Slow viruses and chronic disease of the central nervous system.

abstract：:Two different doses of cefaclor advanced formulation (AF), a new sustained-release formulation of cefaclor, were compared with the regular formulation of cefaclor for efficacy and safety in the treatment of uncomplicated cystitis and asymptomatic bacteriuria. A 7-day course of treatment was used, and the trials were d...

journal_title：Postgraduate medical journal

authors： Hamilton-Miller JM,Iravani A,Brumfitt W,Byers KS,Dere WH

更新日期：1992-01-01 00:00:00

abstract：:Warfarin, a vitamin K antagonist, is the most widely used oral anticoagulant in the world. It is cheap and effective, but its use is limited in many patients by unpredictable levels of anticoagulation, which increases the risk of thromboembolic or haemorrhagic complications. It also requires regular blood monitoring a...

journal_title：Postgraduate medical journal

authors： Saraf K,Morris PD,Garg P,Sheridan P,Storey R

更新日期：2014-09-01 00:00:00

abstract：:A case of Peutz-Jeghers syndrome with polyps in the gall bladder is presented. No previous description of this finding has been reported. The literature regarding known sites of polyposis in this condition is reviewed. ...

journal_title：Postgraduate medical journal

authors： Foster DR,Foster DB

更新日期：1980-05-01 00:00:00

abstract：:Herpes simplex encephalitis may be underdiagnosed in Britain. We report eight patients treated at one hospital over three years. Fever, impaired consciousness or focal neurological signs were seen in all patients at presentation but herpes simplex encephalitis was rarely considered as the initial diagnosis. The electr...

journal_title：Postgraduate medical journal

authors： Gulliford MC,Chandrasekera CP,Cooper RA,Murphy RP

更新日期：1987-12-01 00:00:00

abstract：:Antenatal appendicular perforation leading to localized meconium peritonitis and intestinal obstruction is reported in a premature neonate. The baby was successfully treated by a limited ileocaecal resection. ...

journal_title：Postgraduate medical journal

authors： Narasimharao KL,Mitra SK,Pathak IC

更新日期：1987-11-01 00:00:00

abstract：:A 5 year old female child presented with a psoas haematoma as the first manifestation of haemophilia B. Molecular genetic studies were performed to investigate the inheritance of the disorder and the mechanisms by which females may express the haemophilia B phenotype are discussed. ...

journal_title：Postgraduate medical journal

authors： Palmer S,Standen GR,Yates P,Oakhill A

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Aortic dissection is a life-threatening cardiovascular disease with high mortality. Little is known about comparisons of the clinical characteristics or the factors that influence the long-term prognosis of Chinese patients with aortic dissection with and without Marfan syndrome (MFS). METHODS:The authors s...

journal_title：Postgraduate medical journal

authors： Linggen G,Lin Z,Xiaohan F,Haiying W,Xianliang Z,Rutai H

更新日期：2011-05-01 00:00:00

abstract：:Various tumours, in particular lymphomas, have been reported in association with azathioprine treatment, both after renal transplantation and in other conditions. A case is reported here of acute myeloid leukaemia associated with azathioprine therapy for rheumatoid arthritis, and this is now the third case reported in...

journal_title：Postgraduate medical journal

authors： Gilmore IT,Holden G,Rodan KS

更新日期：1977-03-01 00:00:00

abstract：:Heart involvement by amyloid deposition remains the most challenging of all organ sytems that may become involved, in what is generally a systemic disease. The correct diagnosis of amyloid type is critical to selection of the appropriate and wide range of therapies. The treatment of amyloid heart disease comprises two...

journal_title：Postgraduate medical journal

authors： Dubrey SW

更新日期：2012-12-01 00:00:00

abstract：:Mathematical techniques are well suited to analysis of growth data. In the past there has been much emphasis on the mathematical description of shape and changes of shape as exemplified by the allometric equation. More recently these methods have been less popular and shape analysis has been handled largely by modern ...

