A model for rational introduction of new and expensive medicines.

abstract：:Patient preference for intravenous or subcutaneous heparin in the treatment of deep venous thrombosis was assessed in a randomized cross-over study. Twenty patients with venographically proven deep venous thrombosis were randomized to receive subcutaneous or intravenous heparin for 3 days followed by 3 days of the oth...

journal_title：Postgraduate medical journal

authors： Robinson AM,McLean KA,Greaves M,Channer KS

更新日期：1993-02-01 00:00:00

abstract：:A case of Peutz-Jeghers syndrome with polyps in the gall bladder is presented. No previous description of this finding has been reported. The literature regarding known sites of polyposis in this condition is reviewed. ...

journal_title：Postgraduate medical journal

authors： Foster DR,Foster DB

更新日期：1980-05-01 00:00:00

abstract：:Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical ...

journal_title：Postgraduate medical journal

authors： Mahy IR,Jennings KP

更新日期：1998-06-01 00:00:00

abstract：:The body composition of the 17 members of the BMRES was studied using body weight and fat fold calipers, with measurements of whole body potassium and nitrogen. The full assessment was made just before departure from Birmingham and immediately on return. Daily observations of body weight and fat folds were made during...

journal_title：Postgraduate medical journal

authors： Harvey TC,James HM,Chettle DR

更新日期：1979-07-01 00:00:00

abstract：:A patient with acute lymphoblastic leukaemia who developed ovarian and uterine leukaemic relapse while in bone marrow remission is described. Pelvic relapse is rarely reported during the clinical course of leukaemia in females. Pelvic ultrasonography, a non-invasive procedure, was of value as an aid in detecting pelvi...

journal_title：Postgraduate medical journal

authors： Cantwell B,Cantwell D,Fennelly JJ

更新日期：1982-11-01 00:00:00

abstract：:A 65 year old man was admitted with segmental consolidation of the left upper lobe after having stayed in a hotel for 2 days. He deteriorated rapidly on conventional antibiotic therapy and required ventilatory support. Acinetobacter calcoaceticus var. anitratus was grown from the sputum and blood cultures, which was t...

journal_title：Postgraduate medical journal

authors： Achar KN,Johny M,Achar MN,Menon NK

更新日期：1993-12-01 00:00:00

abstract：:Ganglioneuroblastoma in the spinal region is rare, the treatment of choice being surgical excision. We present a 21 year old male who was diagnosed to have this condition in the dorsolumbar spinal region. The tumour was extending intraspinally and was unresectable. Combination chemotherapy with Adriamycin (doxorubicin...

journal_title：Postgraduate medical journal

authors： Raina V,Kamble R,Tanwar R,Singh SP,Sharma S

更新日期：1993-09-01 00:00:00

abstract：:Four hundred and fifty asymptomatic general practice patients and 330 hospital inpatients had their stools tested for occult blood with the Haemoccult and Fecatwin methods. In general practice, 9/64 (14%) of patients with a positive result had a colonic neoplasm (three carcinomas, one Dukes' Stage A, two Dukes' Stage ...

journal_title：Postgraduate medical journal

authors： Barrison IG,Parkins RA

更新日期：1985-08-01 00:00:00

abstract：:Infants of HBsAg-positive mothers (Group I) as well as those born to women without HBV markers (Group II) were vaccinated with a 10 micrograms dose of a recombinant DNA hepatitis B vaccine within 24 hours after birth according to a 0, 1, and 2 month schedule, with a booster dose planned 12 months later. Vaccination re...

journal_title：Postgraduate medical journal

authors： Meheus A,Alisjahbana A,Vranckx R,Sukadi A,Usman A,Ngantung W,Sugita E,Safary A,André F,Reniers J

更新日期：1987-01-01 00:00:00

abstract：:Cystinuria is an autosomal recessive disorder in renal tubular and intestinal transport of dibasic amino acids, which results in increased urinary excretion of cystine, ornithine, lysine and arginine. It affects 1 in 20 000 people and is caused by a defect in the rBAT gene on chromosome 2. Development of urinary tract...

