Cushing's syndrome--transitory immune deficiency state?

abstract：:Phyllodes tumours are rare fibroepithelial lesions that account for less than 1% of all breast neoplasms. With the non-operative management of fibroadenomas widely adopted, the importance of phyllodes tumours today lies in the need to differentiate them from other benign breast lesions. All breast lumps should be trip...

journal_title：Postgraduate medical journal

authors： Parker SJ,Harries SA

更新日期：2001-07-01 00:00:00

abstract：:There is an increasing awareness on the part both of the media and the profession of the need to co-operate in providing information and education on medical matters. This co-operation should be strongly encouraged. Where children are concerned the opportunities for education are great. ...

journal_title：Postgraduate medical journal

authors： Jolly H

更新日期：1978-03-01 00:00:00

abstract：:Hypercalcaemia occurs in up to 80% of patients with adult T-cell leukaemia-lymphoma (ATLL) associated with human T-cell leukaemia virus-1 infection. Elevated serum levels of 1,25-dihydroxycholecalciferol, implicated in the pathogenesis of hypercalcaemia in lymphoma, and of parathyroid hormone-related protein (PTHrP), ...

journal_title：Postgraduate medical journal

authors： Johnston SR,Hammond PJ

更新日期：1992-09-01 00:00:00

abstract：:By comparison with other calcium antagonist drugs, amlodipine has unique pharmacokinetic properties that are probably attributable to its chemical structure and positive ionic charge at physiological pH. Thus, amlodipine undergoes gradual absorption from the gastro-intestinal tract and is widely distributed throughout...

journal_title：Postgraduate medical journal

authors： Elliott HL,Meredith PA

更新日期：1991-01-01 00:00:00

abstract：:Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia...

journal_title：Postgraduate medical journal

authors： Braun GS,Horster S,Wagner KS,Ihrler S,Schmid H

更新日期：2007-02-01 00:00:00

abstract：:A patient is described who developed acute pericarditis during a severe first attack of Crohn's disease. The opportunity was taken to measure levels of circulating immune complexes, both during the acute phase of the illness and during convalescence; no significant change in these levels from normal values was found. ...

journal_title：Postgraduate medical journal

authors： Manomohan V,Subbuswamy SG,Willoughby CP

更新日期：1984-10-01 00:00:00

abstract：:A 58 year old man presented with an anterior myocardial infarction requiring repeated resuscitation. He had impaired glucose tolerance. He died five weeks later and post-mortem examination revealed a myocardial abscess and sternal osteomyelitis due to Staphylococcus aureus. These had not been apparent clinically. The ...

journal_title：Postgraduate medical journal

authors： Smith RE,Martin JE,Mills PG

更新日期：1989-08-01 00:00:00

abstract：:The Royal Hospital for Incurables (RHI), now known as the Royal Hospital for Neuro-Disability and situated on West Hill, Putney, was founded by Andrew Reed DD exactly 150 years ago. The RHI was thus the pioneer in modern times of long stay institutions for the sick and dying. It became one of the great Victorian chari...

journal_title：Postgraduate medical journal

authors： Cook GC

更新日期：2004-07-01 00:00:00

abstract：:This paper reviews briefly the place of ipratropium bromide in the treatment of airways obstruction. Oxitropium bromide, a new quaternary ammonium compound derived from scopolamine was shown to be as effective a bronchodilator in a dose of 200 micrograms by inhalation as ipratropium bromide 80 micrograms in 20 patient...

journal_title：Postgraduate medical journal

authors： Anderson G

更新日期：1983-01-01 00:00:00

abstract：:Verrucous carcinoma is a rare skin malignancy of squamous cell origin. It is characterised by negligible cellular atypia and a low mitotic rate. These are reflected in slow locally invasive behaviour and very infrequent metastatic spread. The tumour is also recognised in oral and anogenital sites. Cutaneous lesions pr...