journal_title：Postgraduate medical journal

authors： Preece MA

更新日期：1978-01-01 00:00:00

abstract：:Two-hundred and nine patients were entered into a prospective, randomized trial in order to determine whether a vertical or transverse abdominal incision is the more satisfactory in producing sound wounds. Ninety-six patients were randomized between paramedian and transverse incisions, and followed up for at least 1 y...

journal_title：Postgraduate medical journal

authors： Ellis H,Coleridge-Smith PD,Joyce AD

更新日期：1984-06-01 00:00:00

abstract：:The implementation of modernizing medical careers (MMC) has resulted in some specialties being allocated very inexperienced trainees such as ophthalmology. We aim to describe the process of implementation of MMC and how it may affect the service provision in smaller specialities such as ophthalmology. A methodical app...

journal_title：Postgraduate medical journal

authors： Patel N,Zia R,Dewitd D,Morris S,Ionides A

更新日期：2007-12-01 00:00:00

abstract：:Both the quality and the quantity of food ingested are relevant to the genesis of risk factors for coronary heart disease and the two are inseparable. Nevertheless they have a major common pathway through hypertension, which may well be the most important consequence of a high-protein, high-carbohydrate, high-fat, hig...

journal_title：Postgraduate medical journal

authors： Brook CG

更新日期：1978-03-01 00:00:00

abstract：:Ultrasound guidance has been reported to facilitate the performance of lumbar punctures (LPs). However, the use of ultrasound guidance has not yet received consistent conclusions. We performed a systematic review and meta-analysis to determine the efficacy of ultrasound-guided LPs. PubMed, Embase and the Cochrane Libr...

journal_title：Postgraduate medical journal

authors： Shu L,Huang J,Liu JC

更新日期：2021-01-01 00:00:00

abstract：:The mechanisms of the antinociceptive action of flupirtine, a novel non-opioid analgesic, were investigated in animals. It was found that this effect could be abolished by pre-treatment with reserpine. Furthermore, it could be dose-dependently antagonized by yohimbine and changes in the EEG of the rat observed after a...

journal_title：Postgraduate medical journal

authors： Szelenyi I,Nickel B

更新日期：1987-01-01 00:00:00

abstract：:A patient with the unusual post mortem finding of myocardial metastatic carcinoid tumour without classical valvular or endocardial carcinoid disease is described. This rare occurrence may represent an aggressive type of carcinoid tumour, with metastatic disease occurring before the development of classical fibrous val...

journal_title：Postgraduate medical journal

authors： Davis G,Birbeck K,Roberts D,Naqvi N

更新日期：1996-12-01 00:00:00

abstract：:Programmed cell death (PCD) is an important terminal pathway for cells of multicellular organisms, and is involved in a variety of biological events that include morphogenesis, maintenance of tissue homeostasis, and elimination of harmful cells. Dysfunction of PCD leads to various diseases in humans, especially variou...

journal_title：Postgraduate medical journal

authors： Sun Y,Peng ZL

更新日期：2009-03-01 00:00:00

abstract：:Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage as defined by the UICC-TNM and American Joint Committee on Cancer classifications. Tumour extent, lymph node status, tumour grade and the assessment of lymphatic and venous invasion are still the most important morphological progn...

journal_title：Postgraduate medical journal

authors： Zlobec I,Lugli A

更新日期：2008-08-01 00:00:00

abstract：:The first case of the Zollinger-Ellison syndrome treated from the outset continuously for more than a year with the histamine H2-receptor antagonist cimetidine is reported. Symptomatic response has been dramatic and sustained, marked endoscopic improvement has been observed with healing of oesophageal, gastric and sto...

journal_title：Postgraduate medical journal

authors： Larkworthy W,Davies HL

更新日期：1977-12-01 00:00:00

abstract：:Splenic peliosis was identified at necropsy in a 62-year-old woman receiving continuous ambulatory peritoneal dialysis for end-stage renal failure, and erythropoietin therapy for uraemia and anaemia. The immediate cause of death was arrhythmia related to ischaemic heart disease, following an episode of intramuscular h...

journal_title：Postgraduate medical journal

authors： Lam KY,Chan AC,Chan TM

更新日期：1995-08-01 00:00:00

abstract：:In 40 hypertensive patients continuous ECG recording was done before and after 30 days treatment with indapamide 2.5 mg. There was no change in heart rate. In addition, the incidence of extrasystoles was not changed in patients in whom the ECG was normal before treatment (30 cases) or in 8 of the 10 patients who had a...