journal_title：Postgraduate medical journal

authors： Ahmed K,Dasgupta P,Khan MS

更新日期：2006-12-01 00:00:00

abstract：:Six cases of tuberculous meningitis, all occurring in patients over the age of 65, are described. All patients presented with an acute illness, primarily with a confusional state. Headache was a symptom in only two patients and the cases were not confined to ethnic minority groups. The mortality was 50%. ...

journal_title：Postgraduate medical journal

authors： Dixon PE,Hoey C,Cayley AC

更新日期：1984-09-01 00:00:00

abstract：:Video evaluation of resuscitation is becoming increasingly integrated into practice in a number of clinical settings. The purpose of this review article is to examine how video may enhance clinical care during resuscitation. As healthcare and available therapeutic interventions evolve, re-evaluation of accepted paradi...

journal_title：Postgraduate medical journal

authors： Lowe DJ,Dewar A,Lloyd A,Edgar S,Clegg GR

更新日期：2017-08-01 00:00:00

abstract：:Alcohol is a major cause of liver cirrhosis in the Western world and accounts for the majority of cases of liver cirrhosis seen in district general hospitals in the UK. The three most widely recognised forms of alcoholic liver disease are alcoholic fatty liver (steatosis), acute alcoholic hepatitis, and alcoholic cirr...

journal_title：Postgraduate medical journal

authors： Walsh K,Alexander G

更新日期：2000-05-01 00:00:00

abstract：:The effect of cold in the manifestations of coronary heart disease is reviewed. The mechanisms involved which may include increased peripheral resistance and increased coronary vascular resistance are unclear. ...

journal_title：Postgraduate medical journal

authors： Hall RJ,Bullock RE,Albers C

更新日期：1983-01-01 00:00:00

abstract：:This review presents our experience in the use of propranolol in the management of cardiac infarction. The drug has now been shown to have a definite place, not only in the prevention of cardiac infarction, but also in the treatment of some of the complications. The drug has also been advocated because it may minimiz...

journal_title：Postgraduate medical journal

authors： Sloman G,Hunt D,Ross D

更新日期：1976-01-01 00:00:00

abstract：:Cardiovascular complications of cirrhosis include cardiac dysfunction and abnormalities in the central, splanchnic and peripheral circulation, and haemodynamic changes caused by humoral and nervous dysregulation. Cirrhotic cardiomyopathy implies systolic and diastolic dysfunction and electrophysiological abnormalities...

journal_title：Postgraduate medical journal

authors： Møller S,Henriksen JH

更新日期：2009-01-01 00:00:00

abstract：:The aortic root links the left ventricle and ascending aorta and functions as a support structure for the aortic valve. It can be affected by a variety of congenital and acquired conditions, some of which are potentially life threatening. Echocardiography and cardiac magnetic resonance imaging are established non-inva...

journal_title：Postgraduate medical journal

authors： Vargas HA,Hoey ET,Gopalan D,Agrawal SK,Screaton NJ,Gulati GS

更新日期：2009-07-01 00:00:00

abstract：:Gastric cancer is a cause of significant morbidity and mortality. There are several risk factors, with occupation emerging as one of these. There is considerable evidence that occupations in coal and tin mining, metal processing, particularly steel and iron, and rubber manufacturing industries lead to an increased ris...

journal_title：Postgraduate medical journal

authors： Raj A,Mayberry JF,Podas T

更新日期：2003-05-01 00:00:00

abstract：:There has been a dramatic change in the way that resuscitation decisions are made for older hospital inpatients in the UK. In less than 20 years many geriatric medicine wards have moved from an "opt-in" policy (where the default position is not to provide resuscitation) to a position where resuscitation is widely avai...

journal_title：Postgraduate medical journal

authors： Bowker L

更新日期：2009-11-01 00:00:00

abstract：:Overdosage with cardiac glycosides is well documented, but not usually fatal. A case is described in which cardiac arrest in asystole was associated with a serum digoxin level of 50-4 microgram/1, the highest concentration yet reported after oral administration. ...

journal_title：Postgraduate medical journal

authors： Nicholls DP

更新日期：1977-05-01 00:00:00

abstract：:Thirty-four varicella-zoster virus (VZV) seronegative nurses were vaccinated with the live varicella vaccine (Varilrix) and followed for periods of up to 36 months. No major vaccine reactions were observed. At 5 and 12 months, 94% of the nurses had seroconverted but at 3 years, only 64% retained antibody activity. How...

