Acute transverse myelopathy complicating tetanus.

abstract：:The majority of second-generation calcium antagonists are dihydropyridines, some of which show vascular selectivity. Several new dihydropyridines have been developed with comparable pharmacodynamic properties to existing calcium antagonists in this class and greatly improved kinetic half-lives. Of these agents, amlodi...

journal_title：Postgraduate medical journal

authors： Opie LH

更新日期：1991-01-01 00:00:00

abstract：:Metabolic acidosis and hyperlactataemia are important, independent findings in acute illness, and the combination of these abnormalities carries a grave prognosis. Despite this there is still controversy about the most appropriate therapy of lactic acidosis, and the relationship of commonly used acid base measurements...

journal_title：Postgraduate medical journal

authors： Nimmo GR,Grant IS,Mackenzie SJ

更新日期：1991-01-01 00:00:00

abstract：:Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical ...

journal_title：Postgraduate medical journal

authors： Mahy IR,Jennings KP

更新日期：1998-06-01 00:00:00

abstract：:Digital clubbing has been a well recognised feature of several distinct clinical conditions, including respiratory, cardiac, and gastrointestinal diseases since the Hippocratic era. However, clubbing associated with Behçet's disease has not been reported before. We describe a case of clubbing in a young man with Behçe...

journal_title：Postgraduate medical journal

authors： Benekli M,Güllü IH

更新日期：1997-09-01 00:00:00

abstract：:A 56 year old man presented with an atypical chest infection. Remote inferoposterior myocardial infarction was noted on electrocardiography and transthoracic echocardiography. Hepatic failure developed with sudden gross elevation of liver aminotransferases and coagulopathy. No primary hepatic cause could be identified...

journal_title：Postgraduate medical journal

authors： Szawarski P,Sensky PR,Doshi M,Hudson I

更新日期：2004-09-01 00:00:00

abstract：:We present a 78-year-old woman with clinical acute hypopituitarism in whom pathologic findings showed lymphocytic hypophysitis and retroperitoneal fibrosis. Lymphocytic hypophysitis should be included in the differential diagnosis of hypopituitarism at any age. The association with idiopathic retroperitoneal fibrosis ...

journal_title：Postgraduate medical journal

authors： Alvarez A,Cordido F,Sacristán F

更新日期：1997-11-01 00:00:00

abstract：:The anaesthetic properties of propofol ('Diprivan') have been described previously. This report summarizes additional studies designed to investigate some aspects of the general pharmacology of propofol. Following recovery from anaesthesia with propofol there was no evidence of any central anticholinergic or anticonvu...

journal_title：Postgraduate medical journal

authors： Glen JB,Hunter SC,Blackburn TP,Wood P

更新日期：1985-01-01 00:00:00

abstract：:The reported impact of human monoclonal IgM antibody (HA1A) on the mortality rate from Gram-negative bacteraemia aroused considerable interest in its use in Glasgow Royal Infirmary. However, the commercial preparation of HA1A was extremely expensive. With this in mind, the Infirmary's Drugs and Therapeutics Committee ...

journal_title：Postgraduate medical journal

authors： Bell E,McCartney C

更新日期：1995-02-01 00:00:00

abstract：:A previously healthy 17 year old boy had Staphylococcus aureus endocarditis presenting as acute scrotal pain. There was no trauma or evidence of scrotal or epididymal infection. The pain subsided after therapy for endocarditis was started. ...

journal_title：Postgraduate medical journal

authors： Watanakunakorn C

更新日期：1987-07-01 00:00:00

abstract：:Three patients are described in whom one or more carotid territory transient ischaemic attacks (TIAs) were preceded by sneezing, straining, or bending over. It is argued that the mechanism involved dislodgment of embolic material from the site of carotid atheroma. This mechanism should be considered as an alternative ...

journal_title：Postgraduate medical journal

authors： Harrison MJ

更新日期：1999-03-01 00:00:00

abstract：:A patient is described who developed mild hyponatraemia on two occasions when treated with bendrofluazide alone, but severe hyponatraemia when treated with the combination of enalapril and bendrofluazide. ...

