Prognostic and predictive factors in colorectal cancer.

abstract：:The majority of deaths in COPD are from cardiovascular causes. Several large randomized controlled trials demonstrate that inhaled anticholinergic agents ipratropium and tiotropium increase the risk of serious cardiovascular events, including cardiovascular mortality. Tiotropium Respimat is associated with a statistic...

journal_title：Postgraduate medical journal

authors： Singh S,Loke YK,Enright P,Furberg CD

更新日期：2014-04-01 00:00:00

abstract：:Exacerbations of chronic obstructive pulmonary disease impose a considerable burden of morbidity, mortality, and health care cost. Management guidelines outlining best practice, based largely on consensus expert opinion, were produced by a number of organisations during the last decade. Current interest in the field i...

journal_title：Postgraduate medical journal

authors： Hurst JR,Wedzicha JA

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Patients with irreversible chronic kidney disease who require dialysis immediately are a subset of ultra late referrals for whom the term chronic kidney disease presenting acutely might usefully be applied. Although well known to nephrologists and recognised as a specific group with considerable problems, li...

journal_title：Postgraduate medical journal

authors： Wolfe M,Almond A,Robertson S,Donaldson K,Isles C

更新日期：2010-07-01 00:00:00

abstract：:A case of hyperemesis gravidarum at 9 weeks' gestation is described for which no cause could initially be found. Intravenous feeding was needed as a life preserving measure and following improvement on this regime the patient went into a thyrotoxic crisis which was successfully diagnosed and treated. The continuing pr...

journal_title：Postgraduate medical journal

authors： Valentine BH,Jones C,Tyack AJ

更新日期：1980-10-01 00:00:00

abstract：:Episodic muscular weakness, commonly associated with alterations of serum potassium, is the cardinal feature of periodic paralysis. The combination of transient hyperkalaemia and rigors occurring during febrile episodes of malaria is suggested as the underlying cause which precipitated the muscular paralysis. Three pa...

journal_title：Postgraduate medical journal

authors： Senanayake N,Wimalawansa SJ

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Colonoscopy is the best way of imaging the colon with concurrent biopsy and treatment. However it is expensive, requires full bowel preparation, and carries a risk of complications. Flexible sigmoidoscopy is an alternative way to investigate symptoms that raise the suspicion of a lesion of the rectum or left...

journal_title：Postgraduate medical journal

authors： Papagrigoriadis S,Arunkumar I,Koreli A,Corbett WA

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF THE STUDY:Resistin, a recently discovered proinflammatory cytokine, has been strongly linked to kidney dysfunction. The aim of this study was to determine the relationship of serum resistin with serum cystatin C (sCysC) and albuminuria, two sensitive endogenous markers of renal function, in elderly male pati...

journal_title：Postgraduate medical journal

authors： Zhang M,Cui H,Zhu BP,Fu SH

更新日期：2015-03-01 00:00:00

abstract：:The most sensitive index of hepatic encephalopathy in 29 patients following a porta-caval shunt appeared to be the assessment of a close relative who had known the patient pre-operatively. They noticed that 19 of the 20 patients were mentally slower; 11 were markedly aggressive and 8 had become placid and uncaring abo...

journal_title：Postgraduate medical journal

authors： Gazzard BG,Price H,Dawson AM

更新日期：1986-03-01 00:00:00

abstract：:Patients with acquired von Willebrand disease may present with severe bleeding, which is usually difficult to manage. Adequate haemostasis in acquired von Willebrand disease may be achieved with the infusion of factor VIII/von Willebrand factor concentrates or with the administration of desmopressin. We report a case ...

journal_title：Postgraduate medical journal

authors： Van Genderen PJ,Papatsonis DN,Michiels JJ,Wielenga JJ,Stibbe J,Huikeshoven FJ

更新日期：1994-12-01 00:00:00

abstract：:Tobacco smoking contributes to about six million deaths per year and is predicted to increase in the future. Several pharmacological interventions are used for smoking cessation. Trials using nicotine replacement therapy (NRT) in acute coronary syndrome (ACS) showed inconclusive results. Furthermore, three trials usin...

