Alterations in enzymatic antioxidant defence in diabetes mellitus--a rational approach.

abstract：:Three cases of severe and irreversible alopecia occurring in patients with common variable immunodeficiency are described. In all three cases, hair loss developed after the diagnosis of immune deficiency; one of the patients also had extensive vitiligo. A fourth patient had vitiligo in the absence of alopecia. No chan...

journal_title：Postgraduate medical journal

authors： Spickett G,Prentice AG,Wallington T,Webster AD,Chapel H

更新日期：1991-03-01 00:00:00

abstract：:The painful pathological condition of the penis, priapism, is usually associated with serious destructive changes which lead to impotence if treatment is with-held or delayed. Conservative therapy is slow, uncertain and usually ineffective. Early surgical decompression of the corpora cavernosa, repeated if necessary, ...

journal_title：Postgraduate medical journal

authors： Ihekwaba FN,Lawani J

更新日期：1981-02-01 00:00:00

abstract：:Two patients with a rise in cardiac troponin T (cTnT) concentrations during the course of lobar pneumonia, without any evidence of acute coronary syndrome or renal failure, are presented. The increase in cTnT concentration is considered a highly sensitive marker of cardiac injury, although it may also rise in other co...

journal_title：Postgraduate medical journal

authors： Weinberg I,Cukierman T,Chajek-Shaul T

更新日期：2002-04-01 00:00:00

abstract：:Proper understanding of the pathological process of a ruptured plaque followed by thrombus formation remains the basis for rational therapy of cardiac ischaemia and myocardial infarction. With the advent of better thrombolytic regimens, improved direct reperfusion via angioplasty and streamlined recognition/admission ...

journal_title：Postgraduate medical journal

authors： Hugenholtz PG

更新日期：1994-01-01 00:00:00

abstract：:Bilateral subconjunctival haemorrhage was observed on 5 separate occasions in 4 patients presenting a fulminant form of acute severe asthma. Four of these episodes required ventilatory support. All patients recovered from their asthma attack after treatment with bronchodilators, corticosteroids, and oxygen. The incide...

journal_title：Postgraduate medical journal

authors： Rodriguez-Roisin R,Torres A,Agustí AG,Ussetti P,Agustí-Vidal A

更新日期：1985-07-01 00:00:00

abstract：:Five patients with apparent adverse cardiovascular effects of disopyramide are reveiwed. Attention is drawn to the following problems. (1) A vagolytic effect may produce a sinus tachycardia with wide QRS complexes due to aberrant conduction or intraventricular block superficially resembling a ventricular tachycardia, ...

journal_title：Postgraduate medical journal

authors： Warrington SJ,Hamer J

更新日期：1980-04-01 00:00:00

abstract：:We report the case of a 66 year old woman with clinical manifestations of giant-cell arteritis, positive temporal artery biopsy and excellent response to prednisone, who developed massive cerebral infarcts after 5 days of treatment. Computed tomographic and magnetic resonance imaging scans revealed multiple infarcts i...

journal_title：Postgraduate medical journal

authors： Collazos J,García-Moncó C,Martín A,Rodriguez J,Gómez MA

更新日期：1994-03-01 00:00:00

abstract：:A 63 year old woman had been intensively treated for recurrent carcinoma of the neck. Following acute vascular surgery of the carotid artery, she developed the vasodilatory type of the carotid sinus syndrome. The presentation of this type of the syndrome was remarkable, since it is usually associated with primary or m...

journal_title：Postgraduate medical journal

authors： Dees A,Baatenburg de Jong RJ,Meeuwis CA,de Boer MF,de Leeuw PW

更新日期：1992-06-01 00:00:00

abstract：:We report the development of synchronous bilateral carpal tunnel syndrome in a woman with metastatic colorectal cancer, undergoing treatment with recombinant interleukin 2. A carpal tunnel decompression was carried out on the hand which was more severely affected, with a gradual recovery in median nerve function. To t...

journal_title：Postgraduate medical journal

authors： Heys SD,Mills KL,Eremin O

更新日期：1992-07-01 00:00:00

abstract：:A case of Peutz-Jeghers syndrome with polyps in the gall bladder is presented. No previous description of this finding has been reported. The literature regarding known sites of polyposis in this condition is reviewed. ...

