Localized fibrous mesothelioma of the mediastinum devoid of pleural connections.

abstract：:Weekly low dose methotrexate is an established treatment for rheumatoid arthritis, but its use in elderly people has not been adequately examined. The aim of this study was to evaluate its safety in elderly patients with rheumatoid arthritis. A retrospective review of the clinical records of rheumatoid arthritis patie...

journal_title：Postgraduate medical journal

authors： Hirshberg B,Muszkat M,Schlesinger O,Rubinow A

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Circulating nitric oxide (NO) and lipid levels are closely associated with coronary artery disease (CAD). It is unclear whether the rs1799983 polymorphism in endothelial nitric oxide synthase (NOS3) gene is associated with plasma levels of NO and lipids. This systematic review and meta-analysis (Preferred Re...

journal_title：Postgraduate medical journal

authors： Luo Z,Jia A,Lu Z,Muhammad I,Adenrele A,Song Y

更新日期：2019-07-01 00:00:00

abstract：:A patient with the unusual post mortem finding of myocardial metastatic carcinoid tumour without classical valvular or endocardial carcinoid disease is described. This rare occurrence may represent an aggressive type of carcinoid tumour, with metastatic disease occurring before the development of classical fibrous val...

journal_title：Postgraduate medical journal

authors： Davis G,Birbeck K,Roberts D,Naqvi N

更新日期：1996-12-01 00:00:00

abstract：:Head injury from physical abuse is unfortunately a common occurrence in our society. It is a major cause of mortality and long-term physical and psychological disability in children. Diagnosis of non-accidental head injury may be difficult, as most infants present with non-specific clinical findings and without extern...

journal_title：Postgraduate medical journal

authors： Rajaram S,Batty R,Rittey CD,Griffiths PD,Connolly DJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a chronic, multisystem disease characterised by non-necrotising granulomatous inflammation of unknown aetiology. Most commonly, the lungs, lymph nodes, skin and eyes are affected in sarcoidosis; however, nervous system involvement occurs in approximately 5%-15% of cases. Any part of the nervou...

journal_title：Postgraduate medical journal

authors： Radwan W,Lucke-Wold B,Robadi IA,Gyure K,Roberts T,Bhatia S

更新日期：2017-07-01 00:00:00

abstract：:This is a case report of a 67 year old man who presented with a fluctuating level of consciousness and myoclonic jerks caused in part by hypercalcaemia. The diagnosis of cerebral neoplastic angioendotheleosis was only made later on brain biopsy and is the first report of the occurrence of hypercalcaemia in neoplastic ...

journal_title：Postgraduate medical journal

authors： Wierzbicki AS,Gibbs JM,Lidov HG,Lolin Y,Thomas PK

更新日期：1991-06-01 00:00:00

abstract：:We report the development of synchronous bilateral carpal tunnel syndrome in a woman with metastatic colorectal cancer, undergoing treatment with recombinant interleukin 2. A carpal tunnel decompression was carried out on the hand which was more severely affected, with a gradual recovery in median nerve function. To t...

journal_title：Postgraduate medical journal

authors： Heys SD,Mills KL,Eremin O

更新日期：1992-07-01 00:00:00

abstract：:A patient with Laurence-Moon-Biedl syndrome and nephrotic range proteinuria is presented. Radiological investigation of the urinary tract revealed clubbed calyces but no evidence of obstruction or vesicoureteric reflux. Renal biopsy revealed occasional sclerotic glomeruli, extensive foot-process fusion and segmental g...

journal_title：Postgraduate medical journal

authors： Cheng IK,Chan KW,Chan MK,Kung A,Ma J,Wang C

更新日期：1988-08-01 00:00:00

abstract：:Shaken baby syndrome is the most common cause of death or serious neurological injury resulting from child abuse. It is specific to infancy, when children have unique anatomic features. Subdural and retinal haemorrhages are markers of shaking injury. An American radiologist, John Caffey, coined the name whiplash shake...

journal_title：Postgraduate medical journal

authors： Blumenthal I

更新日期：2002-12-01 00:00:00

abstract：:A patient with calcific constrictive pericarditis due to rheumatoid arthritis is presented: the literature reveals only one previous case which was attributed to the long duration of the rheumatoid arthritis. ...

