Comparative in vitro microbiological activity and stability of cefaclor.

Abstract:

:The in vitro activity of cefaclor was compared with that of cephalexin and cephradine. This new antibiotic was the most active of the oral agents against Haemophilus influenzae (especially non-beta-lactamase producing strains). It was also significantly more active against N. gonorrhoeae and the Enterobacteriaceae. The instability in agar raises some issues that need further study.

journal_name

Postgrad Med J

authors

Gillett AP,Andrews JM,Wise R

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

9-11

eissn

0032-5473

issn

1469-0756

journal_volume

55 Suppl 4

pub_type

杂志文章
  • Spinal reconstruction for symptomatic thoracic haemangioma using a titanium cage.

    abstract::Most vertebral haemangiomas are asymptomatic. A case of spinal reconstruction for symptomatic extraosseous thoracic haemangioma using a titanium cage is reported. Radiographs of the T11 vertebra demonstrated characteristic vertical striations. Magnetic resonance imaging and computed tomography showed spinal cord compr...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pmj.78.923.559

    authors: Ogura T,Mori M,Hayashida T,Osawa T,Hase H

    更新日期:2002-09-01 00:00:00

  • Unravelling the helix--a physician's guide to spiral computed tomography.

    abstract::The introduction of spiral technology to computed tomography (CT) scanners in the late 1980s has revolutionised the field of CT. Spiral CT offers definite practical benefits over conventional scanners and has expanded the role of CT through the development of new scanning techniques. CT scanning now rivals magnetic re...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.74.868.96

    authors: Kearney SE,Garvey CJ

    更新日期:1998-02-01 00:00:00

  • Association between circulating leptin levels and multiple sclerosis: a systematic review and meta-analysis.

    abstract:AIM:Leptin, synthesised by adipocytes, has been identified as a hormone that can influence inflammatory activity. Several studies have investigated leptin levels in patients with multiple sclerosis (MS), but the results are not consistent. This study aims to derive a more precise evaluation on the relationship between ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1136/postgradmedj-2017-135397

    authors: Xie XF,Huang XH,Shen AZ,Li J,Sun YH

    更新日期:2018-05-01 00:00:00

  • Effect of prostaglandin E1 on deposition of autologous labelled platelets onto human atherosclerotic lesions in vivo.

    abstract::The effects of infusions of prostaglandin E1 (PGE1) on platelet deposition at atherosclerotic sites in vivo in man have been examined. Thirteen patients with atherosclerotic vascular disease received intravenous PGE1 25 mg/kg/min for 6 hours daily for 5 days. Prostaglandin E1 had no effect on platelet uptake at athero...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.63.738.245

    authors: Sinzinger H,O'Grady J,Fitscha P

    更新日期:1987-04-01 00:00:00

  • Prospective study of acute gastrointestinal bleeding attributable to anti-inflammatory drug ingestion in the Yorkshire region of the United Kingdom.

    abstract:OBJECTIVE:To assess the general use of all non-steroidal anti-inflammatory drugs (NSAID) and their relation to upper gastrointestinal bleeding in view of National Institute for Clinical Excellence guidelines published in July 2001 in the UK. METHODS:Cross sectional study on all patients who were referred for endoscopy...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,多中心研究

    doi:10.1136/pgmj.2004.024885

    authors: Lim CH,Heatley RV

    更新日期:2005-04-01 00:00:00

  • Prevalence and characteristics in coding, classification and diagnosis of diabetes in primary care.

    abstract:INTRODUCTION:Approximately 366 million people worldwide live with diabetes and this figure is expected to rise. Among the correct diagnosis, there will be errors in the diagnosis, classification and coding, resulting in adverse health and financial implications. AIM:To determine the prevalence and characteristics of d...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,多中心研究

    doi:10.1136/postgradmedj-2013-132068

    authors: Seidu S,Davies MJ,Mostafa S,de Lusignan S,Khunti K

    更新日期:2014-01-01 00:00:00

  • Recurrent sub-mucosal dissection of the oesophagus in association with achalasia.

