Bone disease after jejuno-ileal bypass for morbid obesity.

Abstract:

:Fifteen patients who had undergone a 14 inches X 4 inches jejuno-ileal bypass operation for obesity, 3 to 4 years earlier, were investigated by iliac bone biopsy, radiology and routine biochemistry, including 25-hydroxy-vitamin D and parathyroid hormone estimations. Two patients had histological osteomalacia which was mild in one. A further 9 patients had abnormal bone biopsies, there being an excess of trabecular bone surface covered by osteoid with a normal or reduced amount of calcification front. Six of these 9 showed an increase in trabecular resorption, although in none were there excessive numbers of osteoclasts. The likely explanation for these findings is that these 9 patients had early osteomalacia with mild hyperparathyroidism, making a total of 11 patients out of 15 with osteomalacia. Radiology and blood chemistry were poor predictors of histological bone disease.

journal_name

Postgrad Med J

authors

Gilmore IT,Eastwood JB,Ellis WR,Luck VA,Fenton S,O'Grady AJ,Harris E,Murray-Lyon IM

doi

10.1136/pgmj.59.691.299

subject

Has Abstract

pub_date

1983-05-01 00:00:00

pages

299-303

issue

691

eissn

0032-5473

issn

1469-0756

journal_volume

59

pub_type

杂志文章
  • A comparison of beclomethasone dipropionate aqueous nasal spray and beclomethasone dipropionate pressurized nasal spray in the management of seasonal rhinitis.

    abstract::Forty patients with seasonal rhinitis and a proven sensitivity to pollens were studied for 2 weeks during the pollen season of 1982. The study was carried out according to a double-blind, double-dummy design. All patients received 100 micrograms beclomethasone dipropionate (BDP) into each nostril twice daily (400 micr...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/pgmj.60.704.404

    authors: Dunn AM,Wilson RS,Baggott PJ

    更新日期:1984-06-01 00:00:00

  • Subendocardial infarction and thrombocytopenia.

    abstract::Two female patients who suffered from drug-induced thrombocytopenic purpura and subendocardial myocardial infarction are presented. One of them died from cerebral haemorrhage and diffuse subendocardial punctate haemorrhages were found at post-mortem. The abnormal haemostasis which is associated with thrombocytopenia m...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.55.639.36

    authors: Fireman Z,Yust I,Zahavi J,Kahn Y,Abramov LA

    更新日期:1979-01-01 00:00:00

  • Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome?

    abstract::Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised as a major public health burden. Large-scale epidemiological studies have demonstrated an independent relationship between OSAS and various cardiovascular disorders. The pathogenesis of cardiovascular complications in OSAS is not ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/thx.2008.105577

    authors: Ryan S,Taylor CT,McNicholas WT

    更新日期:2009-12-01 00:00:00

  • Venepuncture: the medicolegal hazards.

    abstract::Venepuncture is commonly regarded as a trivial procedure allocated to the most junior medical staff. The result of this policy is that junior doctors are required to perform a minimally invasive procedure on consenting patients without any structured venepuncture training or assessment. Consequently, inexperienced doc...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.72.843.23

    authors: McConnell AA,Mackay GM

    更新日期:1996-01-01 00:00:00

  • Exercise and hormonal secretion.

    abstract::The effect of graded exercise on the secretion of cortisol, testosterone, prolactin, growth hormone, thyroid stimulating hormone (TSH), luteinizing hormone and follicle stimulating hormone (FSH) is reported. While cortisol, prolactin, growth hormone and testosterone rise during the period of exercise, a rise in lutein...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.55.644.373

    authors: Gawel MJ,Park DM,Alaghband-Zadeh J,Rose FC

    更新日期:1979-06-01 00:00:00

  • Cerebral neoplastic angioendotheleosis complicated by hypercalcaemia.

