The pharmaco-invasive approach to STEMI: when should fibrinolytic-treated patients go to the "cath lab"?

abstract：:We studied two sisters who developed large non-toxic goitres in adolescence. Deiodinase deficiency was diagnosed by a rapid thyroid uptake of radioactive iodine (RAI) at 2 hours associated with a marked fall in thyroidal 131I by 24 hours. Serial RAI scans in the second patient documented evolution of the iodine-defici...

journal_title：Postgraduate medical journal

authors： Hirsch HJ,Shilo S,Spitz IM

更新日期：1986-06-01 00:00:00

abstract：:Acute bacterial meningitis is a common neurological emergency and a leading cause of death and neurological disability worldwide. Diagnosis is based on clinical and microbiological findings with neuroimaging in the form of CT reserved for those with specific adverse clinical features or when an underlying cause such a...

journal_title：Postgraduate medical journal

authors： Hughes DC,Raghavan A,Mordekar SR,Griffiths PD,Connolly DJ

更新日期：2010-08-01 00:00:00

abstract：:Heart failure is a major problem worldwide; it is the leading cause of hospitalisation and is posing a huge financial burden. Advances in healthcare have contributed to increased life expectancy, with a resultant increase in the number of patients with chronic heart failure. For many patients who are still severely sy...

journal_title：Postgraduate medical journal

authors： Patel S,Nicholson L,Cassidy CJ,Wong KY

更新日期：2016-05-01 00:00:00

abstract：:A 27 year old woman with hepato-lenticular degeneration (Wilson's disease) was found to have primary hepatocellular carcinoma (PHC) three and a half years after she was started on treatment with D-penicillamine. The tumour was resected since when she has remained well. Her liver function tests were normal throughout t...

journal_title：Postgraduate medical journal

authors： Guan R,Oon CJ,Wong PK,Foong WC,Wee A

更新日期：1985-04-01 00:00:00

abstract：:A case of hypereosinophilic syndrome is reported. Investigation failed to reveal any precipitating cause or evidence of leukaemia. Death was due to intractable cardiac failure, and post-mortem examination showed infiltration of the myocardium with sheets of immature cells. The relevance of these cells is discussed and...

journal_title：Postgraduate medical journal

authors： Scott DG,Leatherdale BA

更新日期：1979-01-01 00:00:00

abstract：:Between 1975 and 1982 in 2 centres in Glasgow, 53 previously untreated patients with aggressive non-Hodgkin's lymphomas received chemotherapy consisting of one of the following regimens-CVP, MOPP, CHOP or BACOP. Twenty nine patients (55%) entered complete remission (CR), 20 (38%) had partial remission (PR) and 4 (7%) ...

journal_title：Postgraduate medical journal

authors： Cunningham D,Hepplestone A,Gilchrist NL,Dagg JH,Evans IL,Soukop M

更新日期：1987-01-01 00:00:00

abstract：:Hypothyroidism over a lifetime is rare. Such a case is reported due to post-coupling dyshormonogenesis in a patient who had developed an aortic aneurysm. It is proposed that the aortic aneurysm could have arisen as a direct consequence of the hypothyroidism. Furthermore, Reilly bodies, which are deposits of mucopolysa...

journal_title：Postgraduate medical journal

authors： Savage C,Deanfield JE,Jung RT

更新日期：1982-11-01 00:00:00

abstract：:A 68 year old man developed cranial diabetes insipidus 3 years after the diagnosis of myelofibrosis, coincident with a marked increase in nucleated cell count. No mass lesion was demonstrable on computed tomographic or magnetic resonance imaging. It is suggested that hypothalamic damage was caused by local infiltratio...

journal_title：Postgraduate medical journal

authors： Dornan TL,Gillett G,Jones PA,Jeffcoate WJ

更新日期：1989-01-01 00:00:00

abstract：:The effect of digoxin (0.25 mg t.d.s.) given orally for 5 days, on sodium excretion, plasma renin activity, plasma aldosterone and blood pressure has been studied in 6 normotensive subjects, on a constant sodium intake. Average serum digoxin level measured in 5 subjects on the 5th day of treatment was in the upper ran...

journal_title：Postgraduate medical journal

authors： Cappuccio FP,Markandu ND,Sagnella GA,MacGregor GA

更新日期：1986-04-01 00:00:00

abstract：:A host/vector system suitable for large-scale production of HBsAg has been constructed and optimized in terms of the expression plasmid and yeast host strain in order to permit fermentation to very high cell densities. The final expression plasmid contains the coding sequence of the major HBsAg protein (P24) flanked b...