    abstract::Submucosal dissection of the oesophagus is a rare oesophageal disorder. We report a patient who had recurrent episodes of dissection and achalasia. Both recurrence and the association with achalasia are to our knowledge unique. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.732.955

    authors: Hooper TL,Gholkar J,Smith SR,Manns JJ,Moussalli H

    更新日期:1986-10-01 00:00:00

  • Acute barium intoxication following ingestion of ceramic glaze.

    abstract::A case of deliberate overdose of barium sulphide in a psychiatric setting is presented, with resulting flaccid paralysis, malignant arrhythmia, respiratory arrest and severe hypokalaemia, but ultimately with complete recovery. The degree of paralysis appears to be related directly to serum barium levels. The value of ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.74.875.545

    authors: Thomas M,Bowie D,Walker R

    更新日期:1998-09-01 00:00:00

  • Caring for "incurables": the 150th anniversary of the Royal Hospital for Neuro-Disability, Putney.

    abstract::The Royal Hospital for Incurables (RHI), now known as the Royal Hospital for Neuro-Disability and situated on West Hill, Putney, was founded by Andrew Reed DD exactly 150 years ago. The RHI was thus the pioneer in modern times of long stay institutions for the sick and dying. It became one of the great Victorian chari...

    journal_title:Postgraduate medical journal

    pub_type: 历史文章,杂志文章

    doi:10.1136/pgmj.2003.017673

    authors: Cook GC

    更新日期:2004-07-01 00:00:00

  • Prognostic factors in Wegener's granulomatosis.

    abstract::We analysed data from 64 patients with Wegener's granulomatosis to determine predictor variables of outcome. The mean period of observation after the diagnosis had been established was 3.2 (range 0.1-11.2) years. At the time of diagnosis, 15 (23%) patients had only local symptoms. The disease was generalized to multip...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.69.817.856

    authors: Briedigkeit L,Kettritz R,Göbel U,Natusch R

    更新日期:1993-11-01 00:00:00

  • Cyclical release of vasoactive intestinal polypeptide (VIP) from a pancreatic islet cell apudoma.

    abstract::A patient is described who presented with the classical symptomatology and profound electrolyte disturbance of the Verner-Morrison syndrome due to a pancreatic apudoma secreting vasoactive intestinal polypeptide (VIP). Diagnosis was confirmed by plasma VIP as measured by a radio-immunoassay technique now available. It...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.54.634.566

    authors: Devine BL,Carmichael HA,Russell RI,Joffe SN

    更新日期:1978-08-01 00:00:00

  • Rectal bleeding in the first month of life.

    abstract::Sixty-nine infants were examined who presented with rectal bleeding in the first month of life. In 64% of these children no cause was found. Infantile diarrhoea, haemorrhagic disease of the newborn and anal fissure were the most common diagnoses made. The mortality in the entire group was less than 3%. It is concluded...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.55.639.22

    authors: Levene MI

    更新日期:1979-01-01 00:00:00

  • Closure of traumatic wounds without cleaning and suturing.

    abstract:BACKGROUND:In less than ideal situations wounds have to be closed without extensive cleaning using sterile adhesive strips (Steristrips). This prospective analyses the efficiency of this technique and compares it to the more conventional approach. METHODS:Altogether 147 lacerations were closed with sterile strips with...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pmj.78.919.281

    authors: Maharaj D,Sharma D,Ramdass M,Naraynsingh V

    更新日期:2002-05-01 00:00:00

  • Acute pancreatitis and Cushing's syndrome.

    abstract::A case of acute necrotizing pancreatitis in a 53-year-old man with an ectopic adrenocorticotrophin (ACTH) producing bronchial carcinoma is described. The aetiology of acute pancreatitis in relation to steroid therapy and malignancy is discussed and it is suggested that excess endogenous steroid production may also cau...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.60.707.618

    authors: Clague HW,Warren B,Krasner N

    更新日期:1984-09-01 00:00:00

  • Changes in the prevalence of HBV infection in pregnant women in Turkey between 1995 and 2015: a 20-year evaluation.