journal_title：Postgraduate medical journal

authors： Foster DR,Foster DB

更新日期：1980-05-01 00:00:00

abstract：:Isolated left ventricular non-compaction is a rare, morphologically distinct primary genetic cardiomyopathy, which was first described in children, but is becoming increasingly recognised in adults. The most common clinical manifestations include heart failure, arrhythmias and embolic events, and in children it may be...

journal_title：Postgraduate medical journal

authors： Nair SB,Khattar RS

更新日期：2009-04-01 00:00:00

abstract：:Bile acid, neutral sterol and faecal fat excretion was studied over a period of 9 weeks in a group of 16 healthy subjects before, during and after administration of fenfluramine. Statistical analysis revealed a significant increase in bile acid excretion during the drug phase (P less than 0.02); and during recovery pe...

journal_title：Postgraduate medical journal

authors： Sian MS,Rains AJ

更新日期：1979-03-01 00:00:00

abstract：:A patient with occult pancreatic carcinoma associated with recurrent acute pancreatitis is reported. Endoscopic retrograde cholangiopancreatography after the first attack was normal, the diagnosis being made at repeat examination 10 months later. ...

journal_title：Postgraduate medical journal

authors： Wilson C,Imrie CW

更新日期：1986-08-01 00:00:00

abstract：:The treatment of renal anaemia by recombinant human erythropoietin (EPO) is now well established. Several studies have examined the pharmacokinetics and efficacy of the drug given intravenously, intraperitoneally and subcutaneously and there is increasing evidence that the subcutaneous route has several advantages inc...

journal_title：Postgraduate medical journal

authors： Macdougall IC,Hutton RD,Coles GA,Williams JD

更新日期：1991-01-01 00:00:00

abstract：:Coronary heart disease, especially when it affects younger individuals, tends to cluster in families. Known risk factors occur in 50-75% of patients with myocardial infarction. Yet commonly occurring risk factors are not strongly inherited, and the familial aggregation of coronary heart diseas may not be attributable ...

journal_title：Postgraduate medical journal

authors： Epstein FH

更新日期：1976-08-01 00:00:00

abstract：:Seventy-eight clinically euthyroid patients with atrial dysrhythmias, either established or paroxysmal, and sixty-three patients in sinus rhythm with coronary disease were screened for hyperthyroidism using thyroid function tests including the thyroid-stimulating hormone (TSH) response to thyrotrophin-releasing hormon...

journal_title：Postgraduate medical journal

authors： Symons C,Myers A,Kingstone D,Boss M

更新日期：1978-10-01 00:00:00

abstract：:We report the case of a 58 year old man in whom an unusually prolonged infection with Toxoplasma gondii was the presenting feature of an underlying non-Hodgkin's lymphoma. This case demonstrates the particular usefulness of the IgM ELISA test in monitoring disease activity. ...

journal_title：Postgraduate medical journal

authors： Dudley NJ,Balfour AH

更新日期：1988-11-01 00:00:00

abstract：:Tissue auto-antibodies were investigated in fifty-one patients (twenty-five female, twenty-six male) receiving practolol for ischaemic heart disease or dysrhythmias and compared with those found in 204 patients (fifty-eight female, 146 male) with ischaemic heart disease who did not receive practolol. Antinuclear facto...

journal_title：Postgraduate medical journal

authors： Jachuck SJ,Stephenson J,Bird T,Jackson FS,Clark F

更新日期：1977-02-01 00:00:00

abstract：:Heatstroke following vigorous exercise is reported in a young male. Severe hepatic and renal failure resulted but the patient completely recovered following treatment by active measures to reduce his core temperature. ...

journal_title：Postgraduate medical journal

authors： Fidler S,Fagan E,Williams R,Dewhurst I,Cory CE

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Following the National Chemotherapy Advisory Group report, calling for better management of patients with cancer admitted acutely to hospital, Clatterbridge Cancer Centre, with Merseyside and Cheshire Cancer Network, implemented an acute oncology service (AOS) for the region's seven acute trusts. STUDY DESI...

