Destructive bone lesions in primary amyloidosis.

abstract：:Vasoconstriction increases impedance to ventricular ejection and impairs the performance of the dilated myopathic heart. Vasodilator drug therapy by reducing vascular resistance, increasing vascular compliance and increasing vascular capacitance improves cardiac function and relieves the signs and symptoms of congesti...

journal_title：Postgraduate medical journal

authors： Cohn JN

更新日期：1986-06-01 00:00:00

abstract：:Digoxin has been a key therapeutic for heart failure and atrial tachyarrhythmias for over 200 years following Withering's groundbreaking work depicting the therapeutic benefit of the common botanical foxglove in his 1785 monograph. The use of digoxin preceded any randomised evidence or even basic understanding of its ...

journal_title：Postgraduate medical journal

authors： Stucky MA,Goldberger ZD

更新日期：2015-09-01 00:00:00

abstract：:A previously undescribed type of congenital abdominal wall hernia is described. Presentation was with the symptoms and signs of subacute large bowel obstruction. The diagnosis was suggested by barium enema and confirmed at laparotomy. ...

journal_title：Postgraduate medical journal

authors： Siriwardena AK

更新日期：1989-02-01 00:00:00

abstract：:Tuberculous infection of the oesophagus is rare. This is confirmed by our present review of cases managed in our teaching hospitals over a period of 18 years which uncovered only 11 patients. The main presentation is that of dysphagia whose algorithm of investigation should seek to differentiate tuberculosis from carc...

journal_title：Postgraduate medical journal

authors： Mokoena T,Shama DM,Ngakane H,Bryer JV

更新日期：1992-02-01 00:00:00

abstract：:Autoimmune pancreatitis (AIP) is a form of chronic pancreatitis characterised clinically by frequent presentation with obstructive jaundice, histologically by a lymphoplasmacytic infiltrate with fibrosis, and therapeutically by a dramatic response to steroids. When so defined, AIP can be sub-classified into two subtyp...

journal_title：Postgraduate medical journal

authors： Kamisawa T,Chari ST,Lerch MM,Kim MH,Gress TM,Shimosegawa T

更新日期：2014-01-01 00:00:00

abstract：:The morphological features of endomyocardial fibrosis and Löffler's endocarditis are described. Sixteen cases of the chronic stage of Löffler's endocarditis were compared with pathological material of thirty-two patients with endomyocardial fibrosis. No morphological differences were noted. It is suggested that endomy...

journal_title：Postgraduate medical journal

authors： Olsen EG

更新日期：1977-09-01 00:00:00

abstract：:During the course of an obscure illness in a teenage girl it was eventually realized that the diagnosis was 'epidemic neuromyasthenia'. The illness which occurred between February and September 1976 was characterized by fatigue, pallor, headache, nuchal pain, alterations in mentation, dizziness, nausea and vomiting, p...

journal_title：Postgraduate medical journal

authors： Corridan JP

更新日期：1978-11-01 00:00:00

abstract：:Exercise is known to have a vast array of health benefits. It may however confer delirious effects on most body systems, with the cardiovascular system taking particular prominence. Athletes in particular are known to be at a higher risk for sudden cardiac death as a result of several cardiac adaptations which take pl...

journal_title：Postgraduate medical journal

authors： Abela M,Sammut L

更新日期：2017-12-01 00:00:00

abstract：:This paper reviews briefly the place of ipratropium bromide in the treatment of airways obstruction. Oxitropium bromide, a new quaternary ammonium compound derived from scopolamine was shown to be as effective a bronchodilator in a dose of 200 micrograms by inhalation as ipratropium bromide 80 micrograms in 20 patient...

journal_title：Postgraduate medical journal

authors： Anderson G

更新日期：1983-01-01 00:00:00

abstract：:Up to one fifth of patients who present to specialist clinics with seizures do not have epilepsy. The majority of such patients suffer from psychologically mediated episodes; dissociative seizures, often referred to as "non-epileptic seizures". This paper describes the diagnostic evaluation of seizure disorders, inclu...

