Republished: pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications.

abstract：:We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement. Some dangers of this therapy and necessary precautions ...

journal_title：Postgraduate medical journal

authors： Burns A,Brown TM,Semple P

更新日期：1983-08-01 00:00:00

abstract：:Five cases of strangulated femoral hernia, all with a delay in establishing the diagnosis, are reported here. These cases illustrate the continuing difficulties experienced, both in primary care and hospital practice, in making this diagnosis despite the clinical awareness of this condition. ...

journal_title：Postgraduate medical journal

authors： Heys SD,Brittenden J

更新日期：1991-01-01 00:00:00

abstract：:A case of Peutz-Jeghers syndrome with polyps in the gall bladder is presented. No previous description of this finding has been reported. The literature regarding known sites of polyposis in this condition is reviewed. ...

journal_title：Postgraduate medical journal

authors： Foster DR,Foster DB

更新日期：1980-05-01 00:00:00

abstract：:Prolonged coma resulting from hypoxic brain injury is usually associated with a dismal chance of return to independent existence. In this report a case is described of a 60 year old man who recovered and returned to work as a university professor after being in a vegetative state at least 8 weeks after a prolonged cer...

journal_title：Postgraduate medical journal

authors： Falk RH

更新日期：1990-05-01 00:00:00

abstract：:We describe two patients with diabetes mellitus and associated neuropathy, who presented with painless foot swelling and no history of trauma. X-Rays revealed recent underlying fractures-in one of a metatarsus, and the other of a proximal phalanx. These were assumed to be 'stress' fractures unassociated with pain beca...

journal_title：Postgraduate medical journal

authors： Gill G,Benbow S,Tesfaye S,Kaczmarczyk E,Kaye L

更新日期：1997-04-01 00:00:00

abstract：:Fifteen patients who had undergone a 14 inches X 4 inches jejuno-ileal bypass operation for obesity, 3 to 4 years earlier, were investigated by iliac bone biopsy, radiology and routine biochemistry, including 25-hydroxy-vitamin D and parathyroid hormone estimations. Two patients had histological osteomalacia which was...

journal_title：Postgraduate medical journal

authors： Gilmore IT,Eastwood JB,Ellis WR,Luck VA,Fenton S,O'Grady AJ,Harris E,Murray-Lyon IM

更新日期：1983-05-01 00:00:00

abstract：:Exacerbations of chronic obstructive pulmonary disease impose a considerable burden of morbidity, mortality, and health care cost. Management guidelines outlining best practice, based largely on consensus expert opinion, were produced by a number of organisations during the last decade. Current interest in the field i...

journal_title：Postgraduate medical journal

authors： Hurst JR,Wedzicha JA

更新日期：2004-09-01 00:00:00

abstract：:The causes of death, as determined by autopsy, in 10 patients dying from the acute effects of phaeochromocytoma were myocardial infarction (five patients), left ventricular failure (two patients), cerebral haemorrhage (two patients) and circulatory collapse with malignant phaeochromocytoma (one patient). Most patients...

journal_title：Postgraduate medical journal

authors： Cohen CD,Dent DM

更新日期：1984-02-01 00:00:00

abstract：:A patient with calcific constrictive pericarditis due to rheumatoid arthritis is presented: the literature reveals only one previous case which was attributed to the long duration of the rheumatoid arthritis. ...

journal_title：Postgraduate medical journal

authors： Manji H,Raven P

更新日期：1990-01-01 00:00:00

abstract：:A patient with acute lymphoblastic leukaemia who developed ovarian and uterine leukaemic relapse while in bone marrow remission is described. Pelvic relapse is rarely reported during the clinical course of leukaemia in females. Pelvic ultrasonography, a non-invasive procedure, was of value as an aid in detecting pelvi...

journal_title：Postgraduate medical journal

authors： Cantwell B,Cantwell D,Fennelly JJ

更新日期：1982-11-01 00:00:00

abstract：:The recognition and treatment of depression is a challenging area of clinical practice, especially in primary care where there are many patients with various presentations and a multitude of causes for distress. The prevalence of depression is increasing, and it is predicted to become second only to ischaemic heart di...

journal_title：Postgraduate medical journal

authors： Lester H,Howe A

更新日期：2008-10-01 00:00:00

abstract：:Two patients with sarcoidosis and glomerular mesangial proliferative lesions are described. Although a causative relationship between sarcoidosis and glomerulonephritis has been suggested, critical review of the literature fails to confirm this. ...

journal_title：Postgraduate medical journal

authors： Howard RS,Gabriel R

更新日期：1992-03-01 00:00:00

abstract：:Although many of the fundamental biological features of toxoplasmosis are today well appreciated, the practical problem of prevention of its most serious consequence--disabling congenital disease, remains unsolved. The reasons vary in different communities, but are concerned with detection of the chief mode of spread,...

journal_title：Postgraduate medical journal

authors： Williams H

更新日期：1977-10-01 00:00:00

abstract：:Hospital referral is indicated as an emergency for breast infections not settling with oral antibiotics. Referrals to a breast clinic over a period of 6 months were assessed for prior antibiotic prescription. A total of 1078 patients were seen during this period. 91 (8%) patients had been prescribed antibiotics, 71% o...

journal_title：Postgraduate medical journal

authors： Twine C,Gateley CA

更新日期：2006-11-01 00:00:00

abstract：:Repeated pneumonia and hypogammaglobulinaemia was associated with long term low dose steroid therapy. Clinical improvement with restoration of antibody levels followed substitution of aerosol for oral therapy. ...

journal_title：Postgraduate medical journal

authors： Lee RJ,Fay AC

更新日期：1985-06-01 00:00:00

abstract：:The selective COX-2 inhibitors (coxibs) were originally developed to minimise the adverse effects of conventional non-steroidal anti-inflammatory drugs (NSAIDs) while maintaining the same analgesic and anti-inflammatory properties. Many large studies confirmed the improved gastric side effect profile of coxibs compare...

