Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin.

abstract：:It is a tragedy that morphine is scarcely available for between 1.3 and 2.5 billion people whilst 3.5 million cancer patients suffer needlessly. In only 10 countries is its consumption rising, in many more only codeine consumption shows an increase, and in many areas even in the Western world prescribing is grossly li...

journal_title：Postgraduate medical journal

authors： Doyle D

更新日期：1991-01-01 00:00:00

abstract：:Micronutrients play a central part in metabolism and in the maintenance of tissue function. An adequate intake therefore is necessary, but provision of excess supplements to people who do not need them may be harmful. Single micronutrient deficiency states are comparatively easily recognised and treated. Subclinical d...

journal_title：Postgraduate medical journal

authors： Shenkin A

更新日期：2006-09-01 00:00:00

abstract：:For millennia, the smile has been recognised as a powerful communication device, offering benefits to both giver and receiver with few drawbacks. A sign of compassion, empathy and friendliness, smiling can benefit healthcare professionals and their patients, helping to build a relationship of trust. But beware the fal...

journal_title：Postgraduate medical journal

authors： Beamish AJ,Foster JJ,Edwards H,Olbers T

更新日期：2019-02-01 00:00:00

abstract：:A previously fit man developed psittacosis with marked cerebellar symptoms and signs. He was febrile but not confused, and he responded rapidly to treatment with erythromycin. Even if respiratory symptoms are minimal, psittacosis and other atypical pneumonias should be considered in any patient presenting with fever a...

journal_title：Postgraduate medical journal

authors： Shee CD

更新日期：1988-05-01 00:00:00

abstract：:A 5-year-old girl presented with a swelling in the right axilla from which Mycobacterium avium-intracellulare was cultured. The gland was excised and she made an uneventful recovery. ...

journal_title：Postgraduate medical journal

authors： Colley EW,Cox RA

更新日期：1983-09-01 00:00:00

abstract：:We describe the cases of two young women who died due to air embolism during sexual intercourse early in the puerperium. ...

journal_title：Postgraduate medical journal

authors： Batman PA,Thomlinson J,Moore VC,Sykes R

更新日期：1998-10-01 00:00:00

abstract：:The empty sella syndrome (ESS) presents a varied clinical and radiographic picture. It may remain asymptomatic or may stimulate an intrasellar growth thereby causing diagnostic and therapeutic problems. An air encephalogram (AEG) is required for diagnosis. The purpose of this paper is to review the clinical and radiol...

journal_title：Postgraduate medical journal

authors： Sachdev Y,Evered DC,Appleby A,Hall R

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Primary percutaneous coronary intervention (PPCI) programmes vary in admission criteria from open referral to acceptance of electrocardiogram (ECG) protocol positive patients only. Rigid criteria may result in some patients with acutely occluded coronary arteries not receiving timely reperfusion therapy. OB...

journal_title：Postgraduate medical journal

authors： Apps A,Malhotra A,Tarkin J,Smith R,Kabir T,Lane R,Mason M,Ali O,Rogers P,Banya W,Whitbread M,Ilsley C,Dalby M

更新日期：2013-07-01 00:00:00

abstract：:Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical ...

journal_title：Postgraduate medical journal

authors： Mahy IR,Jennings KP

更新日期：1998-06-01 00:00:00

abstract：:Disc herniation at the thoracic the spine level is more common than generally thought. Localisation of pain may be vague and may erroneously point to cardiopulmonary, gastrointestinal, genito-urinary or even psychiatric disease. Magnetic resonance imaging is the investigation of choice, especially if spinal cord compr...

journal_title：Postgraduate medical journal

authors： Pal B,Johnson A

更新日期：1997-07-01 00:00:00

abstract：:Multiple lymphomatous polyposis is an uncommon but distinctive form of gastrointestinal lymphoma. Clinical symptoms may closely resemble those of colorectal carcinoma and diagnostic confusion may result. The condition has a characteristic pathological appearance and immunophenotype which is important in allowing disti...