journal_title：Postgraduate medical journal

authors： Mellers JD

更新日期：2005-08-01 00:00:00

abstract：:Rhabdomyolysis is a rare but potentially fatal complication of hyperosmolar states. We report a case of severe hyperosmolar non-ketotic diabetic coma causing rhabdomyolysis in a young man. Despite very high levels of creatine kinase there was no detectable myoglobinuria. Creatine kinase estimation should be a standard...

journal_title：Postgraduate medical journal

authors： Trump D,O'Hanlon S,Rinsler M,Sharp P

更新日期：1994-01-01 00:00:00

abstract：:Three patients are described in whom one or more carotid territory transient ischaemic attacks (TIAs) were preceded by sneezing, straining, or bending over. It is argued that the mechanism involved dislodgment of embolic material from the site of carotid atheroma. This mechanism should be considered as an alternative ...

journal_title：Postgraduate medical journal

authors： Harrison MJ

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:The prognostic value of serum uric acid (SUA) for incident acute coronary syndrome (ACS) in hypertensive subjects is uncertain. Therefore, the present study examined the association between SUA and incident ACS in a large cohort of Chinese hypertensive adults. METHODS:This was a retrospective cohort study, ...

journal_title：Postgraduate medical journal

authors： Shen G,Huang JY,Yu YL,Liu L,Chen CL,Zhang B,Huang YQ,Feng YQ

更新日期：2020-02-01 00:00:00

abstract：:We studied two sisters who developed large non-toxic goitres in adolescence. Deiodinase deficiency was diagnosed by a rapid thyroid uptake of radioactive iodine (RAI) at 2 hours associated with a marked fall in thyroidal 131I by 24 hours. Serial RAI scans in the second patient documented evolution of the iodine-defici...

journal_title：Postgraduate medical journal

authors： Hirsch HJ,Shilo S,Spitz IM

更新日期：1986-06-01 00:00:00

abstract：:A series of 8 adult patients with stable bronchial asthma and an established diagnois of essential hypertension (WHO I and II) was studied in a randomized double-blind cross-over study to assess the effect of captopril (50-100 mg/day) and verapamil (160-240 mg/day) on blood pressure, lung function and asthmatic sympto...

journal_title：Postgraduate medical journal

authors： Riska H,Stenius-Aaniala B,Sovijärvi AR

更新日期：1986-01-01 00:00:00

abstract：:The gastric acid response and the buffer capacity of the stomach were measured in 30 control subjects and 22 duodenal ulcer patients in response to a masticatory (solid) and a non-masticatory (homogenized) meal having the same chemical composition. The peak acid output values were equal after a masticatory and after a...

journal_title：Postgraduate medical journal

authors： Dubey P,Nundy S

更新日期：1984-04-01 00:00:00

abstract：:The case is reported of a patient presenting with recurrent acute myocardial infarction due to stent thrombosis resulting from possible clopidogrel resistance caused by interaction between clopidogrel and anti-tuberculosis drugs. A brief overview of drug interaction as a risk factor for clopidogrel resistance is given...

journal_title：Postgraduate medical journal

authors： Srinivasan M,Smith D

更新日期：2008-04-01 00:00:00

abstract：:A case of skin necrosis at the sites of injection of subcutaneous heparin is described. The patient went on to develop heparin-induced thrombocytopenia and pulmonary embolism. Review of the previously described cases of heparin-associated skin necrosis reveals that this sequence of events is not uncommon. ...

journal_title：Postgraduate medical journal

authors： Fowlie J,Stanton PD,Anderson JR

更新日期：1990-07-01 00:00:00

abstract：:Venepuncture is commonly regarded as a trivial procedure allocated to the most junior medical staff. The result of this policy is that junior doctors are required to perform a minimally invasive procedure on consenting patients without any structured venepuncture training or assessment. Consequently, inexperienced doc...

journal_title：Postgraduate medical journal

authors： McConnell AA,Mackay GM

更新日期：1996-01-01 00:00:00

abstract：:A patient with disseminated ovarian carcinoma presented with symptoms of hypocalcaemia secondary to hypomagnesaemia. The low serum magnesium (0.4 mmol/l) appeared to be due to renal leakage with no evidence of ureteric obstruction or hydronephrosis on intravenous urogram. Parathyroid hormone activity (serum levels and...

