The management of congestive heart failure.

Abstract:

:Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies are not maximally applied in patients with this condition. An approach to the patient with congestive heart failure is presented, emphasizing the two distinct syndromes of systolic dysfunction and diastolic dysfunction. Treatment recommendations are derived from consideration of the underlying pathophysiology and the evidence from randomised clinical trials.

journal_name

Postgrad Med J

authors

McAlister FA,Teo KK

doi

10.1136/pgmj.73.858.194

subject

Has Abstract

pub_date

1997-04-01 00:00:00

pages

194-200

issue

858

eissn

0032-5473

issn

1469-0756

journal_volume

73

pub_type

杂志文章,评审
  • Muscarinic receptors in lung.

    abstract::Muscarinic receptors are present on several different cells in lung and are predominantly involved in bronchoconstriction and mucus secretion. Muscarinic receptor activation leads to breakdown of phosphoinositides in airway smooth muscle cell membranes, which leads to intracellular calcium release and contraction. Mus...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Barnes PJ

    更新日期:1987-01-01 00:00:00

  • Safety of low dose methotrexate in elderly patients with rheumatoid arthritis.

    abstract::Weekly low dose methotrexate is an established treatment for rheumatoid arthritis, but its use in elderly people has not been adequately examined. The aim of this study was to evaluate its safety in elderly patients with rheumatoid arthritis. A retrospective review of the clinical records of rheumatoid arthritis patie...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pmj.76.902.787

    authors: Hirshberg B,Muszkat M,Schlesinger O,Rubinow A

    更新日期:2000-12-01 00:00:00

  • Endobronchial tuberculosis--is corticosteroid treatment useful? A report of 8 cases and review of the literature.

    abstract::Eight patients with endobronchial tuberculosis diagnosed on bronchoscopy were treated with antituberculosis drugs and a course of prednisone. The progress of the endobronchial lesions was assessed on repeated examinations. The course of the disease was variable and the endobronchial narrowing improved in two patients ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.66.780.822

    authors: Chan HS,Sun A,Hoheisel GB

    更新日期:1990-10-01 00:00:00

  • Why do primary care doctors undertake postgraduate diploma studies in a mixed private/public Asian setting?

    abstract:OBJECTIVE:The aim of this study was to examine the reasons why primary care doctors undertake postgraduate diploma studies in a mixed private/public Asian setting. METHODS:Twenty four past or current postgraduate diploma students of the family medicine unit (FMU) of the University of Hong Kong participated in three fo...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2005.042077

    authors: Lam TP,Lam KF,Tse EY

    更新日期:2006-06-01 00:00:00

  • Micronutrients in health and disease.

    abstract::Micronutrients play a central part in metabolism and in the maintenance of tissue function. An adequate intake therefore is necessary, but provision of excess supplements to people who do not need them may be harmful. Single micronutrient deficiency states are comparatively easily recognised and treated. Subclinical d...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2006.047670

    authors: Shenkin A

    更新日期:2006-09-01 00:00:00

  • Investigation of cereal toxicity in coeliac disease.

    abstract::Coeliac disease is exacerbated by wheat gluten. A review of methods for the purification, identification and quantitation of wheat proteins to investigate coeliac disease is presented. Recent developments including amino acid sequencing and expression of wheat protein peptides in E. coli should permit characterization...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.63.743.767

    authors: Ciclitira PJ,Ellis HJ

    更新日期:1987-09-01 00:00:00

  • Transient atrial fibrillation in hypertensive patients with thiazide induced hypokalaemia.

    abstract::During the previous 34 months, 3 hypertensive patients on long-term thiazide therapy were admitted to the medical department, Mubarak Hospital, Kuwait, with atrial fibrillation (AF) and hypokalaemia. They received potassium chloride by intravenous infusion, followed by oral therapy with reversion to sinus rhythm. Ther...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.734.1125

    authors: Emara MK,Saadet AM

    更新日期:1986-12-01 00:00:00

  • Focused assessment with sonography in trauma (FAST): should its role be reconsidered?

    abstract::Focused assessment with sonography in trauma (FAST) is a limited ultrasound scan performed in the emergency department to assess patients admitted with blunt abdominal trauma (BAT). It is normally undertaken by emergency physicians in order to identify the presence of free fluid, which may represent haemoperitoneum. T...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2008.076711

    authors: Smith J

    更新日期:2010-05-01 00:00:00

  • Audit of the prevalence and investigation of iron deficiency anaemia in patients with heart failure in hospital practice.

    abstract:PURPOSE OF THE STUDY:Iron deficiency anaemia (IDA) is associated with increased morbidity and mortality in heart failure patients. The aim of our audit was to evaluate the current practice in diagnosis and assessment of IDA in patients admitted with heart failure. STUDY DESIGN:We conducted a retrospective audit of pat...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2019-136867

    authors: Simon S,Ioannou A,Deoraj S,Metaxa S,Mandal AKJ,Missouris CG

    更新日期:2020-04-01 00:00:00

  • Significance of idiopathic deep venous thrombosis.

