Detection of hepatic encephalopathy.

Abstract:

:The most sensitive index of hepatic encephalopathy in 29 patients following a porta-caval shunt appeared to be the assessment of a close relative who had known the patient pre-operatively. They noticed that 19 of the 20 patients were mentally slower; 11 were markedly aggressive and 8 had become placid and uncaring about family problems. Only 9 of these patients had clinical encephalopathy as judged by two independent observers, 14 had a prolonged trail test and 8 produced an abnormal five-pointed star. Eight patients were forced to retire prematurely after the operation due to ill health and 20 felt that their marriage had deteriorated. Eighteen of the 29 patients had a lie score on the Eysenck personality questionnaire (an index of 'social naïvety') which was more than one standard deviation above the mean value for a large control group (P less than 0.01). This did not correlate with other measurements of encephalopathy, but 8 out of the 11 patients who exhibited aggressive behaviour had an abnormal score.

journal_name

Postgrad Med J

authors

Gazzard BG,Price H,Dawson AM

doi

10.1136/pgmj.62.725.163

subject

Has Abstract

pub_date

1986-03-01 00:00:00

pages

163-6

issue

725

eissn

0032-5473

issn

1469-0756

journal_volume

62

pub_type

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