenotype which is a higher prevalence than seen in previous studies of either disease alone. Patients with ulcerative colitis who possess this HLA phenotype may possibly be more susceptible to developing sarcoidosis.

journal_name

Postgrad Med J

authors

Barr GD,Shale DJ,Jewell DP

doi

10.1136/pgmj.62.727.341

subject

Has Abstract

pub_date

1986-05-01 00:00:00

pages

341-5

issue

727

eissn

0032-5473

issn

1469-0756

journal_volume

62

pub_type

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