The pathogenesis of dilated cardiomyopathy.

abstract：:Exacerbations of chronic obstructive pulmonary disease impose a considerable burden of morbidity, mortality, and health care cost. Management guidelines outlining best practice, based largely on consensus expert opinion, were produced by a number of organisations during the last decade. Current interest in the field i...

journal_title：Postgraduate medical journal

authors： Hurst JR,Wedzicha JA

更新日期：2004-09-01 00:00:00

abstract：:During one year, out of 1829 faecal specimens examined at the Chelmsford Public Health Laboratory, campylobacters were isolated from 109 (6%), 21 of the positive cultures were from hospital in-patients and 3 were from hospital staff. The remaining 85 isolates were from specimens sent in by general practitioners. The a...

journal_title：Postgraduate medical journal

authors： Bradshaw MJ,Brown R,Swallow JH,Rycroft JA

更新日期：1980-02-01 00:00:00

abstract：:Abnormalities in the serum concentrations of calcium, phosphate, parathyroid hormone and vitamin D develop with declining renal function, leading in turn to renal osteodystrophy. Observational data now suggest that these disturbances in bone and mineral metabolism play an important role in the development of vascular ...

journal_title：Postgraduate medical journal

authors： Connor A

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To assess the evidence for a reduced risk of acute coronary events following comprehensive smoke-free legislation. METHODS:Two independent systematic reviews were undertaken using PubMed, Embase and Science Direct with no date restrictions imposed. Meta-analysis was undertaken using a random effects model to...

journal_title：Postgraduate medical journal

authors： Mackay DF,Irfan MO,Haw S,Pell JP

更新日期：2011-04-01 00:00:00

abstract：:A case of ovarian carcinoma and systemic amyloidosis in a 64 year old woman with nephrotic syndrome is reported. Immunohistochemical study of renal and rectal biopsy specimens revealed the presence of amyloidosis AA antigens, consistent with secondary amyloidosis. The absence of chronic inflammatory or infectious dise...

journal_title：Postgraduate medical journal

authors： Fernandez-Miranda C,Mateo S,Gonzalez-Gomez C,Ballestin C

更新日期：1994-07-01 00:00:00

abstract：:Two coronary prognostic indices for patients treated in a coronary care unit, namely the Norris Index and the Chapman-Gray Index were compared. Both were found to be reliable but the Chapman-Gray Index with its ready reckoner was more convenient and was subject to fewer subjective data. ...

journal_title：Postgraduate medical journal

authors： Habib T,Taylor DJ,Dalton R

更新日期：1979-01-01 00:00:00

abstract：:The addition of amino acid supplements to peritoneal dialysis fluid has been studied in 8 patients with compromised renal function requiring peritoneal dialysis. By the addition of 10 ml of Vamin-glucose solution to each one litre of peritoneal dialysate, amino acid losses were curtailed, no significant alterations oc...

journal_title：Postgraduate medical journal

authors： Jackson MA,Talbot S,Thomas DW,Lee HA

更新日期：1979-09-01 00:00:00

abstract：:Hospital referral is indicated as an emergency for breast infections not settling with oral antibiotics. Referrals to a breast clinic over a period of 6 months were assessed for prior antibiotic prescription. A total of 1078 patients were seen during this period. 91 (8%) patients had been prescribed antibiotics, 71% o...

journal_title：Postgraduate medical journal

authors： Twine C,Gateley CA

更新日期：2006-11-01 00:00:00

abstract：:Acute loss of vision and alcoholic intoxication suggests the possibility of methanol poisoning. In this report we describe an alcoholic patient who complained of blindness after recovering from alcoholic pancreatitis and delirium tremens. Visual acuity was severely impaired and fundoscopy revealed florid bilateral cot...

journal_title：Postgraduate medical journal

authors： Steel JR,Cockcroft JR,Ritter JM

更新日期：1993-02-01 00:00:00

abstract：:Overdosage with cardiac glycosides is well documented, but not usually fatal. A case is described in which cardiac arrest in asystole was associated with a serum digoxin level of 50-4 microgram/1, the highest concentration yet reported after oral administration. ...