journal_title：Postgraduate medical journal

authors： Collier JG,Webb DJ

更新日期：1987-12-01 00:00:00

abstract：:Heart failure is a major problem worldwide; it is the leading cause of hospitalisation and is posing a huge financial burden. Advances in healthcare have contributed to increased life expectancy, with a resultant increase in the number of patients with chronic heart failure. For many patients who are still severely sy...

journal_title：Postgraduate medical journal

authors： Patel S,Nicholson L,Cassidy CJ,Wong KY

更新日期：2016-05-01 00:00:00

abstract：:This paper reviews the adverse events reported by 12,917 patients treated with cephalexin in formal clinical trials. Six percent of all patients reported adverse events, and in 3% the association with the drug was thought to be definite or probable. In the remaining 3%, the relationship was uncertain. The gastrointest...

journal_title：Postgraduate medical journal

authors： Burt RA

更新日期：1983-01-01 00:00:00

abstract：:Candida albicans peritonitis developed in a 48-year-old man with a perforated gastric ulcer who subsequently was treated with intravenous amphotericin B. The drug penetrated well into the inflamed peritoneal cavity and eradicated the organism from the peritoneal fluid. Nevertheless, at post-mortem, Candida organisms w...

journal_title：Postgraduate medical journal

authors： Peterson LR,Kelty RH,Hall WH,Votava HJ

更新日期：1978-05-01 00:00:00

abstract：:There is evidence that acetylcholine antagonists at the neuromuscular junction and elsewhere can act by blocking the ionic channels opened by acetylcholine as well as by competing with acetylcholine for receptor sites. This type of uncompetitive antagonism can be distinguished from competitive antagonism in various wa...

journal_title：Postgraduate medical journal

authors： Rang HP

更新日期：1981-01-01 00:00:00

abstract：:The gross and microscopic features of an unusual case of neurocutaneous melanosis are described. This is an example of the rare association between a primary central nervous system malignant melanoma and a giant congenital melanocytic naevus of 'bathing trunk' distribution. ...

journal_title：Postgraduate medical journal

authors： Salisbury JR,Rose PE

更新日期：1989-06-01 00:00:00

abstract：:The differing aspects of fibrocystic disease are presented. The various histological components making up the breast account for the variegated presentation of symptoms and findings. Pain, tenderness and nodularity represent the greatest problem with the former two prompting the patient to seek relief. The latter symp...

journal_title：Postgraduate medical journal

authors： Humphrey LJ,Estes NC

更新日期：1979-01-01 00:00:00

abstract：:A 46 year old woman presented with the CREST variety of systemic sclerosis and occult gastrointestinal bleeding due to vascular malformations of her stomach. Partial gastrectomy cured her anaemia. In systemic sclerosis, visceral angiography should be performed early when initial investigations have been negative. ...

journal_title：Postgraduate medical journal

authors： el-Omar MM,Jenkins AP,Hollowood K,Banerjee AK,Thompson RP

更新日期：1994-04-01 00:00:00

abstract：:The role of prostaglandins in inflammation is still disputed. Some workers have attempted to fit prostaglandins into a simple model, i.e. inflammatory leads to chemical mediator leads to vascular response. Recent work has shown that this approach may be misleading. An alternative model is proposed, involving the inter...

journal_title：Postgraduate medical journal

authors： Williams TJ

更新日期：1977-11-01 00:00:00

abstract：:We describe the case of an acromegalic woman with primary infertility who was treated with clomiphene, and subsequently developed pituitary apoplexy. ...

journal_title：Postgraduate medical journal

authors： Walker AB,Eldridge PR,MacFarlane IA

更新日期：1996-03-01 00:00:00

abstract：:Haemorrhage of small bowel origin may prove to be a clinical and diagnostic challenge, particularly when the bleeding is massive and continuous. Such a case is described where the source of blood loss was a jejunal vascular abnormality. ...

