Fulminant hepatic failure in nephrotic syndrome related to withdrawal of immunosuppressive therapy.

abstract：:Digoxin has been a key therapeutic for heart failure and atrial tachyarrhythmias for over 200 years following Withering's groundbreaking work depicting the therapeutic benefit of the common botanical foxglove in his 1785 monograph. The use of digoxin preceded any randomised evidence or even basic understanding of its ...

journal_title：Postgraduate medical journal

authors： Stucky MA,Goldberger ZD

更新日期：2015-09-01 00:00:00

abstract：:A patient with Laurence-Moon-Biedl syndrome and nephrotic range proteinuria is presented. Radiological investigation of the urinary tract revealed clubbed calyces but no evidence of obstruction or vesicoureteric reflux. Renal biopsy revealed occasional sclerotic glomeruli, extensive foot-process fusion and segmental g...

journal_title：Postgraduate medical journal

authors： Cheng IK,Chan KW,Chan MK,Kung A,Ma J,Wang C

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Randomised controlled trials (RCTs) have shown that endoscopic haemostasis is beneficial for patients with a bleeding peptic ulcer. The relevance of such data to management outside of RCTs is unclear. Therefore we examined management of patients with a bleeding peptic ulcer in a UK teaching hospital. METHOD...

journal_title：Postgraduate medical journal

authors： Mahadeva S,Linch M,Hull MA

更新日期：2002-06-01 00:00:00

abstract：:Aspirin was first synthesised 100 years ago and its preparation and marketing is generally reckoned to have been the foundation of the pharmaceutical industry. For most of the time since then it has been used for the relief of pain and fever. The modern phase of aspirin use commenced with the reporting in 1974 of a ra...

journal_title：Postgraduate medical journal

authors： Elwood PC,Hughes C,O'Brien JR

更新日期：1998-10-01 00:00:00

abstract：:Metabolic acidosis and hyperlactataemia are important, independent findings in acute illness, and the combination of these abnormalities carries a grave prognosis. Despite this there is still controversy about the most appropriate therapy of lactic acidosis, and the relationship of commonly used acid base measurements...

journal_title：Postgraduate medical journal

authors： Nimmo GR,Grant IS,Mackenzie SJ

更新日期：1991-01-01 00:00:00

abstract：:Liver transplantation is the accepted treatment for a wide variety of liver diseases in children. Over the past 10 years a number of innovative surgical techniques have been developed to overcome the shortage of size matched donors particularly in children less than 5 years of age. Graft and patient survival at one ye...

journal_title：Postgraduate medical journal

authors： Vilca-Melendez H,Heaton ND

更新日期：2004-10-01 00:00:00

abstract：:A 19-year-old girl developed generalised anhidrosis following typhoid fever. Elaborate investigations disclosed nothing abnormal. A skin biopsy revealed the presence of atrophic as well as normal eccrine glands. This appears to be the third case of its kind in the English literature. It is postulated that typhoid feve...

journal_title：Postgraduate medical journal

authors： Raveenthiran V

更新日期：1995-07-01 00:00:00

abstract：:Some antifungal agents have been tested qualitatively in various associations against species of Candida, Cryptococcus and Torulopsis. The method used was the channel test and the results are confirmed by comparison with the serial dilution test in agar. The antagonism in vitro with the combination of amphotericin B i...

journal_title：Postgraduate medical journal

authors： Dupont B,Drouhet E

更新日期：1979-09-01 00:00:00

abstract：:Ulcerative colitis is not commonly associated with recognizable pulmonary disease and only four sporadic cases of sarcoidosis in association with ulcerative colitis have been previously reported. However, in a series of 680 patients with ulcerative colitis, pulmonary or extra-pulmonary sarcoidosis has at some stage be...

journal_title：Postgraduate medical journal

authors： Barr GD,Shale DJ,Jewell DP

更新日期：1986-05-01 00:00:00

abstract：:Fasting plasma and urinary calcium and urinary hydroxyproline are known to rise at the menopause, reflecting increased bone resorption. Oestradiol valerate and cyclic oestradiol valerate/DL-norgestrel are shown to reduce this evidence of increased bone loss. It is concluded that these preparations will be effective in...

