How late is too late and how early is early: the clinician's view of the first 100 minutes.

abstract：:We report what we believe is the first recorded case of Mondor's disease associated with metastatic lung cancer presenting in the breast. An association between Mondor's disease and primary breast cancer has been described previously. In patients with Mondor's disease and primary breast cancer has been described previ...

journal_title：Postgraduate medical journal

authors： Courtney SP,Polacarz S,Raftery AT

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Audience response systems (ARSs) are electronic devices that allow educators to pose questions during lectures and receive immediate feedback on student knowledge. The current literature on the effectiveness of ARSs is contradictory, and their impact on student learning remains unclear. OBJECTIVES:This rand...

journal_title：Postgraduate medical journal

authors： Mains TE,Cofrancesco J Jr,Milner SM,Shah NG,Goldberg H

更新日期：2015-07-01 00:00:00

abstract：:Salivary gland lymphoma is associated with Sjögren's syndrome. A case of bilateral submandibular gland and sublingual gland lymphoma, arising in Sjögren's syndrome, is presented. A lymphoma involving more than one salivary gland may occur in Sjögren's syndrome, and there is an increased risk of developing an extrasali...

journal_title：Postgraduate medical journal

authors： Law NW,Leader M

更新日期：1987-02-01 00:00:00

abstract：:A 75 year old woman was treated for over three years with the somatostatin analogue, octreotide for an insulinoma. She had presented in a hypoglycaemic coma. C-peptide and insulin concentrations were both raised and an area of increased vascularity within the pancreas was shown by angiography. No lesion was found at l...

journal_title：Postgraduate medical journal

authors： Craig CE,Gallen IW

更新日期：2002-10-01 00:00:00

abstract：:Antenatal appendicular perforation leading to localized meconium peritonitis and intestinal obstruction is reported in a premature neonate. The baby was successfully treated by a limited ileocaecal resection. ...

journal_title：Postgraduate medical journal

authors： Narasimharao KL,Mitra SK,Pathak IC

更新日期：1987-11-01 00:00:00

abstract：:It was considered that the first dose reaction occurring with prazosin may have been due either to hypotension or to a specific reduction in cerebral blood flow. The development of a quantitative non-invasion nuclear medicine technique for cerebral flow has now made it possible to investigate the effects of prazosin o...

journal_title：Postgraduate medical journal

authors： Rutland MD,Lee TY,Nimmon CC,Granowska M,Britton KE

更新日期：1980-12-01 00:00:00

abstract：:The causes of death, as determined by autopsy, in 10 patients dying from the acute effects of phaeochromocytoma were myocardial infarction (five patients), left ventricular failure (two patients), cerebral haemorrhage (two patients) and circulatory collapse with malignant phaeochromocytoma (one patient). Most patients...

journal_title：Postgraduate medical journal

authors： Cohen CD,Dent DM

更新日期：1984-02-01 00:00:00

abstract：:The in vitro activity of cefaclor was compared with that of cephalexin and cephradine. This new antibiotic was the most active of the oral agents against Haemophilus influenzae (especially non-beta-lactamase producing strains). It was also significantly more active against N. gonorrhoeae and the Enterobacteriaceae. Th...

journal_title：Postgraduate medical journal

authors： Gillett AP,Andrews JM,Wise R

更新日期：1979-01-01 00:00:00

abstract：:The mechanisms of the antinociceptive action of flupirtine, a novel non-opioid analgesic, were investigated in animals. It was found that this effect could be abolished by pre-treatment with reserpine. Furthermore, it could be dose-dependently antagonized by yohimbine and changes in the EEG of the rat observed after a...

journal_title：Postgraduate medical journal

authors： Szelenyi I,Nickel B

更新日期：1987-01-01 00:00:00

abstract：:A study has been made in rodents of the interactions between a range of psychotropic drugs, narcotic agonist and partial agonist analgesics, and pain. In rodents, tricyclic antidepressants do not alone reduce pain responses but, in combination with morphine or pentazocine, clomipramine enhances analgesic activity afte...