journal_title：Postgraduate medical journal

authors： Haiat R,Lellouch A,Lanfranchi J,Witchitz S

更新日期：1981-01-01 00:00:00

abstract：:Based on "second look" pelviscopic control in 438 cases of pelvic endometrosis, additional hormonal antigonadotrophin therapy with danazol represents the most effective treatment for endometriosis. The rationale is well explained by Dmowski and Scommegna (1976). As endocrine treatment alone cannot control severe cases...

journal_title：Postgraduate medical journal

authors： Mettler L,Semm K

更新日期：1979-01-01 00:00:00

abstract：:Psychosis is common in Parkinson's disease (PD), particularly in its later stages. The symptoms range from comparatively minor illusions, vivid dreams, and occasional, non-disturbing visual hallucinations to frank psychosis. The pathogenesis of psychosis in PD is not fully known. Management of psychosis in PD requires...

journal_title：Postgraduate medical journal

authors： Thanvi BR,Lo TC,Harsh DP

更新日期：2005-10-01 00:00:00

abstract：:This is a case report of a boy who presented with unilateral foot drop approximately 1 year after traumatic injury from skateboarding. Exploratory surgical operation was eventually performed, and histological examination of the surgical specimen revealed leprous peripheral neuropathy of the peroneal nerve. The patient...

journal_title：Postgraduate medical journal

authors： Choe W

更新日期：1994-02-01 00:00:00

abstract：:The NHS 'Choose Wisely' campaign places greater emphasis on the clinician-patient dialogue. Patients are often in receipt of their laboratory data and want to know whether they are normal. But what is meant by normal? Comparator data, to a measured value, are colloquially known as the 'normal range'. It is often assum...

journal_title：Postgraduate medical journal

authors： Whyte MB,Kelly P

更新日期：2018-11-01 00:00:00

abstract：:Strips form canine saphenous veins were incubated with (3H)-noradrenaline and mounted for superfusion. 5-Hydroxytryptamine (5-HT inhibited the release of tritium caused by sustained electrical stimulation (2 Hz, 150 mA, 0.1 msec) being about 10 times more potent than noradrenaline. 5-HT inhibited contractions induced ...

journal_title：Postgraduate medical journal

authors： Müller-Schweinitzer E

更新日期：1981-01-01 00:00:00

abstract：:This report describes the case history of a middle-aged lady who presented with symptoms and signs over one year leading to a diagnosis of multiple sclerosis. During one of her relapses, she developed trismus--an association that has not been described before in multiple sclerosis. ...

journal_title：Postgraduate medical journal

authors： D'Costa DF,Vania AK,Millac PA

更新日期：1990-10-01 00:00:00

abstract：:Amniotic fluid embolism (AFE) associated with disseminated intravascular clotting (DIC) is usually fatal. Such a combination generally occurs at the term of pregnancy or in the immediate postpartum period. A case of AFE with DIC following a hypertonic-saline-induced abortion, is reported. The patient was in the midtri...

journal_title：Postgraduate medical journal

authors： Ballas S,Lessing JB,Michowitz M

更新日期：1983-02-01 00:00:00

abstract：:A young woman with a previous history of anorexia nervosa presented with severe finger clubbing. Urine samples intermittently contained significant amounts of aspartylglucosamine. Liver biopsy showed abnormal cytoplasmic inclusions in phagocytic cells. The patient was found to be abusing senna laxative. ...

journal_title：Postgraduate medical journal

authors： Malmquist J,Ericsson B,Hultén-Nosslin MB,Jeppsson JO,Ljungberg O

更新日期：1980-12-01 00:00:00

abstract：:We describe two cases of digoxin toxicity presenting with clinical and electroencephalographic evidence of encephalopathy without other features of digoxin toxicity. ...

journal_title：Postgraduate medical journal

authors： Greenaway JR,Abuaisha B,Bramble MG

更新日期：1996-06-01 00:00:00