Genetic analysis in a female manifesting haemophilia B.

abstract：:A patient presented with retroperitoneal fibrosis but without any ureteric obstruction. The diagnosis was made by an abdominal CT scan and also at laparotomy. Post-operatively, she developed hypertensive encephalopathy. An isotope renogram with captopril was abnormal but not diagnostic of renal artery stenosis. The pa...

journal_title：Postgraduate medical journal

authors： Das D,Brigg J,Brown CM

更新日期：1999-12-01 00:00:00

abstract：PURPOSE:Workplace-based assessments (WBAs) were originally intended to inform learning and development by structuring effective observation-based feedback. The success of this innovation has not yet been established due in part to the widely varied tools, implementation strategies and research approaches. Using a conce...

journal_title：Postgraduate medical journal

authors： Barrett A,Galvin R,Scherpbier AJ,Teunissen PW,O'Shaughnessy A,Horgan M

更新日期：2017-03-01 00:00:00

abstract：:Cystinuria is an autosomal recessive disorder in renal tubular and intestinal transport of dibasic amino acids, which results in increased urinary excretion of cystine, ornithine, lysine and arginine. It affects 1 in 20 000 people and is caused by a defect in the rBAT gene on chromosome 2. Development of urinary tract...

journal_title：Postgraduate medical journal

authors： Ahmed K,Dasgupta P,Khan MS

更新日期：2006-12-01 00:00:00

abstract：:Micronutrients play a central part in metabolism and in the maintenance of tissue function. An adequate intake therefore is necessary, but provision of excess supplements to people who do not need them may be harmful. Single micronutrient deficiency states are comparatively easily recognised and treated. Subclinical d...

journal_title：Postgraduate medical journal

authors： Shenkin A

更新日期：2006-09-01 00:00:00

abstract：:Submucosal dissection of the oesophagus is a rare oesophageal disorder. We report a patient who had recurrent episodes of dissection and achalasia. Both recurrence and the association with achalasia are to our knowledge unique. ...

journal_title：Postgraduate medical journal

authors： Hooper TL,Gholkar J,Smith SR,Manns JJ,Moussalli H

更新日期：1986-10-01 00:00:00

abstract：:Some antifungal agents have been tested qualitatively in various associations against species of Candida, Cryptococcus and Torulopsis. The method used was the channel test and the results are confirmed by comparison with the serial dilution test in agar. The antagonism in vitro with the combination of amphotericin B i...

journal_title：Postgraduate medical journal

authors： Dupont B,Drouhet E

更新日期：1979-09-01 00:00:00

abstract：:Peyronie's disease can cause severe physical and psychological distress. Of 31 cases in this retrospective study, 12 underwent spontaneous improvement in their symptoms which makes the assessment of active treatment in other patients difficult. The indications and limitations of operative approach are discussed. ...

journal_title：Postgraduate medical journal

authors： Odiase VO,Whitaker RH

更新日期：1980-11-01 00:00:00

abstract：:Episodic muscular weakness, commonly associated with alterations of serum potassium, is the cardinal feature of periodic paralysis. The combination of transient hyperkalaemia and rigors occurring during febrile episodes of malaria is suggested as the underlying cause which precipitated the muscular paralysis. Three pa...

journal_title：Postgraduate medical journal

authors： Senanayake N,Wimalawansa SJ

更新日期：1981-05-01 00:00:00

abstract：:A case of hypereosinophilic syndrome is reported. Investigation failed to reveal any precipitating cause or evidence of leukaemia. Death was due to intractable cardiac failure, and post-mortem examination showed infiltration of the myocardium with sheets of immature cells. The relevance of these cells is discussed and...

journal_title：Postgraduate medical journal

authors： Scott DG,Leatherdale BA

更新日期：1979-01-01 00:00:00

abstract：:Essential tremor is the most common cause of tremor involving upper limbs, head and voice. The first line of treatment for limb tremor is pharmacotherapy with propranolol or primidone. However, these two drugs reduce the tremor severity by only half. In medication refractory and functionally disabling tremor, alternat...

