Maintenance pharmacological immunosuppressive strategies in renal transplantation.

abstract：:Patients with acquired von Willebrand disease may present with severe bleeding, which is usually difficult to manage. Adequate haemostasis in acquired von Willebrand disease may be achieved with the infusion of factor VIII/von Willebrand factor concentrates or with the administration of desmopressin. We report a case ...

journal_title：Postgraduate medical journal

authors： Van Genderen PJ,Papatsonis DN,Michiels JJ,Wielenga JJ,Stibbe J,Huikeshoven FJ

更新日期：1994-12-01 00:00:00

abstract：:Paradoxical vocal cord motion disorder (PVCM), also called vocal cord dysfunction, is an important differential diagnosis for asthma. The disorder is often misdiagnosed as asthma leading to unnecessary drug use, very high medical utilisation and occasionally tracheal intubation or tracheostomy. Laryngoscopy is the gol...

journal_title：Postgraduate medical journal

authors： Ibrahim WH,Gheriani HA,Almohamed AA,Raza T

更新日期：2007-03-01 00:00:00

abstract：:A patient with Laurence-Moon-Biedl syndrome and nephrotic range proteinuria is presented. Radiological investigation of the urinary tract revealed clubbed calyces but no evidence of obstruction or vesicoureteric reflux. Renal biopsy revealed occasional sclerotic glomeruli, extensive foot-process fusion and segmental g...

journal_title：Postgraduate medical journal

authors： Cheng IK,Chan KW,Chan MK,Kung A,Ma J,Wang C

更新日期：1988-08-01 00:00:00

abstract：:Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage as defined by the UICC-TNM and American Joint Committee on Cancer classifications. Tumour extent, lymph node status, tumour grade and the assessment of lymphatic and venous invasion are still the most important morphological progn...

journal_title：Postgraduate medical journal

authors： Zlobec I,Lugli A

更新日期：2008-08-01 00:00:00

abstract：:The management of hyperthyroidism and hypothyroidism in pregnancy is discussed and illustrated with appropriate cases. The dangers of the usage of high doses of antithyroid drugs and of propranolol are described. ...

journal_title：Postgraduate medical journal

authors： Edwards OM

更新日期：1979-05-01 00:00:00

abstract：:Tissue auto-antibodies were investigated in fifty-one patients (twenty-five female, twenty-six male) receiving practolol for ischaemic heart disease or dysrhythmias and compared with those found in 204 patients (fifty-eight female, 146 male) with ischaemic heart disease who did not receive practolol. Antinuclear facto...

journal_title：Postgraduate medical journal

authors： Jachuck SJ,Stephenson J,Bird T,Jackson FS,Clark F

更新日期：1977-02-01 00:00:00

abstract：:Strips form canine saphenous veins were incubated with (3H)-noradrenaline and mounted for superfusion. 5-Hydroxytryptamine (5-HT inhibited the release of tritium caused by sustained electrical stimulation (2 Hz, 150 mA, 0.1 msec) being about 10 times more potent than noradrenaline. 5-HT inhibited contractions induced ...

journal_title：Postgraduate medical journal

authors： Müller-Schweinitzer E

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVES:Appropriate assessment of community-acquired pneumonia (CAP) allows accurate severity scoring and hence optimal management, leading to reduced morbidity and mortality. British Thoracic Society (BTS) guidelines provide an appropriate score. Adherence to BTS guidelines was assessed in our medical assessment un...

journal_title：Postgraduate medical journal

authors： Collini P,Beadsworth M,Anson J,Neal T,Burnham P,Deegan P,Beeching N,Miller A

更新日期：2007-08-01 00:00:00

abstract：:There has been a dramatic change in the way that resuscitation decisions are made for older hospital inpatients in the UK. In less than 20 years many geriatric medicine wards have moved from an "opt-in" policy (where the default position is not to provide resuscitation) to a position where resuscitation is widely avai...

journal_title：Postgraduate medical journal

authors： Bowker L

更新日期：2009-11-01 00:00:00

abstract：:The effect of captopril monotherapy on blood pressure and metabolism was investigated in a placebo-controlled study in 30 non-insulin dependent (Type II) diabetic subjects during a 3-week observation period (run-in/drug; placebo/wash-out) on a metabolic ward. Captopril significantly reduced both systolic and diastolic...

