Bartter's syndrome in two generations of an Irish family.

abstract：PURPOSE OF THE STUDY:Resistin, a recently discovered proinflammatory cytokine, has been strongly linked to kidney dysfunction. The aim of this study was to determine the relationship of serum resistin with serum cystatin C (sCysC) and albuminuria, two sensitive endogenous markers of renal function, in elderly male pati...

journal_title：Postgraduate medical journal

authors： Zhang M,Cui H,Zhu BP,Fu SH

更新日期：2015-03-01 00:00:00

abstract：:Motor neurone disease (MND), or amyotrophic lateral sclerosis (ALS), is a neurodegenerative disorder of unknown aetiology. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Confirming the diagnosis may initially be difficult until the full clinical features ar...

journal_title：Postgraduate medical journal

authors： Talbot K

更新日期：2002-09-01 00:00:00

abstract：:This purports to be the first recorded case of carcinoma of the pancreas presenting as a mechanical obstruction of the colon. The literature relating to some other rare modes of presentation is reviewed, and a comment made on the desirability of routine post-mortem studies. ...

journal_title：Postgraduate medical journal

authors： Tresadern JC

更新日期：1981-01-01 00:00:00

abstract：:The addition of amino acid supplements to peritoneal dialysis fluid has been studied in 8 patients with compromised renal function requiring peritoneal dialysis. By the addition of 10 ml of Vamin-glucose solution to each one litre of peritoneal dialysate, amino acid losses were curtailed, no significant alterations oc...

journal_title：Postgraduate medical journal

authors： Jackson MA,Talbot S,Thomas DW,Lee HA

更新日期：1979-09-01 00:00:00

abstract：:Functional metastatic adrenocortical carcinoma is an uncommon cause of Cushing's syndrome, which rarely responds to conventional treatment. A patient presenting with Cushing's syndrome secondary to adrenocortical carcinoma underwent surgical resection. Postoperatively, she developed metastatic disease resistant to con...

journal_title：Postgraduate medical journal

authors： Chan NN,Isaacs AJ

更新日期：1999-02-01 00:00:00

abstract：INTRODUCTION:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been caused the greatest pandemic of our century. Many of the deaths related to it are due to a systemic inflammatory response, which has been called 'cytokine storm'. OBJECTIVES:We developed a comprehensive review of the pathophysiology mec...

journal_title：Postgraduate medical journal

authors： Mélo Silva Júnior ML,Souza LMA,Dutra REMC,Valente RGM,Melo TS

更新日期：2020-10-02 00:00:00

abstract：:Juvenile myoclonic epilepsy (JME) is a hereditary, idiopathic, generalised epilepsy and is found in 5%-11% of patients with epilepsy. It is characterised by myoclonic jerks, occasional generalised tonic-clonic seizures, and sometimes absence seizures. JME continues to be under-appreciated and under-diagnosed. Accurate...

journal_title：Postgraduate medical journal

authors： Renganathan R,Delanty N

更新日期：2003-02-01 00:00:00

abstract：:The elderly, the very young, and the sick are known to be adversely affected by high environmental temperatures. In a retrospective open case-note review of 872 patients in a large institution during a hot summer we identified characteristics in the elderly that increase the risk of marginal hyperthermia. Women were m...

journal_title：Postgraduate medical journal

authors： Vassallo M,Gera KN,Allen S

更新日期：1995-04-01 00:00:00

abstract：:Sudden cardiac death is the leading cause of mortality among young athletes with an incidence of 1-2 per 100,000 athletes per annum. It is described as 'an event that is non-traumatic, non-violent, unexpected, and resulting from sudden cardiac arrest within six hours of previously witnessed normal health'. Most predis...

journal_title：Postgraduate medical journal

authors： Pugh A,Bourke JP,Kunadian V

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:We aimed to report the incidence of hospital-acquired hypophosphataemia and hyperphosphataemia along with their associated in-hospital mortality. METHODS:We included 15 869 adult patients hospitalised at a tertiary medical referral centre from January 2009 to December 2013, who had normal serum phosphate le...

journal_title：Postgraduate medical journal

authors： Thongprayoon C,Cheungpasitporn W,Chewcharat A,Petnak T,Mao MA,Srivali N,Bathini T,Vallabhajosyula S,Qureshi F,Kashani K

