'Epidemic neuromyasthenia' in Southwest Ireland.

abstract：:Leg ulcer is a leading cause of morbidity among older subjects, especially women in the Western world. About 400 years BC, Hippocrates wrote, "In case of an ulcer, it is not expedient to stand, especially if the ulcer be situated on the leg". Hippocrates himself had a leg ulcer. The best treatment of any leg ulcer dep...

journal_title：Postgraduate medical journal

authors： Sarkar PK,Ballantyne S

更新日期：2000-11-01 00:00:00

abstract：:In this study we have examined the ability of senior house officers in the Accident and Emergency (A&E) Department to interpret electrocardiographs (ECGs) and tested the value of a single seminar and guidelines on interpretation. We prospectively audited ECG interpretation taken from notes over a two-month period and ...

journal_title：Postgraduate medical journal

authors： White T,Woodmansey P,Ferguson DG,Channer KS

更新日期：1995-03-01 00:00:00

abstract：PURPOSE:To determine the association between professors' self-perception of mentoring skills and their academic performance. DESIGN:Two hundred and fifteen professors from Imperial College London, the first Academic Health Science Centre (AHSC) in the UK, were surveyed. The instrument adopted was the Mentorship Skills...

journal_title：Postgraduate medical journal

authors： Athanasiou T,Patel V,Garas G,Ashrafian H,Shetty K,Sevdalis N,Panzarasa P,Darzi A,Paroutis S

更新日期：2016-10-01 00:00:00

abstract：:The interpretation of gastrin release is confused because of variation in the technique of the radioimmuoassay of gastrin, the lack of a standard stimulus for the release of gastrin and diversity in the method used to express the results. These problems have been analysed (a) by examining the cross-reactivity of three...

journal_title：Postgraduate medical journal

authors： Russel RC,Bloom SR,Fielding LP,Bryant MG

更新日期：1976-10-01 00:00:00

abstract：:Two cases of patients with ischaemic colitis requiring operative treatment are presented. Both had received a commonly used psychotropic drug in large dosage before the acute episode. Evidence is produced which may link the drugs used with the condition of ischaemic colitis. ...

journal_title：Postgraduate medical journal

authors： Gollock JM,Thomson JP

更新日期：1984-08-01 00:00:00

abstract：:This review presents our experience in the use of propranolol in the management of cardiac infarction. The drug has now been shown to have a definite place, not only in the prevention of cardiac infarction, but also in the treatment of some of the complications. The drug has also been advocated because it may minimiz...

journal_title：Postgraduate medical journal

authors： Sloman G,Hunt D,Ross D

更新日期：1976-01-01 00:00:00

abstract：:Three cases of severe and irreversible alopecia occurring in patients with common variable immunodeficiency are described. In all three cases, hair loss developed after the diagnosis of immune deficiency; one of the patients also had extensive vitiligo. A fourth patient had vitiligo in the absence of alopecia. No chan...

journal_title：Postgraduate medical journal

authors： Spickett G,Prentice AG,Wallington T,Webster AD,Chapel H

更新日期：1991-03-01 00:00:00

abstract：:Twelve healthy volunteers took part in a randomised, double-blind, balanced, cross-over study to investigate the effect of misoprostol on the pharmacokinetics of propranolol. The subjects took propranolol 80 mg twice daily by mouth plus either misoprostol 400 micrograms twice daily or placebo by mouth for 14.5 days, f...

journal_title：Postgraduate medical journal

authors： Bennett PN,Fenn GC,Notarianni LJ,Lee CE

更新日期：1991-05-01 00:00:00

abstract：:" Blo -Bag", a new disposable spacer device, has been tested in conjunction with Duovent metered dose inhaler. Duovent produced a significant bronchodilatation for the duration of the study. When delivered by the " Blo -Bag" it produced a significantly greater increase in peak expiratory flow rate than when delivered ...

journal_title：Postgraduate medical journal

authors： Woodcock A,Humberstone A,Kendall J,Pierce A

更新日期：1984-01-01 00:00:00

abstract：:Two cases of widespread cutaneous vasculitis are described in association with diltiazem, a recently introduced calcium antagonist. In both cases, spontaneous resolution occurred over several weeks following withdrawal of the drug. ...