journal_title：Postgraduate medical journal

authors： Rett K,Wicklmayr M,Tschollar W,Dietze G,Mehnert H

更新日期：1988-01-01 00:00:00

abstract：:The introduction of spiral technology to computed tomography (CT) scanners in the late 1980s has revolutionised the field of CT. Spiral CT offers definite practical benefits over conventional scanners and has expanded the role of CT through the development of new scanning techniques. CT scanning now rivals magnetic re...

journal_title：Postgraduate medical journal

authors： Kearney SE,Garvey CJ

更新日期：1998-02-01 00:00:00

abstract：:We describe the cases of two young women who died due to air embolism during sexual intercourse early in the puerperium. ...

journal_title：Postgraduate medical journal

authors： Batman PA,Thomlinson J,Moore VC,Sykes R

更新日期：1998-10-01 00:00:00

abstract：:The recognition and treatment of depression is a challenging area of clinical practice, especially in primary care where there are many patients with various presentations and a multitude of causes for distress. The prevalence of depression is increasing, and it is predicted to become second only to ischaemic heart di...

journal_title：Postgraduate medical journal

authors： Lester H,Howe A

更新日期：2008-10-01 00:00:00

abstract：:Rhabdomyolysis is a rare but potentially fatal complication of hyperosmolar states. We report a case of severe hyperosmolar non-ketotic diabetic coma causing rhabdomyolysis in a young man. Despite very high levels of creatine kinase there was no detectable myoglobinuria. Creatine kinase estimation should be a standard...

journal_title：Postgraduate medical journal

authors： Trump D,O'Hanlon S,Rinsler M,Sharp P

更新日期：1994-01-01 00:00:00

abstract：:Synovial plicae are normal anatomical structures of the knee that may become symptomatic. MRI is an established technique for evaluating the anatomy of the knee, and it is a valuable tool for detecting plicae because of its high resolution resulting in increased tissue characterisation. At MRI, knee plicae appear as l...

journal_title：Postgraduate medical journal

authors： Vassiou K,Vlychou M,Zibis A,Nikolopoulou A,Fezoulidis I,Arvanitis D

更新日期：2015-01-01 00:00:00

abstract：:We describe two cases of digoxin toxicity presenting with clinical and electroencephalographic evidence of encephalopathy without other features of digoxin toxicity. ...

journal_title：Postgraduate medical journal

authors： Greenaway JR,Abuaisha B,Bramble MG

更新日期：1996-06-01 00:00:00

abstract：:A series of 8 adult patients with stable bronchial asthma and an established diagnois of essential hypertension (WHO I and II) was studied in a randomized double-blind cross-over study to assess the effect of captopril (50-100 mg/day) and verapamil (160-240 mg/day) on blood pressure, lung function and asthmatic sympto...

journal_title：Postgraduate medical journal

authors： Riska H,Stenius-Aaniala B,Sovijärvi AR

更新日期：1986-01-01 00:00:00

abstract：:We report a case of eosinophilic fasciitis, with the unusual features of pulmonary and pleural involvement. Similar cases which involve the lungs have been reported after exposure to L-tryptophan, but there is no relevant drug history in this case. ...

journal_title：Postgraduate medical journal

authors： Killen JW,Swift GL,White RJ

更新日期：2000-01-01 00:00:00

abstract：:A clinical and laboratory survey of systemic lupus erythematosus was conducted in 33 Arab patients in the UAE. Arthropathy (91%) followed by renal involvement (54%) and haematological disorders (45.5%) were the major clinical manifestations. Discoid rash (3%) was the least common. Apart from headaches, other neuropsyc...

journal_title：Postgraduate medical journal

authors： al-Attia HM

更新日期：1996-11-01 00:00:00

abstract：:We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient...

journal_title：Postgraduate medical journal

authors： Baruch Y,Ben-Arie Y,Kerner H,Lorber M,Best LA,Gershoni-Baruch R

更新日期：1991-04-01 00:00:00

abstract：:Two patients with nephrotic syndrome developed fatal fulminant hepatitis B following withdrawal of prednisolone or cyclophosphamide. Immunosuppressive therapy probably enhanced hepatitis B virus (HBV) replication and widespread infection of hepatocytes; its withdrawal permitted a return of immune competence resulting ...

