Lack of response to octreotide in Cushing's syndrome due to metastatic adrenocortical carcinoma.

Abstract:

:Functional metastatic adrenocortical carcinoma is an uncommon cause of Cushing's syndrome, which rarely responds to conventional treatment. A patient presenting with Cushing's syndrome secondary to adrenocortical carcinoma underwent surgical resection. Postoperatively, she developed metastatic disease resistant to conventional chemotherapy. Octreotide, a somatostatin analogue which is effective in the treatment of several types of neuroendocrine tumour, was tried to ameliorate her secretory symptoms, but without any therapeutic effect.

journal_name

Postgrad Med J

authors

Chan NN,Isaacs AJ

doi

10.1136/pgmj.75.880.96

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

96-7

issue

880

eissn

0032-5473

issn

1469-0756

journal_volume

75

pub_type

杂志文章
  • Thrombotic thrombocytopenic purpura associated with pregnancy in two sisters.

    abstract::Two sisters suffered from thrombotic thrombocytopenic purpura late in their first pregnancies. HLA typing of the patients and their immediate family members demonstrated no obvious relationship. Hereditary aspects, association with pregnancy, prognosis and management of pregnant women with TTP are discussed. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.69.809.229

    authors: Alqadah F,Zebeib MA,Awidi AS

    更新日期:1993-03-01 00:00:00

  • Delayed sudden death after ingestion of MCPP and ioxynil: an unusual presentation of hormonal weedkiller intoxication.

    abstract::A patient who died in asystole less than 18 h after ingestion of 'Clovercide Extra', a combination hormonal weedkiller containing ioxynil and 4-chloro-2-methyl phenoxypropionic acid, is described. Previous reports describe coma as an early event following ingestion of these herbicides. In contrast our patient, althoug...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.64.755.681

    authors: Dickey W,McAleer JJ,Callender ME

    更新日期:1988-09-01 00:00:00

  • Isolated left ventricular non-compaction: an emerging cause of heart failure in adults.

    abstract::Isolated left ventricular non-compaction is a rare, morphologically distinct primary genetic cardiomyopathy, which was first described in children, but is becoming increasingly recognised in adults. The most common clinical manifestations include heart failure, arrhythmias and embolic events, and in children it may be...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2008.070144

    authors: Nair SB,Khattar RS

    更新日期:2009-04-01 00:00:00

  • A case of myasthenia gravis treated with steroids: some suggestions for the mechanisms underlying their effect.

    abstract::This report deals with a patient with long standing myasthenia gravis treated with a small dose of corticosteroids. The response to treatment was prompt and the post-therapeutic deterioration in function was minimal and cholinergic in nature. It is suggested that the dose of anticholinesterases be reduced concomitantl...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.53.620.321

    authors: Dandona P,Corkan EJ,Sladen GE

    更新日期:1977-06-01 00:00:00

  • Colonoscopy in patients aged 80 years or older and its contribution to the evaluation of rectal bleeding.

    abstract::Colonoscopies performed in patients aged 80 years or older at the Sheba Medical Center were analysed according to the primary indication for the procedure: 101 colonoscopies were performed because of rectal bleeding of at least 2 months duration, and 335 for all other indications. Carcinoma of the large bowel was foun...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.68.799.355

    authors: Bat L,Pines A,Shemesh E,Levo Y,Zeeli D,Scapa E,Rosenblum Y

    更新日期:1992-05-01 00:00:00

  • Alcoholic liver disease.

    abstract::Alcohol is a major cause of liver cirrhosis in the Western world and accounts for the majority of cases of liver cirrhosis seen in district general hospitals in the UK. The three most widely recognised forms of alcoholic liver disease are alcoholic fatty liver (steatosis), acute alcoholic hepatitis, and alcoholic cirr...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pmj.76.895.280

    authors: Walsh K,Alexander G

    更新日期:2000-05-01 00:00:00

  • Changing thyroid status related to pregnancy.