    abstract:OBJECTIVE:To determine changes in hepatitis B virus (HBV) prevalence across three different time periods in pregnant women. METHODS:This was a retrospective study of pregnant women attending four healthcare centres between January 1995 and May 2015. Data for serum hepatitis B surface antigen (HBsAg) and anti-HBs level...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2015-133876

    authors: Furuncuoglu Y,Bolukbas FF,Bolukbas C,Torun P,Ozturk R

    更新日期:2016-09-01 00:00:00

  • Carotid sinus syndrome after carotid artery surgery.

    abstract::A 63 year old woman had been intensively treated for recurrent carcinoma of the neck. Following acute vascular surgery of the carotid artery, she developed the vasodilatory type of the carotid sinus syndrome. The presentation of this type of the syndrome was remarkable, since it is usually associated with primary or m...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.68.800.463

    authors: Dees A,Baatenburg de Jong RJ,Meeuwis CA,de Boer MF,de Leeuw PW

    更新日期:1992-06-01 00:00:00

  • Chronic kidney disease presenting acutely: presentation, clinical features and outcome of patients with irreversible chronic kidney disease who require dialysis immediately.

    abstract:BACKGROUND:Patients with irreversible chronic kidney disease who require dialysis immediately are a subset of ultra late referrals for whom the term chronic kidney disease presenting acutely might usefully be applied. Although well known to nephrologists and recognised as a specific group with considerable problems, li...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2009.078956

    authors: Wolfe M,Almond A,Robertson S,Donaldson K,Isles C

    更新日期:2010-07-01 00:00:00

  • Optimising clinical performance during resuscitation using video evaluation.

    abstract::Video evaluation of resuscitation is becoming increasingly integrated into practice in a number of clinical settings. The purpose of this review article is to examine how video may enhance clinical care during resuscitation. As healthcare and available therapeutic interventions evolve, re-evaluation of accepted paradi...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/postgradmedj-2016-134357

    authors: Lowe DJ,Dewar A,Lloyd A,Edgar S,Clegg GR

    更新日期:2017-08-01 00:00:00

  • Lessons from falling coronary heart disease mortality in the United States.

    abstract::The marked decline in coronary heart disease mortality in the United States since the late 1960s is most likely due in large part to successful efforts at primary prevention, attributable in turn to improved eating habits, better control of blood pressure and a reduction in smoking. Another part of the decline can pro...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.60.699.15

    authors: Epstein FH

    更新日期:1984-01-01 00:00:00

  • Diurnal rhythms and clinical events in coronary artery disease.

    abstract::Patients with coronary atherosclerosis present with angina, myocardial infarction and sudden death, most often caused by atherosclerotic stenosis complicated by spasm and/or occlusive thrombosis. All of these events have been shown to exhibit similar diurnal rhythms, with a peak incidence in the morning after waking a...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Selwyn AP,Raby K,Vita JA,Ganz P,Yeung A

    更新日期:1991-01-01 00:00:00

  • Hospital-acquired serum phosphate derangements and their associated in-hospital mortality.

    abstract:BACKGROUND:We aimed to report the incidence of hospital-acquired hypophosphataemia and hyperphosphataemia along with their associated in-hospital mortality. METHODS:We included 15 869 adult patients hospitalised at a tertiary medical referral centre from January 2009 to December 2013, who had normal serum phosphate le...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2020-138872

    authors: Thongprayoon C,Cheungpasitporn W,Chewcharat A,Petnak T,Mao MA,Srivali N,Bathini T,Vallabhajosyula S,Qureshi F,Kashani K

    更新日期:2020-10-21 00:00:00

  • Prostate cancer management: (1) an update on localised disease.

    abstract::Prostate cancer is receiving ever more publicity with the result that more men are having their prostate specific antigen checked and a greater proportion of men are diagnosed with potentially curable localised disease. Advances in the therapeutic modalities including radical surgery, external beam radiotherapy, and b...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pmj.79.936.575

    authors: Bott SR,Birtle AJ,Taylor CJ,Kirby RS

    更新日期:2003-10-01 00:00:00

  • Republished paper: assessment of doctors' consultation skills in the paediatric setting: the Paediatric Consultation Assessment Tool.