更新日期：2020-10-21 00:00:00

abstract：:Splenic peliosis was identified at necropsy in a 62-year-old woman receiving continuous ambulatory peritoneal dialysis for end-stage renal failure, and erythropoietin therapy for uraemia and anaemia. The immediate cause of death was arrhythmia related to ischaemic heart disease, following an episode of intramuscular h...

journal_title：Postgraduate medical journal

authors： Lam KY,Chan AC,Chan TM

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The diagnosis of spinal tuberculosis (ST) is difficult and it commonly presents at an advanced stage. The management and follow up is complicated by a lack of guidance on the appropriate use and interpretation of spinal magnetic resonance studies (MR). AIMS:A retrospective study was performed at a UK centre...

journal_title：Postgraduate medical journal

authors： Cormican L,Hammal R,Messenger J,Milburn HJ

更新日期：2006-01-01 00:00:00

abstract：:Although recognized since the 1930s, slow infections have only recently received considerable attention. There are three types, group A (related to the type C RNA viruses), group B (bizarre agents such as scrapie and kuru) and group C (viruses such as measles which normally produce acute infections but which are behav...

journal_title：Postgraduate medical journal

authors： Sutton RN

更新日期：1979-02-01 00:00:00

abstract：:Although the relationship between group A streptococcal upper respiratory tract infection and the development of acute rheumatic fever has been known for many years, the pathogenetic mechanism(s) have never been defined. Thus, the mechanism of damage to the valves and to the myocardium in patients with rheumatic fever...

journal_title：Postgraduate medical journal

authors： Kaplan EL

更新日期：1992-01-01 00:00:00

abstract：:Localized fibrous mesothelioma of the pleura is an uncommon neoplasm. Very rarely (there have been three previous cases) it may occur as an isolated mediastinal tumour. Such a tumour was present for at least 3 years in a 47 year old man, causing shortness of breath and superior vena cava syndrome. A mass weighing over...

journal_title：Postgraduate medical journal

authors： Balassiano M,Reichert N,Rosenman Y,Hertcheg E,Lieberman Y,Yellin A

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of acanthosis nigricans (AN) in type 2 diabetes mellitus (T2DM) and its correlation with various anthropometric measurements in Indians. METHODS:One hundred and fifty consecutive subjects with T2DM attending the diabetes clinic at a tertiary referral centre in North India were con...

journal_title：Postgraduate medical journal

authors： Grandhe NP,Bhansali A,Dogra S,Kumar B

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:After primary percutaneous coronary intervention (PPCI) in patients with acute ST elevation myocardial infarction (STEMI), dual antiplatelet therapy (DAPT) is recommended to continue for 1 year. Occasionally, DAPT interruption may be required due to bleeding issues or unplanned surgical procedures. OBJECTIV...

journal_title：Postgraduate medical journal

authors： Tam CC,Lee J,Chan KW,Lam CC,Wong YT,Chan E,Sze M,Lam YM,Chan C,Tse HF,Siu CW

更新日期：2020-01-01 00:00:00

abstract：:Ganglioneuroblastoma in the spinal region is rare, the treatment of choice being surgical excision. We present a 21 year old male who was diagnosed to have this condition in the dorsolumbar spinal region. The tumour was extending intraspinally and was unresectable. Combination chemotherapy with Adriamycin (doxorubicin...

journal_title：Postgraduate medical journal

authors： Raina V,Kamble R,Tanwar R,Singh SP,Sharma S

更新日期：1993-09-01 00:00:00

abstract：:Fifteen patients who had undergone a 14 inches X 4 inches jejuno-ileal bypass operation for obesity, 3 to 4 years earlier, were investigated by iliac bone biopsy, radiology and routine biochemistry, including 25-hydroxy-vitamin D and parathyroid hormone estimations. Two patients had histological osteomalacia which was...

journal_title：Postgraduate medical journal

authors： Gilmore IT,Eastwood JB,Ellis WR,Luck VA,Fenton S,O'Grady AJ,Harris E,Murray-Lyon IM

更新日期：1983-05-01 00:00:00

abstract：:Studies on hypouricaemia observed in a patient with 48,XXYY syndrome revealed an abnormality in renal urate handling. His renal urate clearance was abnormally increased. Inosine administration and provocative tests using probenecid and pyrazinamide identified an isolated renal tubular abnormality with increased urate ...