journal_title：Postgraduate medical journal

authors： Munro NA,Smith C,Purushotham AD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Epidemiological and family studies suggest that lung cancer results from the combined effects of age, smoking and genetic factors. Chronic obstructive pulmonary disease (COPD) is also an independent risk factor for lung cancer and coexists in 40-60% of lung cancer cases. METHODS:In a two-stage case-control ...

journal_title：Postgraduate medical journal

authors： Young RP,Hopkins RJ,Hay BA,Epton MJ,Mills GD,Black PN,Gardner HD,Sullivan R,Gamble GD

更新日期：2009-10-01 00:00:00

abstract：:Current maintenance immunosuppressive regimens for transplantation are based on three classes of drugs: corticosteroids, immunophilin-binding agents (eg, cyclosporin and tacrolimus), and antimetabolites (eg, azathioprine and mycophenolate). Drugs from the various classes inhibit the immune system at different points a...

journal_title：Postgraduate medical journal

authors： Vella JP,Sayegh MH

更新日期：1997-07-01 00:00:00

abstract：:In a routine adult gastroenterological practice, seventeen (15%) of 123 patients had small-intestinal biopsies which were neither normal nor were completely flat as found in classical coeliac disease. Some of these had a possible cause for the mild mucosal abnormality, but in six there was no other apparent cause and ...

journal_title：Postgraduate medical journal

authors： Scott BB,Losowsky MS

更新日期：1977-03-01 00:00:00

abstract：:Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal ...

journal_title：Postgraduate medical journal

authors： McRipley RJ,Erhard PJ,Schwind RA,Whitney RR

更新日期：1979-09-01 00:00:00

abstract：:A 22 year old woman was admitted with amitriptyline overdose. Twenty six hours later she developed acute myocardial infarction. Cardiotoxic effects of tricyclic antidepressants are discussed and the importance of considering myocardial infarction as a complication of tricyclic antidepressant overdose is emphasized. ...

journal_title：Postgraduate medical journal

authors： Chamsi-Pasha H,Barnes PC

更新日期：1988-12-01 00:00:00

abstract：:The efficacy of ranitidine (150 mg twice daily) and cimetidine (200 mg three times daily and 400 mg at night) in the short-term healing of duodenal ulcer has been assessed in a randomized controlled trial involving 106 patients. There were 3 drop-outs. Forty-two out of 53 patients (79%) treated with ranitidine had hea...

journal_title：Postgraduate medical journal

authors： Lee FI,Fielding JD,Costello FT

更新日期：1983-02-01 00:00:00

abstract：:Acute bacterial meningitis is a common neurological emergency and a leading cause of death and neurological disability worldwide. Diagnosis is based on clinical and microbiological findings with neuroimaging in the form of CT reserved for those with specific adverse clinical features or when an underlying cause such a...

journal_title：Postgraduate medical journal

authors： Hughes DC,Raghavan A,Mordekar SR,Griffiths PD,Connolly DJ

更新日期：2010-08-01 00:00:00

abstract：:Patients with Cushing's syndrome rarely become pregnant. This is a high risk situation both for the fetus and the mother, if untreated. We report a patient with Cushing's syndrome due to adrenocortical adenoma who became pregnant and was successfully treated with ketoconazole during the last period of pregnancy. ...

journal_title：Postgraduate medical journal

authors： Amado JA,Pesquera C,Gonzalez EM,Otero M,Freijanes J,Alvarez A

更新日期：1990-03-01 00:00:00

abstract：:A case of seminoma of the testis complicated by an extensive granulomatous reaction is reported. This reaction was so florid that a benign condition was initially considered until further material for histology was examined and the correct diagnosis made. ...

journal_title：Postgraduate medical journal

authors： Pickard WR,Clark AH,Abel BJ

更新日期：1983-05-01 00:00:00

abstract：:Coeliac disease is exacerbated by wheat gluten. A review of methods for the purification, identification and quantitation of wheat proteins to investigate coeliac disease is presented. Recent developments including amino acid sequencing and expression of wheat protein peptides in E. coli should permit characterization...

