Age at obesity and association with subsequent dementia: record linkage study.

abstract：AIM:To establish an updated clinical profile of adenocarcinoma of the lung. DESIGN:Retrospective review of clinical charts, chest radiography, and computed tomography of consecutive patients who attended Queen Mary Hospital in Hong Kong between June 1995 and December 1997. RESULTS:In the 115 patients studied, 13% wer...

journal_title：Postgraduate medical journal

authors： Lam B,Lam WK,Lam CL,Ooi GC,Ho JC,Wong MP,Tsang KW

更新日期：2001-11-01 00:00:00

abstract：:Muscarinic receptors are present on several different cells in lung and are predominantly involved in bronchoconstriction and mucus secretion. Muscarinic receptor activation leads to breakdown of phosphoinositides in airway smooth muscle cell membranes, which leads to intracellular calcium release and contraction. Mus...

journal_title：Postgraduate medical journal

authors： Barnes PJ

更新日期：1987-01-01 00:00:00

abstract：:The role of prostaglandins in inflammation is still disputed. Some workers have attempted to fit prostaglandins into a simple model, i.e. inflammatory leads to chemical mediator leads to vascular response. Recent work has shown that this approach may be misleading. An alternative model is proposed, involving the inter...

journal_title：Postgraduate medical journal

authors： Williams TJ

更新日期：1977-11-01 00:00:00

abstract：OBJECTIVE:To examine the current attitudes towards the prevention of venous thromboembolism among a cohort of surgeons. DESIGN:A postal survey, comprising a questionnaire covering various aspects of venous thromboembolism prophylaxis was sent to all (n=84) consultant general surgeons in Wales. RESULTS:Replies were re...

journal_title：Postgraduate medical journal

authors： Williams EV,Williams RS,Hughes JL,Williams KL,Foster ME,Lewis MH

更新日期：2002-02-01 00:00:00

abstract：:A multi-centre double-blind randomized study is reported in which the effect on mortality of oral disopyramide (300 mg loading dose, then 100 mg qds) was compared with placebo in 1985 patients entering hospital with suspected acute myocardial infarction. Treatment was commenced with 24 hr of onset of symptoms (mean ti...

journal_title：Postgraduate medical journal

authors：

更新日期：1984-02-01 00:00:00

abstract：:Motor neurone disease (MND), or amyotrophic lateral sclerosis (ALS), is a neurodegenerative disorder of unknown aetiology. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Confirming the diagnosis may initially be difficult until the full clinical features ar...

journal_title：Postgraduate medical journal

authors： Talbot K

更新日期：2002-09-01 00:00:00

abstract：:Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia...

journal_title：Postgraduate medical journal

authors： Braun GS,Horster S,Wagner KS,Ihrler S,Schmid H

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Transient ischaemic attacks (TIAs) carry a significant early risk of stroke. New national guidelines state patients should be seen within 7 days of the incident, with higher-risk patients being seen within 24 h. Meeting these targets across the NHS poses a significant challenge. A novel approach to TIA asses...

journal_title：Postgraduate medical journal

authors： Banerjee S,Natarajan I,Biram R,Sutton K,Ekeng G,Ames D,Chataway J

更新日期：2009-12-01 00:00:00

abstract：:Postherpetic neuralgia is defined as pain persisting, or recurring, at the site of shingles at least three months after the onset of the acute rash. Thus defined, at least half of shingles sufferers over the age of 65 years develop postherpetic neuralgia. In addition to increasing age, less important risk factors for ...

journal_title：Postgraduate medical journal

authors： Bowsher D

更新日期：1997-10-01 00:00:00

abstract：:Ruptured abdominal aortic aneurysm currently accounts for about 1 in 200 deaths and is a critical surgical emergency with an average hospital mortality of 50%. The combination of acute massive haemorrhage in an elderly patient with pre-existing medical disease is highly lethal and a major challenge for any health care...