journal_title：Postgraduate medical journal

authors： Sheehan-Dare RA,Goodfield MJ

更新日期：1988-06-01 00:00:00

abstract：:Vasoconstriction increases impedance to ventricular ejection and impairs the performance of the dilated myopathic heart. Vasodilator drug therapy by reducing vascular resistance, increasing vascular compliance and increasing vascular capacitance improves cardiac function and relieves the signs and symptoms of congesti...

journal_title：Postgraduate medical journal

authors： Cohn JN

更新日期：1986-06-01 00:00:00

abstract：:The reported impact of human monoclonal IgM antibody (HA1A) on the mortality rate from Gram-negative bacteraemia aroused considerable interest in its use in Glasgow Royal Infirmary. However, the commercial preparation of HA1A was extremely expensive. With this in mind, the Infirmary's Drugs and Therapeutics Committee ...

journal_title：Postgraduate medical journal

authors： Bell E,McCartney C

更新日期：1995-02-01 00:00:00

abstract：:Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised as a major public health burden. Large-scale epidemiological studies have demonstrated an independent relationship between OSAS and various cardiovascular disorders. The pathogenesis of cardiovascular complications in OSAS is not ...

journal_title：Postgraduate medical journal

authors： Ryan S,Taylor CT,McNicholas WT

更新日期：2009-12-01 00:00:00

abstract：:Exacerbations of chronic obstructive pulmonary disease impose a considerable burden of morbidity, mortality, and health care cost. Management guidelines outlining best practice, based largely on consensus expert opinion, were produced by a number of organisations during the last decade. Current interest in the field i...

journal_title：Postgraduate medical journal

authors： Hurst JR,Wedzicha JA

更新日期：2004-09-01 00:00:00

abstract：:This is a case report of a boy who presented with unilateral foot drop approximately 1 year after traumatic injury from skateboarding. Exploratory surgical operation was eventually performed, and histological examination of the surgical specimen revealed leprous peripheral neuropathy of the peroneal nerve. The patient...

journal_title：Postgraduate medical journal

authors： Choe W

更新日期：1994-02-01 00:00:00

abstract：:Coronary heart disease, especially when it affects younger individuals, tends to cluster in families. Known risk factors occur in 50-75% of patients with myocardial infarction. Yet commonly occurring risk factors are not strongly inherited, and the familial aggregation of coronary heart diseas may not be attributable ...

journal_title：Postgraduate medical journal

authors： Epstein FH

更新日期：1976-08-01 00:00:00

abstract：:The body composition of the 17 members of the BMRES was studied using body weight and fat fold calipers, with measurements of whole body potassium and nitrogen. The full assessment was made just before departure from Birmingham and immediately on return. Daily observations of body weight and fat folds were made during...

journal_title：Postgraduate medical journal

authors： Harvey TC,James HM,Chettle DR

更新日期：1979-07-01 00:00:00

abstract：:A 19-year-old girl developed generalised anhidrosis following typhoid fever. Elaborate investigations disclosed nothing abnormal. A skin biopsy revealed the presence of atrophic as well as normal eccrine glands. This appears to be the third case of its kind in the English literature. It is postulated that typhoid feve...

journal_title：Postgraduate medical journal

authors： Raveenthiran V

更新日期：1995-07-01 00:00:00

abstract：:The occurrence of ketoacidosis in out-patient diabetics treated with continuous subcutaneous insulin infusion (CSII) has received little attention. We report two such cases of ketosis, each precipitated by infection and occurring in patients previously well controlled on CSII. This report illustrates that the risk of ...

journal_title：Postgraduate medical journal

authors： Boulton AJ,Knight G,Drury J,Ward JD

更新日期：1983-07-01 00:00:00

abstract：:A patient is described who presented with the classical symptomatology and profound electrolyte disturbance of the Verner-Morrison syndrome due to a pancreatic apudoma secreting vasoactive intestinal polypeptide (VIP). Diagnosis was confirmed by plasma VIP as measured by a radio-immunoassay technique now available. It...