journal_title：Postgraduate medical journal

authors： Nicholls DP

更新日期：1977-05-01 00:00:00

abstract：:Gastric cancer is a cause of significant morbidity and mortality. There are several risk factors, with occupation emerging as one of these. There is considerable evidence that occupations in coal and tin mining, metal processing, particularly steel and iron, and rubber manufacturing industries lead to an increased ris...

journal_title：Postgraduate medical journal

authors： Raj A,Mayberry JF,Podas T

更新日期：2003-05-01 00:00:00

abstract：:A host/vector system suitable for large-scale production of HBsAg has been constructed and optimized in terms of the expression plasmid and yeast host strain in order to permit fermentation to very high cell densities. The final expression plasmid contains the coding sequence of the major HBsAg protein (P24) flanked b...

journal_title：Postgraduate medical journal

authors： Harford N,Cabezon T,Colau B,Delisse AM,Rutgers T,De Wilde M

更新日期：1987-01-01 00:00:00

abstract：:In 93 patients with hypertension uncontrolled by bendrofluazide 5 mg plus atenolol 100 mg daily, the effects of adding nifedipine (up to 60 mg/day, n = 31), prazosin (up to 20 mg/day, n = 31), or hydralazine (up to 200 mg/day, n = 31) were compared in a 6 month open random parallel group study. The three drugs did not...

journal_title：Postgraduate medical journal

authors： Ramsay LE,Parnell L,Waller PC

更新日期：1987-02-01 00:00:00

abstract：PURPOSE:Large population studies now demonstrate that frailty is prevalent in all adult age groups. Limited data exist on the association between frailty and surgical outcome in younger patients. The aim of the study was to explore the agreement between frailty identification tools and collect pilot data on their predi...

journal_title：Postgraduate medical journal

authors： Dale MacLaine T,Baker O,Burke D,Howell SJ

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Workforce studies show a declining proportion of UK junior doctors proceeding directly to specialist training, with many taking career breaks. Doctors may be choosing to delay this important career decision. AIM:To assess doctors' views on the timing of choosing a clinical specialty. METHODS:Surveys of two...

journal_title：Postgraduate medical journal

authors： Lachish S,Goldacre MJ,Lambert TW

更新日期：2018-11-01 00:00:00

abstract：:A study was undertaken to determine the effects of long-term insulin therapy on the development and regression of lipid perturbations and experimental cholesterol atherosclerosis in rabbits: (1) Insulin administration for 15 days significantly reduced plasma lipid levels and free fatty acids in rabbits fed a high-chol...

journal_title：Postgraduate medical journal

authors： Marquié G

更新日期：1978-02-01 00:00:00

abstract：:Synovial plicae are normal anatomical structures of the knee that may become symptomatic. MRI is an established technique for evaluating the anatomy of the knee, and it is a valuable tool for detecting plicae because of its high resolution resulting in increased tissue characterisation. At MRI, knee plicae appear as l...

journal_title：Postgraduate medical journal

authors： Vassiou K,Vlychou M,Zibis A,Nikolopoulou A,Fezoulidis I,Arvanitis D

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:To explore the relationship between cognitive impairment and conventional measures of disability in multiple sclerosis (MS), quality of life (QOL) and employment status using the brief international cognitive assessment for multiple sclerosis (BICAMS) in the routine outpatient clinic. METHODS:62 patients wi...

journal_title：Postgraduate medical journal

authors： Campbell J,Rashid W,Cercignani M,Langdon D

更新日期：2017-03-01 00:00:00

abstract：:Parasites in the human breast are uncommon but not rare. Cysticercus and filariasis in fine needle breast aspirates have been documented and their cytomorphology is well characterised. However, the host tissue response to these parasites and the factors responsible for their initiation are not clear. Over a 21 year pe...

journal_title：Postgraduate medical journal

authors： Sahai K,Kapila K,Verma K

更新日期：2002-03-01 00:00:00

abstract：:A case of hyperemesis gravidarum at 9 weeks' gestation is described for which no cause could initially be found. Intravenous feeding was needed as a life preserving measure and following improvement on this regime the patient went into a thyrotoxic crisis which was successfully diagnosed and treated. The continuing pr...

