A lesson in the management of testicular cancer in a patient with a solitary testis.

abstract：:Mild and self-limiting fever following bleomycin use is common, and a fatal hyperpyrexial response occurs rarely. In previously reported cases, such hyperpyrexia occurred either after the initial administration of the drug or during subsequent therapy following an initial pyrexial response. We describe a fatal hyperpy...

journal_title：Postgraduate medical journal

authors： Leung WH,Lau JY,Chan TK,Kumana CR

更新日期：1989-06-01 00:00:00

abstract：:A severe case of the cast syndrome is described following Harrington rod distraction and application of a body cast. The case was unusual as it presented late with no warning symptoms and progressed rapidly to death. ...

journal_title：Postgraduate medical journal

authors： Kennedy RH,Cooper MJ

更新日期：1983-08-01 00:00:00

abstract：:We describe the occurrence of primary hyperaldosteronism in two sisters. Although this is only the second published report of familial Conn's syndrome, it does have implications for the relatives of patients with Conn's syndrome and these are discussed. ...

journal_title：Postgraduate medical journal

authors： London N,Swales J,Hollinrake K,Bell P,Heagerty A

更新日期：1992-12-01 00:00:00

abstract：:The case is reported of a patient presenting with recurrent acute myocardial infarction due to stent thrombosis resulting from possible clopidogrel resistance caused by interaction between clopidogrel and anti-tuberculosis drugs. A brief overview of drug interaction as a risk factor for clopidogrel resistance is given...

journal_title：Postgraduate medical journal

authors： Srinivasan M,Smith D

更新日期：2008-04-01 00:00:00

abstract：:Twenty-four hour intragastric acidity was measured in nine volunteer subjects in a single-blind placebo-controlled cross-over study comparing the effects of famotidine with ranitidine. The volunteer subjects received famotidine (40 mg at night), famotidine (20 mg at night), ranitidine (300 mg at night) or placebo in a...

journal_title：Postgraduate medical journal

authors： Santana IA,Lanzon-Miller S,Pounder RE

更新日期：1986-01-01 00:00:00

abstract：:We describe a patient with primary amyloidosis in whom multiple osteolytic lesions caused by amyloid bone tumours developed, and review the clinical features of the 18 cases with primary amyloidosis in whom destructive bone lesions have been reported. In contrast to amyloidosis associated with multiple myeloma, destru...

journal_title：Postgraduate medical journal

authors： Kramer MR,van Dijk JM,Hadas I,Hershko C

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:To determine the utility of a novel Paediatric Consultation Assessment Tool (PCAT). DESIGN:Developed to measure clinicians' communication behaviour with children and their parents/guardian, PCAT was designed according to consensus guidelines and refined at a number of stages. Volunteer clinicians provided vi...

journal_title：Postgraduate medical journal

authors： Howells RJ,Davies HA,Silverman JD,Archer JC,Mellon AF

更新日期：2010-10-01 00:00:00

abstract：:Although an extensive literature exists on factors controlling sodium excretion in animal experimental models of heart failure, the relevance of these to the human condition remains largely unexplored. Increased renal sympathetic stimulation is considered responsible for heightened urinary sodium retention. Stimulatio...

journal_title：Postgraduate medical journal

authors： Good J,Frost G,Oakley CM,Cleland JG

更新日期：1992-01-01 00:00:00

abstract：:Liver transplantation is a useful treatment for end stage liver disease of all aetiologies but recurrent disease presents an ongoing challenge, particularly for hepatitis C virus (HCV) where recurrence is almost universal. Immunosuppression is needed for all patients after transplantation and should be tailored to the...

journal_title：Postgraduate medical journal

authors： Gee I,Alexander G

更新日期：2005-12-01 00:00:00

abstract：:Using the WHO/ISFC definition and recommendations of nomenclature for cardiomyopathies, the aetiology is unknown. Over many years research has concentrated on defining pathogenetic mechanisms and owing to the widespread use of the bioptome-permitting recovery of fresh endomyocardial tissue-myocarditis has emerged as b...