journal_title：Postgraduate medical journal

authors： Harford N,Cabezon T,Colau B,Delisse AM,Rutgers T,De Wilde M

更新日期：1987-01-01 00:00:00

abstract：:A case of severe hypercalcaemia associated with a non-secretory multiple myeloma in the absence of skeletal deposits is described. The importance of considering this condition in the differential diagnosis of hypercalcaemia in the elderly is discussed. ...

journal_title：Postgraduate medical journal

authors： Chew D,Playfer JR

更新日期：1988-06-01 00:00:00

abstract：:Serum thyrotrophin has been measured before and after the intravenous administration of 200 micrograms of thyrotrophin-releasing hormone in 91 white subjects (33 stable diabetic patients and 58 healthy controls), none of whom had any clinical evidence of thyroid or pituitary dysfunction. Seven of the diabetic subjects...

journal_title：Postgraduate medical journal

authors： Small M,Cohen HN,MacLean JA,Beastall GH,MacCuish AC

更新日期：1986-06-01 00:00:00

abstract：:Churg-Strauss syndrome is a systemic vasculitis. Its most frequent complications are heart diseases and asthma. Usually, cardiological manifestations are pericarditis, cardiac failure and myocardial infarction. Endobronchial granulomas identified by bronchoscopy are unusual. We present the case of a man with congestiv...

journal_title：Postgraduate medical journal

authors： Alvarez-Sala R,Prados C,Armada E,Del Arco A,Villamor J

更新日期：1995-06-01 00:00:00

abstract：:We describe two patients with associations of hereditary neuropathies and heritable skeletal disorders not previously reported. The first patient had Marfan's syndrome and hereditary motor and sensory neuropathy Type 1. The second patient had Ehlers-Danlos syndrome, Klippel-Feil syndrome and tomaculous neuropathy. ...

journal_title：Postgraduate medical journal

authors： Chattopadhyay AK,Kandler RH,Sharrack B

更新日期：1995-04-01 00:00:00

abstract：:Cystinuria is an autosomal recessive disorder in renal tubular and intestinal transport of dibasic amino acids, which results in increased urinary excretion of cystine, ornithine, lysine and arginine. It affects 1 in 20 000 people and is caused by a defect in the rBAT gene on chromosome 2. Development of urinary tract...

journal_title：Postgraduate medical journal

authors： Ahmed K,Dasgupta P,Khan MS

更新日期：2006-12-01 00:00:00

abstract：:The healthcare industry has seen an increase in the adoption of team training, such as crew resource management (CRM), to improve teamwork and coordination within acute care medical teams. A meta-analysis was carried out in order to quantify the effects of CRM training on reactions, learning, behaviour and clinical ca...

journal_title：Postgraduate medical journal

authors： O'Dea A,O'Connor P,Keogh I

更新日期：2014-12-01 00:00:00

abstract：:Repeated pneumonia and hypogammaglobulinaemia was associated with long term low dose steroid therapy. Clinical improvement with restoration of antibody levels followed substitution of aerosol for oral therapy. ...

journal_title：Postgraduate medical journal

authors： Lee RJ,Fay AC

更新日期：1985-06-01 00:00:00

abstract：:A case is presented of a young competitive body-builder who abused anabolic steroid drugs and developed profound symptomatic hypogonadotrophic hypogonadism. With the help of prescribed testosterone (Sustanon) he stopped taking anabolic drugs, and later stopped Sustanon also. Hypogonadism returned, but was successfully...

journal_title：Postgraduate medical journal

authors： Gill GV

更新日期：1998-01-01 00:00:00

abstract：:A 34 year old female presented with weight loss and hepatomegaly. Liver biopsy revealed clinically unsuspected metastatic choriocarcinoma. Severe haemorrhage occurred, and the patient died following complications after laparotomy. The possibility of choriocarcinoma should be remembered in women of child-bearing age wh...

journal_title：Postgraduate medical journal

authors： Alveyn CG,Loehry CA

更新日期：1988-12-01 00:00:00

abstract：:In recent years, the short Synacthen test (SS) has become the most widely used test to assess adrenal reserve. Despite its frequent use, there are still several areas related to the short Synacthen test (SST), which have no consensus including the optimum sampling times, that is, whether a 60 min post-Synacthen admini...