journal_title：Postgraduate medical journal

authors： Neville-Webbe HL,Wong H,Marshall E

更新日期：2016-11-01 00:00:00

abstract：INTRODUCTION:Potentially inappropriate medication (PIM) prescribing is a global problem. Limited data are available on the prevalence of PIMs in elderly patients with chronic kidney disease (CKD). We examined the PIM prevalence in elderly patients with CKD, the most common drugs implicated and the levels of polypharmac...

journal_title：Postgraduate medical journal

authors： Jones SA,Bhandari S

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:To determine whether exocrine pancreatic function is impaired in patients with coeliac disease (CD) in our population and to evaluate its clinical importance. METHODS:Pancreatic exocrine function was determined by measuring faecal elastase-1 (FE) concentration. CD was diagnosed by serological testing using ...

journal_title：Postgraduate medical journal

authors： Vujasinovic M,Tepes B,Volfand J,Rudolf S

更新日期：2015-09-01 00:00:00

abstract：:A 72 year old man developed acute myeloblastic leukaemia two years after he had been treated with local curative therapy and chemotherapy for a solitary plasma cytoma of the ilium. ...

journal_title：Postgraduate medical journal

authors： Maharaj D,Dolan G

更新日期：1986-12-01 00:00:00

abstract：:Four cases of severe osteolysis of bones subsequent to camel bite are described. The first had osteolysis of the ribs with traumatic diaphragmatic hernia. Two cases had similar appearances of gross osteolysis of the shafts of the radius and ulna, whilst one had osteolysis of the humeral shaft. The similarities in the ...

journal_title：Postgraduate medical journal

authors： al-Boukai AA,Hawass NE,Patel PJ,Kolawole TM

更新日期：1989-12-01 00:00:00

abstract：:Upper gastrointestinal bleeding is one of the commonest emergencies encountered by general physicians. Once haemodynamic stability has been achieved, therapeutic endoscopy is vital in control and arrest of bleeding. Various methods are available and the evidence is reviewed as to the most optimal approach. Clinical pa...

journal_title：Postgraduate medical journal

authors： Arasaradnam RP,Donnelly MT

更新日期：2005-02-01 00:00:00

abstract：:Venepuncture is commonly regarded as a trivial procedure allocated to the most junior medical staff. The result of this policy is that junior doctors are required to perform a minimally invasive procedure on consenting patients without any structured venepuncture training or assessment. Consequently, inexperienced doc...

journal_title：Postgraduate medical journal

authors： McConnell AA,Mackay GM

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Essential Skills in the Management of Surgical Cases (ESMSC) is a novel 3-day international undergraduate surgical masterclass. Its current curriculum (Cores integrated for Research-Ci4R) is built on a tetracore, multiclustered architecture combining high-fidelity and low-fidelity simulation-based learning (...

journal_title：Postgraduate medical journal

authors： Sideris M,Hanrahan J,Tsoulfas G,Theodoulou I,Dhaif F,Papalois V,Papagrigoriadis S,Velmahos G,Turner P,Papalois A

更新日期：2018-05-01 00:00:00

abstract：:The use of self-expanding metal stents can markedly improve the care of patients with inoperable oesophageal malignancy. The stents can be easily introduced without the need for general anaesthesia. They have fewer complications during insertion than rigid stents and fewer complications than laser therapy. With these ...

journal_title：Postgraduate medical journal

authors： Murphy GJ

更新日期：1995-08-01 00:00:00

abstract：:A 59 year old woman presented with acute onset of fever, chills, diaphoresis, vague chest discomfort, and was found to be hypotensive and tachypnoeic. An electrocardiogram demonstrated sinoatrial block with a junctional rhythm between 50 and 80 beats/min. All cultures were negative and imaging studies unrevealing. Her...

journal_title：Postgraduate medical journal

authors： Medarov B,Tongia S,Rossoff L

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Previous research has shown that sicker patients are less satisfied with their healthcare, but specific effects of adverse health outcomes have not been investigated. The present study aimed to assess whether patients who experience adverse outcomes, in hospital or after discharge, differ in their evaluation...

journal_title：Postgraduate medical journal

authors： Marang-van de Mheen PJ,van Duijn-Bakker N,Kievit J

更新日期：2008-02-01 00:00:00