Motor neurone disease.

abstract：:We describe the cases of two young women who died due to air embolism during sexual intercourse early in the puerperium. ...

journal_title：Postgraduate medical journal

authors： Batman PA,Thomlinson J,Moore VC,Sykes R

更新日期：1998-10-01 00:00:00

abstract：:The NHS 'Choose Wisely' campaign places greater emphasis on the clinician-patient dialogue. Patients are often in receipt of their laboratory data and want to know whether they are normal. But what is meant by normal? Comparator data, to a measured value, are colloquially known as the 'normal range'. It is often assum...

journal_title：Postgraduate medical journal

authors： Whyte MB,Kelly P

更新日期：2018-11-01 00:00:00

abstract：:Muscarinic receptors are present on several different cells in lung and are predominantly involved in bronchoconstriction and mucus secretion. Muscarinic receptor activation leads to breakdown of phosphoinositides in airway smooth muscle cell membranes, which leads to intracellular calcium release and contraction. Mus...

journal_title：Postgraduate medical journal

authors： Barnes PJ

更新日期：1987-01-01 00:00:00

abstract：:Although primary percutaneous coronary intervention (PCI) in clinical trials has lower rates of reinfarction, stroke and mortality than fibrinolytic therapy, because of system delays in routine practice, field triage and prehospital administration of fibrinolytic therapy may lead to similar clinical outcomes, especial...

journal_title：Postgraduate medical journal

authors： Edmond JJ,Juergens CP,French JK

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF THE STUDY:There are approximately 35 000 in-hospital cardiac arrests in the UK each year. Successful resuscitation requires integration of the medical science, training and education of clinicians and implementation of best practice in the clinical setting. In 2015, the International Liaison Committee on Res...

journal_title：Postgraduate medical journal

authors： Carberry J,Couper K,Yeung J

更新日期：2017-11-01 00:00:00

abstract：:A 72 year old man developed acute myeloblastic leukaemia two years after he had been treated with local curative therapy and chemotherapy for a solitary plasma cytoma of the ilium. ...

journal_title：Postgraduate medical journal

authors： Maharaj D,Dolan G

更新日期：1986-12-01 00:00:00

abstract：:A 28 year old female patient with Cushing's syndrome due to an adrenal adenoma also suffered from recurrent urinary infections (proteus), tonsillitis (streptococcus), permanent candidiasis and perimandibular abscess (Staphylococcus pyogenes). Suppression of cellular and humoral immunity was confirmed by in vitro tests...

journal_title：Postgraduate medical journal

authors： Würzburger MI,Prelević GM,Brkić SD,Vucković S,Pendić B

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Right ventricular (RV) fractional area change and tricuspid annular plane systolic excursion (TAPSE) are recognised methods for assessing RV function. However, the way in which these variables are affected by varying degrees of pulmonary hypertension (PH) has not been well characterised. METHODS:RV end-syst...

journal_title：Postgraduate medical journal

authors： López-Candales A,Dohi K,Rajagopalan N,Edelman K,Gulyasy B,Bazaz R

更新日期：2008-01-01 00:00:00

abstract：:A patient with long-standing ischaemic heart disease and severe low output congestive cardiac failure received numerous diuretics, which gradually became ineffective. Resistant oedema was treated by adding demeclocycline to the current diuretic regime of frusemide and metolazone. Diuresis resulted, oedema disappeared ...

journal_title：Postgraduate medical journal

authors： Bonser RS,Ghose RR

更新日期：1980-02-01 00:00:00

abstract：:There is considerable evidence to suggest that the identification and treatment of dyslipidaemia will reduce the risk of premature CHD, i.e. before the age of 65. Diagnosis of the cause of raised plasma lipid levels will enable appropriate decisions to be taken with regard to management. The cornerstone of treatment i...

journal_title：Postgraduate medical journal

authors： Betteridge DJ,Dodson PM,Durrington PN,Hughes EA,Laker MF,Nicholls DP,Rees JA,Seymour CA,Thompson GR,Winder AF