    abstract::The risk of developing an overt malignancy after an isolated deep venous thrombosis (DVT) is poorly documented. We therefore reviewed a series of patients in whom a solitary idiopathic DVT had been proven by venography at least 12 months earlier. No patient had developed a malignancy at follow-up. However, decreased f...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.60.702.275

    authors: O'Connor NT,Cederholm-Williams SA,Fletcher EW,Allington M,Sharp AA

    更新日期:1984-04-01 00:00:00

  • Life-threatening Mycoplasma pneumoniae infection.

    abstract::Pneumonia due to Mycoplasma pneumoniae is common, but it is rarely life-threatening. A case is reported in a previously healthy adult whose illness was severe enough to require treatment with intermittent positive pressure ventilation (IPPV) for 14 days and which resolved after treatment with corticosteroids. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.56.659.675

    authors: McGonigle R,Wagstaff JK

    更新日期:1980-09-01 00:00:00

  • HIV infection and seizures.

    abstract::New-onset seizures are frequent manifestations of central nervous system disorders in patients infected with human immunodeficiency virus (HIV). Seizures are more common in advanced stages of the disease, although they may occur early in the course of illness. In the majority of patients, seizures are of the generalis...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.75.885.387

    authors: Garg RK

    更新日期:1999-07-01 00:00:00

  • Evaluation of vaginal antifungal formulations in vivo.

    abstract::Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.55.647.648

    authors: McRipley RJ,Erhard PJ,Schwind RA,Whitney RR

    更新日期:1979-09-01 00:00:00

  • Hyperosmolar non-ketotic diabetic coma and rhabdomyolysis.

    abstract::Rhabdomyolysis is a rare but potentially fatal complication of hyperosmolar states. We report a case of severe hyperosmolar non-ketotic diabetic coma causing rhabdomyolysis in a young man. Despite very high levels of creatine kinase there was no detectable myoglobinuria. Creatine kinase estimation should be a standard...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.70.819.44

    authors: Trump D,O'Hanlon S,Rinsler M,Sharp P

    更新日期:1994-01-01 00:00:00

  • Painless stress fractures in diabetic neuropathic feet.

    abstract::We describe two patients with diabetes mellitus and associated neuropathy, who presented with painless foot swelling and no history of trauma. X-Rays revealed recent underlying fractures-in one of a metatarsus, and the other of a proximal phalanx. These were assumed to be 'stress' fractures unassociated with pain beca...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.73.858.241

    authors: Gill G,Benbow S,Tesfaye S,Kaczmarczyk E,Kaye L

    更新日期:1997-04-01 00:00:00

  • Medullary carcinoma of the thyroid metastatic to breast.

    abstract::Medullary carcinoma of the thyroid commonly spreads to the lymphatics and later on in the disease process, to distant sites such as lung, liver and bone. Spread to the breast is rare (only two previous reported cases) and presents a major diagnostic dilemma. We report a case of metastatic medullary carcinoma of the th...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.71.842.744

    authors: Kiely N,Williams N,Wilson G,Williams RJ

    更新日期:1995-12-01 00:00:00

  • Diabetes insipidus complicating myelofibrosis.

    abstract::A 68 year old man developed cranial diabetes insipidus 3 years after the diagnosis of myelofibrosis, coincident with a marked increase in nucleated cell count. No mass lesion was demonstrable on computed tomographic or magnetic resonance imaging. It is suggested that hypothalamic damage was caused by local infiltratio...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.65.759.36

    authors: Dornan TL,Gillett G,Jones PA,Jeffcoate WJ

    更新日期:1989-01-01 00:00:00

  • Duodenal diverticula occurring in a family--chance or inheritance?

    abstract::The incidence, aetiology and possible inheritance of duodenal diverticula remain controversial. These aspects are discussed through the presentation of a family, in which duodenal diverticula occurred in a man and his two sons. To the best of our knowledge, this is the first such family documented in the medical liter...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.60.705.489

    authors: Sternberg A,Deutsch AA,Kott I,Reiss R

    更新日期:1984-07-01 00:00:00

  • Incidence of dual antiplatelet therapy interruption within 1 year after primary percutaneous coronary intervention in patients with acute ST elevation myocardial infarction.

    abstract:BACKGROUND:After primary percutaneous coronary intervention (PPCI) in patients with acute ST elevation myocardial infarction (STEMI), dual antiplatelet therapy (DAPT) is recommended to continue for 1 year. Occasionally, DAPT interruption may be required due to bleeding issues or unplanned surgical procedures. OBJECTIV...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2019-136760

    authors: Tam CC,Lee J,Chan KW,Lam CC,Wong YT,Chan E,Sze M,Lam YM,Chan C,Tse HF,Siu CW

    更新日期:2020-01-01 00:00:00

  • The normal range: it is not normal and it is not a range.