journal_title：Postgraduate medical journal

authors： Carder PJ,Gouldesbrough DR

更新日期：1993-05-01 00:00:00

abstract：:Clinical, endocrinological and computed tomographic features of three patients with unusual manifestations or complications of craniofacial involvement of fibrous dysplasia are presented. One patient with polyostotic fibrous dysplasia presented in late pregnancy with acute onset of bilateral optic nerve compression an...

journal_title：Postgraduate medical journal

authors： Daly BD,Chow CC,Cockram CS

更新日期：1994-01-01 00:00:00

abstract：:Warfarin, a vitamin K antagonist, is the most widely used oral anticoagulant in the world. It is cheap and effective, but its use is limited in many patients by unpredictable levels of anticoagulation, which increases the risk of thromboembolic or haemorrhagic complications. It also requires regular blood monitoring a...

journal_title：Postgraduate medical journal

authors： Saraf K,Morris PD,Garg P,Sheridan P,Storey R

更新日期：2014-09-01 00:00:00

abstract：:An 8 month old Caucasian girl, with congenital central alveolar hypoventilation syndrome (Ondine's Curse), was discharged with her home ventilation managed by her parents. Her subsequent neurophysical development assessed at 22 months of age was satisfactory. ...

journal_title：Postgraduate medical journal

authors： Chang YL,Meerstadt PW

更新日期：1991-05-01 00:00:00

abstract：:The aortic root links the left ventricle and ascending aorta and functions as a support structure for the aortic valve. It can be affected by a variety of congenital and acquired conditions, some of which are potentially life threatening. Echocardiography and cardiac magnetic resonance imaging are established non-inva...

journal_title：Postgraduate medical journal

authors： Vargas HA,Hoey ET,Gopalan D,Agrawal SK,Screaton NJ,Gulati GS

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Previous research has shown that sicker patients are less satisfied with their healthcare, but specific effects of adverse health outcomes have not been investigated. The present study aimed to assess whether patients who experience adverse outcomes, in hospital or after discharge, differ in their evaluation...

journal_title：Postgraduate medical journal

authors： Marang-van de Mheen PJ,van Duijn-Bakker N,Kievit J

更新日期：2008-02-01 00:00:00

abstract：:Head injury from physical abuse is unfortunately a common occurrence in our society. It is a major cause of mortality and long-term physical and psychological disability in children. Diagnosis of non-accidental head injury may be difficult, as most infants present with non-specific clinical findings and without extern...

journal_title：Postgraduate medical journal

authors： Rajaram S,Batty R,Rittey CD,Griffiths PD,Connolly DJ

更新日期：2011-05-01 00:00:00

abstract：:Clomipramine may affect reproduction in male rats and dogs, while other psychotropic drugs can affect sperm motility in vitro. This study investigates the motility of hamster sperm and the fertilization of hamster eggs in vitro with epididymal sperm from alpha-chlorohydrin-pretreated males, and after preincubation wit...

journal_title：Postgraduate medical journal

authors： Stein DM,Schnieden H

更新日期：1980-01-01 00:00:00

abstract：:Rectal swabs obtained from 10 of 49 chronic-care geriatric patients were positive for Clostridium difficile, for a prevalence rate of 20.4%. Simultaneous sampling of 29 patients in an acute geriatric ward revealed four colonized patients, for a prevalence rate of 13.7%. A prospective study of C. difficile colonization...

journal_title：Postgraduate medical journal

authors： Rudensky B,Rosner S,Sonnenblick M,van Dijk Y,Shapira E,Isaacsohn M

更新日期：1993-01-01 00:00:00

abstract：AIMS:To review the clinical and pathological factors associated with fulminant amoebic colitis (FAC) requiring colonic resection and its outcome. METHODS:We retrospectively identified adult patients admitted to our centre between June 2007 and December 2011 with FAC who underwent colonic resection and were diagnosed w...

journal_title：Postgraduate medical journal

authors： Chaturvedi R,Gupte PA,Joshi AS

更新日期：2015-04-01 00:00:00

abstract：:Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal ...