journal_title：Postgraduate medical journal

authors： Dineen R,Mohamed A,Gunness A,Rakovac A,Cullen E,Barnwell N,Neary C,Behan LA,Boran G,Gibney J,Sherlock M

更新日期：2020-02-01 00:00:00

abstract：:The abnormalities of erythrocytes, leucocytes, thrombocytes and coagulation that have been reported, particularly in more recent years, to be associated with hyperthyroidism are surveyed. Several areas are highlighted where further investigations could lead to clinically useful insights, improved information about the...

journal_title：Postgraduate medical journal

authors： Ford HC,Carter JM

更新日期：1988-10-01 00:00:00

abstract：:Forty-five healthy men aged 21-34 years took part in a double-blind, parallel-group, placebo-controlled study of the effects of 28 days' treatment with lornoxicam 4 mg twice daily or indomethacin 50 mg twice daily on faecal blood loss and the endoscopic appearances of gastric and duodenal mucosa. After an initial endo...

journal_title：Postgraduate medical journal

authors： Warrington SJ,Debbas NM,Farthing M,Horton M,Johnston A,Thillainayagam A,Turner P,Ferber H

更新日期：1990-08-01 00:00:00

abstract：:We present a 78-year-old woman with clinical acute hypopituitarism in whom pathologic findings showed lymphocytic hypophysitis and retroperitoneal fibrosis. Lymphocytic hypophysitis should be included in the differential diagnosis of hypopituitarism at any age. The association with idiopathic retroperitoneal fibrosis ...

journal_title：Postgraduate medical journal

authors： Alvarez A,Cordido F,Sacristán F

更新日期：1997-11-01 00:00:00

abstract：:Priapism is a pathological condition of penile erection that persists beyond, or is unrelated to, sexual stimulation. Pathologically and clinically, two subtypes are seen-the high flow (non-ischaemic) variety and the low flow (ischaemic) priapism. The low flow type is more dangerous, as these patients are susceptible ...

journal_title：Postgraduate medical journal

authors： Cherian J,Rao AR,Thwaini A,Kapasi F,Shergill IS,Samman R

更新日期：2006-02-01 00:00:00

abstract：:A case of hyperemesis gravidarum at 9 weeks' gestation is described for which no cause could initially be found. Intravenous feeding was needed as a life preserving measure and following improvement on this regime the patient went into a thyrotoxic crisis which was successfully diagnosed and treated. The continuing pr...

journal_title：Postgraduate medical journal

authors： Valentine BH,Jones C,Tyack AJ

更新日期：1980-10-01 00:00:00

abstract：:A case of acute necrotizing pancreatitis in a 53-year-old man with an ectopic adrenocorticotrophin (ACTH) producing bronchial carcinoma is described. The aetiology of acute pancreatitis in relation to steroid therapy and malignancy is discussed and it is suggested that excess endogenous steroid production may also cau...

journal_title：Postgraduate medical journal

authors： Clague HW,Warren B,Krasner N

更新日期：1984-09-01 00:00:00

abstract：:We report the case of a 58 year old man in whom an unusually prolonged infection with Toxoplasma gondii was the presenting feature of an underlying non-Hodgkin's lymphoma. This case demonstrates the particular usefulness of the IgM ELISA test in monitoring disease activity. ...

journal_title：Postgraduate medical journal

authors： Dudley NJ,Balfour AH

更新日期：1988-11-01 00:00:00

abstract：:Amlodipine is a dihydropyridine calcium antagonist with a unique pharmacokinetic profile providing advantages over other therapies of its kind. It has been shown to possess high oral absorption, long elimination half-life, smooth onset of action and long duration of pharmacodynamic activity. These properties result in...

journal_title：Postgraduate medical journal

authors： Taylor SH

更新日期：1991-01-01 00:00:00

abstract：:A pre-term infant being ventilated for respiratory distress syndrome developed severe localized pulmonary interstitial emphysema which was successfully treated by selective bronchial intubation. ...

journal_title：Postgraduate medical journal

authors： Oliver JE,Smith IJ

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To examine the current attitudes towards the prevention of venous thromboembolism among a cohort of surgeons. DESIGN:A postal survey, comprising a questionnaire covering various aspects of venous thromboembolism prophylaxis was sent to all (n=84) consultant general surgeons in Wales. RESULTS:Replies were re...

journal_title：Postgraduate medical journal

authors： Williams EV,Williams RS,Hughes JL,Williams KL,Foster ME,Lewis MH

更新日期：2002-02-01 00:00:00