journal_title：Postgraduate medical journal

authors： Crilly RG,Marshall DH,Nordin BE

更新日期：1978-01-01 00:00:00

abstract：:Following the drinking of 150 g of alcohol and a large amount of intra-nasal cocaine a previously healthy 31 year old man developed severe retrosternal pain and circulatory failure. An electrocardiogram showed supra-ventricular tachycardia with widespread ischaemic changes. Following electrical cardioversion electroca...

journal_title：Postgraduate medical journal

authors： Boag F,Havard CW

更新日期：1985-11-01 00:00:00

abstract：:Although contrast angiography is important in the diagnosis and treatment of atherosclerotic disease, it does have limitations. Intracoronary ultrasound more accurately assesses the amount of atherosclerosis and has given us new insights into the pathophysiology of coronary plaque accumulation and remodelling. It also...

journal_title：Postgraduate medical journal

authors： Hammond C,Causer JP,Perry RA

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To determine changes in hepatitis B virus (HBV) prevalence across three different time periods in pregnant women. METHODS:This was a retrospective study of pregnant women attending four healthcare centres between January 1995 and May 2015. Data for serum hepatitis B surface antigen (HBsAg) and anti-HBs level...

journal_title：Postgraduate medical journal

authors： Furuncuoglu Y,Bolukbas FF,Bolukbas C,Torun P,Ozturk R

更新日期：2016-09-01 00:00:00

abstract：:Colonoscopies performed in patients aged 80 years or older at the Sheba Medical Center were analysed according to the primary indication for the procedure: 101 colonoscopies were performed because of rectal bleeding of at least 2 months duration, and 335 for all other indications. Carcinoma of the large bowel was foun...

journal_title：Postgraduate medical journal

authors： Bat L,Pines A,Shemesh E,Levo Y,Zeeli D,Scapa E,Rosenblum Y

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Primary percutaneous coronary intervention (PPCI) programmes vary in admission criteria from open referral to acceptance of electrocardiogram (ECG) protocol positive patients only. Rigid criteria may result in some patients with acutely occluded coronary arteries not receiving timely reperfusion therapy. OB...

journal_title：Postgraduate medical journal

authors： Apps A,Malhotra A,Tarkin J,Smith R,Kabir T,Lane R,Mason M,Ali O,Rogers P,Banya W,Whitbread M,Ilsley C,Dalby M

更新日期：2013-07-01 00:00:00

abstract：:The factors related to the occurrence of bacteraemia following urinary tract manipulation were studied in a large community hospital. During a 3-year period, forty-six of 326 episodes of hospital-acquired bacteraemia were associated with urinary tract manipulation. All thirty of forty-six cases felt to be definitely r...

journal_title：Postgraduate medical journal

authors： Quintiliani R,Klimek J,Cunha BA,Maderazo EG

更新日期：1978-10-01 00:00:00

abstract：:In the 1920s Moynihan described acute pancreatitis as "..the most terrible of all intra-abdominal calamities". He established a practice of immediate surgical intervention to remove the toxic products accumulating in the peritoneal cavity, and this treatment was endorsed by most centres, remaining the standard therapy...

journal_title：Postgraduate medical journal

authors： Skaife P,Kingsnorth AN

更新日期：1996-05-01 00:00:00

abstract：:Four cases of severe osteolysis of bones subsequent to camel bite are described. The first had osteolysis of the ribs with traumatic diaphragmatic hernia. Two cases had similar appearances of gross osteolysis of the shafts of the radius and ulna, whilst one had osteolysis of the humeral shaft. The similarities in the ...

journal_title：Postgraduate medical journal

authors： al-Boukai AA,Hawass NE,Patel PJ,Kolawole TM

更新日期：1989-12-01 00:00:00

abstract：:Exercise is known to have a vast array of health benefits. It may however confer delirious effects on most body systems, with the cardiovascular system taking particular prominence. Athletes in particular are known to be at a higher risk for sudden cardiac death as a result of several cardiac adaptations which take pl...

journal_title：Postgraduate medical journal

authors： Abela M,Sammut L

更新日期：2017-12-01 00:00:00

abstract：:The development of clinical governance in New Zealand has been pivotal to the country's health policy since 2009. Some of the key findings from one component of a national assessment project, which involved interviews with health professionals and managers at 19 of the country's 20 district health boards, are reviewed...

