Ischaemic colitis associated with psychotropic drugs.

abstract：:A case of severe hypercalcaemia associated with a non-secretory multiple myeloma in the absence of skeletal deposits is described. The importance of considering this condition in the differential diagnosis of hypercalcaemia in the elderly is discussed. ...

journal_title：Postgraduate medical journal

authors： Chew D,Playfer JR

更新日期：1988-06-01 00:00:00

abstract：:A doubld-blind crossover study of oral domperidone (10 mg t.d.s.) involving 48 patients suffering from chronic postprandial dyspepsia, showed a significant relief of symptoms on active treatment compared to placebo. The trial lasted eight weeks, the crossover in medication taking place at four weeks. Side effects were...

journal_title：Postgraduate medical journal

authors： Englert W,Schlich D

更新日期：1979-01-01 00:00:00

abstract：:Excess body weight, as defined by the body mass index (BMI), has been associated with several diseases and includes subjects who are overweight (BMI≥25-29.9 kg/m(2)) or obese (BMI≥30 kg/m(2)). Overweight and obesity constitute the fifth leading risk for overall mortality, accounting for at least 2.8 million adult deat...

journal_title：Postgraduate medical journal

authors： Bardou M,Barkun AN,Martel M

更新日期：2013-09-01 00:00:00

abstract：:In order to assess the neurohormonal responses to oral administration of two drugs with different antihypertensive mechanisms, and their implications for long-term efficacy, we studied the changes in plasma renin activity, aldosterone, catecholamines and blood pressure after two cross-over periods of treatment with ca...

journal_title：Postgraduate medical journal

authors： Rabinad E,Gaya J,Rivera F,Ingelmo M,Balcells A

更新日期：1986-01-01 00:00:00

abstract：:We report three cases of a distinctive palmar-plantar erythema associated with the treatment of non-Hodgkin's lymphoma and acute myeloid leukaemia. The rash is characterized by a painful, sharply demarcated, intense erythema of the palms and/or soles followed by bulla formation, desquamation and healing. The eruption ...

journal_title：Postgraduate medical journal

authors： Pagliuca A,Kaczmarski R,Mufti GJ

更新日期：1990-03-01 00:00:00

abstract：:A patient with alcoholic cardiomyopathy is described in whom cardiovascular function capacity and radiological heart size fluctuated widely with periods of heavy drinking and abstinence. On two occasions, cessation of drinking resulted in clinical recovery from severe degrees of congestive failure and in complete reve...

journal_title：Postgraduate medical journal

authors： Kupari M

更新日期：1984-02-01 00:00:00

abstract：:Cystinuria is an autosomal recessive disorder in renal tubular and intestinal transport of dibasic amino acids, which results in increased urinary excretion of cystine, ornithine, lysine and arginine. It affects 1 in 20 000 people and is caused by a defect in the rBAT gene on chromosome 2. Development of urinary tract...

journal_title：Postgraduate medical journal

authors： Ahmed K,Dasgupta P,Khan MS

更新日期：2006-12-01 00:00:00

abstract：:We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement. Some dangers of this therapy and necessary precautions ...

journal_title：Postgraduate medical journal

authors： Burns A,Brown TM,Semple P

更新日期：1983-08-01 00:00:00

abstract：:Two young patients with sickle cell trait (AS haemaglobinopathy) and ischaemic stroke are reported. The stroke involved the internal carotid artery territory in one and the brainstem in the other. A review of the literature is presented to suggest that the association of sickle cell trait and cerebral infarction is mo...

journal_title：Postgraduate medical journal

authors： Radhakrishnan K,Thacker AK,Maloo JC,el-Mangoush MA

更新日期：1990-12-01 00:00:00

abstract：:Intraperitoneal free gas seen radiologically as air under the diaphragm nearly always indicates a perforated abdominal viscus that requires surgical intervention. Rarely, however, the presence of a pneumoperitoneum may not indicate an intra-abdominal perforation and thus may not require laparotomy. Such a situation is...