journal_title：Postgraduate medical journal

authors： Brimacombe J,Berry A

更新日期：1994-04-01 00:00:00

abstract：:Proper understanding of the pathological process of a ruptured plaque followed by thrombus formation remains the basis for rational therapy of cardiac ischaemia and myocardial infarction. With the advent of better thrombolytic regimens, improved direct reperfusion via angioplasty and streamlined recognition/admission ...

journal_title：Postgraduate medical journal

authors： Hugenholtz PG

更新日期：1994-01-01 00:00:00

abstract：:Fistulous communications of the uterus are relatively unknown. We report in this paper the first case to our knowledge of uterocutaneous fistula which developed following a septic abortion induced by introduction of Laminaria tent into the uterus. ...

journal_title：Postgraduate medical journal

authors： Gupta SK,Shukla VK,Varma DN,Roy SK

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To audit the current UK outpatient workload and compare this to the national standards as set out by the British Association of Urological Surgeons (BAUS) in A Quality Urological Service for Patients in the New Millennium published in October 2000. PARTICIPANTS:520 UK (NHS) and 21 Republic of Ireland (non-NH...

journal_title：Postgraduate medical journal

authors： Gilmore PE,Shackley DC,Clarke NW,Betts CD,O'Flynn KJ

更新日期：2005-01-01 00:00:00

abstract：:Heart failure is a major problem worldwide; it is the leading cause of hospitalisation and is posing a huge financial burden. Advances in healthcare have contributed to increased life expectancy, with a resultant increase in the number of patients with chronic heart failure. For many patients who are still severely sy...

journal_title：Postgraduate medical journal

authors： Patel S,Nicholson L,Cassidy CJ,Wong KY

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:For gastroenterology, The Royal College of Physicians reiterates the common practice of two to three consultant ward rounds per week. The Royal Bolton Hospital NHS Foundation Trust operated a 26-bed gastroenterology ward, covered by two consultants at any one time. A traditional system of two ward rounds per...

journal_title：Postgraduate medical journal

authors： Singh S,Lipscomb G,Padmakumar K,Ramamoorthy R,Ryan S,Bates V,Crompton S,Dermody E,Moriarty K

更新日期：2012-10-01 00:00:00

abstract：:The term "natural childbirth" denotes an approach to childbirth characterised by a bias towards physical and mental hygiene in the management of pregnancy and labour. It emerged in Britain in the interwar period, partly as a response to the growing interventionism of mainstream obstetrics. Its appeal since then has re...

journal_title：Postgraduate medical journal

authors： Moscucci O

更新日期：2003-03-01 00:00:00

abstract：:Three women were admitted to the surgical wards with acute gastro-intestinal symptoms and despite good clinical (pigmentation, hypotension) and biochemical (hyponatraemia, acidosis) evidence of Addisonian crisis had unnecessary investigations with delay in the diagnosis and appropriate management of this medical emerg...

journal_title：Postgraduate medical journal

authors： Small M,MacCuish AC,Thomson JA

更新日期：1987-05-01 00:00:00

abstract：:Renal disease in Churg-Strauss syndrome is generally thought to be benign in nature, thereby distinguishing this rare condition from other necrotizing vasculitides. We report a case in which acute renal failure developed during the aggressive vasculitic phase of the illness requiring dialysis therapy. After one week o...

journal_title：Postgraduate medical journal

authors： Davenport A,McDicken I,Goldsmith HJ

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Randomised controlled trials (RCTs) have shown that endoscopic haemostasis is beneficial for patients with a bleeding peptic ulcer. The relevance of such data to management outside of RCTs is unclear. Therefore we examined management of patients with a bleeding peptic ulcer in a UK teaching hospital. METHOD...

journal_title：Postgraduate medical journal

authors： Mahadeva S,Linch M,Hull MA

更新日期：2002-06-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is common and may progress to cirrhosis and its complications. The pathogenesis of steatosis and cellular injury is thought to be related mostly to insulin resistance and oxidative stress. Therefore, management entails identification and treatment of metabolic risk factors, im...

