Role of angiotensin-converting enzyme inhibitors in early antihypertensive treatment in non-insulin dependent diabetes mellitus.

abstract：:The pharmacokinetics of a single oral dose of clomipramine were examined in a group of depressed patients, 8 female and 2 male with a mean age of 51 years (range 21-78). Their mean clomipramine half-life was 36 hours and mean plasma clomipramine clearance 73 litres per hour, with a wide range in each case. These resul...

journal_title：Postgraduate medical journal

authors： Dawling S,Braithwaite RA,McAuley R,Montgomery SA

更新日期：1980-01-01 00:00:00

abstract：:Most vertebral haemangiomas are asymptomatic. A case of spinal reconstruction for symptomatic extraosseous thoracic haemangioma using a titanium cage is reported. Radiographs of the T11 vertebra demonstrated characteristic vertical striations. Magnetic resonance imaging and computed tomography showed spinal cord compr...

journal_title：Postgraduate medical journal

authors： Ogura T,Mori M,Hayashida T,Osawa T,Hase H

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF STUDY:The aim of the study is to describe the prevalence of illicit drug use in England and Wales using data from the UK Survey of Non-Medical Use of Prescription Drugs (NMURx) programme and to compare against the well-established Crime Survey England and Wales (CSEW). The rationale is that recreational and ...

journal_title：Postgraduate medical journal

authors： Ng FL,Rockhill K,Black J,May KP,Whittington MD,Wood DM,Dargan PI,Green JL

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To audit the current UK outpatient workload and compare this to the national standards as set out by the British Association of Urological Surgeons (BAUS) in A Quality Urological Service for Patients in the New Millennium published in October 2000. PARTICIPANTS:520 UK (NHS) and 21 Republic of Ireland (non-NH...

journal_title：Postgraduate medical journal

authors： Gilmore PE,Shackley DC,Clarke NW,Betts CD,O'Flynn KJ

更新日期：2005-01-01 00:00:00

abstract：:Patients with coronary atherosclerosis present with angina, myocardial infarction and sudden death, most often caused by atherosclerotic stenosis complicated by spasm and/or occlusive thrombosis. All of these events have been shown to exhibit similar diurnal rhythms, with a peak incidence in the morning after waking a...

journal_title：Postgraduate medical journal

authors： Selwyn AP,Raby K,Vita JA,Ganz P,Yeung A

更新日期：1991-01-01 00:00:00

abstract：:Muscarinic receptors are present on several different cells in lung and are predominantly involved in bronchoconstriction and mucus secretion. Muscarinic receptor activation leads to breakdown of phosphoinositides in airway smooth muscle cell membranes, which leads to intracellular calcium release and contraction. Mus...

journal_title：Postgraduate medical journal

authors： Barnes PJ

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Obesity in mid-life may increase the risk of subsequent dementia. Our objective was to study this risk, focusing on differences by age at the time of recording of obesity, in a large defined population. METHODS:A record linkage cohort study was undertaken using national administrative statistical data on hos...

journal_title：Postgraduate medical journal

authors： Wotton CJ,Goldacre MJ

更新日期：2014-10-01 00:00:00

abstract：:Quantitative lipoprotein level data was obtained from healthy subjects and patients with ischaemic heart disease or peripheral vascular disease in four European communities. Hypertriglyceridaemia, due mainly to an increase in VLDL triglyceride, was commoner in London and Uppsala than in Naples and Geneva. In three com...

journal_title：Postgraduate medical journal

authors： Lewis B,Carlson LA,Mancini M,Micheli H

更新日期：1975-01-01 00:00:00

abstract：:This purports to be the first recorded case of carcinoma of the pancreas presenting as a mechanical obstruction of the colon. The literature relating to some other rare modes of presentation is reviewed, and a comment made on the desirability of routine post-mortem studies. ...

journal_title：Postgraduate medical journal

authors： Tresadern JC

更新日期：1981-01-01 00:00:00

abstract：:Functional metastatic adrenocortical carcinoma is an uncommon cause of Cushing's syndrome, which rarely responds to conventional treatment. A patient presenting with Cushing's syndrome secondary to adrenocortical carcinoma underwent surgical resection. Postoperatively, she developed metastatic disease resistant to con...