journal_title：Postgraduate medical journal

authors： Sooriakumaran P

更新日期：2006-04-01 00:00:00

abstract：AIM:Leptin, synthesised by adipocytes, has been identified as a hormone that can influence inflammatory activity. Several studies have investigated leptin levels in patients with multiple sclerosis (MS), but the results are not consistent. This study aims to derive a more precise evaluation on the relationship between ...

journal_title：Postgraduate medical journal

authors： Xie XF,Huang XH,Shen AZ,Li J,Sun YH

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Patients with irreversible chronic kidney disease who require dialysis immediately are a subset of ultra late referrals for whom the term chronic kidney disease presenting acutely might usefully be applied. Although well known to nephrologists and recognised as a specific group with considerable problems, li...

journal_title：Postgraduate medical journal

authors： Wolfe M,Almond A,Robertson S,Donaldson K,Isles C

更新日期：2010-07-01 00:00:00

abstract：:Muscarinic receptors are present on several different cells in lung and are predominantly involved in bronchoconstriction and mucus secretion. Muscarinic receptor activation leads to breakdown of phosphoinositides in airway smooth muscle cell membranes, which leads to intracellular calcium release and contraction. Mus...

journal_title：Postgraduate medical journal

authors： Barnes PJ

更新日期：1987-01-01 00:00:00

abstract：:Isolated left ventricular non-compaction is a rare, morphologically distinct primary genetic cardiomyopathy, which was first described in children, but is becoming increasingly recognised in adults. The most common clinical manifestations include heart failure, arrhythmias and embolic events, and in children it may be...

journal_title：Postgraduate medical journal

authors： Nair SB,Khattar RS

更新日期：2009-04-01 00:00:00

abstract：:We report the case of a young man with Fusobacterium necrophorum meningitis who developed bilateral carotid artery stenosis associated with thrombosis of the cavernous sinuses. Intraluminal clot was present in the region of the stenoses for which he was anticoagulated. The clinical presentation, problems with diagnosi...

journal_title：Postgraduate medical journal

authors： Jones TH,Bergvall V,Bradshaw JP

更新日期：1990-09-01 00:00:00

abstract：:The marked decline in coronary heart disease mortality in the United States since the late 1960s is most likely due in large part to successful efforts at primary prevention, attributable in turn to improved eating habits, better control of blood pressure and a reduction in smoking. Another part of the decline can pro...

journal_title：Postgraduate medical journal

authors： Epstein FH

更新日期：1984-01-01 00:00:00

abstract：:Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies...

journal_title：Postgraduate medical journal

authors： McAlister FA,Teo KK

更新日期：1997-04-01 00:00:00

abstract：:In a routine adult gastroenterological practice, seventeen (15%) of 123 patients had small-intestinal biopsies which were neither normal nor were completely flat as found in classical coeliac disease. Some of these had a possible cause for the mild mucosal abnormality, but in six there was no other apparent cause and ...

journal_title：Postgraduate medical journal

authors： Scott BB,Losowsky MS

更新日期：1977-03-01 00:00:00

abstract：:Two cases of pubic osteomyelitis presenting as a painful hip are reported. In both cases the diagnosis was delayed by the unusual presentation and by the limited radiological investigation. Pubic osteomyelitis is rare in childhood but should be considered in the differential diagnosis of the 'irritable hip'. ...

journal_title：Postgraduate medical journal

authors： Weinberg JR,Berman L,Dootson G,Mitchell R

更新日期：1987-04-01 00:00:00

abstract：:Although primary percutaneous coronary intervention (PCI) in clinical trials has lower rates of reinfarction, stroke and mortality than fibrinolytic therapy, because of system delays in routine practice, field triage and prehospital administration of fibrinolytic therapy may lead to similar clinical outcomes, especial...

journal_title：Postgraduate medical journal

authors： Edmond JJ,Juergens CP,French JK

更新日期：2009-06-01 00:00:00

abstract：:Gastric outlet obstruction by gall stone is a rare complication of a common disorder. Two cases are reported here. The investigations are conducted along the same lines as for pyloric stenosis. The diagnosis can be made with a barium meal or gastroscopy. Treatment is by surgical intervention after adequate resuscitati...

journal_title：Postgraduate medical journal

authors： Ah-Chong K,Leong YP

更新日期：1987-10-01 00:00:00

abstract：PURPOSE OF THE STUDY:Grit is characterised by the ability to persevere during difficulties and maintain a sustained effort over an extended period of time. Throughout their careers, doctors will experience many periods of stress and difficulty. This may result in burnout, defined by the presence of exhaustion and disen...

journal_title：Postgraduate medical journal

authors： Halliday L,Walker A,Vig S,Hines J,Brecknell J

更新日期：2017-07-01 00:00:00

abstract：:Three patients with Crohn's disease are described who were treated by ileal resection for intestinal obstruction. Histological examination of the resected specimen in each case established the diagnosis of adenocarcinoma of the small intestine complicating Crohn's disease. This diagnosis should be considered in patien...

journal_title：Postgraduate medical journal

authors： Gillen CD,Wilson CA,Walmsley RS,Sanders DS,O'Dwyer ST,Allan RN

更新日期：1995-03-01 00:00:00

abstract：:Treatment of angina with a single drug often proves unsatisfactory because of dose-related unwanted effects or occasionally an adverse effect on the angina. A combination of a beta-blocking agent and a calcium antagonist drug might achieve satisfactory control of angina at acceptable doses of each drug. Widespread app...

journal_title：Postgraduate medical journal

authors： Geddes JS

更新日期：1983-01-01 00:00:00