journal_title：Postgraduate medical journal

authors： McRipley RJ,Erhard PJ,Schwind RA,Whitney RR

更新日期：1979-09-01 00:00:00

abstract：:This paper reviews the development of cerebral scintigraphy from its early days of planar imaging with simple technetium-99m labelled compounds to the recent revival of the technique in the form of positron-emission and single-photon emission tomography. A short explanation of instrumentation and radiopharmaceuticals ...

journal_title：Postgraduate medical journal

authors： Shepstone BJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Colonoscopy is the best way of imaging the colon with concurrent biopsy and treatment. However it is expensive, requires full bowel preparation, and carries a risk of complications. Flexible sigmoidoscopy is an alternative way to investigate symptoms that raise the suspicion of a lesion of the rectum or left...

journal_title：Postgraduate medical journal

authors： Papagrigoriadis S,Arunkumar I,Koreli A,Corbett WA

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Repetitive laboratory testing in stable patients is low-value care. Electronic health record (EHR)-based interventions are easy to disseminate but can be restrictive. OBJECTIVE:To evaluate the effect of a minimally restrictive EHR-based intervention on utilisation. SETTING:One year before and after interve...

journal_title：Postgraduate medical journal

authors： Chin KK,Krishnamurthy A,Zubair T,Ramaswamy T,Hom J,Maggio P,Shieh L

更新日期：2021-02-01 00:00:00

abstract：:The Wolff-Parkinson-White syndrome can rarely present with pre-excited atrial fibrillation. In this condition the short refractory period of the accessory pathway can lead to rapid atrioventricular conduction. There is then a danger that at high heart rates the irregular broad complex tachycardia that results can dete...

journal_title：Postgraduate medical journal

authors： Adlam D,Azeem T

更新日期：2003-05-01 00:00:00

abstract：:A 12 year old boy presenting with hypercalcaemia (calcium 3.25 mmol/l) and osteopaenia with multiple osteolytic lesions was found to have acute lymphoblastic leukaemia without lymph-adenopathy or organomegaly. Hypercalcaemia is a rare feature of acute leukaemia, but the patients previously described all show very simi...

journal_title：Postgraduate medical journal

authors： Soni PN

更新日期：1993-06-01 00:00:00

abstract：:We present a 78-year-old woman with clinical acute hypopituitarism in whom pathologic findings showed lymphocytic hypophysitis and retroperitoneal fibrosis. Lymphocytic hypophysitis should be included in the differential diagnosis of hypopituitarism at any age. The association with idiopathic retroperitoneal fibrosis ...

journal_title：Postgraduate medical journal

authors： Alvarez A,Cordido F,Sacristán F

更新日期：1997-11-01 00:00:00

abstract：:The implementation of modernizing medical careers (MMC) has resulted in some specialties being allocated very inexperienced trainees such as ophthalmology. We aim to describe the process of implementation of MMC and how it may affect the service provision in smaller specialities such as ophthalmology. A methodical app...

journal_title：Postgraduate medical journal

authors： Patel N,Zia R,Dewitd D,Morris S,Ionides A

更新日期：2007-12-01 00:00:00

abstract：:The gross and microscopic features of an unusual case of neurocutaneous melanosis are described. This is an example of the rare association between a primary central nervous system malignant melanoma and a giant congenital melanocytic naevus of 'bathing trunk' distribution. ...

journal_title：Postgraduate medical journal

authors： Salisbury JR,Rose PE

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:The survival of whites who have been treated for pernicious anaemia (PA) is unaffected, apart from incurring a greater risk of gastric cancers. The long term outcome of PA in Chinese is unknown. METHODS:A hospital based prospective longitudinal study of Chinese PA patients was conducted. Patients with known...

journal_title：Postgraduate medical journal

authors： Chan JC,Liu HS,Kho BC,Lau TK,Li VL,Chan FH,Leong IS,Pang HK,Lee CK,Liang YS

更新日期：2008-12-01 00:00:00