    abstract::The NHS 'Choose Wisely' campaign places greater emphasis on the clinician-patient dialogue. Patients are often in receipt of their laboratory data and want to know whether they are normal. But what is meant by normal? Comparator data, to a measured value, are colloquially known as the 'normal range'. It is often assum...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2018-135983

    authors: Whyte MB,Kelly P

    更新日期:2018-11-01 00:00:00

  • Introduction of clerking pro forma for surgical spinal patients at the Royal National Orthopaedic Hospital NHS Trust (London): an audit cycle.

    abstract::As a tertiary referral centre of spinal surgery, the Royal National Orthopaedic Hospital (RNOH) handles hundreds of spinal cases a year, often with complex pathology and complex care needs. Despite this, issues were raised at the RNOH following lack of sufficient documentation of preoperative and postoperative clinica...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2017-135498

    authors: Pace V,Farooqi O,Kennedy J,Park C,Cowan J

    更新日期:2018-05-01 00:00:00

  • Management of acute ventilatory failure.

    abstract::Acute ventilatory failure is a challenging yet increasingly common medical emergency reflecting the growing burden of respiratory disease. It is not a diagnosis in itself but the end result of a diversity of disease processes culminating in arterial hypoxaemia and hypercapnia. This review focuses on key management iss...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2005.043208

    authors: Chakrabarti B,Calverley PM

    更新日期:2006-07-01 00:00:00

  • Antibiotic prescription for patients referred to a specialist breast clinic.

    abstract::Hospital referral is indicated as an emergency for breast infections not settling with oral antibiotics. Referrals to a breast clinic over a period of 6 months were assessed for prior antibiotic prescription. A total of 1078 patients were seen during this period. 91 (8%) patients had been prescribed antibiotics, 71% o...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2006.049296

    authors: Twine C,Gateley CA

    更新日期:2006-11-01 00:00:00

  • Immunogenicity of a recombinant DNA hepatitis B vaccine in neonates.

    abstract::Infants of HBsAg-positive mothers (Group I) as well as those born to women without HBV markers (Group II) were vaccinated with a 10 micrograms dose of a recombinant DNA hepatitis B vaccine within 24 hours after birth according to a 0, 1, and 2 month schedule, with a booster dose planned 12 months later. Vaccination re...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:

    authors: Meheus A,Alisjahbana A,Vranckx R,Sukadi A,Usman A,Ngantung W,Sugita E,Safary A,André F,Reniers J

    更新日期:1987-01-01 00:00:00

  • Depression in primary care: three key challenges.

    abstract::The recognition and treatment of depression is a challenging area of clinical practice, especially in primary care where there are many patients with various presentations and a multitude of causes for distress. The prevalence of depression is increasing, and it is predicted to become second only to ischaemic heart di...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2008.068387

    authors: Lester H,Howe A

    更新日期:2008-10-01 00:00:00

  • Pancreatic ketoacidosis: ketonemia associated with acute pancreatitis.

    abstract::Ketonaemia is well documented as a consequence of prolonged starvation, acute alcoholism, and uncontrolled diabetes mellitus. However, its occurrence in acute pancreatitis has not been described. In this report, three patients who manifested ketoacidosis at the time of presentation of acute pancreatitis are described....

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.71.831.32

    authors: Kabadi UM

    更新日期:1995-01-01 00:00:00

  • Carcinoma of the duodenum.

    abstract::We report two patients with primary adenocarcinoma of the duodenum who underwent successful pancreatico-duodenectomy (modified Whipple operation). One patient died from an unrelated cause three years following surgery whilst the other remains well and clinically free of disease 3 years after resection. An aggressive s...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.63.744.907

    authors: Carragher A,Russell C

    更新日期:1987-10-01 00:00:00

  • Coeliac disease and goitre.

    abstract::Two cases of coeliac disease associated with thyroid enlargement are presented. One had a large simple adenomatous goitre which was removed surgically and the other had histological confirmation of lymphadenoma (Hashimoto's disease). ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.53.616.95

    authors: Robinson TJ

    更新日期:1977-02-01 00:00:00

  • Acute endoscopic intervention in non-variceal upper gastrointestinal bleeding.

    abstract::Upper gastrointestinal bleeding is one of the commonest emergencies encountered by general physicians. Once haemodynamic stability has been achieved, therapeutic endoscopy is vital in control and arrest of bleeding. Various methods are available and the evidence is reviewed as to the most optimal approach. Clinical pa...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2004.020867

    authors: Arasaradnam RP,Donnelly MT

    更新日期:2005-02-01 00:00:00

  • Pitfalls in the interpretation of common biochemical tests.

    abstract::This review considers some of the more common problems in the interpretation of the results of biochemical tests and, where possible, highlights ways in which errors can be identified or avoided. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pmj.76.893.129

    authors: Ayling RM

    更新日期:2000-03-01 00:00:00