journal_title：Postgraduate medical journal

authors： Chan NN,Isaacs AJ

更新日期：1999-02-01 00:00:00

abstract：:Spironolactone therapy is a well-known cause of hyperkalaemia, but in susceptible patient, it may also be associated with metabolic acidosis. We report a case of severe renal tubular acidosis (Type IV) with life-threatening hyperkalaemia caused by spironolactone, and discuss the mechanisms by which this may occur. ...

journal_title：Postgraduate medical journal

authors： O'Connell JE,Colledge NR

更新日期：1993-11-01 00:00:00

abstract：:The term "natural childbirth" denotes an approach to childbirth characterised by a bias towards physical and mental hygiene in the management of pregnancy and labour. It emerged in Britain in the interwar period, partly as a response to the growing interventionism of mainstream obstetrics. Its appeal since then has re...

journal_title：Postgraduate medical journal

authors： Moscucci O

更新日期：2003-03-01 00:00:00

abstract：:A study was undertaken to determine the effects of long-term insulin therapy on the development and regression of lipid perturbations and experimental cholesterol atherosclerosis in rabbits: (1) Insulin administration for 15 days significantly reduced plasma lipid levels and free fatty acids in rabbits fed a high-chol...

journal_title：Postgraduate medical journal

authors： Marquié G

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:There are wide variations in survival after cardiopulmonary resuscitation. The aim of this survey was to describe how equipment provision of resuscitation trolleys was deployed in a range of clinical ward areas. METHODS:The equipment in randomly selected resuscitation trolleys in all 14 South West Thames Re...

journal_title：Postgraduate medical journal

authors： Hogh L,Kane I,Bhalla A,Ward MC

更新日期：2005-06-01 00:00:00

abstract：PURPOSE:How medical students learn and develop the characteristics associated with good teaching in medicine is not well known. Information about this process can improve the academic preparation of medical students for teaching responsibilities. The purpose of this study was to determine how different experiences cont...

journal_title：Postgraduate medical journal

authors： Henry BW,Haworth JG,Hering P

更新日期：2006-09-01 00:00:00

abstract：:Using the WHO/ISFC definition and recommendations of nomenclature for cardiomyopathies, the aetiology is unknown. Over many years research has concentrated on defining pathogenetic mechanisms and owing to the widespread use of the bioptome-permitting recovery of fresh endomyocardial tissue-myocarditis has emerged as b...

journal_title：Postgraduate medical journal

authors： Olsen EG

更新日期：1992-01-01 00:00:00

abstract：:About 0.5% of infants are infected in utero with cytomegalovirus (CMV). As many as 20% become mentally retarded and a further substantial proportion suffer lesser degrees of brain damage. The need for a vaccine is greater than in the case of rubella. A live, tissue culture-adapted strain of CMV has been shown to produ...

journal_title：Postgraduate medical journal

authors： Stern H

更新日期：1977-10-01 00:00:00

abstract：PURPOSE OF THE STUDY:Resistin, a recently discovered proinflammatory cytokine, has been strongly linked to kidney dysfunction. The aim of this study was to determine the relationship of serum resistin with serum cystatin C (sCysC) and albuminuria, two sensitive endogenous markers of renal function, in elderly male pati...

journal_title：Postgraduate medical journal

authors： Zhang M,Cui H,Zhu BP,Fu SH

更新日期：2015-03-01 00:00:00

abstract：:Fistulous communications of the uterus are relatively unknown. We report in this paper the first case to our knowledge of uterocutaneous fistula which developed following a septic abortion induced by introduction of Laminaria tent into the uterus. ...

journal_title：Postgraduate medical journal

authors： Gupta SK,Shukla VK,Varma DN,Roy SK

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Workforce studies show a declining proportion of UK junior doctors proceeding directly to specialist training, with many taking career breaks. Doctors may be choosing to delay this important career decision. AIM:To assess doctors' views on the timing of choosing a clinical specialty. METHODS:Surveys of two...