journal_title：Postgraduate medical journal

authors： Manji H,Raven P

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:Increased serum amyloid A (SAA) levels have been investigated in various human malignancies, but a consistent perspective has not been established to date. This study systematically reviewed the association between SAA levels and cancers. METHODS:Cochrane Library, PubMed and Embase were carefully searched fo...

journal_title：Postgraduate medical journal

authors： Zhou J,Sheng J,Fan Y,Zhu X,Tao Q,He Y,Wang S

更新日期：2018-09-01 00:00:00

abstract：:A previously healthy 17 year old boy had Staphylococcus aureus endocarditis presenting as acute scrotal pain. There was no trauma or evidence of scrotal or epididymal infection. The pain subsided after therapy for endocarditis was started. ...

journal_title：Postgraduate medical journal

authors： Watanakunakorn C

更新日期：1987-07-01 00:00:00

abstract：:Digoxin has been a key therapeutic for heart failure and atrial tachyarrhythmias for over 200 years following Withering's groundbreaking work depicting the therapeutic benefit of the common botanical foxglove in his 1785 monograph. The use of digoxin preceded any randomised evidence or even basic understanding of its ...

journal_title：Postgraduate medical journal

authors： Stucky MA,Goldberger ZD

更新日期：2015-09-01 00:00:00

abstract：:In severe appendicitis, the effect of a single intravenous dose of metronidazole (500 mg) was compared with cefoxitin (1 g). The antibiotics were given by random allocation once the diagnosis had been established at operation. In the metronidazole group, 5 out of 48 patients developed a wound infection whilst in hospi...

journal_title：Postgraduate medical journal

authors： Corder AP,Bates T,Prior JE,Harrison M,Donaldson PJ

更新日期：1983-11-01 00:00:00

abstract：:A 61-year-old patient with treated Conn's syndrome due to multiple bilateral adrenocortical adenomata developed primary hyperparathyroidism. At operation, a parathyroid adenoma and a thyroid colloid nodule were found. Although adrenocortical adenomata and hyperplasia are common findings in multiple endocrine adenopath...

journal_title：Postgraduate medical journal

authors： Fertig A,Webley M,Lynn JA

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:The survival of whites who have been treated for pernicious anaemia (PA) is unaffected, apart from incurring a greater risk of gastric cancers. The long term outcome of PA in Chinese is unknown. METHODS:A hospital based prospective longitudinal study of Chinese PA patients was conducted. Patients with known...

journal_title：Postgraduate medical journal

authors： Chan JC,Liu HS,Kho BC,Lau TK,Li VL,Chan FH,Leong IS,Pang HK,Lee CK,Liang YS

更新日期：2008-12-01 00:00:00

abstract：:The use of sulphasalazine in inflammatory bowel disease is often limited by intolerance or allergy. In previous studies 5-aminosalicylic acid (5ASA), the active ingredient of sulphasalazine, coated with an acrylic resin, has been shown to be as effective as sulphasalazine in maintaining remission. In this study coated...

journal_title：Postgraduate medical journal

authors： Donald IP,Wilkinson SP

更新日期：1985-12-01 00:00:00

abstract：:Six cases of tuberculous meningitis, all occurring in patients over the age of 65, are described. All patients presented with an acute illness, primarily with a confusional state. Headache was a symptom in only two patients and the cases were not confined to ethnic minority groups. The mortality was 50%. ...

journal_title：Postgraduate medical journal

authors： Dixon PE,Hoey C,Cayley AC

更新日期：1984-09-01 00:00:00

abstract：:We report a 44 year old man who developed external ophthalmoplegia and predominantly respiratory, truncal and bulbar weakness with brisk reflexes, histological evidence of an inflammatory myopathy and a high titre of acetylcholine receptor antibodies, one month after starting hydroxyurea and allopurinol for chronic my...

journal_title：Postgraduate medical journal

authors： Bergin PS,Gale AN

更新日期：1993-04-01 00:00:00

abstract：:A case of cervical osteoid osteoma is reported, with a brief account of the diagnosis and treatment of these lesions. Cervical osteoid osteoma is rare but its pattern of presentation varies little and it should therefore be possible to suspect it on clinical grounds alone. Bone scanning is now regarded as more efficie...