    abstract:OBJECTIVE:To determine the utility of a novel Paediatric Consultation Assessment Tool (PCAT). DESIGN:Developed to measure clinicians' communication behaviour with children and their parents/guardian, PCAT was designed according to consensus guidelines and refined at a number of stages. Volunteer clinicians provided vi...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2008.146191rep

    authors: Howells RJ,Davies HA,Silverman JD,Archer JC,Mellon AF

    更新日期:2010-10-01 00:00:00

  • Novel therapeutic agents and strategies for the management of chronic kidney disease mineral and bone disorder.

    abstract::Abnormalities in the serum concentrations of calcium, phosphate, parathyroid hormone and vitamin D develop with declining renal function, leading in turn to renal osteodystrophy. Observational data now suggest that these disturbances in bone and mineral metabolism play an important role in the development of vascular ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2008.075515

    authors: Connor A

    更新日期:2009-05-01 00:00:00

  • Interventions for smoking cessation in patients admitted with Acute Coronary Syndrome: a review.

    abstract::Tobacco smoking contributes to about six million deaths per year and is predicted to increase in the future. Several pharmacological interventions are used for smoking cessation. Trials using nicotine replacement therapy (NRT) in acute coronary syndrome (ACS) showed inconclusive results. Furthermore, three trials usin...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/postgradmedj-2017-135040

    authors: Chehab OM,Dakik HA

    更新日期:2018-02-01 00:00:00

  • Gastric outlet obstruction due to gall stones (Bouveret syndrome).

    abstract::Gastric outlet obstruction by gall stone is a rare complication of a common disorder. Two cases are reported here. The investigations are conducted along the same lines as for pyloric stenosis. The diagnosis can be made with a barium meal or gastroscopy. Treatment is by surgical intervention after adequate resuscitati...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.63.744.909

    authors: Ah-Chong K,Leong YP

    更新日期:1987-10-01 00:00:00

  • Aspects of fibrocystic disease of the breast. Treatment with danazol.

    abstract::The differing aspects of fibrocystic disease are presented. The various histological components making up the breast account for the variegated presentation of symptoms and findings. Pain, tenderness and nodularity represent the greatest problem with the former two prompting the patient to seek relief. The latter symp...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章

    doi:

    authors: Humphrey LJ,Estes NC

    更新日期:1979-01-01 00:00:00

  • Elevated serum parathyroid hormone related protein and 1,25-dihydroxycholecalciferol in hypercalcaemia associated with adult T-cell leukaemia-lymphoma.

    abstract::Hypercalcaemia occurs in up to 80% of patients with adult T-cell leukaemia-lymphoma (ATLL) associated with human T-cell leukaemia virus-1 infection. Elevated serum levels of 1,25-dihydroxycholecalciferol, implicated in the pathogenesis of hypercalcaemia in lymphoma, and of parathyroid hormone-related protein (PTHrP), ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.68.803.753

    authors: Johnston SR,Hammond PJ

    更新日期:1992-09-01 00:00:00

  • Nonvalvular myocardial involvement in metastatic carcinoid disease.

    abstract::A patient with the unusual post mortem finding of myocardial metastatic carcinoid tumour without classical valvular or endocardial carcinoid disease is described. This rare occurrence may represent an aggressive type of carcinoid tumour, with metastatic disease occurring before the development of classical fibrous val...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.72.854.751

    authors: Davis G,Birbeck K,Roberts D,Naqvi N

    更新日期:1996-12-01 00:00:00

  • Role of angiotensin-converting enzyme inhibitors in early antihypertensive treatment in non-insulin dependent diabetes mellitus.

    abstract::The effect of captopril monotherapy on blood pressure and metabolism was investigated in a placebo-controlled study in 30 non-insulin dependent (Type II) diabetic subjects during a 3-week observation period (run-in/drug; placebo/wash-out) on a metabolic ward. Captopril significantly reduced both systolic and diastolic...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rett K,Wicklmayr M,Tschollar W,Dietze G,Mehnert H

    更新日期:1988-01-01 00:00:00