    abstract::A case of post-thyroidectomy hypothyroidism is reported. The patient became euthyroid in three consecutive pregnancies, reverting to hypothyroid within three months of delivery on each occasion. The alteration in thyroid status is attributed to pregnancy related changes in antibody titres, though the laboratory data t...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pmj.77.911.591

    authors: Shankar P,Kilvert A,Fox C

    更新日期:2001-09-01 00:00:00

  • Primary hepatocellular carcinoma associated with Wilson's disease in a young woman.

    abstract::A 27 year old woman with hepato-lenticular degeneration (Wilson's disease) was found to have primary hepatocellular carcinoma (PHC) three and a half years after she was started on treatment with D-penicillamine. The tumour was resected since when she has remained well. Her liver function tests were normal throughout t...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.714.357

    authors: Guan R,Oon CJ,Wong PK,Foong WC,Wee A

    更新日期:1985-04-01 00:00:00

  • Republished review: Surgical management of aortic root disease in Marfan syndrome and other congenital disorders associated with aortic root aneurysms.

    abstract::Elective root replacement in Marfan syndrome has improved life expectancy in affected patients. Three forms of surgery are now available: total root replacement (TRR) with a valved conduit, valve sparing root replacement (VSRR) and personalised external aortic root support (PEARS) with a macroporous mesh sleeve. TRR c...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2013-305132rep

    authors: Treasure T,Takkenberg JJ,Pepper J

    更新日期:2016-02-01 00:00:00

  • Early diffusion weighted imaging and expression of heat shock protein 70 in newborn pigs with hypoxic ischaemic encephalopathy.

    abstract:OBJECTIVE:To establish a cerebral hypoxia ischaemic model in piglets and to explore the early diffusion weighted imaging (DWI) as well as the expression of heat shock protein 70 (HSP70) with hypoxic ischaemic encephalopathy (HIE). METHODS:Twenty four 3 day old piglets were permanently ligated common carotid arteries b...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2004.030114

    authors: Cheng Y,Liu GR,Guan JT,Guo YL,Li YK,Wu RH

    更新日期:2005-09-01 00:00:00

  • Persistent chorea as a manifestation of thyrotoxicosis.

    abstract::We report a case of persistent chorea as a manifestation of thyrotoxicosis. The chorea was severe and persisted after the patient was rendered euthyroid. Dopamine antagonists only partially suppressed the involuntary movements during the first few months. It was eventually controlled with haloperidol, but whenever she...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.64.756.789

    authors: Javaid A,Hilton DD

    更新日期:1988-10-01 00:00:00

  • Defining normal variables of right ventricular size and function in pulmonary hypertension: an echocardiographic study.

    abstract:BACKGROUND:Right ventricular (RV) fractional area change and tricuspid annular plane systolic excursion (TAPSE) are recognised methods for assessing RV function. However, the way in which these variables are affected by varying degrees of pulmonary hypertension (PH) has not been well characterised. METHODS:RV end-syst...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2007.059642

    authors: López-Candales A,Dohi K,Rajagopalan N,Edelman K,Gulyasy B,Bazaz R

    更新日期:2008-01-01 00:00:00

  • Some cardiovascular problems with disopyramide.

    abstract::Five patients with apparent adverse cardiovascular effects of disopyramide are reveiwed. Attention is drawn to the following problems. (1) A vagolytic effect may produce a sinus tachycardia with wide QRS complexes due to aberrant conduction or intraventricular block superficially resembling a ventricular tachycardia, ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.56.654.229

    authors: Warrington SJ,Hamer J

    更新日期:1980-04-01 00:00:00

  • Chronic obstructive pulmonary disease: the clinical management of an acute exacerbation.