journal_title：Postgraduate medical journal

authors： Ndumbe PM,Cradock-Watson JE,Heath RB,Levinsky RJ

更新日期：1985-01-01 00:00:00

abstract：:We studied two sisters who developed large non-toxic goitres in adolescence. Deiodinase deficiency was diagnosed by a rapid thyroid uptake of radioactive iodine (RAI) at 2 hours associated with a marked fall in thyroidal 131I by 24 hours. Serial RAI scans in the second patient documented evolution of the iodine-defici...

journal_title：Postgraduate medical journal

authors： Hirsch HJ,Shilo S,Spitz IM

更新日期：1986-06-01 00:00:00

abstract：:Four studies have been carried out on propofol in this department, one being part of a multicentre trial. The minimum induction dose in unpremedicated patients was found to be 2.5 mg/kg. Propofol has been shown to be an acceptable induction agent, although with an incidence of pain on injection which is much higher wh...

journal_title：Postgraduate medical journal

authors： Grounds RM,Morgan M,Lumley J

更新日期：1985-01-01 00:00:00

abstract：:Motor neurone disease (MND), or amyotrophic lateral sclerosis (ALS), is a neurodegenerative disorder of unknown aetiology. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Confirming the diagnosis may initially be difficult until the full clinical features ar...

journal_title：Postgraduate medical journal

authors： Talbot K

更新日期：2002-09-01 00:00:00

abstract：:Tienilic acid is a diuretic-uricosuric compound whose natriuretic site of action is in the cortical diluting segment of the distal nephron. Oral doses of 250 mg given to normal human volunteers provided peak blood levels of 10--11 micrograms/ml at 3--4 hours after administration. Approximately 40% of the dose was reco...

journal_title：Postgraduate medical journal

authors： Dubb JW,Stote RM,Maass AR,Hwang BV,Familiar RG,Alexander F

更新日期：1979-01-01 00:00:00

abstract：:Herpes simplex encephalitis may be underdiagnosed in Britain. We report eight patients treated at one hospital over three years. Fever, impaired consciousness or focal neurological signs were seen in all patients at presentation but herpes simplex encephalitis was rarely considered as the initial diagnosis. The electr...

journal_title：Postgraduate medical journal

authors： Gulliford MC,Chandrasekera CP,Cooper RA,Murphy RP

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVE:Lactate dehydrogenase (LDH) anomaly is one of the macroenzymes. Macroenzymes are enzymes in serum that have formed high molecular mass complexes, either by self polymerisation or by association with other serum components. The aim of this study was to identify the properties of LDH anomaly and observe the cha...

journal_title：Postgraduate medical journal

authors： Liu ZJ,Zhang Y,Zhang XB,Yang X

更新日期：2004-08-01 00:00:00

abstract：:Peripheral lymphadenopathy is rarely observed, whereas mesenteric lymphadenopathy is found occasionally on laparotomies in patients with familial Mediterranean fever (FMF). Retroperitoneal lymphadenopathy was reported only once in an autopsy of a patient with FMF. Our case is the second one, and the first one to be di...

journal_title：Postgraduate medical journal

authors： Rimon D,Meir Y,Cohen L

更新日期：1989-10-01 00:00:00

abstract：:A 28 year old female patient with Cushing's syndrome due to an adrenal adenoma also suffered from recurrent urinary infections (proteus), tonsillitis (streptococcus), permanent candidiasis and perimandibular abscess (Staphylococcus pyogenes). Suppression of cellular and humoral immunity was confirmed by in vitro tests...

journal_title：Postgraduate medical journal

authors： Würzburger MI,Prelević GM,Brkić SD,Vucković S,Pendić B

更新日期：1986-07-01 00:00:00

abstract：:Essential tremor is the most common cause of tremor involving upper limbs, head and voice. The first line of treatment for limb tremor is pharmacotherapy with propranolol or primidone. However, these two drugs reduce the tremor severity by only half. In medication refractory and functionally disabling tremor, alternat...

journal_title：Postgraduate medical journal

authors： Sharma S,Pandey S

更新日期：2020-02-01 00:00:00