journal_title：Postgraduate medical journal

authors： Lee RL,Spencer PS

更新日期：1980-01-01 00:00:00

abstract：:We report the case of a 58 year old man in whom an unusually prolonged infection with Toxoplasma gondii was the presenting feature of an underlying non-Hodgkin's lymphoma. This case demonstrates the particular usefulness of the IgM ELISA test in monitoring disease activity. ...

journal_title：Postgraduate medical journal

authors： Dudley NJ,Balfour AH

更新日期：1988-11-01 00:00:00

abstract：:A 68 year old man developed cranial diabetes insipidus 3 years after the diagnosis of myelofibrosis, coincident with a marked increase in nucleated cell count. No mass lesion was demonstrable on computed tomographic or magnetic resonance imaging. It is suggested that hypothalamic damage was caused by local infiltratio...

journal_title：Postgraduate medical journal

authors： Dornan TL,Gillett G,Jones PA,Jeffcoate WJ

更新日期：1989-01-01 00:00:00

abstract：:Two patients with severe dothiepin intoxication are described. The management of these cases is discussed and we draw attention to the prolonged elimination half-life of dothiepin and its metabolites, and the implication for treatment. ...

journal_title：Postgraduate medical journal

authors： Bloodworth L,Wilson A,Collins P,Rainford DJ

更新日期：1984-06-01 00:00:00

abstract：:Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical ...

journal_title：Postgraduate medical journal

authors： Mahy IR,Jennings KP

更新日期：1998-06-01 00:00:00

abstract：:Thirty-one patients with radiolucent common bile duct stones received medical treatment. Nineteen had Rowachol, a terpene preparation, eight (42%) achieving complete stone disappearance within 3 to 48 months. Fifteen (including 3 of the above) took Rowachol with bile acid (chenodeoxycholic in 11, ursodeoxycholic in 4)...

journal_title：Postgraduate medical journal

authors： Somerville KW,Ellis WR,Whitten BH,Balfour TW,Bell GD

更新日期：1985-04-01 00:00:00

abstract：:We describe two patients with associations of hereditary neuropathies and heritable skeletal disorders not previously reported. The first patient had Marfan's syndrome and hereditary motor and sensory neuropathy Type 1. The second patient had Ehlers-Danlos syndrome, Klippel-Feil syndrome and tomaculous neuropathy. ...

journal_title：Postgraduate medical journal

authors： Chattopadhyay AK,Kandler RH,Sharrack B

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:To determine changes in hepatitis B virus (HBV) prevalence across three different time periods in pregnant women. METHODS:This was a retrospective study of pregnant women attending four healthcare centres between January 1995 and May 2015. Data for serum hepatitis B surface antigen (HBsAg) and anti-HBs level...

journal_title：Postgraduate medical journal

authors： Furuncuoglu Y,Bolukbas FF,Bolukbas C,Torun P,Ozturk R

更新日期：2016-09-01 00:00:00

abstract：:Forty-five healthy men aged 21-34 years took part in a double-blind, parallel-group, placebo-controlled study of the effects of 28 days' treatment with lornoxicam 4 mg twice daily or indomethacin 50 mg twice daily on faecal blood loss and the endoscopic appearances of gastric and duodenal mucosa. After an initial endo...

journal_title：Postgraduate medical journal

authors： Warrington SJ,Debbas NM,Farthing M,Horton M,Johnston A,Thillainayagam A,Turner P,Ferber H

更新日期：1990-08-01 00:00:00

abstract：:Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage as defined by the UICC-TNM and American Joint Committee on Cancer classifications. Tumour extent, lymph node status, tumour grade and the assessment of lymphatic and venous invasion are still the most important morphological progn...

journal_title：Postgraduate medical journal

authors： Zlobec I,Lugli A

更新日期：2008-08-01 00:00:00

abstract：:Gastric outlet obstruction by gall stone is a rare complication of a common disorder. Two cases are reported here. The investigations are conducted along the same lines as for pyloric stenosis. The diagnosis can be made with a barium meal or gastroscopy. Treatment is by surgical intervention after adequate resuscitati...