journal_title：Postgraduate medical journal

authors： Lachish S,Goldacre MJ,Lambert TW

更新日期：2018-11-01 00:00:00

abstract：:A case of acute necrotizing pancreatitis in a 53-year-old man with an ectopic adrenocorticotrophin (ACTH) producing bronchial carcinoma is described. The aetiology of acute pancreatitis in relation to steroid therapy and malignancy is discussed and it is suggested that excess endogenous steroid production may also cau...

journal_title：Postgraduate medical journal

authors： Clague HW,Warren B,Krasner N

更新日期：1984-09-01 00:00:00

abstract：:A 72 year old man developed acute myeloblastic leukaemia two years after he had been treated with local curative therapy and chemotherapy for a solitary plasma cytoma of the ilium. ...

journal_title：Postgraduate medical journal

authors： Maharaj D,Dolan G

更新日期：1986-12-01 00:00:00

abstract：:What is the place of medico-historical cases in the professional practice of the disciplinary field of medicine and biology? How can these patients from the past be used for teaching and continuing medical education? How to justify their place in biomedical publications? In this article, we explain all the legitimacy ...

journal_title：Postgraduate medical journal

authors： Charlier P,Donnell S,Lippi D,Nerlich A,Asensi V,Perciaccante A,Appenzeller O,Bianucci R

更新日期：2021-02-01 00:00:00

abstract：:We studied two sisters who developed large non-toxic goitres in adolescence. Deiodinase deficiency was diagnosed by a rapid thyroid uptake of radioactive iodine (RAI) at 2 hours associated with a marked fall in thyroidal 131I by 24 hours. Serial RAI scans in the second patient documented evolution of the iodine-defici...

journal_title：Postgraduate medical journal

authors： Hirsch HJ,Shilo S,Spitz IM

更新日期：1986-06-01 00:00:00

abstract：:The recognition and treatment of depression is a challenging area of clinical practice, especially in primary care where there are many patients with various presentations and a multitude of causes for distress. The prevalence of depression is increasing, and it is predicted to become second only to ischaemic heart di...

journal_title：Postgraduate medical journal

authors： Lester H,Howe A

更新日期：2008-10-01 00:00:00

abstract：:The case of a woman with a large benign villous papilloma of the rectum, presenting with sodium and water depletion and later complicated by persistent hypokalaemia, is described. The patient also suffered from primary hypogonadism and diabetes. ...

journal_title：Postgraduate medical journal

authors： Bamford JK,Galbraith HJ,Pender BW

更新日期：1965-04-01 00:00:00

abstract：:There is considerable evidence to suggest that the identification and treatment of dyslipidaemia will reduce the risk of premature CHD, i.e. before the age of 65. Diagnosis of the cause of raised plasma lipid levels will enable appropriate decisions to be taken with regard to management. The cornerstone of treatment i...

journal_title：Postgraduate medical journal

authors： Betteridge DJ,Dodson PM,Durrington PN,Hughes EA,Laker MF,Nicholls DP,Rees JA,Seymour CA,Thompson GR,Winder AF

更新日期：1993-05-01 00:00:00

abstract：:The differing aspects of fibrocystic disease are presented. The various histological components making up the breast account for the variegated presentation of symptoms and findings. Pain, tenderness and nodularity represent the greatest problem with the former two prompting the patient to seek relief. The latter symp...

journal_title：Postgraduate medical journal

authors： Humphrey LJ,Estes NC

更新日期：1979-01-01 00:00:00

abstract：:A 59 year old woman presented with acute onset of fever, chills, diaphoresis, vague chest discomfort, and was found to be hypotensive and tachypnoeic. An electrocardiogram demonstrated sinoatrial block with a junctional rhythm between 50 and 80 beats/min. All cultures were negative and imaging studies unrevealing. Her...

journal_title：Postgraduate medical journal

authors： Medarov B,Tongia S,Rossoff L

更新日期：2003-11-01 00:00:00

abstract：:Important implications for the recognition of iron deficiency anaemia include diagnosis and correction of underlying causes, most of which are identifiable, in the older patient, by means of conventional upper gastrointestinal endoscopy, and by colonoscopy. The aetiological search may, however, have to be widened to i...

journal_title：Postgraduate medical journal

authors： Jolobe OM

更新日期：2000-04-01 00:00:00