journal_title：Postgraduate medical journal

authors： Ciclitira PJ,Ellis HJ

更新日期：1987-09-01 00:00:00

abstract：:Acute ventilatory failure is a challenging yet increasingly common medical emergency reflecting the growing burden of respiratory disease. It is not a diagnosis in itself but the end result of a diversity of disease processes culminating in arterial hypoxaemia and hypercapnia. This review focuses on key management iss...

journal_title：Postgraduate medical journal

authors： Chakrabarti B,Calverley PM

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Randomised controlled trials (RCTs) have shown that endoscopic haemostasis is beneficial for patients with a bleeding peptic ulcer. The relevance of such data to management outside of RCTs is unclear. Therefore we examined management of patients with a bleeding peptic ulcer in a UK teaching hospital. METHOD...

journal_title：Postgraduate medical journal

authors： Mahadeva S,Linch M,Hull MA

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:Effective communication is a vital part of good clinical care. Traditionally bleep systems have been used as the mainstay of communication. Mobile technology is increasingly seen as a quicker, easier and more reliable method of communication. Our objective was to assess the use of mobile devices within a typ...

journal_title：Postgraduate medical journal

authors： Martin G,Janardhanan P,Withers T,Gupta S

更新日期：2016-09-01 00:00:00

abstract：:Antenatal appendicular perforation leading to localized meconium peritonitis and intestinal obstruction is reported in a premature neonate. The baby was successfully treated by a limited ileocaecal resection. ...

journal_title：Postgraduate medical journal

authors： Narasimharao KL,Mitra SK,Pathak IC

更新日期：1987-11-01 00:00:00

abstract：:Thirty-one patients with radiolucent common bile duct stones received medical treatment. Nineteen had Rowachol, a terpene preparation, eight (42%) achieving complete stone disappearance within 3 to 48 months. Fifteen (including 3 of the above) took Rowachol with bile acid (chenodeoxycholic in 11, ursodeoxycholic in 4)...

journal_title：Postgraduate medical journal

authors： Somerville KW,Ellis WR,Whitten BH,Balfour TW,Bell GD

更新日期：1985-04-01 00:00:00

abstract：:Digital clubbing has been a well recognised feature of several distinct clinical conditions, including respiratory, cardiac, and gastrointestinal diseases since the Hippocratic era. However, clubbing associated with Behçet's disease has not been reported before. We describe a case of clubbing in a young man with Behçe...

journal_title：Postgraduate medical journal

authors： Benekli M,Güllü IH

更新日期：1997-09-01 00:00:00

abstract：:Common bile duct perforation causing biliary peritonitis is an unusual entity and a pancreatic calculus causing this perforation is all the more rare, and to our knowledge has not been reported previously. Such an unusual presentation of chronic calcific pancreatitis is herein reported. ...

journal_title：Postgraduate medical journal

authors： Kumar A,Kataria R,Chattopadhyay TK,Karak PK,Tandon RK

更新日期：1992-10-01 00:00:00

abstract：:Two patients with sarcoidosis and glomerular mesangial proliferative lesions are described. Although a causative relationship between sarcoidosis and glomerulonephritis has been suggested, critical review of the literature fails to confirm this. ...

journal_title：Postgraduate medical journal

authors： Howard RS,Gabriel R

更新日期：1992-03-01 00:00:00

abstract：:A young man who presented with a 3 week history of fever and severe headache accompanied by mild leukocytosis, was found to have lymphocytic meningitis due to Coxiella burnetti. Thus, Q fever can present as lymphocytic (aseptic) meningitis responsive to tetracycline with no evidence of pulmonary involvement. ...

journal_title：Postgraduate medical journal

authors： Schattner A,Kushnir M,Zhornicky T,Fenakel G

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:To assess the evidence for a reduced risk of acute coronary events following comprehensive smoke-free legislation. METHODS:Two independent systematic reviews were undertaken using PubMed, Embase and Science Direct with no date restrictions imposed. Meta-analysis was undertaken using a random effects model to...

journal_title：Postgraduate medical journal

authors： Mackay DF,Irfan MO,Haw S,Pell JP

更新日期：2011-04-01 00:00:00