Evolution of hypothyroidism in familial goitre due to deiodinase deficiency: report of a family and review of the literature.

abstract：:Gastric outlet obstruction by gall stone is a rare complication of a common disorder. Two cases are reported here. The investigations are conducted along the same lines as for pyloric stenosis. The diagnosis can be made with a barium meal or gastroscopy. Treatment is by surgical intervention after adequate resuscitati...

journal_title：Postgraduate medical journal

authors： Ah-Chong K,Leong YP

更新日期：1987-10-01 00:00:00

abstract：:The effect of captopril monotherapy on blood pressure and metabolism was investigated in a placebo-controlled study in 30 non-insulin dependent (Type II) diabetic subjects during a 3-week observation period (run-in/drug; placebo/wash-out) on a metabolic ward. Captopril significantly reduced both systolic and diastolic...

journal_title：Postgraduate medical journal

authors： Rett K,Wicklmayr M,Tschollar W,Dietze G,Mehnert H

更新日期：1988-01-01 00:00:00

abstract：:Posterior leukoencephalopathy syndrome is a newly recognised brain disorder that predominantly affects the cerebral white matter. Oedematous lesions particularly involve the posterior parietal and occipital lobes, and may spread to basal ganglia, brain stem, and cerebellum. This rapidly evolving neurological condition...

journal_title：Postgraduate medical journal

authors： Garg RK

更新日期：2001-01-01 00:00:00

abstract：:The effective management of constipation in childhood requires an understanding of the ways that the physical and psychological factors interact. The early difficulty with defecation that leads to pain, fear, and refusal to use the pot or lavatory often progresses to the formation of vicious cycles of increasing faeca...

journal_title：Postgraduate medical journal

authors： Clayden G,Keshtgar AS

更新日期：2003-11-01 00:00:00

abstract：:Oral administration of 1 g of acetazolamide to 8 normal subjects studied at sea level and in normoxia caused an acute increase in cerebral blood flow (CBF). During the subsequent prolonged oral treatment with 1 g of acetazolamide daily, CBF returned to normal within 2 days. The alveolar CO2 tension decreased gradually...

journal_title：Postgraduate medical journal

authors： Lassen NA,Friberg L,Kastrup J,Rizzi D,Jensen JJ

更新日期：1987-03-01 00:00:00

abstract：:Acute retinal necrosis (ARN), also known as Kirisawa-type uveitis, is an uncommon condition caused by infection of the retina by one of the herpes family of viruses, most typically varicella zoster virus or herpes simplex virus and less commonly cytomegalovirus. Clinical diagnosis can be challenging and is often aided...

journal_title：Postgraduate medical journal

authors： Wong RW,Jumper JM,McDonald HR,Johnson RN,Fu A,Lujan BJ,Cunningham ET Jr

更新日期：2013-08-01 00:00:00

abstract：:We report four cases of Bartter's syndrome in two consecutive generations of an Irish family. Diagnoses were made on the basis of characteristic clinical features, blood and urine biochemistry with additional evidence from renal biopsy in one case. The aetiology, treatment and inheritance of the syndrome are discussed...

journal_title：Postgraduate medical journal

authors： Crowe P,Ahmad A,O'Byrne K,Cullen MJ

更新日期：1993-10-01 00:00:00

abstract：:The empty sella syndrome (ESS) presents a varied clinical and radiographic picture. It may remain asymptomatic or may stimulate an intrasellar growth thereby causing diagnostic and therapeutic problems. An air encephalogram (AEG) is required for diagnosis. The purpose of this paper is to review the clinical and radiol...

journal_title：Postgraduate medical journal

authors： Sachdev Y,Evered DC,Appleby A,Hall R

更新日期：1976-11-01 00:00:00

abstract：:A previously healthy 17 year old boy had Staphylococcus aureus endocarditis presenting as acute scrotal pain. There was no trauma or evidence of scrotal or epididymal infection. The pain subsided after therapy for endocarditis was started. ...

journal_title：Postgraduate medical journal

authors： Watanakunakorn C

更新日期：1987-07-01 00:00:00

abstract：:Four cases of ileo-caecal tuberculosis in Asian immigrants were seen in a 6-month period at The London Hospital. Although rare in Caucasians, this condition is an important cause of gastrointestinal symptoms in this ethnic group. Definitive diagnosis can frequently be made only by histological examination and culture ...