journal_title：Postgraduate medical journal

authors： Adams LA,Angulo P

更新日期：2006-05-01 00:00:00

abstract：:In recent years, the short Synacthen test (SS) has become the most widely used test to assess adrenal reserve. Despite its frequent use, there are still several areas related to the short Synacthen test (SST), which have no consensus including the optimum sampling times, that is, whether a 60 min post-Synacthen admini...

journal_title：Postgraduate medical journal

authors： Dineen R,Mohamed A,Gunness A,Rakovac A,Cullen E,Barnwell N,Neary C,Behan LA,Boran G,Gibney J,Sherlock M

更新日期：2020-02-01 00:00:00

abstract：:The anti-hypertensive effect of 250 mg tienilic acid was comparable to that of 50 mg hydrochlorothiazide. Unlike hydrochlorothiazide, tienilic acid caused a statistically significant decrease in the serum uric acid values. Clinically non-significant rises in blood urea nitrogen and serum creatinine occurred with both ...

journal_title：Postgraduate medical journal

authors： McMahon FG,Ryan JR,Jain AK

更新日期：1979-01-01 00:00:00

abstract：:Eight patients with endobronchial tuberculosis diagnosed on bronchoscopy were treated with antituberculosis drugs and a course of prednisone. The progress of the endobronchial lesions was assessed on repeated examinations. The course of the disease was variable and the endobronchial narrowing improved in two patients ...

journal_title：Postgraduate medical journal

authors： Chan HS,Sun A,Hoheisel GB

更新日期：1990-10-01 00:00:00

abstract：:Submucosal dissection of the oesophagus is a rare oesophageal disorder. We report a patient who had recurrent episodes of dissection and achalasia. Both recurrence and the association with achalasia are to our knowledge unique. ...

journal_title：Postgraduate medical journal

authors： Hooper TL,Gholkar J,Smith SR,Manns JJ,Moussalli H

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of, and implement a diagnostic strategy for, imported helminth infection in the gastroenterology clinic. DESIGN:A retrospective study of eosinophil count and probable tropical exposure (phase I) followed by a prospective study of parasitological investigation (phase II). SETTING:G...

journal_title：Postgraduate medical journal

authors： Smith PJ,Theis B,McCartney S,Brown M

更新日期：2012-01-01 00:00:00

abstract：:We report a case of severe chronic iron deficiency anaemia secondary to blood loss from gastric angiodysplasia. The clinical features, diagnosis and management of this uncommon condition are discussed. ...

journal_title：Postgraduate medical journal

authors： Tung KT,Millar AB

更新日期：1987-10-01 00:00:00

abstract：:The occurrence of ketoacidosis in out-patient diabetics treated with continuous subcutaneous insulin infusion (CSII) has received little attention. We report two such cases of ketosis, each precipitated by infection and occurring in patients previously well controlled on CSII. This report illustrates that the risk of ...

journal_title：Postgraduate medical journal

authors： Boulton AJ,Knight G,Drury J,Ward JD

更新日期：1983-07-01 00:00:00

abstract：:A case of adenocarcinoma of the lung, in which high titre anticardiolipin antibodies were associated with recurrent venous thromboses resistant to all forms of therapy, is described. It is suggested that such an autoimmune response may be a contributory factor in the para-neoplastic development of vascular thromboses....

journal_title：Postgraduate medical journal

authors： Shaukat MN,Hughes P

更新日期：1990-04-01 00:00:00

abstract：:Repeated pneumonia and hypogammaglobulinaemia was associated with long term low dose steroid therapy. Clinical improvement with restoration of antibody levels followed substitution of aerosol for oral therapy. ...

journal_title：Postgraduate medical journal

authors： Lee RJ,Fay AC

更新日期：1985-06-01 00:00:00

abstract：:Fungal infections of the central nervous system present a considerable challenge to available chemotherapy and other forms of treatment. The particular difficulties are discussed here, after an account of the fungi involved and their sensitivity to antifungal agents. Cryptococcal, coccidioidal and candidal infections ...

journal_title：Postgraduate medical journal

authors： Speller DC

更新日期：1979-09-01 00:00:00