journal_title：Postgraduate medical journal

authors： Walker AP

更新日期：1980-10-01 00:00:00

abstract：:Defence against the reactive oxidants produced during aerobic metabolism is a complex process and is provided by a system of enzymes and antioxidant compounds capable of preventing excess radical production, neutralising free radicals and repairing the damage caused by them. Regulation of the antioxidant system must p...

journal_title：Postgraduate medical journal

authors： Szaleczky E,Prechl J,Fehér J,Somogyi A

更新日期：1999-01-01 00:00:00

abstract：:Eosinophilic gastroenteritis is a condition characterised by eosinophilic infiltration of the gastrointestinal tract. Biliary obstruction is an unusual presentation. A case where the initial investigations were consistent with carcinoma of the head of pancreas but the resection specimen showed no malignancy is present...

journal_title：Postgraduate medical journal

authors： Christopher V,Thompson MH,Hughes S

更新日期：2002-08-01 00:00:00

abstract：:Studies on hypouricaemia observed in a patient with 48,XXYY syndrome revealed an abnormality in renal urate handling. His renal urate clearance was abnormally increased. Inosine administration and provocative tests using probenecid and pyrazinamide identified an isolated renal tubular abnormality with increased urate ...

journal_title：Postgraduate medical journal

authors： Nakajima H,Tajima K,Nakajima T,Iida S,Sumi S,Kono N,Moriwaki K,Nonaka K,Tarui S

更新日期：1986-03-01 00:00:00

abstract：:In congestive heart failure (CHF) both the sympathetic nervous system (SNS) and the renin-angiotensin-aldosterone-system (RAAS) are activated. Both phenomena are only of short-term benefit and inevitably detrimental with prolonged activation. There are many possibilities for interaction between the systems, in particu...

journal_title：Postgraduate medical journal

authors： van Zwieten PA,de Jonge A

更新日期：1986-01-01 00:00:00

abstract：:This review considers some of the more common problems in the interpretation of the results of biochemical tests and, where possible, highlights ways in which errors can be identified or avoided. ...

journal_title：Postgraduate medical journal

authors： Ayling RM

更新日期：2000-03-01 00:00:00

abstract：:Recurrence of adrenal cortical carcinoma 22 years after first presentation is reported in a 54-year-old woman with Cushing's syndrome. This tumour is normally associated with poor prognosis and prolonged survival is rare. Although the patient had remained well with apparent 'cure' in the intervening years, it is sugge...

journal_title：Postgraduate medical journal

authors： Shaw KM,Fisher C,Peters JL,Ross EJ

更新日期：1979-10-01 00:00:00

abstract：:Parasites in the human breast are uncommon but not rare. Cysticercus and filariasis in fine needle breast aspirates have been documented and their cytomorphology is well characterised. However, the host tissue response to these parasites and the factors responsible for their initiation are not clear. Over a 21 year pe...

journal_title：Postgraduate medical journal

authors： Sahai K,Kapila K,Verma K

更新日期：2002-03-01 00:00:00

abstract：PURPOSE OF STUDY:The aim of the study is to describe the prevalence of illicit drug use in England and Wales using data from the UK Survey of Non-Medical Use of Prescription Drugs (NMURx) programme and to compare against the well-established Crime Survey England and Wales (CSEW). The rationale is that recreational and ...

journal_title：Postgraduate medical journal

authors： Ng FL,Rockhill K,Black J,May KP,Whittington MD,Wood DM,Dargan PI,Green JL

更新日期：2018-11-01 00:00:00

abstract：:Two patients with lymphoedema of the legs developed recurrent respiratory infections and were found to have panhypogammaglobulinaemia. The early recognition and treatment of this form of immunity deficiency in patients with lymphoedema is important in order to prevent recurrent infections which could cause pulmonary d...

journal_title：Postgraduate medical journal

authors： Lozewicz S,Morris G,Garbett N,Browse N,Slavin B,Cole P

更新日期：1988-01-01 00:00:00

abstract：:A 63 year old man who suffered from syringomyelia related to post-meningitic spinal arachnoiditis caused by Candida tropicalis is reported. The clinical syndrome of syringomyelia developed gradually and a definite diagnosis was delayed for more than 10 years. The patient has partially recovered after surgical treatmen...

journal_title：Postgraduate medical journal

authors： Phanthumchinda K,Kaoropthum S

更新日期：1991-08-01 00:00:00