journal_title：Postgraduate medical journal

authors： Croker J,Record CO,Wright JT

更新日期：1978-06-01 00:00:00

abstract：:Repeated pneumonia and hypogammaglobulinaemia was associated with long term low dose steroid therapy. Clinical improvement with restoration of antibody levels followed substitution of aerosol for oral therapy. ...

journal_title：Postgraduate medical journal

authors： Lee RJ,Fay AC

更新日期：1985-06-01 00:00:00

abstract：:The mechanisms of the antinociceptive action of flupirtine, a novel non-opioid analgesic, were investigated in animals. It was found that this effect could be abolished by pre-treatment with reserpine. Furthermore, it could be dose-dependently antagonized by yohimbine and changes in the EEG of the rat observed after a...

journal_title：Postgraduate medical journal

authors： Szelenyi I,Nickel B

更新日期：1987-01-01 00:00:00

abstract：:The insulin resistance/metabolic syndrome is characterised by the variable coexistence of hyperinsulinaemia, obesity, dyslipidaemia, and hypertension. The pathogenesis of the syndrome has multiple origins, but obesity and sedentary lifestyle coupled with diet and still largely unknown genetic factors clearly interact ...

journal_title：Postgraduate medical journal

authors： Kolovou GD,Anagnostopoulou KK,Cokkinos DV

更新日期：2005-06-01 00:00:00

abstract：:By comparison with other calcium antagonist drugs, amlodipine has unique pharmacokinetic properties that are probably attributable to its chemical structure and positive ionic charge at physiological pH. Thus, amlodipine undergoes gradual absorption from the gastro-intestinal tract and is widely distributed throughout...

journal_title：Postgraduate medical journal

authors： Elliott HL,Meredith PA

更新日期：1991-01-01 00:00:00

abstract：PURPOSE OF THE STUDY:There are approximately 35 000 in-hospital cardiac arrests in the UK each year. Successful resuscitation requires integration of the medical science, training and education of clinicians and implementation of best practice in the clinical setting. In 2015, the International Liaison Committee on Res...

journal_title：Postgraduate medical journal

authors： Carberry J,Couper K,Yeung J

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:To determine whether exocrine pancreatic function is impaired in patients with coeliac disease (CD) in our population and to evaluate its clinical importance. METHODS:Pancreatic exocrine function was determined by measuring faecal elastase-1 (FE) concentration. CD was diagnosed by serological testing using ...

journal_title：Postgraduate medical journal

authors： Vujasinovic M,Tepes B,Volfand J,Rudolf S

更新日期：2015-09-01 00:00:00

abstract：:Six Arabs subjects (three postpubertal, two prepubertal and one pubertal) from three interrelated Omani families with male pseudohermaphroditism due to 5 alpha-reductase-2 deficiency were evaluated. These subjects had been raised as girls since birth as they were born with a clitoral-like phallus and ambiguous externa...

journal_title：Postgraduate medical journal

authors： al-Attia HM

更新日期：1997-12-01 00:00:00

abstract：:Cystinuria is an autosomal recessive disorder in renal tubular and intestinal transport of dibasic amino acids, which results in increased urinary excretion of cystine, ornithine, lysine and arginine. It affects 1 in 20 000 people and is caused by a defect in the rBAT gene on chromosome 2. Development of urinary tract...

journal_title：Postgraduate medical journal

authors： Ahmed K,Dasgupta P,Khan MS

更新日期：2006-12-01 00:00:00

abstract：:We report the case of a 66 year old woman with clinical manifestations of giant-cell arteritis, positive temporal artery biopsy and excellent response to prednisone, who developed massive cerebral infarcts after 5 days of treatment. Computed tomographic and magnetic resonance imaging scans revealed multiple infarcts i...

journal_title：Postgraduate medical journal

authors： Collazos J,García-Moncó C,Martín A,Rodriguez J,Gómez MA

更新日期：1994-03-01 00:00:00

abstract：:Although primary percutaneous coronary intervention (PCI) in clinical trials has lower rates of reinfarction, stroke and mortality than fibrinolytic therapy, because of system delays in routine practice, field triage and prehospital administration of fibrinolytic therapy may lead to similar clinical outcomes, especial...

