Male pseudohermaphroditism due to 5 alpha-reductase-2 deficiency in an Arab kindred.

abstract：:A patient with disseminated ovarian carcinoma presented with symptoms of hypocalcaemia secondary to hypomagnesaemia. The low serum magnesium (0.4 mmol/l) appeared to be due to renal leakage with no evidence of ureteric obstruction or hydronephrosis on intravenous urogram. Parathyroid hormone activity (serum levels and...

journal_title：Postgraduate medical journal

authors： Leese GP,Jung RT,Browning MC

更新日期：1993-07-01 00:00:00

abstract：:The mechanisms of the antinociceptive action of flupirtine, a novel non-opioid analgesic, were investigated in animals. It was found that this effect could be abolished by pre-treatment with reserpine. Furthermore, it could be dose-dependently antagonized by yohimbine and changes in the EEG of the rat observed after a...

journal_title：Postgraduate medical journal

authors： Szelenyi I,Nickel B

更新日期：1987-01-01 00:00:00

abstract：:Aspirin was first synthesised 100 years ago and its preparation and marketing is generally reckoned to have been the foundation of the pharmaceutical industry. For most of the time since then it has been used for the relief of pain and fever. The modern phase of aspirin use commenced with the reporting in 1974 of a ra...

journal_title：Postgraduate medical journal

authors： Elwood PC,Hughes C,O'Brien JR

更新日期：1998-10-01 00:00:00

abstract：:The frequency and characteristics of chest pain and non-respiratory symptoms were investigated in patients admitted with acute asthma. One hundred patients with a mean admission peak flow rate of 38% normal or predicted were interviewed using a questionnaire. Chest pain occurred in 76% and was characteristically a dul...

journal_title：Postgraduate medical journal

authors： Edmondstone WM

更新日期：2000-07-01 00:00:00

abstract：:Perforation of the gastrointestinal tract by ingested foreign bodies is rare; the diagnosis of pyogenic liver abscess resulting from such perforations is usually made at post-mortem. We present a case of perforation of the gut, due to an ingested dental plate, with a resultant pyogenic liver abscess, which presented a...

journal_title：Postgraduate medical journal

authors： Shaw PJ,Freeman JG

更新日期：1983-07-01 00:00:00

abstract：:Both acute myocardial infarction and reperfusion therapy with thrombolytic agents may be associated with bradyarrhythmias, and there may be a case for 'prophylactic' insertion of a temporary pacing wire in selected patients. We describe 4 patients in whom clinical decisions had to be made concerning the appropriatenes...

journal_title：Postgraduate medical journal

authors： Lim CW,Bennie MJ,Lim R

更新日期：1991-07-01 00:00:00

abstract：:Liver transplantation is the accepted treatment for a wide variety of liver diseases in children. Over the past 10 years a number of innovative surgical techniques have been developed to overcome the shortage of size matched donors particularly in children less than 5 years of age. Graft and patient survival at one ye...

journal_title：Postgraduate medical journal

authors： Vilca-Melendez H,Heaton ND

更新日期：2004-10-01 00:00:00

abstract：:A 5 year old female child presented with a psoas haematoma as the first manifestation of haemophilia B. Molecular genetic studies were performed to investigate the inheritance of the disorder and the mechanisms by which females may express the haemophilia B phenotype are discussed. ...

journal_title：Postgraduate medical journal

authors： Palmer S,Standen GR,Yates P,Oakhill A

更新日期：1994-11-01 00:00:00

abstract：PURPOSE OF THE STUDY:This study aims to describe all unsolicited electronic invitations received from potential predatory publishers or fraudulent conferences over a 12-month period following the first publication as a corresponding author of a junior academician. STUDY DESIGN:Unsolicited invitations received at an in...

journal_title：Postgraduate medical journal

authors： Mercier E,Tardif PA,Moore L,Le Sage N,Cameron PA

更新日期：2018-02-01 00:00:00

abstract：:The Chancellor of the Exchequer's recent announcements to devolve decision making power from Whitehall to 30 English regions provide a challenge to use devolution to deliver more favourable health outcomes. However evaluation of devolved health models internationally is scarce, because it is rarely considered. Evidenc...

