Cyclosporin A in steroid-sensitive nephrotic syndrome with frequent relapses.

abstract：:Various tumours, in particular lymphomas, have been reported in association with azathioprine treatment, both after renal transplantation and in other conditions. A case is reported here of acute myeloid leukaemia associated with azathioprine therapy for rheumatoid arthritis, and this is now the third case reported in...

journal_title：Postgraduate medical journal

authors： Gilmore IT,Holden G,Rodan KS

更新日期：1977-03-01 00:00:00

abstract：:We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide. We describe a possible drug interaction between these two drugs and recommend that they should only be used together with c...

journal_title：Postgraduate medical journal

authors： Webberley MJ,Murray JA

更新日期：1989-12-01 00:00:00

abstract：:Although recognized since the 1930s, slow infections have only recently received considerable attention. There are three types, group A (related to the type C RNA viruses), group B (bizarre agents such as scrapie and kuru) and group C (viruses such as measles which normally produce acute infections but which are behav...

journal_title：Postgraduate medical journal

authors： Sutton RN

更新日期：1979-02-01 00:00:00

abstract：:The recognition and treatment of depression is a challenging area of clinical practice, especially in primary care where there are many patients with various presentations and a multitude of causes for distress. The prevalence of depression is increasing, and it is predicted to become second only to ischaemic heart di...

journal_title：Postgraduate medical journal

authors： Lester H,Howe A

更新日期：2008-10-01 00:00:00

abstract：:A 12 year old boy presenting with hypercalcaemia (calcium 3.25 mmol/l) and osteopaenia with multiple osteolytic lesions was found to have acute lymphoblastic leukaemia without lymph-adenopathy or organomegaly. Hypercalcaemia is a rare feature of acute leukaemia, but the patients previously described all show very simi...

journal_title：Postgraduate medical journal

authors： Soni PN

更新日期：1993-06-01 00:00:00

abstract：:The case of a woman with a large benign villous papilloma of the rectum, presenting with sodium and water depletion and later complicated by persistent hypokalaemia, is described. The patient also suffered from primary hypogonadism and diabetes. ...

journal_title：Postgraduate medical journal

authors： Bamford JK,Galbraith HJ,Pender BW

更新日期：1965-04-01 00:00:00

abstract：:Erythromelalgia is an unusual condition characterized by attacks of burning pain in the hands and feet with local congestion and increased skin temperature. We report a case of erythromelalgia, with transient hypertension and elevated urinary catecholamines successfully treated by hypnotherapy. Such an association has...

journal_title：Postgraduate medical journal

authors： Chakravarty K,Pharoah PD,Scott DG,Barker S

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:This explorative study was triggered by the '#hellomynameis' campaign initiated by Dr Kate Granger in the UK. Our objectives were twofold: first, to measure rates of introduction in an Irish hospital setting by both consultant and non-consultant hospital doctors. Second to establish whether such practices we...

journal_title：Postgraduate medical journal

authors： Gillen P,Sharifuddin SF,O'Sullivan M,Gordon A,Doherty EM

更新日期：2018-04-01 00:00:00

abstract：:The incidence, predisposing factors, management and outcome of toxic megacolon (TM) has been reviewed in 65 cases of severe ulcerative colitis (UC) and compared in 2 successive 6-year periods before and after January, 1973. Nineteen episodes of TM occurred in 18 patients. Despite a conscious aim towards earlier surger...

journal_title：Postgraduate medical journal

authors： Muscroft TJ,Warren PM,Asquith P,Montgomery RD,Sokhi GS

更新日期：1981-04-01 00:00:00

abstract：OBJECTIVE:Since many years, teaching and training in communication skills are cornerstones in the medical education curriculum. Although video recording in a real-time consultation is expected to positively contribute to the learning process, research on this topic is scarce. This study will focus on the feasibility an...

journal_title：Postgraduate medical journal

authors： Eeckhout T,Gerits M,Bouquillon D,Schoenmakers B

更新日期：2016-08-01 00:00:00

abstract：:We report four cases of Bartter's syndrome in two consecutive generations of an Irish family. Diagnoses were made on the basis of characteristic clinical features, blood and urine biochemistry with additional evidence from renal biopsy in one case. The aetiology, treatment and inheritance of the syndrome are discussed...