journal_title：Postgraduate medical journal

authors： Ah-Chong K,Leong YP

更新日期：1987-10-01 00:00:00

abstract：:Important implications for the recognition of iron deficiency anaemia include diagnosis and correction of underlying causes, most of which are identifiable, in the older patient, by means of conventional upper gastrointestinal endoscopy, and by colonoscopy. The aetiological search may, however, have to be widened to i...

journal_title：Postgraduate medical journal

authors： Jolobe OM

更新日期：2000-04-01 00:00:00

abstract：:A case of skin necrosis at the sites of injection of subcutaneous heparin is described. The patient went on to develop heparin-induced thrombocytopenia and pulmonary embolism. Review of the previously described cases of heparin-associated skin necrosis reveals that this sequence of events is not uncommon. ...

journal_title：Postgraduate medical journal

authors： Fowlie J,Stanton PD,Anderson JR

更新日期：1990-07-01 00:00:00

abstract：:Colonic strictures are very common and are a frequent finding on double contrast barium examination; they very often reflect the presence of malignancy, diverticular disease, ischaemia, inflammatory bowel disease, and rarely mycobacterial disease. A case of mycobacterial disease mimicking malignancy is presented; this...

journal_title：Postgraduate medical journal

authors： Rees JR,Longstaff A,Rigby HL,Smith DL,Dixon AR

更新日期：2003-12-01 00:00:00

abstract：:The healthcare industry has seen an increase in the adoption of team training, such as crew resource management (CRM), to improve teamwork and coordination within acute care medical teams. A meta-analysis was carried out in order to quantify the effects of CRM training on reactions, learning, behaviour and clinical ca...

journal_title：Postgraduate medical journal

authors： O'Dea A,O'Connor P,Keogh I

更新日期：2014-12-01 00:00:00

abstract：:Although an extensive literature exists on factors controlling sodium excretion in animal experimental models of heart failure, the relevance of these to the human condition remains largely unexplored. Increased renal sympathetic stimulation is considered responsible for heightened urinary sodium retention. Stimulatio...

journal_title：Postgraduate medical journal

authors： Good J,Frost G,Oakley CM,Cleland JG

更新日期：1992-01-01 00:00:00

abstract：:In a cross-over study, 10 healthy adult volunteers received 1 g cefaclor and 1 g cephalexin orally 1 hour after a standard breakfast. Serum levels of cefaclor rose somewhat faster and were higher than those of cephalexin in the first 60 minutes. At the end of the second hour the serum concentration of cephalexin was 5...

journal_title：Postgraduate medical journal

authors： Simon C,Gatzemeier U

更新日期：1979-01-01 00:00:00

abstract：:This study assesses the economic benefits of misoprostol in the prophylaxis of gastric ulcers larger than 0.3 cm in patients with osteoarthritis receiving non-steroidal anti-inflammatory drugs. Independent epidemiological data were obtained for patients in Scotland and the West Midlands. Co-diagnosis of arthritis with...

journal_title：Postgraduate medical journal

authors： Knill-Jones R,Drummond M,Kohli H,Davies L

更新日期：1990-08-01 00:00:00

abstract：:The most sensitive index of hepatic encephalopathy in 29 patients following a porta-caval shunt appeared to be the assessment of a close relative who had known the patient pre-operatively. They noticed that 19 of the 20 patients were mentally slower; 11 were markedly aggressive and 8 had become placid and uncaring abo...

journal_title：Postgraduate medical journal

authors： Gazzard BG,Price H,Dawson AM

更新日期：1986-03-01 00:00:00

abstract：:A 5-year-old girl presented with a swelling in the right axilla from which Mycobacterium avium-intracellulare was cultured. The gland was excised and she made an uneventful recovery. ...

journal_title：Postgraduate medical journal

authors： Colley EW,Cox RA

更新日期：1983-09-01 00:00:00

abstract：:A patient with calcific constrictive pericarditis due to rheumatoid arthritis is presented: the literature reveals only one previous case which was attributed to the long duration of the rheumatoid arthritis. ...

journal_title：Postgraduate medical journal

authors： Manji H,Raven P

更新日期：1990-01-01 00:00:00