    abstract::Exacerbations of chronic obstructive pulmonary disease impose a considerable burden of morbidity, mortality, and health care cost. Management guidelines outlining best practice, based largely on consensus expert opinion, were produced by a number of organisations during the last decade. Current interest in the field i...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2004.019182

    authors: Hurst JR,Wedzicha JA

    更新日期:2004-09-01 00:00:00

  • Eosinophilic fasciitis with pulmonary and pleural involvement.

    abstract::We report a case of eosinophilic fasciitis, with the unusual features of pulmonary and pleural involvement. Similar cases which involve the lungs have been reported after exposure to L-tryptophan, but there is no relevant drug history in this case. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pmj.76.891.36

    authors: Killen JW,Swift GL,White RJ

    更新日期:2000-01-01 00:00:00

  • Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin.

    abstract::We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide. We describe a possible drug interaction between these two drugs and recommend that they should only be used together with c...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.65.770.950

    authors: Webberley MJ,Murray JA

    更新日期:1989-12-01 00:00:00

  • Peliosis of the spleen: possible association with chronic renal failure and erythropoietin therapy.

    abstract::Splenic peliosis was identified at necropsy in a 62-year-old woman receiving continuous ambulatory peritoneal dialysis for end-stage renal failure, and erythropoietin therapy for uraemia and anaemia. The immediate cause of death was arrhythmia related to ischaemic heart disease, following an episode of intramuscular h...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.71.838.493

    authors: Lam KY,Chan AC,Chan TM

    更新日期:1995-08-01 00:00:00

  • Ovarian carcinoma presenting as pyrexia of unknown origin.

    abstract::A patient with a poorly differentiated clear cell adenocarcinoma of the ovary presenting as pyrexia of unknown origin is reported. Following resection of the tumour, her pyrexia resolved completely. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.712.177

    authors: Schofield PM,Kirsop BA,Reginald P,Harington M

    更新日期:1985-02-01 00:00:00

  • Medical and surgical management of priapism.

    abstract::Priapism is a pathological condition of penile erection that persists beyond, or is unrelated to, sexual stimulation. Pathologically and clinically, two subtypes are seen-the high flow (non-ischaemic) variety and the low flow (ischaemic) priapism. The low flow type is more dangerous, as these patients are susceptible ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2005.037291

    authors: Cherian J,Rao AR,Thwaini A,Kapasi F,Shergill IS,Samman R

    更新日期:2006-02-01 00:00:00

  • An audit of "do not attempt resuscitation" decisions in two district general hospitals: do current guidelines need changing?

    abstract:INTRODUCTION:Doctors in all specialties are involved in making "do not attempt resuscitation" (DNAR) decisions; this can be a difficult and challenging process. Guidelines exist to provide an ethical and legal framework for the process and documentation of these decisions. OBJECTIVE:To audit the documentation of resus...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,多中心研究

    doi:10.1136/pgmj.2006.050260

    authors: Harris D,Davies R

    更新日期:2007-02-01 00:00:00

  • Takotsubo cardiomyopathy: a diagnostic challenge.

    abstract::The frequency of the diagnosis of takotsubo cardiomyopathy has increased rapidly over the past few years, possibly due to increasing awareness among cardiologists. At initial presentation the diagnosis remains a challenge because of the close similarity between the presentation of takotsubo cardiomyopathy, and that of...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2010.102475

    authors: Zeb M,Sambu N,Scott P,Curzen N

    更新日期:2011-01-01 00:00:00

  • Clinical distinction of cerebral haemorrhage and cerebral infarction.

    abstract::The clinical features of 62 cases of computerized axial tomography scan-proved cerebral haemorrhage and 81 cases of cerebral infarction in the carotid territory have been compared in a retrospective case note survey. The clinical features which can help in making the distinction between haemorrhage and infarction at t...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.56.659.629

    authors: Harrison MJ

    更新日期:1980-09-01 00:00:00

  • Camel bites: report of severe osteolysis as late bone complications.