journal_title：Postgraduate medical journal

authors： Leese GP,Jung RT,Browning MC

更新日期：1993-07-01 00:00:00

abstract：AIMS:To review the clinical and pathological factors associated with fulminant amoebic colitis (FAC) requiring colonic resection and its outcome. METHODS:We retrospectively identified adult patients admitted to our centre between June 2007 and December 2011 with FAC who underwent colonic resection and were diagnosed w...

journal_title：Postgraduate medical journal

authors： Chaturvedi R,Gupte PA,Joshi AS

更新日期：2015-04-01 00:00:00

abstract：:Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage as defined by the UICC-TNM and American Joint Committee on Cancer classifications. Tumour extent, lymph node status, tumour grade and the assessment of lymphatic and venous invasion are still the most important morphological progn...

journal_title：Postgraduate medical journal

authors： Zlobec I,Lugli A

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The diagnosis of spinal tuberculosis (ST) is difficult and it commonly presents at an advanced stage. The management and follow up is complicated by a lack of guidance on the appropriate use and interpretation of spinal magnetic resonance studies (MR). AIMS:A retrospective study was performed at a UK centre...

journal_title：Postgraduate medical journal

authors： Cormican L,Hammal R,Messenger J,Milburn HJ

更新日期：2006-01-01 00:00:00

abstract：:A 33-year-old housewife with a 14-year history of relapsing polyneuropathy of unknown cause who has apparently responded to azathioprine therapy is described. The place of this form of treatment in idiopathic polyneuropathy is discussed. ...

journal_title：Postgraduate medical journal

authors： Pentland B

更新日期：1980-10-01 00:00:00

abstract：:Bilateral subconjunctival haemorrhage was observed on 5 separate occasions in 4 patients presenting a fulminant form of acute severe asthma. Four of these episodes required ventilatory support. All patients recovered from their asthma attack after treatment with bronchodilators, corticosteroids, and oxygen. The incide...

journal_title：Postgraduate medical journal

authors： Rodriguez-Roisin R,Torres A,Agustí AG,Ussetti P,Agustí-Vidal A

更新日期：1985-07-01 00:00:00

abstract：:Important implications for the recognition of iron deficiency anaemia include diagnosis and correction of underlying causes, most of which are identifiable, in the older patient, by means of conventional upper gastrointestinal endoscopy, and by colonoscopy. The aetiological search may, however, have to be widened to i...

journal_title：Postgraduate medical journal

authors： Jolobe OM

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:Effective communication is a vital part of good clinical care. Traditionally bleep systems have been used as the mainstay of communication. Mobile technology is increasingly seen as a quicker, easier and more reliable method of communication. Our objective was to assess the use of mobile devices within a typ...

journal_title：Postgraduate medical journal

authors： Martin G,Janardhanan P,Withers T,Gupta S

更新日期：2016-09-01 00:00:00

abstract：:We report a case of adult pyloric obstruction caused by the delayed presentation of a congenital gastric diverticulum. The derivation, classification and treatment of these abnormalities are discussed. ...

journal_title：Postgraduate medical journal

authors： Hale PC,O'Flynn WR

更新日期：1992-04-01 00:00:00

abstract：:Placebo, used here to mean an inert treatment given as if it was a real treatment, means lots of different things to different people. The structure of the article is that it begins by talking about the technical use of placebos in clinical trials, and the extent of the placebo response, then about the mechanism--"How...

journal_title：Postgraduate medical journal

authors： McQuay HJ,Moore RA

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:The WHO estimates that by 2020 two-thirds of the diseases worldwide will be the result of unhealthy lifestyle habits. Less than half of primary care physician graduates feel prepared to give lifestyle behaviour counselling. Our objective was to evaluate the impact of lifestyle medicine (LM) course on self-repor...

journal_title：Postgraduate medical journal

authors： Malatskey L,Bar Zeev Y,Tzuk-Onn A,Polak R

更新日期：2017-09-01 00:00:00