journal_title：Postgraduate medical journal

authors： Doyle Y,Johnstone P

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Following the National Chemotherapy Advisory Group report, calling for better management of patients with cancer admitted acutely to hospital, Clatterbridge Cancer Centre, with Merseyside and Cheshire Cancer Network, implemented an acute oncology service (AOS) for the region's seven acute trusts. STUDY DESI...

journal_title：Postgraduate medical journal

authors： Neville-Webbe HL,Wong H,Marshall E

更新日期：2016-11-01 00:00:00

abstract：:Three patients with lung carcinoid related Cushing's syndrome (LCRCS) treated at Frenchay Hospital, Bristol between 1984 and 1994 are described. The first patient presented with hyperpigmentation 13 years after bilateral adrenalectomy. The second patient had no recurrence or metastases 14 years after removal of a typi...

journal_title：Postgraduate medical journal

authors： Amer KM,Ibrahim NB,Forrester-Wood CP,Saad RA,Scanlon M

更新日期：2001-07-01 00:00:00

abstract：:The introduction of spiral technology to computed tomography (CT) scanners in the late 1980s has revolutionised the field of CT. Spiral CT offers definite practical benefits over conventional scanners and has expanded the role of CT through the development of new scanning techniques. CT scanning now rivals magnetic re...

journal_title：Postgraduate medical journal

authors： Kearney SE,Garvey CJ

更新日期：1998-02-01 00:00:00

abstract：:The gastric acid response and the buffer capacity of the stomach were measured in 30 control subjects and 22 duodenal ulcer patients in response to a masticatory (solid) and a non-masticatory (homogenized) meal having the same chemical composition. The peak acid output values were equal after a masticatory and after a...

journal_title：Postgraduate medical journal

authors： Dubey P,Nundy S

更新日期：1984-04-01 00:00:00

abstract：:Serum concentrations of LH, FSH, testosterone and prolactin were measured in patients with hypertension treated with propranolol (34 cases), methyldopa (13 cases), and methyldopa + propranolol (11 cases). The results were compared with those obtained in 18 controls (hospital out-patients). There were no differences in...

journal_title：Postgraduate medical journal

authors： Taylor RG,Crisp AJ,Hoffbrand BI,Maguire A,Jacobs HS

更新日期：1981-07-01 00:00:00

abstract：:Eight patients with steroid-sensitive nephrotic syndrome which frequently relapsed despite cyclophosphamide treatment were given cyclosporin A (7.5 mg/kg/day to 10 mg/kg/day) for 8 to 12 weeks. Six had minimal change glomerulonephritis and two had focal segmental glomerulonephritis. Cyclosporin A was given to 5 patien...

journal_title：Postgraduate medical journal

authors： Chan MK,Cheng IK

更新日期：1987-09-01 00:00:00

abstract：:The role of prostaglandins in inflammation is still disputed. Some workers have attempted to fit prostaglandins into a simple model, i.e. inflammatory leads to chemical mediator leads to vascular response. Recent work has shown that this approach may be misleading. An alternative model is proposed, involving the inter...

journal_title：Postgraduate medical journal

authors： Williams TJ

更新日期：1977-11-01 00:00:00

abstract：PURPOSE OF THE STUDY:To explore which factors increase the likelihood of being deemed appointable to core anaesthesia training in the UK and whether those factors subsequently predict performance in postgraduate training. STUDY DESIGN:Observational study linking UK medical specialty recruitment data with postgraduate ...

journal_title：Postgraduate medical journal

authors： Aslet M,Paton LW,Gale T,Tiffin PA

更新日期：2020-01-01 00:00:00

abstract：:We report a case of severe chronic iron deficiency anaemia secondary to blood loss from gastric angiodysplasia. The clinical features, diagnosis and management of this uncommon condition are discussed. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Millar AB

更新日期：1987-10-01 00:00:00

abstract：:A deceased 79 year old man with a permanent cardiac pacemaker was due to be cremated, but the pacemaker generator was not detectable by palpation. A hand held metal detector to locate the device so that it could be extracted before cremation. ...