    abstract::This is a case report of a 67 year old man who presented with a fluctuating level of consciousness and myoclonic jerks caused in part by hypercalcaemia. The diagnosis of cerebral neoplastic angioendotheleosis was only made later on brain biopsy and is the first report of the occurrence of hypercalcaemia in neoplastic ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.67.788.571

    authors: Wierzbicki AS,Gibbs JM,Lidov HG,Lolin Y,Thomas PK

    更新日期:1991-06-01 00:00:00

  • Effect of nivazol in Nelson's syndrome.

    abstract::We report the use of nivazol in a patient with Nelson's syndrome. Nivazol was highly effective in reducing ACTH secretion but, contrary to reports of its use in other primates, in our patient nivazol did have systemic glucocorticoid effects. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.64.749.220

    authors: Ball JA,Williams G,Yeo TH,Joplin GF

    更新日期:1988-03-01 00:00:00

  • Calcific constrictive pericarditis due to rheumatoid arthritis.

    abstract::A patient with calcific constrictive pericarditis due to rheumatoid arthritis is presented: the literature reveals only one previous case which was attributed to the long duration of the rheumatoid arthritis. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.66.771.57

    authors: Manji H,Raven P

    更新日期:1990-01-01 00:00:00

  • The presentation, diagnosis and treatment of cervical osteoid osteoma.

    abstract::A case of cervical osteoid osteoma is reported, with a brief account of the diagnosis and treatment of these lesions. Cervical osteoid osteoma is rare but its pattern of presentation varies little and it should therefore be possible to suspect it on clinical grounds alone. Bone scanning is now regarded as more efficie...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.56.660.724

    authors: Walker AP

    更新日期:1980-10-01 00:00:00

  • Clinicolaboratory profile of 33 Arabs with systemic lupus erythematosus.

    abstract::A clinical and laboratory survey of systemic lupus erythematosus was conducted in 33 Arab patients in the UAE. Arthropathy (91%) followed by renal involvement (54%) and haematological disorders (45.5%) were the major clinical manifestations. Discoid rash (3%) was the least common. Apart from headaches, other neuropsyc...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.72.853.677

    authors: al-Attia HM

    更新日期:1996-11-01 00:00:00

  • Uterine and ovarian leukaemic relapse during bone marrow remission in acute lymphoblastic leukaemia.

    abstract::A patient with acute lymphoblastic leukaemia who developed ovarian and uterine leukaemic relapse while in bone marrow remission is described. Pelvic relapse is rarely reported during the clinical course of leukaemia in females. Pelvic ultrasonography, a non-invasive procedure, was of value as an aid in detecting pelvi...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.58.685.724

    authors: Cantwell B,Cantwell D,Fennelly JJ

    更新日期:1982-11-01 00:00:00

  • Anabolic steroid induced hypogonadism treated with human chorionic gonadotropin.

    abstract::A case is presented of a young competitive body-builder who abused anabolic steroid drugs and developed profound symptomatic hypogonadotrophic hypogonadism. With the help of prescribed testosterone (Sustanon) he stopped taking anabolic drugs, and later stopped Sustanon also. Hypogonadism returned, but was successfully...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.74.867.45

    authors: Gill GV

    更新日期:1998-01-01 00:00:00

  • Lymphoplasmacytoid lymphoma elaborating lambda chain paraprotein with amyloid deposition in Sjögren's syndrome.

    abstract::A woman presented with painful enlargement of her parotid and submandibular glands. She was shown to have the previously unreported combination of idiopathic thrombocytopenic purpura, Sjögren's syndrome, Hashimoto's disease, and myasthenia gravis. Parotid gland biopsy and bone marrow examination showed the presence of...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.65.763.323

    authors: Savage AW,Shareef DS,Maher EJ,Bennett MH,Thomas DJ

    更新日期:1989-05-01 00:00:00

  • Simple techniques to treat medical phobias.

    abstract::Participant modelling, a behaviourally-orientated treatment technique, is an effect method of treating phobias associated with minor medical procedures or apparatus such as needles or intravenous catheters. The steps in this technique are described and two cases of severe needle phobias successfully treated with parti...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.53.615.28

    authors: Taylor CB,Ferguson JM,Wermuth BM

    更新日期:1977-01-01 00:00:00

  • Acanthosis nigricans: relation with type 2 diabetes mellitus, anthropometric variables, and body mass in Indians.