journal_title：Postgraduate medical journal

authors： Chehab OM,Dakik HA

更新日期：2018-02-01 00:00:00

abstract：:Two different doses of cefaclor advanced formulation (AF), a new sustained-release formulation of cefaclor, were compared with the regular formulation of cefaclor for efficacy and safety in the treatment of uncomplicated cystitis and asymptomatic bacteriuria. A 7-day course of treatment was used, and the trials were d...

journal_title：Postgraduate medical journal

authors： Hamilton-Miller JM,Iravani A,Brumfitt W,Byers KS,Dere WH

更新日期：1992-01-01 00:00:00

abstract：:Stroke is a recognised complication of pregnancy, contributing to more than 12% of all maternal deaths. Estimated incidence rates vary considerably from 4.3 to 210 strokes per 100,000 deliveries. Atherosclerosis is rare in young adults, and so other causes of stroke become increasingly likely. Aetiological factors imp...

journal_title：Postgraduate medical journal

authors： Treadwell SD,Thanvi B,Robinson TG

更新日期：2008-05-01 00:00:00

abstract：:Colonic strictures are very common and are a frequent finding on double contrast barium examination; they very often reflect the presence of malignancy, diverticular disease, ischaemia, inflammatory bowel disease, and rarely mycobacterial disease. A case of mycobacterial disease mimicking malignancy is presented; this...

journal_title：Postgraduate medical journal

authors： Rees JR,Longstaff A,Rigby HL,Smith DL,Dixon AR

更新日期：2003-12-01 00:00:00

abstract：:There is an increasing awareness on the part both of the media and the profession of the need to co-operate in providing information and education on medical matters. This co-operation should be strongly encouraged. Where children are concerned the opportunities for education are great. ...

journal_title：Postgraduate medical journal

authors： Jolly H

更新日期：1978-03-01 00:00:00

abstract：INTRODUCTION:Women's participation in medicine has increased dramatically during the last 50 years, yet Office for National Statistics data (2016) regarding annual pay continue to show an unequivocal 34% deficit in female doctors' remuneration compared with their male counterparts. This study aimed to identify whether ...

journal_title：Postgraduate medical journal

authors： Brown C,Harries RL,Abdelrahman T,Thomas C,Pollitt MJ,Lewis WG

更新日期：2018-09-01 00:00:00

abstract：:Bilateral subconjunctival haemorrhage was observed on 5 separate occasions in 4 patients presenting a fulminant form of acute severe asthma. Four of these episodes required ventilatory support. All patients recovered from their asthma attack after treatment with bronchodilators, corticosteroids, and oxygen. The incide...

journal_title：Postgraduate medical journal

authors： Rodriguez-Roisin R,Torres A,Agustí AG,Ussetti P,Agustí-Vidal A

更新日期：1985-07-01 00:00:00

abstract：:Toxicity to digoxin was monitored in 437 consecutive recipients in a comprehensive drug surveillance programme, Adverse reactions developed in 19.5% and, in contrast to previous reports, were generally of a relatively benign nature. There were no drug-related deaths, but patients with adverse reactions spent longer in...

journal_title：Postgraduate medical journal

authors： Henry DA,Lowe JM,Lawson DA,Whiting B

更新日期：1981-06-01 00:00:00

abstract：:Paget's disease of bone is a relatively common condition in the UK affecting up to 5% of the population over the age of 55 years with particularly high prevalence in the North West of England. The majority of those affected are asymptomatic. Its precise cause remains unknown, and until recently, choice of treatment of...

journal_title：Postgraduate medical journal

authors： Ooi CG,Fraser WD

更新日期：1997-02-01 00:00:00

abstract：:By comparison with other calcium antagonist drugs, amlodipine has unique pharmacokinetic properties that are probably attributable to its chemical structure and positive ionic charge at physiological pH. Thus, amlodipine undergoes gradual absorption from the gastro-intestinal tract and is widely distributed throughout...

journal_title：Postgraduate medical journal

authors： Elliott HL,Meredith PA

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:How medical students learn and develop the characteristics associated with good teaching in medicine is not well known. Information about this process can improve the academic preparation of medical students for teaching responsibilities. The purpose of this study was to determine how different experiences cont...

