Occupation and gastric cancer.

Abstract:

:Gastric cancer is a cause of significant morbidity and mortality. There are several risk factors, with occupation emerging as one of these. There is considerable evidence that occupations in coal and tin mining, metal processing, particularly steel and iron, and rubber manufacturing industries lead to an increased risk of gastric cancer. Other "dusty" occupations-for example, wood processing, or work in high temperature environments have also been implicated but the evidence is not strong. The mechanism of pathogenesis of gastric cancer is unclear and the identification of causative agents can be difficult. Dust is thought to be a contributor to the pathological process, but well known carcinogens such as N-nitroso compounds have been detected in some environments. Further research on responsible agents is necessary and screening for detection of precursor gastric cancer lesions at the workplace merits consideration.

journal_name

Postgrad Med J

authors

Raj A,Mayberry JF,Podas T

doi

10.1136/pmj.79.931.252

subject

Has Abstract

pub_date

2003-05-01 00:00:00

pages

252-8

issue

931

eissn

0032-5473

issn

1469-0756

journal_volume

79

pub_type

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