journal_title：Postgraduate medical journal

authors： Devine BL,Carmichael HA,Russell RI,Joffe SN

更新日期：1978-08-01 00:00:00

abstract：:Altogether 42 million people worldwide have been infected with HIV, and 12 million have died over the last 20 years. Effective antiretroviral therapy has lead to sustained HIV viral suppression and immunological recovery in patients who have been infected with the virus. The incidence of AIDS has declined in the Weste...

journal_title：Postgraduate medical journal

authors： Thaker HK,Snow MH

更新日期：2003-01-01 00:00:00

abstract：:A patient presented with fever, malaise and a staphylococcal wound infection occurring 3 weeks after severe haemorrhage from a lacerated brachial artery. There were no clinical features to suggest Addison's disease but abdominal computed tomography to exclude abdominal sepsis showed bilateral adrenal gland enlargement...

journal_title：Postgraduate medical journal

authors： Wheatley T,Gallagher S,Dixon AK

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:Obesity in mid-life may increase the risk of subsequent dementia. Our objective was to study this risk, focusing on differences by age at the time of recording of obesity, in a large defined population. METHODS:A record linkage cohort study was undertaken using national administrative statistical data on hos...

journal_title：Postgraduate medical journal

authors： Wotton CJ,Goldacre MJ

更新日期：2014-10-01 00:00:00

abstract：:By 30 June 1984, only 99 confirmed and probable cases of toxic shock syndrome (TSS) had been reported in the British Isles. Sixty-three were related to menstruation in women aged 14 to 54 years who used tampons of various brands and absorbencies; 33 (52%) of these cases were in girls under 20. Five women died (8%) and...

journal_title：Postgraduate medical journal

authors： de Saxe MJ,Hawtin P,Wieneke AA

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To examine the current attitudes towards the prevention of venous thromboembolism among a cohort of surgeons. DESIGN:A postal survey, comprising a questionnaire covering various aspects of venous thromboembolism prophylaxis was sent to all (n=84) consultant general surgeons in Wales. RESULTS:Replies were re...

journal_title：Postgraduate medical journal

authors： Williams EV,Williams RS,Hughes JL,Williams KL,Foster ME,Lewis MH

更新日期：2002-02-01 00:00:00

abstract：:Chlorpromazine-induced agranulocytosis is an uncommon disorder associated with a high frequency of fatality. We describe two patients with chlorpromazine-induced granulocytosis in whom granulocyte colony stimulating factor (G-CSF) administration enhanced the speed of neutrophil recovery. No toxicity was noted with G-C...

journal_title：Postgraduate medical journal

authors： Kendra JR,Rugman FP,Flaherty TA,Myers A,Horsfield N,Barton A,Russell L

更新日期：1993-11-01 00:00:00

abstract：:Six Arabs subjects (three postpubertal, two prepubertal and one pubertal) from three interrelated Omani families with male pseudohermaphroditism due to 5 alpha-reductase-2 deficiency were evaluated. These subjects had been raised as girls since birth as they were born with a clitoral-like phallus and ambiguous externa...

journal_title：Postgraduate medical journal

authors： al-Attia HM

更新日期：1997-12-01 00:00:00

abstract：:We report a case of severe chronic iron deficiency anaemia secondary to blood loss from gastric angiodysplasia. The clinical features, diagnosis and management of this uncommon condition are discussed. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Millar AB

更新日期：1987-10-01 00:00:00

abstract：:Spironolactone therapy is a well-known cause of hyperkalaemia, but in susceptible patient, it may also be associated with metabolic acidosis. We report a case of severe renal tubular acidosis (Type IV) with life-threatening hyperkalaemia caused by spironolactone, and discuss the mechanisms by which this may occur. ...

journal_title：Postgraduate medical journal

authors： O'Connell JE,Colledge NR

更新日期：1993-11-01 00:00:00

abstract：:Epilepsy is common and serious (prevalence 750 per 100 000) and has an impact upon employment, education, and driving. The diagnosis requires a detailed history including witness account. Clinicians must distinguish seizures particularly from syncope and psychogenic attacks. Electroencephalography and magnetic resonan...

journal_title：Postgraduate medical journal

authors： Hadjikoutis S,Smith PE

更新日期：2005-07-01 00:00:00