更新日期：1993-05-01 00:00:00

abstract：:A patient with chronic pancreatitis presented with a series of massive upper gastrointestinal haemorrhages due to bleeding into the pancreatic duct. This report emphasizes the value of intensive investigation before surgery, since it may be impossible to identify the site of bleeding at laparotomy. ...

journal_title：Postgraduate medical journal

authors： Ribbans WJ,Pounder RE,Lindsay I

更新日期：1985-06-01 00:00:00

abstract：:The Supreme Court judgement in 'Montgomery v Lanarkshire Health Board' has caused a change in the law concerning the duty of doctors on disclosure of information to patients regarding risks. The law now requires a doctor to take reasonable care to ensure that the patient is aware of any material risks involved in any ...

journal_title：Postgraduate medical journal

authors： Lee A

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To audit the current UK outpatient workload and compare this to the national standards as set out by the British Association of Urological Surgeons (BAUS) in A Quality Urological Service for Patients in the New Millennium published in October 2000. PARTICIPANTS:520 UK (NHS) and 21 Republic of Ireland (non-NH...

journal_title：Postgraduate medical journal

authors： Gilmore PE,Shackley DC,Clarke NW,Betts CD,O'Flynn KJ

更新日期：2005-01-01 00:00:00

abstract：:Bilateral subconjunctival haemorrhage was observed on 5 separate occasions in 4 patients presenting a fulminant form of acute severe asthma. Four of these episodes required ventilatory support. All patients recovered from their asthma attack after treatment with bronchodilators, corticosteroids, and oxygen. The incide...

journal_title：Postgraduate medical journal

authors： Rodriguez-Roisin R,Torres A,Agustí AG,Ussetti P,Agustí-Vidal A

更新日期：1985-07-01 00:00:00

abstract：:Coagulation problems in pregnancy are primarily associated with overactivity of the intrinsic clotting system. This accounts for the increased incidence of thrombo-embolism during pregnancy. Where specific obstetric complications cause clotting problems the common underlying feature is usually placental pathology as i...

journal_title：Postgraduate medical journal

authors： Redman CW

更新日期：1979-05-01 00:00:00

abstract：:The frequency and characteristics of chest pain and non-respiratory symptoms were investigated in patients admitted with acute asthma. One hundred patients with a mean admission peak flow rate of 38% normal or predicted were interviewed using a questionnaire. Chest pain occurred in 76% and was characteristically a dul...

journal_title：Postgraduate medical journal

authors： Edmondstone WM

更新日期：2000-07-01 00:00:00

abstract：:There has been a dramatic change in the way that resuscitation decisions are made for older hospital inpatients in the UK. In less than 20 years many geriatric medicine wards have moved from an "opt-in" policy (where the default position is not to provide resuscitation) to a position where resuscitation is widely avai...

journal_title：Postgraduate medical journal

authors： Bowker L

更新日期：2009-11-01 00:00:00

abstract：:The nature of rehabilitation medicine is outlined in terms of its objectives, its methods, the patient groups which it seeks to help and its relationships to other specialties. Some major advances of recent years are discussed, such as the development of the impairment/disability/handicap framework. With particular em...

journal_title：Postgraduate medical journal

authors： Cozens JA,Chamberlain MA

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:There is paucity of evidence regarding the role of drain in laparoscopic cholecystectomy (LC) in acute calculous cholecystitis (ACC), and surgeons have placed the drains based on their experiences, not on evidence-based guidelines. This study aims to assess the value of drain in LC for ACC in a randomised co...

journal_title：Postgraduate medical journal

authors： Valappil MV,Gulati S,Chhabra M,Mandal A,Bakshi S,Bhattacharyya A,Ghatak S

更新日期：2020-10-01 00:00:00

abstract：:The prognosis of patients with metastatic adrenal cortical carcinoma is poor, and their disabling symptoms are usually unresponsive to conventional therapy. A patient with Cushing's syndrome secondary to a secretory adrenal cortical carcinoma was treated with octreotide, endocrine therapy and chemotherapy having faile...

journal_title：Postgraduate medical journal

authors： Pandha HS,Harrington K,Saini S,Lynn J,Peters M,Waxman J

更新日期：1995-04-01 00:00:00

abstract：:A 77-year old woman with pituitary-driven Cushing's disease is described. The condition was completely controlled on long-term treatment with metyrapone. ...

