Glomerulonephropathy of Laurence-Moon-Biedl syndrome.

Abstract:

:A patient with Laurence-Moon-Biedl syndrome and nephrotic range proteinuria is presented. Radiological investigation of the urinary tract revealed clubbed calyces but no evidence of obstruction or vesicoureteric reflux. Renal biopsy revealed occasional sclerotic glomeruli, extensive foot-process fusion and segmental glomerular basement membrane abnormalities with negative immunofluorescence for immunoglobulins and complement. Nephrotic proteinuria responded to steroid therapy but mild proteinuria persisted. The findings were consistent with minimal change nephropathy superimposed on the glomerular lesions of Lawrence-Moon-Biedl syndrome.

journal_name

Postgrad Med J

authors

Cheng IK,Chan KW,Chan MK,Kung A,Ma J,Wang C

doi

10.1136/pgmj.64.754.621

subject

Has Abstract

pub_date

1988-08-01 00:00:00

pages

621-5

issue

754

eissn

0032-5473

issn

1469-0756

journal_volume

64

pub_type

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