journal_title：Postgraduate medical journal

authors： Williams NM,Watkin DF

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:There are wide variations in survival after cardiopulmonary resuscitation. The aim of this survey was to describe how equipment provision of resuscitation trolleys was deployed in a range of clinical ward areas. METHODS:The equipment in randomly selected resuscitation trolleys in all 14 South West Thames Re...

journal_title：Postgraduate medical journal

authors： Hogh L,Kane I,Bhalla A,Ward MC

更新日期：2005-06-01 00:00:00

abstract：:Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies...

journal_title：Postgraduate medical journal

authors： McAlister FA,Teo KK

更新日期：1997-04-01 00:00:00

abstract：:A series of 8 adult patients with stable bronchial asthma and an established diagnois of essential hypertension (WHO I and II) was studied in a randomized double-blind cross-over study to assess the effect of captopril (50-100 mg/day) and verapamil (160-240 mg/day) on blood pressure, lung function and asthmatic sympto...

journal_title：Postgraduate medical journal

authors： Riska H,Stenius-Aaniala B,Sovijärvi AR

更新日期：1986-01-01 00:00:00

abstract：:Essential tremor is the most common cause of tremor involving upper limbs, head and voice. The first line of treatment for limb tremor is pharmacotherapy with propranolol or primidone. However, these two drugs reduce the tremor severity by only half. In medication refractory and functionally disabling tremor, alternat...

journal_title：Postgraduate medical journal

authors： Sharma S,Pandey S

更新日期：2020-02-01 00:00:00

abstract：:The effect of digoxin (0.25 mg t.d.s.) given orally for 5 days, on sodium excretion, plasma renin activity, plasma aldosterone and blood pressure has been studied in 6 normotensive subjects, on a constant sodium intake. Average serum digoxin level measured in 5 subjects on the 5th day of treatment was in the upper ran...

journal_title：Postgraduate medical journal

authors： Cappuccio FP,Markandu ND,Sagnella GA,MacGregor GA

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:Previous research has shown that sicker patients are less satisfied with their healthcare, but specific effects of adverse health outcomes have not been investigated. The present study aimed to assess whether patients who experience adverse outcomes, in hospital or after discharge, differ in their evaluation...

journal_title：Postgraduate medical journal

authors： Marang-van de Mheen PJ,van Duijn-Bakker N,Kievit J

更新日期：2008-02-01 00:00:00

abstract：:A study was undertaken to determine the effects of long-term insulin therapy on the development and regression of lipid perturbations and experimental cholesterol atherosclerosis in rabbits: (1) Insulin administration for 15 days significantly reduced plasma lipid levels and free fatty acids in rabbits fed a high-chol...

journal_title：Postgraduate medical journal

authors： Marquié G

更新日期：1978-02-01 00:00:00

abstract：:Prostatic involvement is an unusual complication of Wegener's granulomatosis. We report two cases with this complication and emphasize the importance of recognizing this manifestation in diagnosis and management of the disease condition. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Woolf A,Falzon M

更新日期：1987-01-01 00:00:00

abstract：:The presenting features of 250 consecutive patients who underwent a ventilation/perfusion lung scan for suspected pulmonary embolus (PE) were analysed. Ninety-six patients had lung scans highly suggestive of PE, with one or more unmatched segmental perfusion defects (scan positive), 86 had low probability scans (scan ...

journal_title：Postgraduate medical journal

authors： Fennerty AG,Shetty HG,Paton D,Roberts G,Routledge PA,Campbell IA

更新日期：1990-04-01 00:00:00

abstract：:Amlodipine is a dihydropyridine calcium antagonist with a unique pharmacokinetic profile providing advantages over other therapies of its kind. It has been shown to possess high oral absorption, long elimination half-life, smooth onset of action and long duration of pharmacodynamic activity. These properties result in...

journal_title：Postgraduate medical journal

authors： Taylor SH

更新日期：1991-01-01 00:00:00

abstract：:This review of the treatment of airways obstruction attempts to demonstrate that treatment needs to be guided by an understanding of pathophysiology and pathogenesis as well as a knowledge of the natural history of the diseases underlying airways obstruction and their causes. This enables effective health education an...