journal_title：Postgraduate medical journal

authors： Olsen EG

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To assess the general use of all non-steroidal anti-inflammatory drugs (NSAID) and their relation to upper gastrointestinal bleeding in view of National Institute for Clinical Excellence guidelines published in July 2001 in the UK. METHODS:Cross sectional study on all patients who were referred for endoscopy...

journal_title：Postgraduate medical journal

authors： Lim CH,Heatley RV

更新日期：2005-04-01 00:00:00

abstract：:This report describes the case history of a middle-aged lady who presented with symptoms and signs over one year leading to a diagnosis of multiple sclerosis. During one of her relapses, she developed trismus--an association that has not been described before in multiple sclerosis. ...

journal_title：Postgraduate medical journal

authors： D'Costa DF,Vania AK,Millac PA

更新日期：1990-10-01 00:00:00

abstract：:Hypertension is the most common chronic disease in the West Indies, and is a major health problem today being among the 10 most common causes of death in the English-speaking territories of the region. Most patients have essential hypertension. Renal failure, stroke, and cardiac failure are the most common complicatio...

journal_title：Postgraduate medical journal

authors： Grell GA

更新日期：1983-10-01 00:00:00

abstract：:The anticoagulant agents heparin and warfarin were introduced before the era of randomised clinical trials. As a result, the indications, dosages and monitoring techniques of these drugs have undergone re-evaluation in multiple clinical trials in the past years. Low molecular weight heparin has been developed, which h...

journal_title：Postgraduate medical journal

authors： Toh CH

更新日期：1997-05-01 00:00:00

abstract：:The painful pathological condition of the penis, priapism, is usually associated with serious destructive changes which lead to impotence if treatment is with-held or delayed. Conservative therapy is slow, uncertain and usually ineffective. Early surgical decompression of the corpora cavernosa, repeated if necessary, ...

journal_title：Postgraduate medical journal

authors： Ihekwaba FN,Lawani J

更新日期：1981-02-01 00:00:00

abstract：:Defence against the reactive oxidants produced during aerobic metabolism is a complex process and is provided by a system of enzymes and antioxidant compounds capable of preventing excess radical production, neutralising free radicals and repairing the damage caused by them. Regulation of the antioxidant system must p...

journal_title：Postgraduate medical journal

authors： Szaleczky E,Prechl J,Fehér J,Somogyi A

更新日期：1999-01-01 00:00:00

abstract：:Left ventricular function was evaluated non-invasively in hypertensive patients treated with indapamide by means of echographically determined velocity of circumferential fibre shortening (VCF). A statistically significant reduction in mean systolic and diastolic blood pressure in both the standing and supine position...

journal_title：Postgraduate medical journal

authors： Horgan JH,O'Donovan A,Teo KK

更新日期：1981-01-01 00:00:00

abstract：:This review presents our experience in the use of propranolol in the management of cardiac infarction. The drug has now been shown to have a definite place, not only in the prevention of cardiac infarction, but also in the treatment of some of the complications. The drug has also been advocated because it may minimiz...

journal_title：Postgraduate medical journal

authors： Sloman G,Hunt D,Ross D

更新日期：1976-01-01 00:00:00

abstract：:Epilepsy is common and serious (prevalence 750 per 100 000) and has an impact upon employment, education, and driving. The diagnosis requires a detailed history including witness account. Clinicians must distinguish seizures particularly from syncope and psychogenic attacks. Electroencephalography and magnetic resonan...

journal_title：Postgraduate medical journal

authors： Hadjikoutis S,Smith PE

更新日期：2005-07-01 00:00:00

abstract：:A study was undertaken to determine the effects of long-term insulin therapy on the development and regression of lipid perturbations and experimental cholesterol atherosclerosis in rabbits: (1) Insulin administration for 15 days significantly reduced plasma lipid levels and free fatty acids in rabbits fed a high-chol...

journal_title：Postgraduate medical journal

authors： Marquié G

更新日期：1978-02-01 00:00:00

abstract：:In recent years, the short Synacthen test (SS) has become the most widely used test to assess adrenal reserve. Despite its frequent use, there are still several areas related to the short Synacthen test (SST), which have no consensus including the optimum sampling times, that is, whether a 60 min post-Synacthen admini...