journal_title：Postgraduate medical journal

authors： Valentine BH,Jones C,Tyack AJ

更新日期：1980-10-01 00:00:00

abstract：:Since January 1974, alternate cadaveric renal transplants were treated with antilymphocyte globulin (Behringwerke) om addotopm to prednisone and azathioprine. Thirty patients were treated in this way. 53% of patients receiving ALG had a functioning graft at six months as opposed to 40% in the control group. This diffe...

journal_title：Postgraduate medical journal

authors： Jakobsen J,Flatmark A,Sodal G,Thorsby E

更新日期：1976-01-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is common and may progress to cirrhosis and its complications. The pathogenesis of steatosis and cellular injury is thought to be related mostly to insulin resistance and oxidative stress. Therefore, management entails identification and treatment of metabolic risk factors, im...

journal_title：Postgraduate medical journal

authors： Adams LA,Angulo P

更新日期：2006-05-01 00:00:00

abstract：:Two patients with a rise in cardiac troponin T (cTnT) concentrations during the course of lobar pneumonia, without any evidence of acute coronary syndrome or renal failure, are presented. The increase in cTnT concentration is considered a highly sensitive marker of cardiac injury, although it may also rise in other co...

journal_title：Postgraduate medical journal

authors： Weinberg I,Cukierman T,Chajek-Shaul T

更新日期：2002-04-01 00:00:00

abstract：:About 0.5% of infants are infected in utero with cytomegalovirus (CMV). As many as 20% become mentally retarded and a further substantial proportion suffer lesser degrees of brain damage. The need for a vaccine is greater than in the case of rubella. A live, tissue culture-adapted strain of CMV has been shown to produ...

journal_title：Postgraduate medical journal

authors： Stern H

更新日期：1977-10-01 00:00:00

abstract：:This report deals with a patient with long standing myasthenia gravis treated with a small dose of corticosteroids. The response to treatment was prompt and the post-therapeutic deterioration in function was minimal and cholinergic in nature. It is suggested that the dose of anticholinesterases be reduced concomitantl...

journal_title：Postgraduate medical journal

authors： Dandona P,Corkan EJ,Sladen GE

更新日期：1977-06-01 00:00:00

abstract：PURPOSE OF THE STUDY:Grit is characterised by the ability to persevere during difficulties and maintain a sustained effort over an extended period of time. Throughout their careers, doctors will experience many periods of stress and difficulty. This may result in burnout, defined by the presence of exhaustion and disen...

journal_title：Postgraduate medical journal

authors： Halliday L,Walker A,Vig S,Hines J,Brecknell J

更新日期：2017-07-01 00:00:00

abstract：:For millennia, the smile has been recognised as a powerful communication device, offering benefits to both giver and receiver with few drawbacks. A sign of compassion, empathy and friendliness, smiling can benefit healthcare professionals and their patients, helping to build a relationship of trust. But beware the fal...

journal_title：Postgraduate medical journal

authors： Beamish AJ,Foster JJ,Edwards H,Olbers T

更新日期：2019-02-01 00:00:00

abstract：:Ulcerative colitis is not commonly associated with recognizable pulmonary disease and only four sporadic cases of sarcoidosis in association with ulcerative colitis have been previously reported. However, in a series of 680 patients with ulcerative colitis, pulmonary or extra-pulmonary sarcoidosis has at some stage be...

journal_title：Postgraduate medical journal

authors： Barr GD,Shale DJ,Jewell DP

更新日期：1986-05-01 00:00:00

abstract：:A fatal case of occult foramen magnum meningioma is described which presented with features of cervical myelopathy confirmed by cervical myelogram. Surgical decompression led to initial improvement followed by progressive deterioration and death. Postmortem examination revealed a 4 cm diameter foramen magnum meningiom...

journal_title：Postgraduate medical journal

authors： Chakravarty K,Scott DG,Dick D,Visick J

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Cincinnati Children's Hospital Medical Center created the Intermediate Improvement Science Series (I(2)S(2)) training course to develop organisational leaders to do improvement, lead improvement and get results on specific projects. DESIGN METHODS:Each multidisciplinary class consists of 25-30 par...

journal_title：Postgraduate medical journal

authors： Kaminski GM,Britto MT,Schoettker PJ,Farber SL,Muething S,Kotagal UR

更新日期：2013-02-01 00:00:00