journal_title：Postgraduate medical journal

authors： Saunders MP

更新日期：1991-07-01 00:00:00

abstract：:Sudden cardiac death is the leading cause of mortality among young athletes with an incidence of 1-2 per 100,000 athletes per annum. It is described as 'an event that is non-traumatic, non-violent, unexpected, and resulting from sudden cardiac arrest within six hours of previously witnessed normal health'. Most predis...

journal_title：Postgraduate medical journal

authors： Pugh A,Bourke JP,Kunadian V

更新日期：2012-07-01 00:00:00

abstract：:Mild and self-limiting fever following bleomycin use is common, and a fatal hyperpyrexial response occurs rarely. In previously reported cases, such hyperpyrexia occurred either after the initial administration of the drug or during subsequent therapy following an initial pyrexial response. We describe a fatal hyperpy...

journal_title：Postgraduate medical journal

authors： Leung WH,Lau JY,Chan TK,Kumana CR

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:Effective communication is a vital part of good clinical care. Traditionally bleep systems have been used as the mainstay of communication. Mobile technology is increasingly seen as a quicker, easier and more reliable method of communication. Our objective was to assess the use of mobile devices within a typ...

journal_title：Postgraduate medical journal

authors： Martin G,Janardhanan P,Withers T,Gupta S

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Despite the importance of timely management of patients with inflammatory arthritis (IA), delays exist in its diagnosis and treatment. OBJECTIVE:To perform a systematic literature review to identify strategies addressing these delays to inform an American College of Rheumatology (ACR)/European League Agains...

journal_title：Postgraduate medical journal

authors： Villeneuve E,Nam JL,Bell MJ,Deighton CM,Felson DT,Hazes JM,McInnes IB,Silman AJ,Solomon DH,Thompson AE,White PH,Bykerk VP,Emery P

更新日期：2013-04-01 00:00:00

abstract：:The majority of deaths in COPD are from cardiovascular causes. Several large randomized controlled trials demonstrate that inhaled anticholinergic agents ipratropium and tiotropium increase the risk of serious cardiovascular events, including cardiovascular mortality. Tiotropium Respimat is associated with a statistic...

journal_title：Postgraduate medical journal

authors： Singh S,Loke YK,Enright P,Furberg CD

更新日期：2014-04-01 00:00:00

abstract：:The clinical significance of the abnormalities seen at left ventriculography in ischaemic heart disease is discussed. Aneurysms may be recognized when left ventriculography is combined with coronary arteriography to show the characteristic obliteration of the supplying artery. Localized areas of abnormal contraction s...

journal_title：Postgraduate medical journal

authors： Khattri HN,Raphael MJ,Sharma B,Steiner RE,Goodwin JF

更新日期：1978-01-01 00:00:00

abstract：:This study examines clinical features of late onset anorexia nervosa. This involved the scrutiny of a large database of patients with anorexia nervosa comprising data gathered at standardized initial assessments over the period 1960-1990. Patients with a late onset were compared to other selected patient samples. The ...

journal_title：Postgraduate medical journal

authors： Joughin NA,Crisp AH,Gowers SG,Bhat AV

更新日期：1991-11-01 00:00:00

abstract：:The introduction of spiral technology to computed tomography (CT) scanners in the late 1980s has revolutionised the field of CT. Spiral CT offers definite practical benefits over conventional scanners and has expanded the role of CT through the development of new scanning techniques. CT scanning now rivals magnetic re...

journal_title：Postgraduate medical journal

authors： Kearney SE,Garvey CJ

更新日期：1998-02-01 00:00:00

abstract：PURPOSE:The WHO estimates that by 2020 two-thirds of the diseases worldwide will be the result of unhealthy lifestyle habits. Less than half of primary care physician graduates feel prepared to give lifestyle behaviour counselling. Our objective was to evaluate the impact of lifestyle medicine (LM) course on self-repor...

journal_title：Postgraduate medical journal

authors： Malatskey L,Bar Zeev Y,Tzuk-Onn A,Polak R

更新日期：2017-09-01 00:00:00