journal_title：Postgraduate medical journal

authors： Clark TJ

更新日期：1983-01-01 00:00:00

abstract：PURPOSE OF STUDY:The aim of the study is to describe the prevalence of illicit drug use in England and Wales using data from the UK Survey of Non-Medical Use of Prescription Drugs (NMURx) programme and to compare against the well-established Crime Survey England and Wales (CSEW). The rationale is that recreational and ...

journal_title：Postgraduate medical journal

authors： Ng FL,Rockhill K,Black J,May KP,Whittington MD,Wood DM,Dargan PI,Green JL

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Epidemiological and family studies suggest that lung cancer results from the combined effects of age, smoking and genetic factors. Chronic obstructive pulmonary disease (COPD) is also an independent risk factor for lung cancer and coexists in 40-60% of lung cancer cases. METHODS:In a two-stage case-control ...

journal_title：Postgraduate medical journal

authors： Young RP,Hopkins RJ,Hay BA,Epton MJ,Mills GD,Black PN,Gardner HD,Sullivan R,Gamble GD

更新日期：2009-10-01 00:00:00

abstract：:A 5 year old female child presented with a psoas haematoma as the first manifestation of haemophilia B. Molecular genetic studies were performed to investigate the inheritance of the disorder and the mechanisms by which females may express the haemophilia B phenotype are discussed. ...

journal_title：Postgraduate medical journal

authors： Palmer S,Standen GR,Yates P,Oakhill A

更新日期：1994-11-01 00:00:00

abstract：:Functional metastatic adrenocortical carcinoma is an uncommon cause of Cushing's syndrome, which rarely responds to conventional treatment. A patient presenting with Cushing's syndrome secondary to adrenocortical carcinoma underwent surgical resection. Postoperatively, she developed metastatic disease resistant to con...

journal_title：Postgraduate medical journal

authors： Chan NN,Isaacs AJ

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The survival of whites who have been treated for pernicious anaemia (PA) is unaffected, apart from incurring a greater risk of gastric cancers. The long term outcome of PA in Chinese is unknown. METHODS:A hospital based prospective longitudinal study of Chinese PA patients was conducted. Patients with known...

journal_title：Postgraduate medical journal

authors： Chan JC,Liu HS,Kho BC,Lau TK,Li VL,Chan FH,Leong IS,Pang HK,Lee CK,Liang YS

更新日期：2008-12-01 00:00:00

abstract：:Coronary heart disease, especially when it affects younger individuals, tends to cluster in families. Known risk factors occur in 50-75% of patients with myocardial infarction. Yet commonly occurring risk factors are not strongly inherited, and the familial aggregation of coronary heart diseas may not be attributable ...

journal_title：Postgraduate medical journal

authors： Epstein FH

更新日期：1976-08-01 00:00:00

abstract：:Leg ulcer is a leading cause of morbidity among older subjects, especially women in the Western world. About 400 years BC, Hippocrates wrote, "In case of an ulcer, it is not expedient to stand, especially if the ulcer be situated on the leg". Hippocrates himself had a leg ulcer. The best treatment of any leg ulcer dep...

journal_title：Postgraduate medical journal

authors： Sarkar PK,Ballantyne S

更新日期：2000-11-01 00:00:00

abstract：:Acute ventilatory failure is a challenging yet increasingly common medical emergency reflecting the growing burden of respiratory disease. It is not a diagnosis in itself but the end result of a diversity of disease processes culminating in arterial hypoxaemia and hypercapnia. This review focuses on key management iss...

journal_title：Postgraduate medical journal

authors： Chakrabarti B,Calverley PM

更新日期：2006-07-01 00:00:00

abstract：:Programmed cell death (PCD) is an important terminal pathway for cells of multicellular organisms, and is involved in a variety of biological events that include morphogenesis, maintenance of tissue homeostasis, and elimination of harmful cells. Dysfunction of PCD leads to various diseases in humans, especially variou...

journal_title：Postgraduate medical journal

authors： Sun Y,Peng ZL

更新日期：2009-03-01 00:00:00