    abstract:OBJECTIVE:To determine the prevalence of acanthosis nigricans (AN) in type 2 diabetes mellitus (T2DM) and its correlation with various anthropometric measurements in Indians. METHODS:One hundred and fifty consecutive subjects with T2DM attending the diabetes clinic at a tertiary referral centre in North India were con...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2004.028308

    authors: Grandhe NP,Bhansali A,Dogra S,Kumar B

    更新日期:2005-08-01 00:00:00

  • The use of erythropoietin in renal failure.

    abstract::The treatment of renal anaemia by recombinant human erythropoietin (EPO) is now well established. Several studies have examined the pharmacokinetics and efficacy of the drug given intravenously, intraperitoneally and subcutaneously and there is increasing evidence that the subcutaneous route has several advantages inc...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.67.783.9

    authors: Macdougall IC,Hutton RD,Coles GA,Williams JD

    更新日期:1991-01-01 00:00:00

  • The association of hereditary neuropathies and heritable skeletal disorders.

    abstract::We describe two patients with associations of hereditary neuropathies and heritable skeletal disorders not previously reported. The first patient had Marfan's syndrome and hereditary motor and sensory neuropathy Type 1. The second patient had Ehlers-Danlos syndrome, Klippel-Feil syndrome and tomaculous neuropathy. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.71.834.245

    authors: Chattopadhyay AK,Kandler RH,Sharrack B

    更新日期:1995-04-01 00:00:00

  • Interstitial nephritis.

    abstract::Interstitial nephritis is an inflammatory process within the renal interstitium, and was one of the first observations made in the description of renal histopathology. Many different conditions are associated with an interstitial nephritis, and as a clinical diagnosis the term has little use unless causation is define...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.73.857.151

    authors: Dhillon S,Higgins RM

    更新日期:1997-03-01 00:00:00

  • Audit of the prevalence and investigation of iron deficiency anaemia in patients with heart failure in hospital practice.

    abstract:PURPOSE OF THE STUDY:Iron deficiency anaemia (IDA) is associated with increased morbidity and mortality in heart failure patients. The aim of our audit was to evaluate the current practice in diagnosis and assessment of IDA in patients admitted with heart failure. STUDY DESIGN:We conducted a retrospective audit of pat...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2019-136867

    authors: Simon S,Ioannou A,Deoraj S,Metaxa S,Mandal AKJ,Missouris CG

    更新日期:2020-04-01 00:00:00

  • Colonoscopy in patients aged 80 years or older and its contribution to the evaluation of rectal bleeding.

    abstract::Colonoscopies performed in patients aged 80 years or older at the Sheba Medical Center were analysed according to the primary indication for the procedure: 101 colonoscopies were performed because of rectal bleeding of at least 2 months duration, and 335 for all other indications. Carcinoma of the large bowel was foun...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.68.799.355

    authors: Bat L,Pines A,Shemesh E,Levo Y,Zeeli D,Scapa E,Rosenblum Y

    更新日期:1992-05-01 00:00:00

  • Liver disease in pregnancy.

    abstract::Pregnancy is a time of great maternal physiological and metabolic changes. This affects the biochemical and haematological parameters used in the assessment of liver disease, and it is important to appreciate the different reference ranges in pregnancy to facilitate recognition of liver disorders in pregnancy. Due to ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2009.089631

    authors: Mackillop L,Williamson C

    更新日期:2010-03-01 00:00:00

  • Urticaria--current concepts.

    abstract::The mechanisms, clinical features and management of the various forms of urticaria are discussed. The importance of histamine receptors, complement and the kinin cascade are reviewed. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.53.626.732

    authors: Taaffe A

    更新日期:1977-12-01 00:00:00

  • Pyogenic liver abscess with two normal ultrasound scans.