journal_title：Postgraduate medical journal

authors： Crowe P,Ahmad A,O'Byrne K,Cullen MJ

更新日期：1993-10-01 00:00:00

abstract：:The clinical features of 62 cases of computerized axial tomography scan-proved cerebral haemorrhage and 81 cases of cerebral infarction in the carotid territory have been compared in a retrospective case note survey. The clinical features which can help in making the distinction between haemorrhage and infarction at t...

journal_title：Postgraduate medical journal

authors： Harrison MJ

更新日期：1980-09-01 00:00:00

abstract：:The mechanisms, clinical features and management of the various forms of urticaria are discussed. The importance of histamine receptors, complement and the kinin cascade are reviewed. ...

journal_title：Postgraduate medical journal

authors： Taaffe A

更新日期：1977-12-01 00:00:00

abstract：:Two female patients who suffered from drug-induced thrombocytopenic purpura and subendocardial myocardial infarction are presented. One of them died from cerebral haemorrhage and diffuse subendocardial punctate haemorrhages were found at post-mortem. The abnormal haemostasis which is associated with thrombocytopenia m...

journal_title：Postgraduate medical journal

authors： Fireman Z,Yust I,Zahavi J,Kahn Y,Abramov LA

更新日期：1979-01-01 00:00:00

abstract：:Forty-five healthy men aged 21-34 years took part in a double-blind, parallel-group, placebo-controlled study of the effects of 28 days' treatment with lornoxicam 4 mg twice daily or indomethacin 50 mg twice daily on faecal blood loss and the endoscopic appearances of gastric and duodenal mucosa. After an initial endo...

journal_title：Postgraduate medical journal

authors： Warrington SJ,Debbas NM,Farthing M,Horton M,Johnston A,Thillainayagam A,Turner P,Ferber H

更新日期：1990-08-01 00:00:00

abstract：:Phyllodes tumours are rare fibroepithelial lesions that account for less than 1% of all breast neoplasms. With the non-operative management of fibroadenomas widely adopted, the importance of phyllodes tumours today lies in the need to differentiate them from other benign breast lesions. All breast lumps should be trip...

journal_title：Postgraduate medical journal

authors： Parker SJ,Harries SA

更新日期：2001-07-01 00:00:00

abstract：:Sixty-nine infants were examined who presented with rectal bleeding in the first month of life. In 64% of these children no cause was found. Infantile diarrhoea, haemorrhagic disease of the newborn and anal fissure were the most common diagnoses made. The mortality in the entire group was less than 3%. It is concluded...

journal_title：Postgraduate medical journal

authors： Levene MI

更新日期：1979-01-01 00:00:00

abstract：:This study examines clinical features of late onset anorexia nervosa. This involved the scrutiny of a large database of patients with anorexia nervosa comprising data gathered at standardized initial assessments over the period 1960-1990. Patients with a late onset were compared to other selected patient samples. The ...

journal_title：Postgraduate medical journal

authors： Joughin NA,Crisp AH,Gowers SG,Bhat AV

更新日期：1991-11-01 00:00:00

abstract：:It is a tragedy that morphine is scarcely available for between 1.3 and 2.5 billion people whilst 3.5 million cancer patients suffer needlessly. In only 10 countries is its consumption rising, in many more only codeine consumption shows an increase, and in many areas even in the Western world prescribing is grossly li...

journal_title：Postgraduate medical journal

authors： Doyle D

更新日期：1991-01-01 00:00:00

abstract：PURPOSE OF THE STUDY:Genome-wide association studies have revealed an association of ADAMTS7 polymorphisms with the risk of cardiovascular diseases. Nonetheless, the role of ADAMTS7 polymorphisms on myocardial infarction (MI) risk remains poorly understood. Here, we aim to evaluate the effect of ADAMTS7 tag single nucl...

journal_title：Postgraduate medical journal

authors： Liang LL,Zhou YL,Cheng J,Xiao YT,Tang ZB,Liu SM,Lian JC,Wang XX,Liu X,Xiong XD

更新日期：2019-09-01 00:00:00

abstract：:To determine the prevalence and extent of autonomic neuropathy amongst Africans with insulin-dependent diabetes mellitus (IDDM), we investigated 50 such patients at our clinic. Mean age (+/- 1 s.d.) was 26 +/- 6 years, male:female ratio was equal (25M:25F) and duration of diabetes was 4.0 +/- 3.0 years. A battery of s...