journal_title：Postgraduate medical journal

authors： Donckier J,Burrin JM,Ramsay ID,Joplin GF

更新日期：1986-08-01 00:00:00

abstract：:In a routine adult gastroenterological practice, seventeen (15%) of 123 patients had small-intestinal biopsies which were neither normal nor were completely flat as found in classical coeliac disease. Some of these had a possible cause for the mild mucosal abnormality, but in six there was no other apparent cause and ...

journal_title：Postgraduate medical journal

authors： Scott BB,Losowsky MS

更新日期：1977-03-01 00:00:00

abstract：:Juvenile myoclonic epilepsy (JME) is a hereditary, idiopathic, generalised epilepsy and is found in 5%-11% of patients with epilepsy. It is characterised by myoclonic jerks, occasional generalised tonic-clonic seizures, and sometimes absence seizures. JME continues to be under-appreciated and under-diagnosed. Accurate...

journal_title：Postgraduate medical journal

authors： Renganathan R,Delanty N

更新日期：2003-02-01 00:00:00

abstract：:The risk of developing an overt malignancy after an isolated deep venous thrombosis (DVT) is poorly documented. We therefore reviewed a series of patients in whom a solitary idiopathic DVT had been proven by venography at least 12 months earlier. No patient had developed a malignancy at follow-up. However, decreased f...

journal_title：Postgraduate medical journal

authors： O'Connor NT,Cederholm-Williams SA,Fletcher EW,Allington M,Sharp AA

更新日期：1984-04-01 00:00:00

abstract：:Two cases of widespread cutaneous vasculitis are described in association with diltiazem, a recently introduced calcium antagonist. In both cases, spontaneous resolution occurred over several weeks following withdrawal of the drug. ...

journal_title：Postgraduate medical journal

authors： Sheehan-Dare RA,Goodfield MJ

更新日期：1988-06-01 00:00:00

abstract：:Evidence is now accumulating on both clinical and experimental grounds that the retina is an a priori source of inflammatory activity. Reactive inflammation in the retina may produce many of the clinical signs previously ascribed to uveal inflammation. Autoimmune mechanisms are probably responsible for the majority of...

journal_title：Postgraduate medical journal

authors： Sanders MD,Graham EM

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:After primary percutaneous coronary intervention (PPCI) in patients with acute ST elevation myocardial infarction (STEMI), dual antiplatelet therapy (DAPT) is recommended to continue for 1 year. Occasionally, DAPT interruption may be required due to bleeding issues or unplanned surgical procedures. OBJECTIV...

journal_title：Postgraduate medical journal

authors： Tam CC,Lee J,Chan KW,Lam CC,Wong YT,Chan E,Sze M,Lam YM,Chan C,Tse HF,Siu CW

更新日期：2020-01-01 00:00:00

abstract：:Serum thyrotrophin has been measured before and after the intravenous administration of 200 micrograms of thyrotrophin-releasing hormone in 91 white subjects (33 stable diabetic patients and 58 healthy controls), none of whom had any clinical evidence of thyroid or pituitary dysfunction. Seven of the diabetic subjects...

journal_title：Postgraduate medical journal

authors： Small M,Cohen HN,MacLean JA,Beastall GH,MacCuish AC

更新日期：1986-06-01 00:00:00

abstract：:The effect of beta-blockers in improving exercise tolerance in angina pectoris can be accounted for by the reduction in heart rate and arterial pressure than they produce. The failure of a few patients to respond despite reduction in heart rate and the failure of those who do respond to obtain the full expected benefi...

journal_title：Postgraduate medical journal

authors： Robinson BF

更新日期：1976-01-01 00:00:00

abstract：:The role of prostaglandins in inflammation is still disputed. Some workers have attempted to fit prostaglandins into a simple model, i.e. inflammatory leads to chemical mediator leads to vascular response. Recent work has shown that this approach may be misleading. An alternative model is proposed, involving the inter...

journal_title：Postgraduate medical journal

authors： Williams TJ

更新日期：1977-11-01 00:00:00