journal_title：Postgraduate medical journal

authors： Dineen R,Mohamed A,Gunness A,Rakovac A,Cullen E,Barnwell N,Neary C,Behan LA,Boran G,Gibney J,Sherlock M

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Right ventricular (RV) fractional area change and tricuspid annular plane systolic excursion (TAPSE) are recognised methods for assessing RV function. However, the way in which these variables are affected by varying degrees of pulmonary hypertension (PH) has not been well characterised. METHODS:RV end-syst...

journal_title：Postgraduate medical journal

authors： López-Candales A,Dohi K,Rajagopalan N,Edelman K,Gulyasy B,Bazaz R

更新日期：2008-01-01 00:00:00

abstract：:Elective root replacement in Marfan syndrome has improved life expectancy in affected patients. Three forms of surgery are now available: total root replacement (TRR) with a valved conduit, valve sparing root replacement (VSRR) and personalised external aortic root support (PEARS) with a macroporous mesh sleeve. TRR c...

journal_title：Postgraduate medical journal

authors： Treasure T,Takkenberg JJ,Pepper J

更新日期：2016-02-01 00:00:00

abstract：:A total of 187 heart failure patients aged 65-92 years, with pretreatment serum creatinine levels below 200 mumol/l, were monitored for more than 12 months on angiotensin-converting enzyme (ACE) inhibitor therapy. Optimal ACE inhibitor dosage was found in 27% of patients, while a significant deterioration in renal fun...

journal_title：Postgraduate medical journal

authors： Jolobe OM

更新日期：1999-05-01 00:00:00

abstract：:Conventional diagnostic tests for tuberculosis have several limitations and are often unhelpful in establishing the diagnosis of extrapulmonary tuberculosis. Although commercial serological antibody based tests are available, their usefulness in the diagnosis of extrapulmonary tuberculosis is unknown. A systematic rev...

journal_title：Postgraduate medical journal

authors： Steingart KR,Henry M,Laal S,Hopewell PC,Ramsay A,Menzies D,Cunningham J,Weldingh K,Pai M

更新日期：2007-11-01 00:00:00

abstract：:A patient is described who presented with the classical symptomatology and profound electrolyte disturbance of the Verner-Morrison syndrome due to a pancreatic apudoma secreting vasoactive intestinal polypeptide (VIP). Diagnosis was confirmed by plasma VIP as measured by a radio-immunoassay technique now available. It...

journal_title：Postgraduate medical journal

authors： Devine BL,Carmichael HA,Russell RI,Joffe SN

更新日期：1978-08-01 00:00:00

abstract：:Ischaemic heart disease (IHD) related mortality has been on the decline, although its prevalence has been on the rise since the late 1970s. One of the contributing factors to this decline has been improved diagnosis and therapeutic management. Every clinician seeks to answer four key questions while evaluating patient...

journal_title：Postgraduate medical journal

authors： Raj V,Agrawal SK

更新日期：2010-09-01 00:00:00

abstract：:Two patients with lymphoedema of the legs developed recurrent respiratory infections and were found to have panhypogammaglobulinaemia. The early recognition and treatment of this form of immunity deficiency in patients with lymphoedema is important in order to prevent recurrent infections which could cause pulmonary d...

journal_title：Postgraduate medical journal

authors： Lozewicz S,Morris G,Garbett N,Browse N,Slavin B,Cole P

更新日期：1988-01-01 00:00:00

abstract：:This review examines the appropriate timing of intervention in acute pancreatitis. In gallstone pancreatitis, it is now clear that cholecystectomy during the primary admission carries no greater risk of complications than delayed cholecystectomy and enables earlier recovery to normal activity. This course of action pr...

journal_title：Postgraduate medical journal

authors： Johnson CD

更新日期：1993-07-01 00:00:00

abstract：:Renal disease in Churg-Strauss syndrome is generally thought to be benign in nature, thereby distinguishing this rare condition from other necrotizing vasculitides. We report a case in which acute renal failure developed during the aggressive vasculitic phase of the illness requiring dialysis therapy. After one week o...

journal_title：Postgraduate medical journal

authors： Davenport A,McDicken I,Goldsmith HJ

更新日期：1988-09-01 00:00:00