    abstract::I report a case of a large liver abscess causing a severe debilitating condition in which the diagnosis was delayed by several weeks following two normal ultrasound scans at days 5 and 19 of the illness. Up to one in four cases of liver abscess can be missed on ultrasound. A high degree of clinical suspicion must be m...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.64.751.373

    authors: Bunney RG

    更新日期:1988-05-01 00:00:00

  • Imaging and management of greater trochanteric pain syndrome.

    abstract::Greater trochanteric pain syndrome (GTPS) is a commonly diagnosed regional pain syndrome with a wide spectrum of aetiologies, reflecting the anatomy of the structures outside the hip joint capsule. There are five muscle tendons that insert on to the greater trochanter and three bursae in the region of the greater troc...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/postgradmedj-2013-131828

    authors: Chowdhury R,Naaseri S,Lee J,Rajeswaran G

    更新日期:2014-10-01 00:00:00

  • Continuous electrocardiographic recording (Holter method) during indapamide treatment: a study of 40 cases.

    abstract::In 40 hypertensive patients continuous ECG recording was done before and after 30 days treatment with indapamide 2.5 mg. There was no change in heart rate. In addition, the incidence of extrasystoles was not changed in patients in whom the ECG was normal before treatment (30 cases) or in 8 of the 10 patients who had a...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:

    authors: Haiat R,Lellouch A,Lanfranchi J,Witchitz S

    更新日期:1981-01-01 00:00:00

  • COVID-19 in patients with heart failure: the new and the old epidemic.

    abstract::Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread in nearly 200 countries in less than 4 months since its first identification; accordingly, the coronavirus disease 2019 (COVID 2019) has affirmed itself as a clinical challenge. The prevalence of pre-existing cardiovascular diseases in patients wi...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/postgradmedj-2020-138080

    authors: Sisti N,Valente S,Mandoli GE,Santoro C,Sciaccaluga C,Franchi F,Cameli P,Mondillo S,Cameli M

    更新日期:2020-07-30 00:00:00

  • Leuco-erythroblastosis following withdrawal from glucocorticoid therapy.

    abstract::Leuco-erythroblastosis has many known associations (Burkett, Cox and Fields, 1965; Weick, Hagedorn and Linman, 1974; Retief, 1964), but the only ones related to drug therapy are the well established response to haematinics (Burkett et al., 1965) and one possible case following anti-epileptic therapy (Retief, 1964). Th...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.53.621.391

    authors: Trenchard PM,Wells CE,Jarriwalla AG

    更新日期:1977-07-01 00:00:00

  • Gastric outlet obstruction due to gall stones (Bouveret syndrome).

    abstract::Gastric outlet obstruction by gall stone is a rare complication of a common disorder. Two cases are reported here. The investigations are conducted along the same lines as for pyloric stenosis. The diagnosis can be made with a barium meal or gastroscopy. Treatment is by surgical intervention after adequate resuscitati...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.63.744.909

    authors: Ah-Chong K,Leong YP

    更新日期:1987-10-01 00:00:00

  • Association between serum amyloid A levels and cancers: a systematic review and meta-analysis.

    abstract:OBJECTIVE:Increased serum amyloid A (SAA) levels have been investigated in various human malignancies, but a consistent perspective has not been established to date. This study systematically reviewed the association between SAA levels and cancers. METHODS:Cochrane Library, PubMed and Embase were carefully searched fo...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1136/postgradmedj-2018-136004

    authors: Zhou J,Sheng J,Fan Y,Zhu X,Tao Q,He Y,Wang S

    更新日期:2018-09-01 00:00:00

  • Recurrent sub-mucosal dissection of the oesophagus in association with achalasia.

    abstract::Submucosal dissection of the oesophagus is a rare oesophageal disorder. We report a patient who had recurrent episodes of dissection and achalasia. Both recurrence and the association with achalasia are to our knowledge unique. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.732.955

    authors: Hooper TL,Gholkar J,Smith SR,Manns JJ,Moussalli H

    更新日期:1986-10-01 00:00:00