journal_title：Postgraduate medical journal

authors： Tuch PS,Gill GV,Huddle KR

更新日期：1994-03-01 00:00:00

abstract：:Oral administration of 1 g of acetazolamide to 8 normal subjects studied at sea level and in normoxia caused an acute increase in cerebral blood flow (CBF). During the subsequent prolonged oral treatment with 1 g of acetazolamide daily, CBF returned to normal within 2 days. The alveolar CO2 tension decreased gradually...

journal_title：Postgraduate medical journal

authors： Lassen NA,Friberg L,Kastrup J,Rizzi D,Jensen JJ

更新日期：1987-03-01 00:00:00

abstract：:Ruptured abdominal aortic aneurysm currently accounts for about 1 in 200 deaths and is a critical surgical emergency with an average hospital mortality of 50%. The combination of acute massive haemorrhage in an elderly patient with pre-existing medical disease is highly lethal and a major challenge for any health care...

journal_title：Postgraduate medical journal

authors： Brimacombe J,Berry A

更新日期：1994-04-01 00:00:00

abstract：:Four studies have been carried out on propofol in this department, one being part of a multicentre trial. The minimum induction dose in unpremedicated patients was found to be 2.5 mg/kg. Propofol has been shown to be an acceptable induction agent, although with an incidence of pain on injection which is much higher wh...

journal_title：Postgraduate medical journal

authors： Grounds RM,Morgan M,Lumley J

更新日期：1985-01-01 00:00:00

abstract：:Antibiotic resistance is an important concern for patients, physicians, healthcare managers, and policymakers. Inappropriate antimicrobial prescribing fuels the evolution of resistance, while poor basic hygiene facilitates the spread of resistant microbes between patients and healthcare staff. The development of infec...

journal_title：Postgraduate medical journal

authors： Barlow G,Nathwani D

更新日期：2005-11-01 00:00:00

abstract：:Coeliac disease is exacerbated by wheat gluten. A review of methods for the purification, identification and quantitation of wheat proteins to investigate coeliac disease is presented. Recent developments including amino acid sequencing and expression of wheat protein peptides in E. coli should permit characterization...

journal_title：Postgraduate medical journal

authors： Ciclitira PJ,Ellis HJ

更新日期：1987-09-01 00:00:00

abstract：:Treatment of angina with a single drug often proves unsatisfactory because of dose-related unwanted effects or occasionally an adverse effect on the angina. A combination of a beta-blocking agent and a calcium antagonist drug might achieve satisfactory control of angina at acceptable doses of each drug. Widespread app...

journal_title：Postgraduate medical journal

authors： Geddes JS

更新日期：1983-01-01 00:00:00

abstract：:In 40 hypertensive patients continuous ECG recording was done before and after 30 days treatment with indapamide 2.5 mg. There was no change in heart rate. In addition, the incidence of extrasystoles was not changed in patients in whom the ECG was normal before treatment (30 cases) or in 8 of the 10 patients who had a...

journal_title：Postgraduate medical journal

authors： Haiat R,Lellouch A,Lanfranchi J,Witchitz S

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Despite the importance of timely management of patients with inflammatory arthritis (IA), delays exist in its diagnosis and treatment. OBJECTIVE:To perform a systematic literature review to identify strategies addressing these delays to inform an American College of Rheumatology (ACR)/European League Agains...

journal_title：Postgraduate medical journal

authors： Villeneuve E,Nam JL,Bell MJ,Deighton CM,Felson DT,Hazes JM,McInnes IB,Silman AJ,Solomon DH,Thompson AE,White PH,Bykerk VP,Emery P

更新日期：2013-04-01 00:00:00

abstract：:Thirty patients who had undergone major abdominal surgery were randomly assigned to a continuous infusion of either 0.45 mg meptazinol/kg/hr or 0.3 mg pethidine/kg/hr. Analgesia was assessed by rating scale, ranging from 0 (no pain) to 10 (unbearable pain), and by questionnaire. Respiration rate was closely monitored ...

journal_title：Postgraduate medical journal

authors： Church JJ

更新日期：1983-01-01 00:00:00