journal_title：Postgraduate medical journal

authors： Sharma S,Pandey S

更新日期：2020-02-01 00:00:00

abstract：:As a tertiary referral centre of spinal surgery, the Royal National Orthopaedic Hospital (RNOH) handles hundreds of spinal cases a year, often with complex pathology and complex care needs. Despite this, issues were raised at the RNOH following lack of sufficient documentation of preoperative and postoperative clinica...

journal_title：Postgraduate medical journal

authors： Pace V,Farooqi O,Kennedy J,Park C,Cowan J

更新日期：2018-05-01 00:00:00

abstract：:Fifty two cases of tuberculosis of the breast encountered over a 15 year period and accounting for 3% of all breast lesions are reported. The classic presentation was a breast lump with associated sinus in 39%, isolated breast lump in 23%, sinus without lump in 12%, and tender nodularity in 23% of the patients. Associ...

journal_title：Postgraduate medical journal

authors： Khanna R,Prasanna GV,Gupta P,Kumar M,Khanna S,Khanna AK

更新日期：2002-07-01 00:00:00

abstract：:A patient is described who developed acute peripheral neuropathy of Guillain-Barré type occurring shortly after commencement of captopril for moderately severe hypertension and resolving after discontinuation of the drug. ...

journal_title：Postgraduate medical journal

authors： Chakraborty TK,Ruddell WS

更新日期：1987-03-01 00:00:00

abstract：:A woman aged 35 years from the Philippines presented with epigastric discomfort associated with an epigastric mass. On examination the liver was markedly enlarged. ...

journal_title：Postgraduate medical journal

authors： Kreel L

更新日期：1989-04-01 00:00:00

abstract：:Thirty-one patients with radiolucent common bile duct stones received medical treatment. Nineteen had Rowachol, a terpene preparation, eight (42%) achieving complete stone disappearance within 3 to 48 months. Fifteen (including 3 of the above) took Rowachol with bile acid (chenodeoxycholic in 11, ursodeoxycholic in 4)...

journal_title：Postgraduate medical journal

authors： Somerville KW,Ellis WR,Whitten BH,Balfour TW,Bell GD

更新日期：1985-04-01 00:00:00

abstract：:Warfarin, a vitamin K antagonist, is the most widely used oral anticoagulant in the world. It is cheap and effective, but its use is limited in many patients by unpredictable levels of anticoagulation, which increases the risk of thromboembolic or haemorrhagic complications. It also requires regular blood monitoring a...

journal_title：Postgraduate medical journal

authors： Saraf K,Morris PD,Garg P,Sheridan P,Storey R

更新日期：2014-09-01 00:00:00

abstract：:Two patients with nephrotic syndrome developed fatal fulminant hepatitis B following withdrawal of prednisolone or cyclophosphamide. Immunosuppressive therapy probably enhanced hepatitis B virus (HBV) replication and widespread infection of hepatocytes; its withdrawal permitted a return of immune competence resulting ...

journal_title：Postgraduate medical journal

authors： Onwubalili JK

更新日期：1988-04-01 00:00:00

abstract：:We studied two sisters who developed large non-toxic goitres in adolescence. Deiodinase deficiency was diagnosed by a rapid thyroid uptake of radioactive iodine (RAI) at 2 hours associated with a marked fall in thyroidal 131I by 24 hours. Serial RAI scans in the second patient documented evolution of the iodine-defici...

journal_title：Postgraduate medical journal

authors： Hirsch HJ,Shilo S,Spitz IM

更新日期：1986-06-01 00:00:00

abstract：:Percutaneous endoscopic gastrostomy (PEG) was performed on 28 elderly patients (mean age 82 years) who were dysphagic and intolerant of naso-gastric feeding. Twenty-six patients were recovering from a stroke; the interval between the onset of stroke and PEG averaged 63 days. The procedure was successful and well toler...