journal_title：Postgraduate medical journal

authors： Gauld R

更新日期：2014-01-01 00:00:00

abstract：:The majority of deaths in COPD are from cardiovascular causes. Several large randomized controlled trials demonstrate that inhaled anticholinergic agents ipratropium and tiotropium increase the risk of serious cardiovascular events, including cardiovascular mortality. Tiotropium Respimat is associated with a statistic...

journal_title：Postgraduate medical journal

authors： Singh S,Loke YK,Enright P,Furberg CD

更新日期：2014-04-01 00:00:00

abstract：:Two hundred and thirty-three patients with renal amyloidosis were studied in an attempt to identify the incidence and pattern of the disease in northern India. The incidence of amyloidosis was 1.01% of 6431 post-mortems and 8.4% of 1980 renal biopsies from patients who presented with clinical evidence of glomerular di...

journal_title：Postgraduate medical journal

authors： Chugh KS,Datta BN,Singhal PC,Jain SK,Sakhuja V,Dash SC

更新日期：1981-01-01 00:00:00

abstract：:A previously healthy 17 year old boy had Staphylococcus aureus endocarditis presenting as acute scrotal pain. There was no trauma or evidence of scrotal or epididymal infection. The pain subsided after therapy for endocarditis was started. ...

journal_title：Postgraduate medical journal

authors： Watanakunakorn C

更新日期：1987-07-01 00:00:00

abstract：:Prospective measurements of serum thyrotrophin and thyroxine concentrations were made in six patients with primary hypothyroidism treated consecutively with an incremental regimen of oral thyroxine. A fall in thyrotrophin occurred over several months, accompanied by a concurrent slow rise in serum thyroxine. Those pat...

journal_title：Postgraduate medical journal

authors： Ghose RR,Upadhyay HP

更新日期：1986-01-01 00:00:00

abstract：:A previously fit man developed psittacosis with marked cerebellar symptoms and signs. He was febrile but not confused, and he responded rapidly to treatment with erythromycin. Even if respiratory symptoms are minimal, psittacosis and other atypical pneumonias should be considered in any patient presenting with fever a...

journal_title：Postgraduate medical journal

authors： Shee CD

更新日期：1988-05-01 00:00:00

abstract：:Quantitative lipoprotein level data was obtained from healthy subjects and patients with ischaemic heart disease or peripheral vascular disease in four European communities. Hypertriglyceridaemia, due mainly to an increase in VLDL triglyceride, was commoner in London and Uppsala than in Naples and Geneva. In three com...

journal_title：Postgraduate medical journal

authors： Lewis B,Carlson LA,Mancini M,Micheli H

更新日期：1975-01-01 00:00:00

abstract：:In 93 patients with hypertension uncontrolled by bendrofluazide 5 mg plus atenolol 100 mg daily, the effects of adding nifedipine (up to 60 mg/day, n = 31), prazosin (up to 20 mg/day, n = 31), or hydralazine (up to 200 mg/day, n = 31) were compared in a 6 month open random parallel group study. The three drugs did not...

journal_title：Postgraduate medical journal

authors： Ramsay LE,Parnell L,Waller PC

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Asthma, a common childhood condition, often presents with chronic cough. While evaluating for chronic cough, many specialists obtain a baseline chest radiograph (CR) to assess for other causes. Usually read as 'normal', sometimes CRs will reveal evidence of airway inflammation in the form of subtle findings,...

journal_title：Postgraduate medical journal

authors： Abeles M,Akerman M,Halaby C,Pirzada M

更新日期：2020-12-03 00:00:00

abstract：:The effect of captopril monotherapy on blood pressure and metabolism was investigated in a placebo-controlled study in 30 non-insulin dependent (Type II) diabetic subjects during a 3-week observation period (run-in/drug; placebo/wash-out) on a metabolic ward. Captopril significantly reduced both systolic and diastolic...

journal_title：Postgraduate medical journal

authors： Rett K,Wicklmayr M,Tschollar W,Dietze G,Mehnert H

更新日期：1988-01-01 00:00:00

abstract：:This paper reports a clinical study of 20 cases of gangrenous ulcers of the scrotum and/or of the penis (Fournier's gangrene) and a review of previous publications. Even though found mostly in elderly male patients, the disease spares no age group and can involve the external genitalia in neonates and women as well. T...

journal_title：Postgraduate medical journal

authors： Efem SE

更新日期：1994-08-01 00:00:00