journal_title：Postgraduate medical journal

authors： Henry BW,Haworth JG,Hering P

更新日期：2006-09-01 00:00:00

abstract：:We report a case of severe chronic iron deficiency anaemia secondary to blood loss from gastric angiodysplasia. The clinical features, diagnosis and management of this uncommon condition are discussed. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Millar AB

更新日期：1987-10-01 00:00:00

abstract：:Programmed cell death (PCD) is an important terminal pathway for cells of multicellular organisms, and is involved in a variety of biological events that include morphogenesis, maintenance of tissue homeostasis, and elimination of harmful cells. Dysfunction of PCD leads to various diseases in humans, especially variou...

journal_title：Postgraduate medical journal

authors： Sun Y,Peng ZL

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF THE STUDY:Iron deficiency anaemia (IDA) is associated with increased morbidity and mortality in heart failure patients. The aim of our audit was to evaluate the current practice in diagnosis and assessment of IDA in patients admitted with heart failure. STUDY DESIGN:We conducted a retrospective audit of pat...

journal_title：Postgraduate medical journal

authors： Simon S,Ioannou A,Deoraj S,Metaxa S,Mandal AKJ,Missouris CG

更新日期：2020-04-01 00:00:00

abstract：:The new UK Foundation Programme is competency based, with a trainee's progression dependent on achieving and demonstrating a range of competencies. However, we do not know whether all rotations, comprising different combinations of specialties, will enable the foundation programme trainees to acquire these competencie...

journal_title：Postgraduate medical journal

authors： Higgins R,Cavendish S

更新日期：2006-10-01 00:00:00

abstract：:Postherpetic neuralgia is defined as pain persisting, or recurring, at the site of shingles at least three months after the onset of the acute rash. Thus defined, at least half of shingles sufferers over the age of 65 years develop postherpetic neuralgia. In addition to increasing age, less important risk factors for ...

journal_title：Postgraduate medical journal

authors： Bowsher D

更新日期：1997-10-01 00:00:00

abstract：:During the course of an obscure illness in a teenage girl it was eventually realized that the diagnosis was 'epidemic neuromyasthenia'. The illness which occurred between February and September 1976 was characterized by fatigue, pallor, headache, nuchal pain, alterations in mentation, dizziness, nausea and vomiting, p...

journal_title：Postgraduate medical journal

authors： Corridan JP

更新日期：1978-11-01 00:00:00

abstract：:Left ventricular function was evaluated non-invasively in hypertensive patients treated with indapamide by means of echographically determined velocity of circumferential fibre shortening (VCF). A statistically significant reduction in mean systolic and diastolic blood pressure in both the standing and supine position...

journal_title：Postgraduate medical journal

authors： Horgan JH,O'Donovan A,Teo KK

更新日期：1981-01-01 00:00:00

abstract：:Rectal (both digital and rigid sigmoidoscopic) examination is an important part of the clinical examination. The aim of this study was to find out the opinions of the patients to this routine examination at the time of referral by their general practitioner and during their first hospital interview. Assessment of the ...

journal_title：Postgraduate medical journal

authors： Ng DP,Mayberry JF,McIntyre AS,Long RG

更新日期：1991-10-01 00:00:00

abstract：:Parasites in the human breast are uncommon but not rare. Cysticercus and filariasis in fine needle breast aspirates have been documented and their cytomorphology is well characterised. However, the host tissue response to these parasites and the factors responsible for their initiation are not clear. Over a 21 year pe...

journal_title：Postgraduate medical journal

authors： Sahai K,Kapila K,Verma K

更新日期：2002-03-01 00:00:00

abstract：:Tuberculosis of the appendix is rare. It is usually secondary to tuberculosis elsewhere in the abdomen. Tuberculosis of the appendix is not associated with any specific clinical features and diagnosis is revealed only after histopathological examination. Appendicectomy should be performed in all patients with abdomina...

journal_title：Postgraduate medical journal

authors： Singh MK,Arunabh,Kapoor VK

更新日期：1987-10-01 00:00:00