journal_title：Postgraduate medical journal

authors： Gale CP,Mulley GP

更新日期：2005-03-01 00:00:00

abstract：:Although contrast angiography is important in the diagnosis and treatment of atherosclerotic disease, it does have limitations. Intracoronary ultrasound more accurately assesses the amount of atherosclerosis and has given us new insights into the pathophysiology of coronary plaque accumulation and remodelling. It also...

journal_title：Postgraduate medical journal

authors： Hammond C,Causer JP,Perry RA

更新日期：1998-08-01 00:00:00

abstract：:Two patients with nephrotic syndrome developed fatal fulminant hepatitis B following withdrawal of prednisolone or cyclophosphamide. Immunosuppressive therapy probably enhanced hepatitis B virus (HBV) replication and widespread infection of hepatocytes; its withdrawal permitted a return of immune competence resulting ...

journal_title：Postgraduate medical journal

authors： Onwubalili JK

更新日期：1988-04-01 00:00:00

abstract：:A patient is described with severe haemorrhage from a lumbar artery following percutaneous renal biopsy. The exact source of haemorrhage in this previously unreported complication proved difficult to locate even at surgical exploration. ...

journal_title：Postgraduate medical journal

authors： Jamison MH,Coward RA

更新日期：1985-01-01 00:00:00

abstract：:Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical disease and the occurrence of asymptomatic shedding. The lack of ea...

journal_title：Postgraduate medical journal

authors： Paz-Bailey G,Ramaswamy M,Hawkes SJ,Geretti AM

更新日期：2008-06-01 00:00:00

abstract：:A woman presented with painful enlargement of her parotid and submandibular glands. She was shown to have the previously unreported combination of idiopathic thrombocytopenic purpura, Sjögren's syndrome, Hashimoto's disease, and myasthenia gravis. Parotid gland biopsy and bone marrow examination showed the presence of...

journal_title：Postgraduate medical journal

authors： Savage AW,Shareef DS,Maher EJ,Bennett MH,Thomas DJ

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:To determine the utility of a novel Paediatric Consultation Assessment Tool (PCAT). DESIGN:Developed to measure clinicians' communication behaviour with children and their parents/guardian, PCAT was designed according to consensus guidelines and refined at a number of stages. Volunteer clinicians provided vi...

journal_title：Postgraduate medical journal

authors： Howells RJ,Davies HA,Silverman JD,Archer JC,Mellon AF

更新日期：2010-10-01 00:00:00

abstract：:Prostate cancer is receiving ever more publicity with the result that more men are having their prostate specific antigen checked and a greater proportion of men are diagnosed with potentially curable localised disease. Advances in the therapeutic modalities including radical surgery, external beam radiotherapy, and b...

journal_title：Postgraduate medical journal

authors： Bott SR,Birtle AJ,Taylor CJ,Kirby RS

更新日期：2003-10-01 00:00:00

abstract：:Hypertension is the most common chronic disease in the West Indies, and is a major health problem today being among the 10 most common causes of death in the English-speaking territories of the region. Most patients have essential hypertension. Renal failure, stroke, and cardiac failure are the most common complicatio...

journal_title：Postgraduate medical journal

authors： Grell GA

更新日期：1983-10-01 00:00:00

abstract：:Prostatic involvement is an unusual complication of Wegener's granulomatosis. We report two cases with this complication and emphasize the importance of recognizing this manifestation in diagnosis and management of the disease condition. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Woolf A,Falzon M

更新日期：1987-01-01 00:00:00

abstract：INTRODUCTION:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been caused the greatest pandemic of our century. Many of the deaths related to it are due to a systemic inflammatory response, which has been called 'cytokine storm'. OBJECTIVES:We developed a comprehensive review of the pathophysiology mec...

journal_title：Postgraduate medical journal

authors： Mélo Silva Júnior ML,Souza LMA,Dutra REMC,Valente RGM,Melo TS

更新日期：2020-10-02 00:00:00