journal_title：Postgraduate medical journal

authors： Nakajima H,Tajima K,Nakajima T,Iida S,Sumi S,Kono N,Moriwaki K,Nonaka K,Tarui S

更新日期：1986-03-01 00:00:00

abstract：:A case of hyperemesis gravidarum at 9 weeks' gestation is described for which no cause could initially be found. Intravenous feeding was needed as a life preserving measure and following improvement on this regime the patient went into a thyrotoxic crisis which was successfully diagnosed and treated. The continuing pr...

journal_title：Postgraduate medical journal

authors： Valentine BH,Jones C,Tyack AJ

更新日期：1980-10-01 00:00:00

abstract：AIM:To obtain the views of specialist registrars on specialty care in the community. METHOD:Specialist registrars from five Deaneries in England completed an online questionnaire about their views on employment prospects, the role of specialty care in the community, and the need for additional training in this area. ...

journal_title：Postgraduate medical journal

authors： Azam N,Moshkovska T,Mayberry JF

更新日期：2007-01-01 00:00:00

abstract：:Five cases of strangulated femoral hernia, all with a delay in establishing the diagnosis, are reported here. These cases illustrate the continuing difficulties experienced, both in primary care and hospital practice, in making this diagnosis despite the clinical awareness of this condition. ...

journal_title：Postgraduate medical journal

authors： Heys SD,Brittenden J

更新日期：1991-01-01 00:00:00

abstract：:This paper reviews the development of cerebral scintigraphy from its early days of planar imaging with simple technetium-99m labelled compounds to the recent revival of the technique in the form of positron-emission and single-photon emission tomography. A short explanation of instrumentation and radiopharmaceuticals ...

journal_title：Postgraduate medical journal

authors： Shepstone BJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:There is paucity of evidence regarding the role of drain in laparoscopic cholecystectomy (LC) in acute calculous cholecystitis (ACC), and surgeons have placed the drains based on their experiences, not on evidence-based guidelines. This study aims to assess the value of drain in LC for ACC in a randomised co...

journal_title：Postgraduate medical journal

authors： Valappil MV,Gulati S,Chhabra M,Mandal A,Bakshi S,Bhattacharyya A,Ghatak S

更新日期：2020-10-01 00:00:00

abstract：:There is an increasing awareness on the part both of the media and the profession of the need to co-operate in providing information and education on medical matters. This co-operation should be strongly encouraged. Where children are concerned the opportunities for education are great. ...

journal_title：Postgraduate medical journal

authors： Jolly H

更新日期：1978-03-01 00:00:00

abstract：:Some antifungal agents have been tested qualitatively in various associations against species of Candida, Cryptococcus and Torulopsis. The method used was the channel test and the results are confirmed by comparison with the serial dilution test in agar. The antagonism in vitro with the combination of amphotericin B i...

journal_title：Postgraduate medical journal

authors： Dupont B,Drouhet E

更新日期：1979-09-01 00:00:00

abstract：:It has long been accepted that communication is of central importance in healthcare, and a core aspect of clinical competence. Many educational institutions and Royal Colleges now reflect this and consider communication skills a priority in postgraduate examination. The new examination "Practical Assessment of Clinica...

journal_title：Postgraduate medical journal

authors： Dacre J,Richardson J,Noble L,Stephens K,Parker N

更新日期：2004-12-01 00:00:00

abstract：:Coagulation problems in pregnancy are primarily associated with overactivity of the intrinsic clotting system. This accounts for the increased incidence of thrombo-embolism during pregnancy. Where specific obstetric complications cause clotting problems the common underlying feature is usually placental pathology as i...

journal_title：Postgraduate medical journal

authors： Redman CW

更新日期：1979-05-01 00:00:00

abstract：:By comparison with other calcium antagonist drugs, amlodipine has unique pharmacokinetic properties that are probably attributable to its chemical structure and positive ionic charge at physiological pH. Thus, amlodipine undergoes gradual absorption from the gastro-intestinal tract and is widely distributed throughout...

journal_title：Postgraduate medical journal

authors： Elliott HL,Meredith PA

更新日期：1991-01-01 00:00:00