    abstract::Four cases of severe osteolysis of bones subsequent to camel bite are described. The first had osteolysis of the ribs with traumatic diaphragmatic hernia. Two cases had similar appearances of gross osteolysis of the shafts of the radius and ulna, whilst one had osteolysis of the humeral shaft. The similarities in the ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.65.770.900

    authors: al-Boukai AA,Hawass NE,Patel PJ,Kolawole TM

    更新日期:1989-12-01 00:00:00

  • Prognostic indicators and generation of novel risk equations for estimation of 10-year and 20-year mortality following acute coronary syndrome.

    abstract:OBJECTIVES:Although risk assessment is an integral part of management, there are currently no risk calculators of long-term mortality after acute coronary syndrome (ACS). The aim was to provide risk equations for 10-year and 20-year mortality following ACS. METHODS:Patients hospitalised with ACS from December 1990 to ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2016-134129

    authors: Magri CJ,Debono R,Calleja N,Galea J,Fava S

    更新日期:2017-05-01 00:00:00

  • Effect of tricyclic antidepressants on analgesic activity in laboratory animals.

    abstract::A study has been made in rodents of the interactions between a range of psychotropic drugs, narcotic agonist and partial agonist analgesics, and pain. In rodents, tricyclic antidepressants do not alone reduce pain responses but, in combination with morphine or pentazocine, clomipramine enhances analgesic activity afte...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:

    authors: Lee RL,Spencer PS

    更新日期:1980-01-01 00:00:00

  • Birmingham Medical Research Expeditionary Society 1977 Expedition: effect of a Himalayan trek on whole body composition, nitrogen and potassium.

    abstract::The body composition of the 17 members of the BMRES was studied using body weight and fat fold calipers, with measurements of whole body potassium and nitrogen. The full assessment was made just before departure from Birmingham and immediately on return. Daily observations of body weight and fat folds were made during...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.55.645.475

    authors: Harvey TC,James HM,Chettle DR

    更新日期:1979-07-01 00:00:00

  • Congestive cardiomyopathy and endobronchial granulomas as manifestations of Churg-Strauss syndrome.

    abstract::Churg-Strauss syndrome is a systemic vasculitis. Its most frequent complications are heart diseases and asthma. Usually, cardiological manifestations are pericarditis, cardiac failure and myocardial infarction. Endobronchial granulomas identified by bronchoscopy are unusual. We present the case of a man with congestiv...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.71.836.365

    authors: Alvarez-Sala R,Prados C,Armada E,Del Arco A,Villamor J

    更新日期:1995-06-01 00:00:00

  • 'Epidemic neuromyasthenia' in Southwest Ireland.

    abstract::During the course of an obscure illness in a teenage girl it was eventually realized that the diagnosis was 'epidemic neuromyasthenia'. The illness which occurred between February and September 1976 was characterized by fatigue, pallor, headache, nuchal pain, alterations in mentation, dizziness, nausea and vomiting, p...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.54.637.731

    authors: Corridan JP

    更新日期:1978-11-01 00:00:00

  • Acquired common variable hypogammaglobulinaemia and lymphoedema.

    abstract::Two patients with lymphoedema of the legs developed recurrent respiratory infections and were found to have panhypogammaglobulinaemia. The early recognition and treatment of this form of immunity deficiency in patients with lymphoedema is important in order to prevent recurrent infections which could cause pulmonary d...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.64.747.63

    authors: Lozewicz S,Morris G,Garbett N,Browse N,Slavin B,Cole P

    更新日期:1988-01-01 00:00:00

  • Acute transverse myelopathy complicating tetanus.

    abstract::A 12-year-old boy presented with typical features of short incubation tetanus. Spastic paraparesis with a mid-thoracic sensory level was present from the time of the initial examination. X-rays of the spine and lumbar myelogram were normal. The paraparesis improved rapidly and within a month the patient was free of ne...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.57.669.443

    authors: Bahemuka M

    更新日期:1981-07-01 00:00:00