journal_title：Postgraduate medical journal

authors： Edmond JJ,Juergens CP,French JK

更新日期：2009-06-01 00:00:00

abstract：:With the introduction of the New Deal and the Calman Report, the duration of higher specialist training will be halved. We have examined the effect of reduced on-call rotas on exposure to relatively uncommon out-of-hours emergencies in cardiothoracic surgery. Operations for post-infarction ventricular septal defect, a...

journal_title：Postgraduate medical journal

authors： Kelty C,Duffy J,Cooper G

更新日期：1999-06-01 00:00:00

abstract：PURPOSE:Workplace-based assessments (WBAs) were originally intended to inform learning and development by structuring effective observation-based feedback. The success of this innovation has not yet been established due in part to the widely varied tools, implementation strategies and research approaches. Using a conce...

journal_title：Postgraduate medical journal

authors： Barrett A,Galvin R,Scherpbier AJ,Teunissen PW,O'Shaughnessy A,Horgan M

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Benefits of exposure to global health training during medical education are well documented and residents' demand for this training is increasing. Despite this, it is offered by few US obstetrics and gynaecology (OBGYN) residency training programmes. OBJECTIVES:To evaluate interest, perceived importance, pr...

journal_title：Postgraduate medical journal

authors： Nathan LM,Banks EH,Conroy EM,McGinn AP,Ghartey JP,Wagner SA,Merkatz IR

更新日期：2015-12-01 00:00:00

abstract：:Antenatal appendicular perforation leading to localized meconium peritonitis and intestinal obstruction is reported in a premature neonate. The baby was successfully treated by a limited ileocaecal resection. ...

journal_title：Postgraduate medical journal

authors： Narasimharao KL,Mitra SK,Pathak IC

更新日期：1987-11-01 00:00:00

abstract：:This review presents our experience in the use of propranolol in the management of cardiac infarction. The drug has now been shown to have a definite place, not only in the prevention of cardiac infarction, but also in the treatment of some of the complications. The drug has also been advocated because it may minimiz...

journal_title：Postgraduate medical journal

authors： Sloman G,Hunt D,Ross D

更新日期：1976-01-01 00:00:00

abstract：:In 91 patients with bronchiectasis seen over 6 years, a positive mycobacterial culture was obtained in 12 cases (13%). The organisms isolated were Mycobacterium tuberculosis in nine cases, Mycobacterium avium in two cases and Mycobacterium tuberculosis and chelonei were obtained on separate occasions in one case. Comp...

journal_title：Postgraduate medical journal

authors： Chan CH,Ho AK,Chan RC,Cheung H,Cheng AF

更新日期：1992-11-01 00:00:00

abstract：AIMS:To review the clinical and pathological factors associated with fulminant amoebic colitis (FAC) requiring colonic resection and its outcome. METHODS:We retrospectively identified adult patients admitted to our centre between June 2007 and December 2011 with FAC who underwent colonic resection and were diagnosed w...

journal_title：Postgraduate medical journal

authors： Chaturvedi R,Gupte PA,Joshi AS

更新日期：2015-04-01 00:00:00

abstract：:A 32 year old man with alcohol-induced pain over a right submandibular swelling is described. Excision biopsy of this swelling revealed chronic sialadenitis and the symptoms promptly ceased following this excision. We speculate on the possible pathophysiological mechanism. ...

journal_title：Postgraduate medical journal

authors： Okany CC,Akinsete I,Akinyanju OO

更新日期：1990-11-01 00:00:00

abstract：:Localized fibrous mesothelioma of the pleura is an uncommon neoplasm. Very rarely (there have been three previous cases) it may occur as an isolated mediastinal tumour. Such a tumour was present for at least 3 years in a 47 year old man, causing shortness of breath and superior vena cava syndrome. A mass weighing over...

journal_title：Postgraduate medical journal

authors： Balassiano M,Reichert N,Rosenman Y,Hertcheg E,Lieberman Y,Yellin A

更新日期：1989-10-01 00:00:00

abstract：:The causes of death, as determined by autopsy, in 10 patients dying from the acute effects of phaeochromocytoma were myocardial infarction (five patients), left ventricular failure (two patients), cerebral haemorrhage (two patients) and circulatory collapse with malignant phaeochromocytoma (one patient). Most patients...

journal_title：Postgraduate medical journal

authors： Cohen CD,Dent DM

更新日期：1984-02-01 00:00:00