journal_title：Postgraduate medical journal

authors： Onwubalili JK

更新日期：1988-04-01 00:00:00

abstract：:Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear. We report two patients with psoriatic arthritis and primary biliary cirrhosis respectively, who developed polymyositis while receiving D-penicillamine treatment for their primary diseases. Whet...

journal_title：Postgraduate medical journal

authors： Aydintug AO,Cervera R,D'Cruz D,Ramírez G,Asherson RA,Khamashta MA,Hughes GR

更新日期：1991-11-01 00:00:00

abstract：:Verrucous carcinoma is a rare skin malignancy of squamous cell origin. It is characterised by negligible cellular atypia and a low mitotic rate. These are reflected in slow locally invasive behaviour and very infrequent metastatic spread. The tumour is also recognised in oral and anogenital sites. Cutaneous lesions pr...

journal_title：Postgraduate medical journal

authors： Munro NA,Smith C,Purushotham AD

更新日期：1999-11-01 00:00:00

abstract：:The results of oesophago-gastro-duodenoscopy (OGD) and radiology in one hundred consecutive elderly patients were reviewed to assess the efficacy, safety and acceptability of endoscopy in this age group. False positive radiological features occurred in two of nine patients with normal endoscopic examinations. The rema...

journal_title：Postgraduate medical journal

authors： Stanley TV,Cocking JB

更新日期：1978-04-01 00:00:00

abstract：:Three patients with Crohn's disease are described who were treated by ileal resection for intestinal obstruction. Histological examination of the resected specimen in each case established the diagnosis of adenocarcinoma of the small intestine complicating Crohn's disease. This diagnosis should be considered in patien...

journal_title：Postgraduate medical journal

authors： Gillen CD,Wilson CA,Walmsley RS,Sanders DS,O'Dwyer ST,Allan RN

更新日期：1995-03-01 00:00:00

abstract：:Toxicity to digoxin was monitored in 437 consecutive recipients in a comprehensive drug surveillance programme, Adverse reactions developed in 19.5% and, in contrast to previous reports, were generally of a relatively benign nature. There were no drug-related deaths, but patients with adverse reactions spent longer in...

journal_title：Postgraduate medical journal

authors： Henry DA,Lowe JM,Lawson DA,Whiting B

更新日期：1981-06-01 00:00:00

abstract：:Treatment of angina with a single drug often proves unsatisfactory because of dose-related unwanted effects or occasionally an adverse effect on the angina. A combination of a beta-blocking agent and a calcium antagonist drug might achieve satisfactory control of angina at acceptable doses of each drug. Widespread app...

journal_title：Postgraduate medical journal

authors： Geddes JS

更新日期：1983-01-01 00:00:00

abstract：:Infection with hepatitis B virus (HBV) is much more common in tropical than in temperate countries. Visitors to the tropics are thus at risk from HBV, though the degree of risk, and the routes of infection involved are uncertain. We report serological markers of HBV in two groups of 2nd World War soldiers, who served ...

journal_title：Postgraduate medical journal

authors： Gill GV,Bell DR,Vandervelde EM

更新日期：1991-01-01 00:00:00

abstract：:Functional metastatic adrenocortical carcinoma is an uncommon cause of Cushing's syndrome, which rarely responds to conventional treatment. A patient presenting with Cushing's syndrome secondary to adrenocortical carcinoma underwent surgical resection. Postoperatively, she developed metastatic disease resistant to con...

journal_title：Postgraduate medical journal

authors： Chan NN,Isaacs AJ

更新日期：1999-02-01 00:00:00

abstract：:A 17 year old woman presented with severe anaemia due to menorrhagia. On investigation, she was shown to have abnormalities of her haemostatic mechanism consistent with von Willebrand's disease Type I, although there was no family history of this disorder. In addition, she was shown to have severe primary hypothyroidi...

journal_title：Postgraduate medical journal

authors： Blesing NE,Hambley H,McDonald GA

更新日期：1990-06-01 00:00:00