Isolated left ventricular non-compaction: an emerging cause of heart failure in adults.

Abstract:

:Isolated left ventricular non-compaction is a rare, morphologically distinct primary genetic cardiomyopathy, which was first described in children, but is becoming increasingly recognised in adults. The most common clinical manifestations include heart failure, arrhythmias and embolic events, and in children it may be associated with facial dysmorphisms and Wolff-Parkinson-White syndrome. Misdiagnosis may occur through lack of awareness of the condition, but with increased vigilance detailed cardiac imaging can reliably differentiate isolated left ventricular non-compaction from other pathological causes of left ventricular dysfunction. This is important because the condition may be associated with significant morbidity and mortality, and genetic counselling and echocardiographic screening of first-degree relatives is recommended to detect asymptomatic cases.

journal_name

Postgrad Med J

authors

Nair SB,Khattar RS

doi

10.1136/pgmj.2008.070144

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

202-7

issue

1002

eissn

0032-5473

issn

1469-0756

pii

85/1002/202

journal_volume

85

pub_type

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