journal_title：Postgraduate medical journal

authors： Finucane P,Aslan SM,Duncan D

更新日期：1991-04-01 00:00:00

abstract：:Multiple lymphomatous polyposis is an uncommon but distinctive form of gastrointestinal lymphoma. Clinical symptoms may closely resemble those of colorectal carcinoma and diagnostic confusion may result. The condition has a characteristic pathological appearance and immunophenotype which is important in allowing disti...

journal_title：Postgraduate medical journal

authors： Carder PJ,Gouldesbrough DR

更新日期：1993-05-01 00:00:00

abstract：:Although the relationship between group A streptococcal upper respiratory tract infection and the development of acute rheumatic fever has been known for many years, the pathogenetic mechanism(s) have never been defined. Thus, the mechanism of damage to the valves and to the myocardium in patients with rheumatic fever...

journal_title：Postgraduate medical journal

authors： Kaplan EL

更新日期：1992-01-01 00:00:00

abstract：:High flow arteriogenic priapism is uncommon and usually occurs after trauma to the genitoperineal area. The onset of prolonged erection can be delayed and is often relatively pain free. Arteriography in this case illustrated the causative bilateral arteriocavernosal fistulae and pseudoaneurysms. Treatment consisted of...

journal_title：Postgraduate medical journal

authors： Gujral S,MacDonagh RP,Cavanagh PM

更新日期：2001-03-01 00:00:00

abstract：:Four hundred and fifty asymptomatic general practice patients and 330 hospital inpatients had their stools tested for occult blood with the Haemoccult and Fecatwin methods. In general practice, 9/64 (14%) of patients with a positive result had a colonic neoplasm (three carcinomas, one Dukes' Stage A, two Dukes' Stage ...

journal_title：Postgraduate medical journal

authors： Barrison IG,Parkins RA

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the reasons why primary care doctors undertake postgraduate diploma studies in a mixed private/public Asian setting. METHODS:Twenty four past or current postgraduate diploma students of the family medicine unit (FMU) of the University of Hong Kong participated in three fo...

journal_title：Postgraduate medical journal

authors： Lam TP,Lam KF,Tse EY

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:Although risk assessment is an integral part of management, there are currently no risk calculators of long-term mortality after acute coronary syndrome (ACS). The aim was to provide risk equations for 10-year and 20-year mortality following ACS. METHODS:Patients hospitalised with ACS from December 1990 to ...

journal_title：Postgraduate medical journal

authors： Magri CJ,Debono R,Calleja N,Galea J,Fava S

更新日期：2017-05-01 00:00:00

abstract：:Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies...

journal_title：Postgraduate medical journal

authors： McAlister FA,Teo KK

更新日期：1997-04-01 00:00:00

abstract：:In order to assess the neurohormonal responses to oral administration of two drugs with different antihypertensive mechanisms, and their implications for long-term efficacy, we studied the changes in plasma renin activity, aldosterone, catecholamines and blood pressure after two cross-over periods of treatment with ca...

journal_title：Postgraduate medical journal

authors： Rabinad E,Gaya J,Rivera F,Ingelmo M,Balcells A

更新日期：1986-01-01 00:00:00

abstract：:We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient...

journal_title：Postgraduate medical journal

authors： Baruch Y,Ben-Arie Y,Kerner H,Lorber M,Best LA,Gershoni-Baruch R

更新日期：1991-04-01 00:00:00

abstract：:A 12-year-old boy presented with typical features of short incubation tetanus. Spastic paraparesis with a mid-thoracic sensory level was present from the time of the initial examination. X-rays of the spine and lumbar myelogram were normal. The paraparesis improved rapidly and within a month the patient was free of ne...

journal_title：Postgraduate medical journal

authors： Bahemuka M

更新日期：1981-07-01 00:00:00

abstract：:The pharmacokinetics of a single oral dose of clomipramine were examined in a group of depressed patients, 8 female and 2 male with a mean age of 51 years (range 21-78). Their mean clomipramine half-life was 36 hours and mean plasma clomipramine clearance 73 litres per hour, with a wide range in each case. These resul...

journal_title：Postgraduate medical journal

authors： Dawling S,Braithwaite RA,McAuley R,Montgomery SA

更新日期：1980-01-01 00:00:00