Multiple strokes after initiation of steroid therapy in giant cell arteritis.

Abstract:

:We report the case of a 66 year old woman with clinical manifestations of giant-cell arteritis, positive temporal artery biopsy and excellent response to prednisone, who developed massive cerebral infarcts after 5 days of treatment. Computed tomographic and magnetic resonance imaging scans revealed multiple infarcts in areas irrigated by both the carotid and vertebrobasilar systems bilaterally. A four-vessel angiography performed 19 days later revealed only mild atheromatous disease. Anticardiolipin antibodies were negative and a transoesophageal echocardiogram was normal. Stroke during the first 2 weeks of therapy in giant-cell arteritis, especially in the vertebrobasilar territory, has been previously reported. Anticoagulation during the first weeks of steroid treatment in these patients might be advisable.

journal_name

Postgrad Med J

authors

Collazos J,García-Moncó C,Martín A,Rodriguez J,Gómez MA

doi

10.1136/pgmj.70.821.228

subject

Has Abstract

pub_date

1994-03-01 00:00:00

pages

228-30

issue

821

eissn

0032-5473

issn

1469-0756

journal_volume

70

pub_type

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